Monoamine transporter and Paroxetine

Shortcuts: Differences, Similarities, Jaccard Similarity Coefficient, References.

Difference between Monoamine transporter and Paroxetine

Monoamine transporter vs. Paroxetine

Monoamine transporters (MATs) are protein structures that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters. Paroxetine, also known by trade names including Paxil and Seroxat among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive-compulsive disorder, social anxiety disorder, panic disorder, posttraumatic stress disorder, generalized anxiety disorder and premenstrual dysphoric disorder. It has also been used in the treatment of hot flashes and night sweats associated with menopause. It has a similar tolerability profile to other SSRIs. The common side effects include drowsiness, dry mouth, loss of appetite, sweating, trouble sleeping and delayed ejaculation. It may also be associated with a slightly increased risk of birth defects. The rate of withdrawal symptoms in young people may be higher with paroxetine and venlafaxine than other SSRIs and SNRIs. Several studies have associated paroxetine with suicidal thinking and behavior in children and adolescents. Marketing of the drug began in 1992 by the pharmaceutical company SmithKline Beecham, known since 2000 as GlaxoSmithKline. Generic formulations have been available since 2003 when the patent expired. The United States Department of Justice fined GlaxoSmithKline $3 billion in 2012, including a sum for withholding data on paroxetine, unlawfully promoting it for under-18s and preparing an article, following one of its clinical trials, study 329, that misleadingly reported the drug was effective in treating adolescent depression.

Similarities between Monoamine transporter and Paroxetine

Monoamine transporter and Paroxetine have 9 things in common (in Unionpedia): Dopamine transporter, Fluoxetine, Major depressive disorder, Norepinephrine, Norepinephrine transporter, Selective serotonin reuptake inhibitor, Serotonin, Serotonin transporter, Venlafaxine.

Dopamine transporter

The dopamine transporter (also dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into cytosol.

Dopamine transporter and Monoamine transporter · Dopamine transporter and Paroxetine · See more »

Fluoxetine

Fluoxetine, also known by trade names Prozac and Sarafem, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

Fluoxetine and Monoamine transporter · Fluoxetine and Paroxetine · See more »

Major depressive disorder

Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.

Major depressive disorder and Monoamine transporter · Major depressive disorder and Paroxetine · See more »

Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.

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Norepinephrine transporter

The norepinephrine transporter (NET), also known as solute carrier family 6 member 2 (SLC6A2), is a protein that in humans is encoded by the SLC6A2 gene.

Monoamine transporter and Norepinephrine transporter · Norepinephrine transporter and Paroxetine · See more »

Selective serotonin reuptake inhibitor

Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.

Monoamine transporter and Selective serotonin reuptake inhibitor · Paroxetine and Selective serotonin reuptake inhibitor · See more »

Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

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Serotonin transporter

The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene.

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Venlafaxine

Venlafaxine, sold under the brand name Effexor among others, is an antidepressant of the selective serotonin-norepinephrine reuptake inhibitor (SNRI) class.

Monoamine transporter and Venlafaxine · Paroxetine and Venlafaxine · See more »

The list above answers the following questions

What Monoamine transporter and Paroxetine have in common
What are the similarities between Monoamine transporter and Paroxetine

Monoamine transporter and Paroxetine Comparison

Monoamine transporter has 86 relations, while Paroxetine has 102. As they have in common 9, the Jaccard index is 4.79% = 9 / (86 + 102).

References

This article shows the relationship between Monoamine transporter and Paroxetine. To access each article from which the information was extracted, please visit:

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