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Epidermis

Index Epidermis

The epidermis is the outer layer of the three layers that make up the skin, the inner layers being the dermis and hypodermis. [1]

118 relations: Actin, Adherens junction, Antimicrobial peptides, Arteriole, Artificial skin, Atmosphere, Autocrine signalling, Bark (botany), Basement membrane, Birth, Blood, Cadherin, Calcium, Capillary, Cell division, Cell growth, Cell junction, Cell nucleus, Cell surface receptor, Cell-mediated immunity, Cellular differentiation, Central nervous system, Ceramide, Chemical substance, Chloride channel, Circulatory system, Corneocyte, Cytoplasm, Cytoskeleton, Dendrite, Dermis, Desmosome, Desquamation, Developmental biology, Drug, Embryo, Enzyme, Epithelial sodium channel, Epithelium, Exocytosis, Extracellular, Fatty acid, FGF7, Fibroblast, Fingertips, Food, Germ layer, Glucocorticoid, Glycosphingolipid, Golgi apparatus, ..., Gradient, Granularity, Granule (cell biology), Growth factor, Health, Hemidesmosome, Histology, Homo sapiens, Human skin color, Humidity, Humoral immunity, Immune system, Immunofluorescence, Infection, Integumentary system, Intracellular, Keratin, Keratinocyte, Keratinocyte growth factor, Laboratory, Lamellar bodies, Langerhans cell, Life, Lip, Lipid, Malpighian layer, Marcello Malpighi, Mechanics, Melanin, Melanocyte, Melanosome, Merkel cell, Microfilament, Microorganism, Nerve, Neurulation, Optical coherence tomography, Organogenesis, Oxidative stress, Paracrine signalling, Pathogen, PH, Phospholipid, Pigment, Protein, Psychological stress, Psychology, Rete pegs, Secretion, Skin, Skin repair, Stem cell, Sterol, Stratified squamous epithelium, Stratum basale, Stratum corneum, Stratum granulosum, Stratum lucidum, Stratum spinosum, Subcutaneous tissue, TGF alpha, Tissue (biology), Tissue hydration, Transepidermal water loss, Transforming growth factor, Ultraviolet, Venule, Vertebrate. Expand index (68 more) »

Actin

Actin is a family of globular multi-functional proteins that form microfilaments.

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Adherens junction

Adherens junctions (or zonula adherens, intermediate junction, or "belt desmosome") are protein complexes that occur at cell–cell junctions in epithelial and endothelial tissues, usually more basal than tight junctions.

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Antimicrobial peptides

Antimicrobial peptides (AMPs), also called host defense peptides (HDPs) are part of the innate immune response found among all classes of life.

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Arteriole

An arteriole is a small-diameter blood vessel in the microcirculation that extends and branches out from an artery and leads to capillaries.

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Artificial skin

Artificial skin is a collagen scaffold that induces regeneration of skin in mammals such as humans.

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Atmosphere

An atmosphere is a layer or a set of layers of gases surrounding a planet or other material body, that is held in place by the gravity of that body.

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Autocrine signalling

Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine receptors on that same cell, leading to changes in the cell.

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Bark (botany)

Bark is the outermost layers of stems and roots of woody plants.

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Basement membrane

The basement membrane is a thin, fibrous, extracellular matrix of tissue that separates the lining of an internal or external body surface from underlying connective tissue in metazoans.

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Birth

Birth is the act or process of bearing or bringing forth offspring.

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Blood

Blood is a body fluid in humans and other animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells.

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Cadherin

Cadherins (named for "calcium-dependent adhesion") are a type of cell adhesion molecule (CAM) that is important in the formation of adherens junctions to bind cells with each other.

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Calcium

Calcium is a chemical element with symbol Ca and atomic number 20.

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Capillary

A capillary is a small blood vessel from 5 to 10 micrometres (µm) in diameter, and having a wall one endothelial cell thick.

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Cell division

Cell division is the process by which a parent cell divides into two or more daughter cells.

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Cell growth

The term cell growth is used in the contexts of biological cell development and cell division (reproduction).

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Cell junction

A cell junction (or intercellular bridge) is a type of structure that exists within the tissue of some multicellular organisms, such as animals.

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Cell nucleus

In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.

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Cell surface receptor

Cell surface receptors (membrane receptors, transmembrane receptors) are receptors that are embedded in the membranes of cells.

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Cell-mediated immunity

Cell-mediated immunity is an immune response that does not involve antibodies, but rather involves the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen.

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Cellular differentiation

In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another.

