Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Android™ device!
Install
Faster access than browser!
 

Gabapentin and Pregabalin

Shortcuts: Differences, Similarities, Jaccard Similarity Coefficient, References.

Difference between Gabapentin and Pregabalin

Gabapentin vs. Pregabalin

Gabapentin, sold under the brand name Neurontin among others, is a medication which is used to treat epilepsy (specifically partial seizures), neuropathic pain, hot flashes, and restless legs syndrome. Pregabalin, marketed under the brand name Lyrica among others, is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder.

Similarities between Gabapentin and Pregabalin

Gabapentin and Pregabalin have 79 things in common (in Unionpedia): Absorption (pharmacology), Active transport, Alcohol withdrawal syndrome, Amino acid, Analgesic, Anticonvulsant, Anxiety disorder, Anxiolytic, Ataxia, Binding selectivity, Bioavailability, Biological half-life, Blood–brain barrier, Brain, CACNA2D1, CACNA2D2, Calcium channel, CD98, Central nervous system, Cerebrospinal fluid, Channel blocker, Chemical structure, Chemical synthesis, Cmax (pharmacology), Competitive inhibition, Derivative (chemistry), Diabetic neuropathy, Drug tolerance, Drug withdrawal, Elimination (pharmacology), ..., Endogeny (biology), Enzyme, Epilepsy, Epileptic seizure, Focal seizure, Food and Drug Administration, GABA analogue, GABA receptor, GABA receptor agonist, Gabapentinoid, Gastrointestinal tract, Generic drug, IC50, In vivo, Insomnia, Isoleucine, Kidney, Kidney failure, Leucine, Ligand (biochemistry), Lipophilicity, Low back pain, Medicine, Metabolism, Molar concentration, Neuropathic pain, Neurotransmitter transporter, Obsessive–compulsive disorder, Opioid, Oral administration, Parke-Davis, Pfizer, Pharmacodynamics, Pharmacokinetics, Phenylalanine, Plasma protein binding, Postherpetic neuralgia, Recreational drug use, Restless legs syndrome, Saturation (chemistry), Side effect, Somnolence, Structural analog, Substance abuse, The New York Times, Urine, Venlafaxine, Voltage-gated calcium channel, Warner–Lambert. Expand index (49 more) »

Absorption (pharmacology)

In pharmacology (and more specifically pharmacokinetics), absorption is the movement of a drug from the site of administration to bloodstream.

Absorption (pharmacology) and Gabapentin · Absorption (pharmacology) and Pregabalin · See more »

Active transport

Active transport is the movement of molecules across a membrane from a region of their lower concentration to a region of their higher concentration—in the direction against the concentration gradient.

Active transport and Gabapentin · Active transport and Pregabalin · See more »

Alcohol withdrawal syndrome

Alcohol withdrawal syndrome is a set of symptoms that can occur following a reduction in alcohol use after a period of excessive use.

Alcohol withdrawal syndrome and Gabapentin · Alcohol withdrawal syndrome and Pregabalin · See more »

Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

Amino acid and Gabapentin · Amino acid and Pregabalin · See more »

Analgesic

An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.

Analgesic and Gabapentin · Analgesic and Pregabalin · See more »

Anticonvulsant

Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.

Anticonvulsant and Gabapentin · Anticonvulsant and Pregabalin · See more »

Anxiety disorder

Anxiety disorders are a group of mental disorders characterized by significant feelings of anxiety and fear.

Anxiety disorder and Gabapentin · Anxiety disorder and Pregabalin · See more »

Anxiolytic

An anxiolytic (also antipanic or antianxiety agent) is a medication or other intervention that inhibits anxiety.

Anxiolytic and Gabapentin · Anxiolytic and Pregabalin · See more »

Ataxia

Ataxia is a neurological sign consisting of lack of voluntary coordination of muscle movements that includes gait abnormality.

Ataxia and Gabapentin · Ataxia and Pregabalin · See more »

Binding selectivity

Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.

Binding selectivity and Gabapentin · Binding selectivity and Pregabalin · See more »

Bioavailability

In pharmacology, bioavailability (BA or F) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.

Bioavailability and Gabapentin · Bioavailability and Pregabalin · See more »

Biological half-life

The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.

Biological half-life and Gabapentin · Biological half-life and Pregabalin · See more »

Blood–brain barrier

The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).

