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Glycine receptor

Index Glycine receptor

The glycine receptor (abbreviated as GlyR or GLR) is the receptor of the amino acid neurotransmitter glycine. [1]

50 relations: African clawed frog, Alanine, Alpha helix, Amino acid, Bicuculline, Brainstem, Brucine, Caffeine, Central nervous system, Dorsal root ganglion, Ethanol, GABAA receptor, Gephyrin, GLRA2, GLRA3, GLRA4, GLRB, Glycine, Glycine receptor, alpha 1, Heterologous, Hippocampus, Hyperekplexia, Hypotaurine, Immortalised cell line, Inhibitory postsynaptic potential, Β-Alanine, Levorphanol, Ligand, Ligand-gated ion channel, Milacemide, Neuron, Neurotransmitter, Oocyte, Pentamer, Pharmacodynamics, Pharmacokinetics, Picrotoxin, Proline, Protein subunit, Quisqualamine, Receptor (biochemistry), Sarcosine, Serine, Spinal cord, Stiff-person syndrome, Strychnine, Taurine, Tetrahydrocannabinol, Transmembrane protein, Tutin (toxin).

African clawed frog

The African clawed frog (Xenopus laevis, also known as the xenopus, African clawed toad, African claw-toed frog or the platanna) is a species of African aquatic frog of the family Pipidae.

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Alanine

Alanine (symbol Ala or A) is an α-amino acid that is used in the biosynthesis of proteins.

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Alpha helix

The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.

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Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

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Bicuculline

Bicuculline is a phthalide-isoquinoline compound that is a light-sensitive competitive antagonist of GABAA receptors.

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Brainstem

The brainstem (or brain stem) is the posterior part of the brain, adjoining and structurally continuous with the spinal cord.

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Brucine

Brucine, an alkaloid closely related to strychnine, is most commonly found in the Strychnos nux-vomica tree.

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Caffeine

Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class.

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Dorsal root ganglion

A dorsal root ganglion (or spinal ganglion) (also known as a posterior root ganglion), is a cluster of neurons (a ganglion) in a dorsal root of a spinal nerve.

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Ethanol

Ethanol, also called alcohol, ethyl alcohol, grain alcohol, and drinking alcohol, is a chemical compound, a simple alcohol with the chemical formula.

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GABAA receptor

The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.

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Gephyrin

Gephyrin is a protein that in humans is encoded by the GPHN gene.

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GLRA2

Glycine receptor subunit alpha-2 is a protein that in humans is encoded by the GLRA2 gene.

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GLRA3

The Glycine receptor subunit alpha-3 is a protein that in humans is encoded by the GLRA3 gene.

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GLRA4

The glycine receptor, alpha 4, also known as GLRA4, is a human pseudogene.

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GLRB

Glycine receptor subunit beta is a protein that in humans is encoded by the GLRB gene.

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Glycine

Glycine (symbol Gly or G) is the amino acid that has a single hydrogen atom as its side chain.

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Glycine receptor, alpha 1

Glycine receptor subunit alpha-1 is a protein that in humans is encoded by the GLRA1 gene.

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Heterologous

In medicine a heterologous transplant means 'between species' or 'from one species to another'.

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Hippocampus

The hippocampus (named after its resemblance to the seahorse, from the Greek ἱππόκαμπος, "seahorse" from ἵππος hippos, "horse" and κάμπος kampos, "sea monster") is a major component of the brains of humans and other vertebrates.

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Hyperekplexia

Hyperekplexia ("exaggerated surprise") is a neurologic disorder classically characterised by pronounced startle responses to tactile or acoustic stimuli and hypertonia.

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Hypotaurine

Hypotaurine is a sulfinic acid that is an intermediate in the biosynthesis of taurine.

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Immortalised cell line

An immortalized cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division.

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Inhibitory postsynaptic potential

An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential.

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Β-Alanine

β-Alanine (or beta-alanine) is a naturally occurring beta amino acid, which is an amino acid in which the amino group is at the β-position from the carboxylate group (i.e., two atoms away, see Figure 1).

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Levorphanol

Levorphanol (INN; brand name Levo-Dromoran) is an opioid medication used to treat moderate to severe pain.

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Ligand

In coordination chemistry, a ligand is an ion or molecule (functional group) that binds to a central metal atom to form a coordination complex.

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Ligand-gated ion channel

Ligand-gated ion channels (LICs, LGIC), also commonly referred as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow ions such as Na+, K+, Ca2+, and/or Cl− to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand), such as a neurotransmitter.

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Milacemide

Milacemide (INN) is an MAO-B inhibitor and glycine prodrug.

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Neuron

A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.

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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission.

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Oocyte

An oocyte, oöcyte, ovocyte, or rarely ocyte, is a female gametocyte or germ cell involved in reproduction.

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Pentamer

A pentamer is an entity composed of five sub-units.

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Pharmacodynamics

Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).

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Pharmacokinetics

Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism.

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Picrotoxin

Picrotoxin, also known as cocculin, is a poisonous crystalline plant compound.

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Proline

Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins.

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Protein subunit

In structural biology, a protein subunit is a single protein molecule that assembles (or "coassembles") with other protein molecules to form a protein complex.

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Quisqualamine

Quisqualamine is the α-decarboxylated analogue of quisqualic acid, as well as a relative of the neurotransmitters glutamate and γ-aminobutyric acid (GABA).

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Receptor (biochemistry)

In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.

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Sarcosine

Sarcosine, also known as N-methylglycine, is an intermediate and byproduct in glycine synthesis and degradation.

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Serine

Serine (symbol Ser or S) is an ɑ-amino acid that is used in the biosynthesis of proteins.

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Spinal cord

The spinal cord is a long, thin, tubular bundle of nervous tissue and support cells that extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column.

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Stiff-person syndrome

Stiff-person syndrome (SPS), also known as stiff-man syndrome (SMS), is a rare neurologic disorder of unclear cause characterized by progressive rigidity and stiffness.

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Strychnine

Strychnine (also or) is a highly toxic, colorless, bitter, crystalline alkaloid used as a pesticide, particularly for killing small vertebrates such as birds and rodents.

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Taurine

No description.

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Tetrahydrocannabinol

Tetrahydrocannabinol (THC) is one of at least 113 cannabinoids identified in cannabis.

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Transmembrane protein

A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached.

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Tutin (toxin)

Tutin is a poisonous plant derivative found in the New Zealand tutu plant (genus Coriaria, several different species).

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Glycine receptors, Glycinergics, Receptors, glycine.

References

[1] https://en.wikipedia.org/wiki/Glycine_receptor

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