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Ceramide

Ceramides are a family of waxy lipid molecules.

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Chemical substance

A chemical substance, also known as a pure substance, is a form of matter that consists of molecules of the same composition and structure.

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Chloride channel

Chloride channels are a superfamily of poorly understood ion channels specific for chloride.

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Circulatory system

The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.

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Corneocyte

Corneocytes are terminally differentiated keratinocytes and compose most if not all of the stratum corneum, the outermost part of the epidermis.

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Cytoplasm

In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.

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Cytoskeleton

A cytoskeleton is present in all cells of all domains of life (archaea, bacteria, eukaryotes).

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Dendrite

Dendrites (from Greek δένδρον déndron, "tree"), also dendrons, are branched protoplasmic extensions of a nerve cell that propagate the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project.

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Dermis

The dermis or corium is a layer of skin between the epidermis (with which it makes up the cutis) and subcutaneous tissues, that primarily consists of dense irregular connective tissue and cushions the body from stress and strain.

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Desmosome

A desmosome ("binding body"), also known as a macula adhaerens (plural: maculae adhaerentes) (Latin for adhering spot), is a cell structure specialized for cell-to-cell adhesion.

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Desquamation

Desquamation, also called skin peeling, is the shedding of the outermost membrane or layer of a tissue, such as the skin.

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Developmental biology

Developmental biology is the study of the process by which animals and plants grow and develop.

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Drug

A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.

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Embryo

An embryo is an early stage of development of a multicellular diploid eukaryotic organism.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Epithelial sodium channel

The epithelial sodium channel (short: eNaC, also: amiloride-sensitive sodium channel) is a membrane-bound ion channel that is selectively permeable to Na+ ions and that is assembled as a heterotrimer composed of three homologous subunits α or δ, β, and γ, These subunits are encoded by four genes: SCNN1A, SCNN1B, SCNN1G, and SCNN1D.

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.

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Exocytosis

Exocytosis is a form of active transport in which a cell transports molecules (e.g., neurotransmitters and proteins) out of the cell (exo- + cytosis) by expelling them through an energy-dependent process.

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Extracellular

In cell biology, molecular biology and related fields, the word extracellular (or sometimes extracellular space) means "outside the cell".

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Fatty acid

In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with a long aliphatic chain, which is either saturated or unsaturated.

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FGF7

Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene.

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Fibroblast

A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.

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Fingertips

"Fingertips" is a 1963 hit single recorded live by "Little" Stevie Wonder for Motown's then Tamla label.

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Food

Food is any substance consumed to provide nutritional support for an organism.

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Germ layer

A germ layer is a primary layer of cells that form during embryogenesis.

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Glucocorticoid

Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.

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Glycosphingolipid

Glycosphingolipids are a subtype of glycolipids containing the amino alcohol sphingosine.

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Golgi apparatus

The Golgi apparatus, also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells.

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Gradient

In mathematics, the gradient is a multi-variable generalization of the derivative.

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Granularity

Granularity (also called graininess), the condition of existing in grains or granules, refers to the extent to which a material or system is composed of distinguishable pieces or grains.

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Granule (cell biology)

In cell biology, a granule is a small particle.

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Growth factor

A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.

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Health

Health is the ability of a biological system to acquire, convert, allocate, distribute, and utilize energy with maximum efficiency.

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Hemidesmosome

Hemidesmosomes (HD) are very small stud-like structures found in keratinocytes of the epidermis of skin that attach to the extracellular matrix (ECM).

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Histology

Histology, also microanatomy, is the study of the anatomy of cells and tissues of plants and animals using microscopy.

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Homo sapiens

Homo sapiens is the systematic name used in taxonomy (also known as binomial nomenclature) for the only extant human species.

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Human skin color

Human skin color ranges in variety from the darkest brown to the lightest hues.

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Humidity

Humidity is the amount of water vapor present in the air.

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Humoral immunity

Humoral immunity or humoural immunity is the aspect of immunity that is mediated by macromolecules found in extracellular fluids such as secreted antibodies, complement proteins, and certain antimicrobial peptides.

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Immune system

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.

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Immunofluorescence

Immunofluorescence is a technique used for light microscopy with a fluorescence microscope and is used primarily on microbiological samples.

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Infection

Infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce.

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Integumentary system

The integumentary system comprises the skin and its appendages acting to protect the body from various kinds of damage, such as loss of water or abrasion from outside.

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Intracellular

In cell biology, molecular biology and related fields, the word intracellular means "inside the cell".

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Keratin

Keratin is one of a family of fibrous structural proteins.

