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Folin–Ciocalteu reagent

Index Folin–Ciocalteu reagent

The Folin–Ciocalteu reagent (FCR) or Folin's phenol reagent or Folin–Denis reagent, also called the gallic acid equivalence method (GAE), is a mixture of phosphomolybdate and phosphotungstate used for the colorimetric in vitro assay of phenolic and polyphenolic antioxidants. [1]

29 relations: Antioxidant effect of polyphenols and natural phenols, Assay, Biology, Citation, Dihydroxyacetone, Folin's reagent, Food science, Free-radical theory of aging, Gallic acid, Glyceraldehyde, Guanidine, Guanine, Hydroxylamine, In vitro, In vivo, Journal of Agricultural and Food Chemistry, Journal of Biological Chemistry, Lowry protein assay, Otto Folin, Oxygen radical absorbance capacity, Phosphomolybdic acid, Phosphotungstic acid, Polyphenol, Science Citation Index, Triose, Trolox equivalent antioxidant capacity, United States Department of Agriculture, Vintilă Ciocâlteu, Willey Glover Denis.

Antioxidant effect of polyphenols and natural phenols

A polyphenol antioxidant is a type of antioxidant containing a polyphenolic substructure and studied in vitro.

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Assay

An assay is an investigative (analytic) procedure in laboratory medicine, pharmacology, environmental biology and molecular biology for qualitatively assessing or quantitatively measuring the presence, amount, or functional activity of a target entity (the analyte).

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Biology

Biology is the natural science that studies life and living organisms, including their physical structure, chemical composition, function, development and evolution.

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Citation

A citation is a reference to a published or unpublished source (not always the original source).

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Dihydroxyacetone

Dihydroxyacetone, or DHA, also known as glycerone, is a simple saccharide (a triose) with formula.

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Folin's reagent

Folin's reagent or sodium 1,2-naphthoquinone-4-sulfonate is a chemical reagent used as a derivatizing agent to measure levels of amines and amino acids.

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Food science

Food science is the applied science devoted to the study of food.

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Free-radical theory of aging

The free radical theory of aging (FRTA) states that organisms age because cells accumulate free radical damage over time.

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Gallic acid

Gallic acid (also known as 3,4,5-trihydroxybenzoic acid) is a trihydroxybenzoic acid, a type of phenolic acid, found in gallnuts, sumac, witch hazel, tea leaves, oak bark, and other plants.

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Glyceraldehyde

Glyceraldehyde (glyceral) is a triose monosaccharide with chemical formula C3H6O3.

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Guanidine

Guanidine is the compound with the formula HNC(NH2)2.

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Guanine

Guanine (or G, Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA).

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Hydroxylamine

Hydroxylamine is an inorganic compound with the formula NH2OH.

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In vitro

In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

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In vivo

Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

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Journal of Agricultural and Food Chemistry

The Journal of Agricultural and Food Chemistry is a weekly peer-reviewed scientific journal established in 1953 by the American Chemical Society.

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Journal of Biological Chemistry

The Journal of Biological Chemistry is a weekly peer-reviewed scientific journal that was established in 1905.

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Lowry protein assay

The Lowry protein assay is a biochemical assay for determining the total level of protein in a solution.

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Otto Folin

Otto Knut Olof Folin (April 4, 1867 – October 25, 1934) was a Swedish-born American chemist who is best known for his groundbreaking work at Harvard University on practical micromethods for the determination of the constituents of protein-free blood filtrates and the discovery of creatine phosphate in muscles.

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Oxygen radical absorbance capacity

Oxygen radical absorbance capacity (ORAC) is a method of measuring antioxidant capacities in biological samples in vitro.

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Phosphomolybdic acid

Phosphomolybdic acid, also known as dodeca molybdophosphoric acid or PMA is a component of Masson's trichrome stain.

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Phosphotungstic acid

Phosphotungstic acid (PTA), tungstophosphoric acid (TPA), is a heteropoly acid with the chemical formula 31240.

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Polyphenol

Polyphenols (also known as polyhydroxyphenols) are a structural class of mainly natural, but also synthetic or semisynthetic, organic chemicals characterized by the presence of large multiples of phenol structural units.

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Science Citation Index

The Science Citation Index (SCI) is a citation index originally produced by the Institute for Scientific Information (ISI) and created by Eugene Garfield.

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Triose

A triose is a monosaccharide, or simple sugar, containing three carbon atoms.

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Trolox equivalent antioxidant capacity

Trolox equivalent antioxidant capacity (TEAC) measures the antioxidant capacity of a given substance, as compared to the standard, Trolox.

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United States Department of Agriculture

The United States Department of Agriculture (USDA), also known as the Agriculture Department, is the U.S. federal executive department responsible for developing and executing federal laws related to farming, forestry, and food.

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Vintilă Ciocâlteu

Vintilă Ciocâlteu (Dolj, April 12, 1890 – Bucharest, February 3, 1947) was a Romanian physician, researcher, professor and author.

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Willey Glover Denis

Willey Glover Denis (February 26, 1879 – January 9, 1929) was an American biochemist and physiologist.

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Folin method, Folin's phenol reagent, Folin-Ciocalteau assay, Folin-Ciocalteu, Folin-Ciocalteu polyphenol test, Folin-Ciocalteu reaction, Folin-Ciocalteu reagent, Folin-Ciocalteu's reagent, Folin-Denis, Folin-Denis reagent, Folin-Lowry, Folin-phenol reagent, Gallic Acid Equivalence method, Gallic acid equivalence method, Gallic acid equivalents, Phenolic antioxidant.

References

[1] https://en.wikipedia.org/wiki/Folin–Ciocalteu_reagent

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