Blood–brain barrier and Gabapentin · Blood–brain barrier and Pregabalin · See more »

Brain

The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.

Brain and Gabapentin · Brain and Pregabalin · See more »

CACNA2D1

Voltage-dependent calcium channel subunit alpha-2/delta-1 is a protein that in humans is encoded by the CACNA2D1 gene.

CACNA2D1 and Gabapentin · CACNA2D1 and Pregabalin · See more »

CACNA2D2

Voltage-dependent calcium channel subunit alpha2delta-2 is a protein that in humans is encoded by the CACNA2D2 gene.

CACNA2D2 and Gabapentin · CACNA2D2 and Pregabalin · See more »

Calcium channel

A calcium channel is an ion channel which shows selective permeability to calcium ions.

Calcium channel and Gabapentin · Calcium channel and Pregabalin · See more »

CD98

CD98 is a glycoprotein that is a heterodimer composed of SLC3A2 and SLC7A5 that forms the large neutral amino acid transporter (LAT1).

CD98 and Gabapentin · CD98 and Pregabalin · See more »

Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

Central nervous system and Gabapentin · Central nervous system and Pregabalin · See more »

Cerebrospinal fluid

Cerebrospinal fluid (CSF) is a clear, colorless body fluid found in the brain and spinal cord.

Cerebrospinal fluid and Gabapentin · Cerebrospinal fluid and Pregabalin · See more »

Channel blocker

A channel blocker is the biological mechanism in which a particular molecule is used to prevent the opening of ion channels in order to produce a physiological response in a cell.

Channel blocker and Gabapentin · Channel blocker and Pregabalin · See more »

Chemical structure

A chemical structure determination includes a chemist's specifying the molecular geometry and, when feasible and necessary, the electronic structure of the target molecule or other solid.

Chemical structure and Gabapentin · Chemical structure and Pregabalin · See more »

Chemical synthesis

Chemical synthesis is a purposeful execution of chemical reactions to obtain a product, or several products.

Chemical synthesis and Gabapentin · Chemical synthesis and Pregabalin · See more »

Cmax (pharmacology)

Cmax is the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administrated and before the administration of a second dose.

Cmax (pharmacology) and Gabapentin · Cmax (pharmacology) and Pregabalin · See more »

Competitive inhibition

Competitive inhibition is a form of enzyme inhibition where binding of an inhibitor prevents binding of the target molecule of the enzyme, also known as the substrate.

Competitive inhibition and Gabapentin · Competitive inhibition and Pregabalin · See more »

Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

Derivative (chemistry) and Gabapentin · Derivative (chemistry) and Pregabalin · See more »

Diabetic neuropathy

Diabetic neuropathies are nerve damaging disorders associated with diabetes mellitus.

Diabetic neuropathy and Gabapentin · Diabetic neuropathy and Pregabalin · See more »

Drug tolerance

Drug tolerance is a pharmacological concept describing subjects' reduced reaction to a drug following its repeated use.

Drug tolerance and Gabapentin · Drug tolerance and Pregabalin · See more »

Drug withdrawal

Drug withdrawal is the group of symptoms that occur upon the abrupt discontinuation or decrease in intake of medications or recreational drugs.

Drug withdrawal and Gabapentin · Drug withdrawal and Pregabalin · See more »

Elimination (pharmacology)

In pharmacology the elimination or excretion of a drug is understood to be any one of a number of processes by which a drug is eliminated (that is, cleared and excreted) from an organism either in an unaltered form (unbound molecules) or modified as a metabolite.

Elimination (pharmacology) and Gabapentin · Elimination (pharmacology) and Pregabalin · See more »

Endogeny (biology)

Endogenous substances and processes are those that originate from within an organism, tissue, or cell.

Endogeny (biology) and Gabapentin · Endogeny (biology) and Pregabalin · See more »

Enzyme

Enzymes are macromolecular biological catalysts.

Enzyme and Gabapentin · Enzyme and Pregabalin · See more »

Epilepsy

Epilepsy is a group of neurological disorders characterized by epileptic seizures.

Epilepsy and Gabapentin · Epilepsy and Pregabalin · See more »

Epileptic seizure

An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.

Epileptic seizure and Gabapentin · Epileptic seizure and Pregabalin · See more »

Focal seizure

Focal seizures (also called partial seizures and localized seizures) are seizures which affect initially only one hemisphere of the brain.

