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GPER

Index GPER

G protein-coupled estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans is encoded by the GPER gene. [1]

68 relations: Adrenal medulla, Aldosterone, Antidepressant, Anxiogenic, Anxiolytic, Biomarker, Blood pressure, Bone, Breast, Breast development, CCL18, Cell growth, Cortisol, Endogeny (biology), Endoplasmic reticulum, Endothelium, Epithelium, ER-X, ERx, Estradiol, Estriol, Estrogen, Estrogen receptor, Estrogen receptor alpha, Estrogen receptor beta, Estrone, Fertility, Fulvestrant, G protein–coupled receptor, Gene, Gene expression, Germ cell, Gonadotropin-releasing hormone, Gq-mER, Hyperglycemia, Hypothalamic–pituitary–gonadal axis, Hypothalamus, Impaired glucose tolerance, Intracellular, Knockout mouse, Lordosis, Mammary gland, Membrane estrogen receptor, Metabolite, Niacin, Nicotinamide, Nuclear receptor, Osteoblast, Ovarian follicle, Oxytocin, ..., Oxytocin receptor, Paraventricular nucleus of hypothalamus, Phenotype, Phosphatidylinositol (3,4,5)-trisphosphate, Pituitary gland, Progesterone, Protein, Renal medulla, Renin–angiotensin system, Rhodopsin, Spermatogenesis, Supraoptic nucleus, Tamoxifen, Testosterone, Transcription (biology), Transcription factor, Triple-negative breast cancer, Vasodilation. Expand index (18 more) »

Adrenal medulla

The adrenal medulla (medulla glandulae suprarenalis) is part of the adrenal gland.

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Aldosterone

Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.

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Antidepressant

Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.

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Anxiogenic

An anxiogenic or panicogenic substance is one that causes anxiety.

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Anxiolytic

An anxiolytic (also antipanic or antianxiety agent) is a medication or other intervention that inhibits anxiety.

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Biomarker

A biomarker, or biological marker, generally refers to a measurable indicator of some biological state or condition.

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Blood pressure

Blood pressure (BP) is the pressure of circulating blood on the walls of blood vessels.

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Bone

A bone is a rigid organ that constitutes part of the vertebrate skeleton.

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Breast

The breast is one of two prominences located on the upper ventral region of the torso of primates.

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Breast development

Breast development, also known as mammogenesis, is a complex biological process in primates that takes place throughout a female's life.

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CCL18

Chemokine (C-C motif) ligand 18 (CCL18) is a small cytokine belonging to the CC chemokine family.

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Cell growth

The term cell growth is used in the contexts of biological cell development and cell division (reproduction).

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Cortisol

Cortisol is a steroid hormone, in the glucocorticoid class of hormones.

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Endogeny (biology)

Endogenous substances and processes are those that originate from within an organism, tissue, or cell.

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Endoplasmic reticulum

The endoplasmic reticulum (ER) is a type of organelle found in eukaryotic cells that forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.

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ER-X

ER-X is a membrane-associated receptor that is bound and activated by 17α-estradiol and 17β-estradiol and is a putative membrane estrogen receptor (mER).

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ERx

ERx is a putative membrane estrogen receptor (mER) of which little is currently known.

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Estradiol

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.

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Estriol

Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone.

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Estrogen

Estrogen, or oestrogen, is the primary female sex hormone.

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Estrogen receptor

Estrogen receptors (ERs) are a group of proteins found inside cells.

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Estrogen receptor alpha

Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.

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Estrogen receptor beta

Estrogen receptor beta (ER-β), also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2), is one of two main types of estrogen receptor, a nuclear receptor which is activated by the sex hormone estrogen.

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Estrone

Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone.

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Fertility

Fertility is the natural capability to produce offspring.

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Fulvestrant

Fulvestrant, sold under the brand name Faslodex among others, is a medication used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women with disease progression as well as HR-positive, HER2-negative advanced breast cancer in combination with palbociclib in women with disease progression after endocrine therapy.

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G protein–coupled receptor

G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.

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Germ cell

A germ cell is any biological cell that gives rise to the gametes of an organism that reproduces sexually.

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Gonadotropin-releasing hormone

Gonadotropin-releasing hormone (GnRH) also known as gonadoliberin, and by various other names in its endogenous form and as gonadorelin in its pharmaceutical form, is a releasing hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.

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Gq-mER

Gq-mER is a G protein-coupled receptor present in the hypothalamus that has not yet been cloned.

