Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Androidâ„¢ device!
Free
Faster access than browser!
 

Desmethylclozapine and Partial agonist

Shortcuts: Differences, Similarities, Jaccard Similarity Coefficient, References.

Difference between Desmethylclozapine and Partial agonist

Desmethylclozapine vs. Partial agonist

N-Desmethylclozapine (NDMC), or norclozapine, is a major active metabolite of the atypical antipsychotic drug clozapine. In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.

Similarities between Desmethylclozapine and Partial agonist

Desmethylclozapine and Partial agonist have 3 things in common (in Unionpedia): Agonist, Aripiprazole, Intrinsic activity.

Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

Agonist and Desmethylclozapine · Agonist and Partial agonist · See more »

Aripiprazole

Aripiprazole, sold under the brand name Abilify among others, is an atypical antipsychotic. It is recommended and primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders, and irritability associated with autism. According to a Cochrane review, evidence for the oral form in schizophrenia is not sufficient to determine effects on general functioning. Additionally, because many people dropped out of the medication trials before they were completed, the overall strength of the conclusions is low. Side effects include neuroleptic malignant syndrome, a movement disorder known as tardive dyskinesia, and high blood sugar in those with diabetes. In the elderly there is an increased risk of death. It is thus not recommended for use in those with psychosis due to dementia. It is pregnancy category C in the United States and category C in Australia, meaning there is possible evidence of harm to the fetus. It is not recommended for women who are breastfeeding. It is unclear whether it is safe or effective in people less than 18 years old. It is a partial dopamine agonist. Aripiprazole was developed by Otsuka in Japan. In the United States, Otsuka America markets it jointly with Bristol-Myers Squibb. From April 2013 to March 2014, sales of Abilify amounted to almost $6.9 billion.

Aripiprazole and Desmethylclozapine · Aripiprazole and Partial agonist · See more »

Intrinsic activity

Intrinsic activity (IA) or efficacy refers to the relative ability of a drug-receptor complex to produce a maximum functional response.

Desmethylclozapine and Intrinsic activity · Intrinsic activity and Partial agonist · See more »

The list above answers the following questions

Desmethylclozapine and Partial agonist Comparison

Desmethylclozapine has 21 relations, while Partial agonist has 20. As they have in common 3, the Jaccard index is 7.32% = 3 / (21 + 20).

References

This article shows the relationship between Desmethylclozapine and Partial agonist. To access each article from which the information was extracted, please visit:

Hey! We are on Facebook now! »