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Neuromedin U receptor

Index Neuromedin U receptor

The neuromedin U receptors are two G-protein coupled receptors which bind the neuropeptide hormones neuromedin U and neuromedin S. There are two subtypes of the neuromedin U receptor, each encoded by a separate gene. [1]

6 relations: G protein–coupled receptor, Neuromedin S, Neuromedin U, Neuromedin U receptor 1, Neuromedin U receptor 2, Pharmacological Reviews.

G protein–coupled receptor

G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.

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Neuromedin S

Neuromedin S is a 36-amino acid neuropeptide found in the brain of humans and other mammals.

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Neuromedin U

Neuromedin U (or NmU) is a neuropeptide found in the brain of humans and other mammals, which has a number of diverse functions including contraction of smooth muscle, regulation of blood pressure, pain perception, appetite, bone growth, and hormone release.

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Neuromedin U receptor 1

Neuromedin-U receptor 1 is a protein that in humans is encoded by the NMUR1 gene.

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Neuromedin U receptor 2

Neuromedin-U receptor 2 is a protein that in humans is encoded by the NMUR2 gene.

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Pharmacological Reviews

Pharmacological Reviews is a quarterly peer-reviewed scientific journal publishing review articles on all aspects of pharmacology and related topics.

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References

[1] https://en.wikipedia.org/wiki/Neuromedin_U_receptor

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