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Keratinocyte

A keratinocyte is the predominant cell type in the epidermis, the outermost layer of the skin, constituting 90% of the cells found there.

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Keratinocyte growth factor

The keratinocyte growth factor (KGF), also known as FGF7, is a growth factor present in the epithelialization-phase of wound healing.

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Laboratory

A laboratory (informally, lab) is a facility that provides controlled conditions in which scientific or technological research, experiments, and measurement may be performed.

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Lamellar bodies

In cell biology, lamellar bodies (otherwise known as lamellar granules, membrane-coating granules (MCGs), keratinosomes or Odland bodies) are secretory organelles found in type II alveolar cells in the lungs, and in keratinocytes in the skin.

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Langerhans cell

Langerhans cells are dendritic cells (antigen-presenting immune cells) of the skin, and contain organelles called Birbeck granules.

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Life

Life is a characteristic that distinguishes physical entities that do have biological processes, such as signaling and self-sustaining processes, from those that do not, either because such functions have ceased, or because they never had such functions and are classified as inanimate.

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Lip

Lips are a visible body part at the mouth of humans and many animals.

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Lipid

In biology and biochemistry, a lipid is a biomolecule that is soluble in nonpolar solvents.

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Malpighian layer

The Malpighian layer of the skin is generally defined as both the stratum basale and stratum spinosum as a unit,McGrath, J.A.; Eady, R.A.; Pope, F.M. (2004).

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Marcello Malpighi

Marcello Malpighi (10 March 1628 – 29 November 1694) was an Italian biologist and physician, who is referred to as the "Father of microscopical anatomy, histology, physiology and embryology".

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Mechanics

Mechanics (Greek μηχανική) is that area of science concerned with the behaviour of physical bodies when subjected to forces or displacements, and the subsequent effects of the bodies on their environment.

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Melanin

Melanin (from μέλας melas, "black, dark") is a broad term for a group of natural pigments found in most organisms.

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Melanocyte

Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), the inner ear, vaginal epithelium, meninges, bones, and heart.

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Melanosome

A melanosome is an organelle found in animal cells and is the site for synthesis, storage and transport of melanin, the most common light-absorbing pigment found in the animal kingdom.

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Merkel cell

Merkel cells, also known as Merkel-Ranvier cells or tactile epithelial cells, are oval-shaped mechanoreceptors essential for light touch sensation and found in the skin of vertebrates.

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Microfilament

Microfilaments, also called actin filaments, are filaments in the cytoplasm of eukaryotic cells that form part of the cytoskeleton.

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Microorganism

A microorganism, or microbe, is a microscopic organism, which may exist in its single-celled form or in a colony of cells. The possible existence of unseen microbial life was suspected from ancient times, such as in Jain scriptures from 6th century BC India and the 1st century BC book On Agriculture by Marcus Terentius Varro. Microbiology, the scientific study of microorganisms, began with their observation under the microscope in the 1670s by Antonie van Leeuwenhoek. In the 1850s, Louis Pasteur found that microorganisms caused food spoilage, debunking the theory of spontaneous generation. In the 1880s Robert Koch discovered that microorganisms caused the diseases tuberculosis, cholera and anthrax. Microorganisms include all unicellular organisms and so are extremely diverse. Of the three domains of life identified by Carl Woese, all of the Archaea and Bacteria are microorganisms. These were previously grouped together in the two domain system as Prokaryotes, the other being the eukaryotes. The third domain Eukaryota includes all multicellular organisms and many unicellular protists and protozoans. Some protists are related to animals and some to green plants. Many of the multicellular organisms are microscopic, namely micro-animals, some fungi and some algae, but these are not discussed here. They live in almost every habitat from the poles to the equator, deserts, geysers, rocks and the deep sea. Some are adapted to extremes such as very hot or very cold conditions, others to high pressure and a few such as Deinococcus radiodurans to high radiation environments. Microorganisms also make up the microbiota found in and on all multicellular organisms. A December 2017 report stated that 3.45 billion year old Australian rocks once contained microorganisms, the earliest direct evidence of life on Earth. Microbes are important in human culture and health in many ways, serving to ferment foods, treat sewage, produce fuel, enzymes and other bioactive compounds. They are essential tools in biology as model organisms and have been put to use in biological warfare and bioterrorism. They are a vital component of fertile soils. In the human body microorganisms make up the human microbiota including the essential gut flora. They are the pathogens responsible for many infectious diseases and as such are the target of hygiene measures.

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Nerve

A nerve is an enclosed, cable-like bundle of axons (nerve fibers, the long and slender projections of neurons) in the peripheral nervous system.