Focal seizure and Gabapentin · Focal seizure and Pregabalin · See more »

Food and Drug Administration

The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.

Food and Drug Administration and Gabapentin · Food and Drug Administration and Pregabalin · See more »

GABA analogue

A GABA analogue is a compound which is an analogue or derivative of the neurotransmitter gamma-Aminobutyric acid (GABA) (the IUPAC of which is 4-aminobutanoic acid).

GABA analogue and Gabapentin · GABA analogue and Pregabalin · See more »

GABA receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system.

GABA receptor and Gabapentin · GABA receptor and Pregabalin · See more »

GABA receptor agonist

A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects.

GABA receptor agonist and Gabapentin · GABA receptor agonist and Pregabalin · See more »

Gabapentinoid

Gabapentinoids, also known as α2δ ligands, are a class of drugs that are derivatives of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) (i.e., GABA analogues) which block α2δ subunit-containing voltage-dependent calcium channels (VDCCs).

Gabapentin and Gabapentinoid · Gabapentinoid and Pregabalin · See more »

Gastrointestinal tract

The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.

Gabapentin and Gastrointestinal tract · Gastrointestinal tract and Pregabalin · See more »

Generic drug

A generic drug is a pharmaceutical drug that is equivalent to a brand-name product in dosage, strength, route of administration, quality, performance, and intended use, but does not carry the brand name.

Gabapentin and Generic drug · Generic drug and Pregabalin · See more »

IC50

The half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function.

Gabapentin and IC50 · IC50 and Pregabalin · See more »

In vivo

Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

Gabapentin and In vivo · In vivo and Pregabalin · See more »

Insomnia

Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping.

Gabapentin and Insomnia · Insomnia and Pregabalin · See more »

Isoleucine

Isoleucine (symbol Ile or I) is an α-amino acid that is used in the biosynthesis of proteins.

Gabapentin and Isoleucine · Isoleucine and Pregabalin · See more »

Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

Gabapentin and Kidney · Kidney and Pregabalin · See more »

Kidney failure

Kidney failure, also known as end-stage kidney disease, is a medical condition in which the kidneys no longer work.

Gabapentin and Kidney failure · Kidney failure and Pregabalin · See more »

Leucine

Leucine (symbol Leu or L) is an essential amino acid that is used in the biosynthesis of proteins.

Gabapentin and Leucine · Leucine and Pregabalin · See more »

Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

Gabapentin and Ligand (biochemistry) · Ligand (biochemistry) and Pregabalin · See more »

Lipophilicity

Lipophilicity (from Greek λίπος "fat" and φίλος "friendly"), refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene.

Gabapentin and Lipophilicity · Lipophilicity and Pregabalin · See more »

Low back pain

Low back pain (LBP) is a common disorder involving the muscles, nerves, and bones of the back.

Gabapentin and Low back pain · Low back pain and Pregabalin · See more »

Medicine

Medicine is the science and practice of the diagnosis, treatment, and prevention of disease.

Gabapentin and Medicine · Medicine and Pregabalin · See more »

Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.

Gabapentin and Metabolism · Metabolism and Pregabalin · See more »

Molar concentration

Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular of a solute in a solution, in terms of amount of substance per unit volume of solution.

Gabapentin and Molar concentration · Molar concentration and Pregabalin · See more »

Neuropathic pain

Neuropathic pain is pain caused by damage or disease affecting the somatosensory nervous system.

Gabapentin and Neuropathic pain · Neuropathic pain and Pregabalin · See more »

Neurotransmitter transporter

Neurotransmitter transporters are a class of membrane transport proteins that span the cellular membranes of neurons.

Gabapentin and Neurotransmitter transporter · Neurotransmitter transporter and Pregabalin · See more »

Obsessive–compulsive disorder

Obsessive–compulsive disorder (OCD) is a mental disorder where people feel the need to check things repeatedly, perform certain routines repeatedly (called "rituals"), or have certain thoughts repeatedly (called "obsessions").

Gabapentin and Obsessive–compulsive disorder · Obsessive–compulsive disorder and Pregabalin · See more »

Opioid

Opioids are substances that act on opioid receptors to produce morphine-like effects.

Gabapentin and Opioid · Opioid and Pregabalin · See more »

Oral administration

| name.

