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Paroxetine and Selective serotonin reuptake inhibitor

Shortcuts: Differences, Similarities, Jaccard Similarity Coefficient, References.

Difference between Paroxetine and Selective serotonin reuptake inhibitor

Paroxetine vs. Selective serotonin reuptake inhibitor

Paroxetine, also known by trade names including Paxil and Seroxat among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive-compulsive disorder, social anxiety disorder, panic disorder, posttraumatic stress disorder, generalized anxiety disorder and premenstrual dysphoric disorder. It has also been used in the treatment of hot flashes and night sweats associated with menopause. It has a similar tolerability profile to other SSRIs. The common side effects include drowsiness, dry mouth, loss of appetite, sweating, trouble sleeping and delayed ejaculation. It may also be associated with a slightly increased risk of birth defects. The rate of withdrawal symptoms in young people may be higher with paroxetine and venlafaxine than other SSRIs and SNRIs. Several studies have associated paroxetine with suicidal thinking and behavior in children and adolescents. Marketing of the drug began in 1992 by the pharmaceutical company SmithKline Beecham, known since 2000 as GlaxoSmithKline. Generic formulations have been available since 2003 when the patent expired. The United States Department of Justice fined GlaxoSmithKline $3 billion in 2012, including a sum for withholding data on paroxetine, unlawfully promoting it for under-18s and preparing an article, following one of its clinical trials, study 329, that misleadingly reported the drug was effective in treating adolescent depression. Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.

Similarities between Paroxetine and Selective serotonin reuptake inhibitor

Paroxetine and Selective serotonin reuptake inhibitor have 34 things in common (in Unionpedia): Anorgasmia, Antidepressant, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP3A4, Cytochrome P450, Dopamine transporter, Epileptic seizure, Erectile dysfunction, Escitalopram, Fluoxetine, Food and Drug Administration, Generalized anxiety disorder, Major depressive disorder, Monoamine oxidase inhibitor, Norepinephrine transporter, Obsessive–compulsive disorder, Panic disorder, Posttraumatic stress disorder, Serotonin, Serotonin syndrome, Serotonin transporter, Sertraline, Social anxiety disorder, Tachycardia, Triptan, Venlafaxine, ..., Warfarin, 5-HT1A receptor, 5-HT2A receptor, 5-HT3 receptor. Expand index (4 more) »

Anorgasmia

Anorgasmia, or Coughlan's syndrome, is a type of sexual dysfunction in which a person cannot achieve orgasm despite adequate stimulation.

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Antidepressant

Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.

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CYP1A2

Cytochrome P450 1A2 (abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body.

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CYP2B6

Cytochrome P450 2B6 is an enzyme that in humans is encoded by the CYP2B6 gene.

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CYP2C19

Cytochrome P450 2C19 (abbreviated CYP2C19) is an enzyme.

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CYP2C9

Cytochrome P450 2C9 (abbreviated CYP2C9) is an enzyme that in humans is encoded by the CYP2C9 gene.

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CYP2D6

Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene.

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CYP3A4

Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.

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Cytochrome P450

Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.

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Dopamine transporter

The dopamine transporter (also dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into cytosol.

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Epileptic seizure

An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.

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Erectile dysfunction

Erectile dysfunction (ED), also known as impotence, is a type of sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity.

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Escitalopram

Escitalopram, sold under the brand names Cipralex and Lexapro among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

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Fluoxetine

Fluoxetine, also known by trade names Prozac and Sarafem, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

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Food and Drug Administration

The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.

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Generalized anxiety disorder

Generalized anxiety disorder (GAD) is an anxiety disorder characterized by excessive, uncontrollable and often irrational worry, that is, apprehensive expectation about events or activities.

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Major depressive disorder

Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.

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Monoamine oxidase inhibitor

Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B).

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Norepinephrine transporter

The norepinephrine transporter (NET), also known as solute carrier family 6 member 2 (SLC6A2), is a protein that in humans is encoded by the SLC6A2 gene.

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Obsessive–compulsive disorder

Obsessive–compulsive disorder (OCD) is a mental disorder where people feel the need to check things repeatedly, perform certain routines repeatedly (called "rituals"), or have certain thoughts repeatedly (called "obsessions").

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Panic disorder

Panic disorder is an anxiety disorder characterized by reoccurring unexpected panic attacks.

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Posttraumatic stress disorder

Posttraumatic stress disorder (PTSD)Acceptable variants of this term exist; see the Terminology section in this article.

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Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

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Serotonin syndrome

Serotonin syndrome (SS) is a group of symptoms that may occur following use of certain serotonergic medications or drugs.

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Serotonin transporter

The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene.

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Sertraline

Sertraline, sold under the trade names Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

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Social anxiety disorder

Social anxiety disorder (SAD), also known as social phobia, is an anxiety disorder characterized by a significant amount of fear in one or more social situations, causing considerable distress and impaired ability to function in at least some parts of daily life.

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Tachycardia

Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate.

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Triptan

Triptans are a family of tryptamine-based drugs used as abortive medication in the treatment of migraines and cluster headaches.

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Venlafaxine

Venlafaxine, sold under the brand name Effexor among others, is an antidepressant of the selective serotonin-norepinephrine reuptake inhibitor (SNRI) class.

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Warfarin

Warfarin, sold under the brand name Coumadin among others, is a medication that is used as an anticoagulant (blood thinner).

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5-HT1A receptor

The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptor (5-HT receptor) that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

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5-HT2A receptor

The mammalian 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR).

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5-HT3 receptor

The 5-HT3 receptor belongs to the Cys-loop superfamily of ligand-gated ion channels (LGICs) and therefore differs structurally and functionally from all other 5-HT receptors (5-hydroxytryptamine, or serotonin) receptors which are G protein-coupled receptors.

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The list above answers the following questions

Paroxetine and Selective serotonin reuptake inhibitor Comparison

Paroxetine has 102 relations, while Selective serotonin reuptake inhibitor has 206. As they have in common 34, the Jaccard index is 11.04% = 34 / (102 + 206).

References

This article shows the relationship between Paroxetine and Selective serotonin reuptake inhibitor. To access each article from which the information was extracted, please visit:

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