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NMDA receptor and Rislenemdaz

Shortcuts: Differences, Similarities, Jaccard Similarity Coefficient, References.

Difference between NMDA receptor and Rislenemdaz

NMDA receptor vs. Rislenemdaz

The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and ion channel protein found in nerve cells. Rislenemdaz (developmental code names CERC-301, MK-0657) is an orally-active, selective NMDA receptor subunit 2B (NR2B) antagonist which is under development by Cerecor in the United States as an adjunctive therapy for treatment-resistant depression (TRD).

Similarities between NMDA receptor and Rislenemdaz

NMDA receptor and Rislenemdaz have 13 things in common (in Unionpedia): Apimostinel, Clinical trial, Efficacy, Glutamic acid, GRIN2B, Ketamine, Major depressive disorder, NMDA receptor, Receptor antagonist, Traxoprodil, Treatment-resistant depression, United States, 4-Chlorokynurenine.

Apimostinel

Apimostinel (former developmental code name NRX-1074) is an antidepressant, acting as a selective partial agonist of an allosteric site of the glycine site of the NMDA receptor complex, which is under investigation by Naurex and Allergan for the treatment of major depressive disorder (MDD).

Apimostinel and NMDA receptor · Apimostinel and Rislenemdaz · See more »

Clinical trial

Clinical trials are experiments or observations done in clinical research.

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Efficacy

Efficacy is the ability to get a job done satisfactorily.

Efficacy and NMDA receptor · Efficacy and Rislenemdaz · See more »

Glutamic acid

Glutamic acid (symbol Glu or E) is an α-amino acid with formula.

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GRIN2B

Glutamate receptor subunit epsilon-2, also known as N-methyl D-aspartate receptor subtype 2B (NMDAR2B or NR2B), is a protein that in humans is encoded by the GRIN2B gene.

GRIN2B and NMDA receptor · GRIN2B and Rislenemdaz · See more »

Ketamine

Ketamine, sold under the brand name Ketalar among others, is a medication mainly used for starting and maintaining anesthesia.

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Major depressive disorder

Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.

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NMDA receptor

The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and ion channel protein found in nerve cells.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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Traxoprodil

Traxoprodil (developmental code name CP-101606) is a drug developed by Pfizer which acts as an NMDA antagonist, selective for the NR2B subunit.

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Treatment-resistant depression

Treatment-resistant depression (TRD) or treatment-refractory depression is a term used in clinical psychiatry to describe cases of major depressive disorder (MDD) that do not respond adequately to appropriate courses of at least two antidepressants.

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United States

The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.

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4-Chlorokynurenine

L-4-Chlorokynurenine (4-Cl-KYN; developmental code name AV-101) is an orally active small molecule prodrug of 7-chlorokynurenic acid, a NMDA receptor antagonist.

4-Chlorokynurenine and NMDA receptor · 4-Chlorokynurenine and Rislenemdaz · See more »

The list above answers the following questions

NMDA receptor and Rislenemdaz Comparison

NMDA receptor has 238 relations, while Rislenemdaz has 24. As they have in common 13, the Jaccard index is 4.96% = 13 / (238 + 24).

References

This article shows the relationship between NMDA receptor and Rislenemdaz. To access each article from which the information was extracted, please visit:

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