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Oxycodone and Pharmacogenomics

Shortcuts: Differences, Similarities, Jaccard Similarity Coefficient, References.

Difference between Oxycodone and Pharmacogenomics

Oxycodone vs. Pharmacogenomics

Oxycodone, sold under brand names such as Percocet and OxyContin among many others, is an opioid medication which is used for the relief of moderate to severe pain. Pharmacogenomics is the study of the role of the genome in drug response.

Similarities between Oxycodone and Pharmacogenomics

Oxycodone and Pharmacogenomics have 9 things in common (in Unionpedia): Biological target, Clearance (pharmacology), Codeine, CYP2D6, CYP3A4, Cytochrome P450, Food and Drug Administration, Genotype, Metabolism.

Biological target

A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.

Biological target and Oxycodone · Biological target and Pharmacogenomics · See more »

Clearance (pharmacology)

In pharmacology, the clearance is a pharmacokinetic measurement of the volume of plasma from which a substance is completely removed per unit time; the usual units are mL/min.

Clearance (pharmacology) and Oxycodone · Clearance (pharmacology) and Pharmacogenomics · See more »

Codeine

Codeine is an opiate used to treat pain, as a cough medicine, and for diarrhea. It is typically used to treat mild to moderate degrees of pain. Greater benefit may occur when combined with paracetamol (acetaminophen) or a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin or ibuprofen. Evidence does not support its use for acute cough suppression in children or adults. In Europe it is not recommended as a cough medicine in those under twelve years of age. It is generally taken by mouth. It typically starts working after half an hour with maximum effect at two hours. The total duration of its effects last for about four to six hours. Common side effects include vomiting, constipation, itchiness, lightheadedness, and drowsiness. Serious side effects may include breathing difficulties and addiction. It is unclear if its use in pregnancy is safe. Care should be used during breastfeeding as it may result in opiate toxicity in the baby. Its use as of 2016 is not recommended in children. Codeine works following being broken down by the liver into morphine. How quickly this occurs depends on a person's genetics. Codeine was discovered in 1832 by Pierre Jean Robiquet. In 2013 about 361,000 kilograms of codeine were produced while 249,000 kilograms were used. This makes it the most commonly taken opiate. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is between 0.04 and 0.29 USD per dose as of 2014. In the United States it costs about one dollar a dose. Codeine occurs naturally and makes up about 2% of opium.

Codeine and Oxycodone · Codeine and Pharmacogenomics · See more »

CYP2D6

Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene.

CYP2D6 and Oxycodone · CYP2D6 and Pharmacogenomics · See more »

CYP3A4

Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.

CYP3A4 and Oxycodone · CYP3A4 and Pharmacogenomics · See more »

Cytochrome P450

Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.

Cytochrome P450 and Oxycodone · Cytochrome P450 and Pharmacogenomics · See more »

Food and Drug Administration

The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.

Food and Drug Administration and Oxycodone · Food and Drug Administration and Pharmacogenomics · See more »

Genotype

The genotype is the part of the genetic makeup of a cell, and therefore of an organism or individual, which determines one of its characteristics (phenotype).

Genotype and Oxycodone · Genotype and Pharmacogenomics · See more »

Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.

Metabolism and Oxycodone · Metabolism and Pharmacogenomics · See more »

The list above answers the following questions

Oxycodone and Pharmacogenomics Comparison

Oxycodone has 213 relations, while Pharmacogenomics has 95. As they have in common 9, the Jaccard index is 2.92% = 9 / (213 + 95).

References

This article shows the relationship between Oxycodone and Pharmacogenomics. To access each article from which the information was extracted, please visit:

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