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24 relations: Act, Axicabtagene ciloleucel, Cancer, Cancer immunotherapy, Checkpoint inhibitor, Chimeric antigen receptor, Diffuse large B-cell lymphoma, Donor lymphocyte infusion, Epithelioid sarcoma, Gene therapy, Immunotherapy, IMP321, Ipilimumab, Mantle cell lymphoma, Melanoma, Nicholas P. Restifo, Outline of immunology, Steven Rosenberg, Synthetic immunology, Timeline of melanoma, Tisagenlecleucel, Tumor microenvironment, Tumor-infiltrating lymphocytes, Zelig Eshhar.
Act
Act or ACT may refer to.
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Axicabtagene ciloleucel
Axicabtagene ciloleucel (KTE-C19, Axi-cel), marketed as Yescarta, is an adoptive cell transfer therapy for treating certain cases of large B-cell lymphoma.
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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Cancer immunotherapy
Cancer immunotherapy (sometimes called immuno-oncology, abbreviated IO) is the use of the immune system to treat cancer.
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Checkpoint inhibitor
Checkpoint inhibitor therapy is a form of cancer treatment immunotherapy currently under research.
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Chimeric antigen receptor
Chimeric antigen receptors (CARs, also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors) are engineered receptors that combine a new specificity with an immune cell to target cancer cells.
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Diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma (DLBCL or DLBL) is a cancer of B cells, a type of white blood cell responsible for producing antibodies.
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Donor lymphocyte infusion
Donor lymphocyte (or leukocyte) infusion (DLI) or buffy coat infusion is a form of adoptive immunotherapy used after hematopoietic stem cell transplantation.
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Epithelioid sarcoma
Epithelioid sarcoma is a rare soft tissue sarcoma arising from mesenchymal tissue and characterized by epithelioid-like features.
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Gene therapy
In the medicine field, gene therapy (also called human gene transfer) is the therapeutic delivery of nucleic acid into a patient's cells as a drug to treat disease.
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Immunotherapy
Immunotherapy is the "treatment of disease by inducing, enhancing, or suppressing an immune response".
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IMP321
IMP321 is a large molecule cancer drug being developed by the clinical stage biotechnology company Prima BioMed (Nasdaq: IMMP).
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Ipilimumab
Ipilimumab (trade name Yervoy) is a monoclonal antibody that works to activate the immune system by targeting CTLA-4, a protein receptor that downregulates the immune system.
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Mantle cell lymphoma
Mantle cell lymphoma (MCL) is a type of non-Hodgkin's lymphoma (NHL), comprising about 6% of NHL cases.
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Melanoma
Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes.
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Nicholas P. Restifo
Nicholas P. Restifo (born July 24, 1960) is an American immunologist, physician and educator in cancer immunotherapy.
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Outline of immunology
The following outline is provided as an overview of and topical guide to immunology: Immunology is the study of all aspects of the immune system in all organisms.
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Steven Rosenberg
Steven A. Rosenberg (born 2 August 1940) is an American cancer researcher and surgeon, chief of Surgery at the National Cancer Institute in Bethesda, Maryland and a Professor of Surgery at the Uniformed Services University of Health Sciences and the George Washington University School of Medicine and Health Sciences.
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Synthetic immunology
Synthetic immunology is the rational design and construction of synthetic systems that perform complex immunological functions.
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Timeline of melanoma
This is a timeline of melanoma, describing especially major discoveries and advances in treatment against the disease.
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Tisagenlecleucel
Tisagenlecleucel, marketed as Kymriah, is a treatment for B-cell acute lymphoblastic leukemia which uses the body's own T cells to fight cancer (adoptive cell transfer).
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Tumor microenvironment
The tumor microenvironment (TME) is the cellular environment in which the tumor exists, including surrounding blood vessels, immune cells, fibroblasts, bone marrow-derived inflammatory cells, lymphocytes, signaling molecules and the extracellular matrix (ECM).
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Tumor-infiltrating lymphocytes
Tumor-infiltrating lymphocytes are white blood cells that have left the bloodstream and migrated toward tumor.
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Zelig Eshhar
Zelig Eshhar is an Israeli immunologist at the Weizmann Institute of Science and the Tel Aviv Sourasky Medical Center.
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Adoptive cell therapy, Adoptive immunotherapy, Cancer Fighting Cells, Cell transfer, Intrinsic checkpoint blockade.
References
[1] https://en.wikipedia.org/wiki/Adoptive_cell_transfer