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Hyperglycemia

Hyperglycemia, or high blood sugar (also spelled hyperglycaemia or hyperglycæmia) is a condition in which an excessive amount of glucose circulates in the blood plasma.

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Hypothalamic–pituitary–gonadal axis

The hypothalamic–pituitary–gonadal axis (HPG axis) refers to the hypothalamus, pituitary gland, and gonadal glands as if these individual endocrine glands were a single entity.

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Hypothalamus

The hypothalamus(from Greek ὑπό, "under" and θάλαμος, thalamus) is a portion of the brain that contains a number of small nuclei with a variety of functions.

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Impaired glucose tolerance

Impaired glucose tolerance (IGT) is a pre-diabetic state of hyperglycemia that is associated with insulin resistance and increased risk of cardiovascular pathology.

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Intracellular

In cell biology, molecular biology and related fields, the word intracellular means "inside the cell".

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Knockout mouse

A knockout mouse or knock-out mouse is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA.

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Lordosis

Lordosis is the normal inward lordotic curvature of the lumbar and cervical regions of the human spine.

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Mammary gland

A mammary gland is an exocrine gland in mammals that produces milk to feed young offspring.

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Membrane estrogen receptor

Membrane estrogen receptors (mERs) are a group of receptors which bind estrogen.

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Metabolite

A metabolite is the intermediate end product of metabolism.

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Niacin

Niacin, also known as nicotinic acid, is an organic compound and a form of vitamin B3, an essential human nutrient.

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Nicotinamide

Nicotinamide (NAA), also known as niacinamide, is a form of vitamin B3 found in food and used as a dietary supplement and medication.

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Nuclear receptor

In the field of molecular biology, nuclear receptors are a class of proteins found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules.

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Osteoblast

Osteoblasts (from the Greek combining forms for "bone", ὀστέο-, osteo- and βλαστάνω, blastanō "germinate") are cells with a single nucleus that synthesize bone.

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Ovarian follicle

An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries.

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Oxytocin

Oxytocin (Oxt) is a peptide hormone and neuropeptide.

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Oxytocin receptor

The oxytocin receptor, also known as OXTR, is a protein which functions as receptor for the hormone and neurotransmitter oxytocin.

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Paraventricular nucleus of hypothalamus

The paraventricular nucleus (PVN, PVA, or PVH) is a nucleus in the hypothalamus.

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Phenotype

A phenotype is the composite of an organism's observable characteristics or traits, such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior (such as a bird's nest).

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Phosphatidylinositol (3,4,5)-trisphosphate

Phosphatidylinositol (3,4,5)-trisphosphate (PtdIns(3,4,5)P3), abbreviated PIP3, is the product of the class I phosphoinositide 3-kinases (PI 3-kinases) phosphorylation of phosphatidylinositol (4,5)-bisphosphate (PIP2).

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Pituitary gland

An explanation of the development of the pituitary gland (Hypophysis cerebri) & the congenital anomalies. In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland about the size of a pea and weighing in humans.

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Progesterone

Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Renal medulla

The renal medulla is the innermost part of the kidney.

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Renin–angiotensin system

The renin–angiotensin system (RAS) or the renin–angiotensin–aldosterone system (RAAS) is a hormone system that regulates blood pressure and fluid balance.

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Rhodopsin

Rhodopsin (also known as visual purple) is a light-sensitive receptor protein involved in visual phototransduction.

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Spermatogenesis

Spermatogenesis is the process by which haploid spermatozoa develop from germ cells in the seminiferous tubules of the testis.

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Supraoptic nucleus

The supraoptic nucleus (SON) is a nucleus of magnocellular neurosecretory cells in the hypothalamus of the mammalian brain.

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Tamoxifen

Tamoxifen (TMX), sold under the brand name Nolvadex among others, is a medication that is used to prevent breast cancer in women and treat breast cancer in women and men.

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Testosterone

Testosterone is the primary male sex hormone and an anabolic steroid.

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Transcription (biology)

Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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Triple-negative breast cancer

Triple-negative breast cancer (sometimes abbreviated TNBC) refers to any breast cancer that does not express the genes for estrogen receptor (ER), progesterone receptor (PR) and Her2/neu.

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Vasodilation

Vasodilation is the widening of blood vessels.

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Redirects here:

G Protein-coupled Estrogen Receptor 1, G protein-coupled estrogen receptor, G protein-coupled estrogen receptor 1, G protein-coupled receptor 30, GPER (gene), GPR30.

References

[1] https://en.wikipedia.org/wiki/GPER

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