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Neurulation

Neurulation refers to the folding process in vertebrate embryos, which includes the transformation of the neural plate into the neural tube.

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Optical coherence tomography

Optical coherence tomography (OCT) is an imaging technique that uses coherent light to capture micrometer-resolution, two- and three-dimensional images from within optical scattering media (e.g., biological tissue).

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Organogenesis

In animal development, organogenesis is the phase of embryonic development that starts at the end of gastrulation and goes until birth.

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Oxidative stress

Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage.

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Paracrine signalling

Paracrine signaling is a form of cell-to-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior of those cells.

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Pathogen

In biology, a pathogen (πάθος pathos "suffering, passion" and -γενής -genēs "producer of") or a '''germ''' in the oldest and broadest sense is anything that can produce disease; the term came into use in the 1880s.

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PH

In chemistry, pH is a logarithmic scale used to specify the acidity or basicity of an aqueous solution.

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Phospholipid

Phospholipids are a class of lipids that are a major component of all cell membranes.

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Pigment

A pigment is a material that changes the color of reflected or transmitted light as the result of wavelength-selective absorption.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Psychological stress

In psychology, stress is a feeling of strain and pressure.

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Psychology

Psychology is the science of behavior and mind, including conscious and unconscious phenomena, as well as feeling and thought.

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Rete pegs

Rete pegs (also known as rete processes or rete ridges) are the epithelial extensions that project into the underlying connective tissue in both skin and mucous membranes.

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Secretion

Secretion is the movement of material from one point to another, e.g. secreted chemical substance from a cell or gland.

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Skin

Skin is the soft outer tissue covering vertebrates.

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Skin repair

Protection from mechanical injury, chemical hazards, and bacterial invasion is provided by the skin because the epidermis is relatively thick and covered with keratin.

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Stem cell

Stem cells are biological cells that can differentiate into other types of cells and can divide to produce more of the same type of stem cells.

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Sterol

Sterols, also known as steroid alcohols, are a subgroup of the steroids and an important class of organic molecules.

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Stratified squamous epithelium

A stratified squamous epithelium consists of squamous (flattened) epithelial cells arranged in layers upon a basal membrane.

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Stratum basale

The stratum basale (basal layer, sometimes referred to as stratum germinativum) is the deepest layer of the five layers of the epidermis, the outer covering of skin in mammals.

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Stratum corneum

The stratum corneum (Latin for 'horny layer') is the outermost layer of the epidermis, consisting of dead cells (corneocytes).

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Stratum granulosum

The stratum granulosum (or granular layer) is a thin layer of cells in the epidermis.

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Stratum lucidum

The stratum lucidum (Latin for "clear layer") is a thin, clear layer of dead skin cells in the epidermis named for its translucent appearance under a microscope.

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Stratum spinosum

The stratum spinosum (or spinous layer/prickle cell layer) is a layer of the epidermis found between the stratum granulosum and stratum basale.

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Subcutaneous tissue

The subcutaneous tissue, also called the hypodermis, hypoderm, subcutis, or superficial fascia, is the lowermost layer of the integumentary system in vertebrates.

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TGF alpha

Transforming growth factor alpha (TGF-α) is a protein that in humans is encoded by the TGFA gene.

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Tissue (biology)

In biology, tissue is a cellular organizational level between cells and a complete organ.

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Tissue hydration

Tissue hydration is the process of absorbing and retaining water in biological tissues.

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Transepidermal water loss

Transepidermal water loss (TEWL or TWL) is the loss of water that passes from inside a body (animal or plant) through the epidermis (that is, either the epidermal layer of animal skin or the epidermal layer of plants) to the surrounding atmosphere via diffusion and evaporation processes.

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Transforming growth factor

Transforming growth factor (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ.

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Ultraviolet

Ultraviolet (UV) is electromagnetic radiation with a wavelength from 10 nm to 400 nm, shorter than that of visible light but longer than X-rays.

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Venule

A venule is a very small blood vessel in the microcirculation that allows blood to return from the capillary beds to drain into the larger blood vessels, the veins.

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Vertebrate

Vertebrates comprise all species of animals within the subphylum Vertebrata (chordates with backbones).

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Epidermal, Epidermal cell, Epidermis (skin), Epidermotropic, Lower Epidermis, Placoda epidermis, Reconstructed Human Epidermis, Reconstructed human epidermis, Rete ridge, Rete ridges, Rete tip, Upper Epidermis.

References

[1] https://en.wikipedia.org/wiki/Epidermis

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