Gabapentin and Oral administration · Oral administration and Pregabalin · See more »

Parke-Davis

Parke-Davis is a subsidiary of the pharmaceutical company Pfizer.

Gabapentin and Parke-Davis · Parke-Davis and Pregabalin · See more »

Pfizer

Pfizer Inc. is an American pharmaceutical conglomerate headquartered in New York City, with its research headquarters in Groton, Connecticut.

Gabapentin and Pfizer · Pfizer and Pregabalin · See more »

Pharmacodynamics

Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).

Gabapentin and Pharmacodynamics · Pharmacodynamics and Pregabalin · See more »

Pharmacokinetics

Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism.

Gabapentin and Pharmacokinetics · Pharmacokinetics and Pregabalin · See more »

Phenylalanine

Phenylalanine (symbol Phe or F) is an α-amino acid with the formula.

Gabapentin and Phenylalanine · Phenylalanine and Pregabalin · See more »

Plasma protein binding

Plasma protein binding refers to the degree to which medications attach to proteins within the blood.

Gabapentin and Plasma protein binding · Plasma protein binding and Pregabalin · See more »

Postherpetic neuralgia

Postherpetic neuralgia (PHN) is nerve pain which occurs due to damage to a peripheral nerve caused by the reactivation of the varicella zoster virus (herpes zoster, also known as shingles).

Gabapentin and Postherpetic neuralgia · Postherpetic neuralgia and Pregabalin · See more »

Recreational drug use

Recreational drug use is the use of a psychoactive drug to induce an altered state of consciousness for pleasure, by modifying the perceptions, feelings, and emotions of the user.

Gabapentin and Recreational drug use · Pregabalin and Recreational drug use · See more »

Restless legs syndrome

Restless legs syndrome (RLS) is a disorder that causes a strong urge to move one's legs.

Gabapentin and Restless legs syndrome · Pregabalin and Restless legs syndrome · See more »

Saturation (chemistry)

In chemistry, saturation (from the Latin word saturare, meaning 'to fill') has diverse meanings, all based on the idea of reaching a maximum capacity.

Gabapentin and Saturation (chemistry) · Pregabalin and Saturation (chemistry) · See more »

Side effect

In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.

Gabapentin and Side effect · Pregabalin and Side effect · See more »

Somnolence

Somnolence (alternatively "sleepiness" or "drowsiness") is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia).

Gabapentin and Somnolence · Pregabalin and Somnolence · See more »

Structural analog

A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.

Gabapentin and Structural analog · Pregabalin and Structural analog · See more »

Substance abuse

Substance abuse, also known as drug abuse, is a patterned use of a drug in which the user consumes the substance in amounts or with methods which are harmful to themselves or others, and is a form of substance-related disorder.

Gabapentin and Substance abuse · Pregabalin and Substance abuse · See more »

The New York Times

The New York Times (sometimes abbreviated as The NYT or The Times) is an American newspaper based in New York City with worldwide influence and readership.

Gabapentin and The New York Times · Pregabalin and The New York Times · See more »

Urine

Urine is a liquid by-product of metabolism in humans and in many animals.

Gabapentin and Urine · Pregabalin and Urine · See more »

Venlafaxine

Venlafaxine, sold under the brand name Effexor among others, is an antidepressant of the selective serotonin-norepinephrine reuptake inhibitor (SNRI) class.

Gabapentin and Venlafaxine · Pregabalin and Venlafaxine · See more »

Voltage-gated calcium channel

Voltage-gated calcium channels (VGCCs), also known as voltage-dependent calcium channels (VDCCs), are a group of voltage-gated ion channels found in the membrane of excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the calcium ion Ca2+.

Gabapentin and Voltage-gated calcium channel · Pregabalin and Voltage-gated calcium channel · See more »

Warner–Lambert

Warner–Lambert was an American pharmaceutical company.

Gabapentin and Warner–Lambert · Pregabalin and Warner–Lambert · See more »

The list above answers the following questions

Gabapentin and Pregabalin Comparison

Gabapentin has 163 relations, while Pregabalin has 177. As they have in common 79, the Jaccard index is 23.24% = 79 / (163 + 177).

References

This article shows the relationship between Gabapentin and Pregabalin. To access each article from which the information was extracted, please visit:

Hey! We are on Facebook now! »