Estriol and Estrone

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Difference between Estriol and Estrone

Estriol vs. Estrone

Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone. Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone.

Adrenal gland

The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.

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Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Androstenedione

Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA).

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Aromatase

Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens.

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Biotransformation

Biotransformation is the chemical modification (or modifications) made by an organism on a chemical compound.

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Cholesterol

Cholesterol (from the Ancient Greek chole- (bile) and stereos (solid), followed by the chemical suffix -ol for an alcohol) is an organic molecule.

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Circulatory system

The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.

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Cytochrome P450

Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.

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Double bond

A double bond in chemistry is a chemical bond between two chemical elements involving four bonding electrons instead of the usual two.

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Endogeny (biology)

Endogenous substances and processes are those that originate from within an organism, tissue, or cell.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Estradiol

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.

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Estrane

Estrane is a C18 steroid derivative, with a gonane core.

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Estrin (compound)

Estrin (American English), or oestrin (British English), also known as estra-1,3,5(10)-triene, is an estrane steroid.

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Estrogen

Estrogen, or oestrogen, is the primary female sex hormone.

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Estrogen receptor

Estrogen receptors (ERs) are a group of proteins found inside cells.

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Estrogen receptor alpha

Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.

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Estrogen receptor beta

Estrogen receptor beta (ER-β), also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2), is one of two main types of estrogen receptor, a nuclear receptor which is activated by the sex hormone estrogen.

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Excretion

Excretion is the process by which metabolic waste is eliminated from an organism.

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Hydroxy group

A hydroxy or hydroxyl group is the entity with the formula OH.

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Hydroxylation

Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound.

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In vivo

Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

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Intrinsic activity

Intrinsic activity (IA) or efficacy refers to the relative ability of a drug-receptor complex to produce a maximum functional response.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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Medication

A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Menopause

Menopause, also known as the climacteric, is the time in most women's lives when menstrual periods stop permanently, and they are no longer able to bear children.

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Natural product

A natural product is a chemical compound or substance produced by a living organism—that is, found in nature.

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Postmenopausal hormone therapy

Menopausal hormone therapy (MHT), or postmenopausal hormone therapy (PHT, PMHT), also known as hormone replacement therapy in menopause, is a form of hormone replacement therapy (HRT) which is used in postmenopausal, perimenopausal, and surgically menopausal women.

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Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

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Pregnancy

Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.

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Sex hormone-binding globulin

Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to the two sex hormones: androgen and estrogen.

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Sex steroid

Sex steroids, also known as gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate androgen or estrogen receptors.

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Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Urine

Urine is a liquid by-product of metabolism in humans and in many animals.

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17β-Hydroxysteroid dehydrogenase

17β-Hydroxysteroid dehydrogenases (17β-HSD, HSD17B), also 17-ketosteroid reductases (17-KSR), are a group of alcohol oxidoreductases which catalyze the reduction of 17-ketosteroids and the dehydrogenation of 17β-hydroxysteroids in steroidogenesis and steroid metabolism.

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