Table of Contents
29 relations: Advanced glycation end-product, Alagebrium, Alzheimer's disease, Amadori rearrangement, Cardiovascular disease, Cornea, Covalent bond, Crystallin, Cytotoxicity, Diabetes, DJ-1, DNA damage (naturally occurring), Fructose, Galactose, Glucose, Glycated hemoglobin, Glycosylation, Glyoxal, Guanine, Lens (vertebrate anatomy), Lipid, List of aging processes, Maillard reaction, Methylglyoxal, Mutation, Nucleic acid, Post-translational modification, Protein, Schiff base.
- Ageing processes
Advanced glycation end-product
Advanced glycation end products (AGEs) are proteins or lipids that become glycated as a result of exposure to sugars. Glycation and Advanced glycation end-product are post-translational modification.
See Glycation and Advanced glycation end-product
Alagebrium
Alagebrium (formerly known as ALT-711, dimethyl-3-N-phenacylthiazolium chloride) was a drug candidate developed by Alteon, Inc. Glycation and Alagebrium are post-translational modification.
Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, and is the cause of 60–70% of cases of dementia.
See Glycation and Alzheimer's disease
Amadori rearrangement
The Amadori rearrangement is an organic reaction describing the acid or base catalyzed isomerization or rearrangement reaction of the N-glycoside of an aldose or the glycosylamine to the corresponding 1-amino-1-deoxy-ketose. Glycation and Amadori rearrangement are post-translational modification.
See Glycation and Amadori rearrangement
Cardiovascular disease
Cardiovascular disease (CVD) is any disease involving the heart or blood vessels.
See Glycation and Cardiovascular disease
Cornea
The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber.
Covalent bond
A covalent bond is a chemical bond that involves the sharing of electrons to form electron pairs between atoms.
See Glycation and Covalent bond
Crystallin
In anatomy, a crystallin is a water-soluble structural protein found in the lens and the cornea of the eye accounting for the transparency of the structure.
Cytotoxicity
Cytotoxicity is the quality of being toxic to cells.
See Glycation and Cytotoxicity
Diabetes
Diabetes mellitus, often known simply as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels.
DJ-1
Protein deglycase DJ-1, also known as Parkinson disease protein 7, is a protein which in humans is encoded by the PARK7 gene.
DNA damage (naturally occurring)
DNA damage is an alteration in the chemical structure of DNA, such as a break in a strand of DNA, a nucleobase missing from the backbone of DNA, or a chemically changed base such as 8-OHdG.
See Glycation and DNA damage (naturally occurring)
Fructose
Fructose, or fruit sugar, is a ketonic simple sugar found in many plants, where it is often bonded to glucose to form the disaccharide sucrose.
Galactose
Galactose (galacto- + -ose, "milk sugar"), sometimes abbreviated Gal, is a monosaccharide sugar that is about as sweet as glucose, and about 65% as sweet as sucrose.
Glucose
Glucose is a sugar with the molecular formula.
Glycated hemoglobin
Glycated hemoglobin, glycohemoglobin, glycosylated hemoglobin is a form of hemoglobin (Hb) that is chemically linked to a sugar.
See Glycation and Glycated hemoglobin
Glycosylation
Glycosylation is the reaction in which a carbohydrate (or 'glycan'), i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor) in order to form a glycoconjugate. Glycation and Glycosylation are carbohydrates and post-translational modification.
See Glycation and Glycosylation
Glyoxal
Glyoxal is an organic compound with the chemical formula OCHCHO.
Guanine
Guanine (symbol G or Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA).
Lens (vertebrate anatomy)
The lens, or crystalline lens, is a transparent biconvex structure in most land vertebrate eyes.
See Glycation and Lens (vertebrate anatomy)
Lipid
Lipids are a broad group of organic compounds which include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others.
List of aging processes
* Accumulation of lipofuscin. Glycation and List of aging processes are Ageing processes.
See Glycation and List of aging processes
Maillard reaction
The Maillard reaction is a chemical reaction between amino acids and reducing sugars to create melanoidins, the compounds which give browned food its distinctive flavor.
See Glycation and Maillard reaction
Methylglyoxal
Methylglyoxal (MGO) is the organic compound with the formula CH3C(O)CHO.
See Glycation and Methylglyoxal
Mutation
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA.
Nucleic acid
Nucleic acids are large biomolecules that are crucial in all cells and viruses.
See Glycation and Nucleic acid
Post-translational modification
In molecular biology, post-translational modification (PTM) is the covalent process of changing proteins following protein biosynthesis.
See Glycation and Post-translational modification
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.
Schiff base
In organic chemistry, a Schiff base (named after Hugo Schiff) is a compound with the general structure (.
See also
Ageing processes
- Age of onset
- Cellular senescence
- Cross-link
- Degenerative disease
- Dog Aging Project
- Glycation
- Immunosenescence
- List of aging processes
- Thymic involution
References
Also known as Glycate, Non-enzymatic glycosylation.