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Alpha-1A adrenergic receptor

Index Alpha-1A adrenergic receptor

The alpha-1A adrenergic receptor (α1A adrenoreceptor), also known as ADRA1A, formerly known also as the alpha-1C adrenergic receptor, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it. [1]

48 relations: Adrenergic receptor, Alpha-2 adrenergic receptor, Amisulpride, Amitriptyline/perphenazine, Apomorphine, Aripiprazole, Brexpiprazole, Bromocriptine, Cabergoline, Cariprazine, Chloroethylclonidine, Cirazoline, Clonidine, Clorotepine, Clozapine, Haloperidol, List of investigational antidepressants, Loxapine, Lumateperone, Meta-Chlorophenylpiperazine, MIN-117, Mirtazapine, Nefazodone, Nicergoline, Olanzapine, Paliperidone, Perphenazine, Pimozide, Quetiapine, Raymond P. Ahlquist, Reboxetine, Rhodopsin-like receptors, Risperidone, Rotigotine, Sertindole, Silodosin, Spiperone, Tamsulosin, Tedatioxetine, Thioridazine, Tianeptine, Tiotixene, Trazodone, Yohimbine, Ziprasidone, Zotepine, 1A, 5'-Guanidinonaltrindole.

Adrenergic receptor

The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline).

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Alpha-2 adrenergic receptor

The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein.

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Amisulpride

Amisulpride, sold under the brand name Solian among others, is an antipsychotic medication used to treat schizophrenia.

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Amitriptyline/perphenazine

Amitriptyline/perphenazine (Duo-Vil, Etrafon, Triavil, Triptafen) is a formulation that contains the tricyclic antidepressant amitriptyline and the medium-potency typical (first-generation) antipsychotic, perphenazine.

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Apomorphine

Apomorphine (brand names Apokyn, Ixense, Spontane, Uprima) is a type of aporphine having activity as a non-selective dopamine agonist which activates both D2-like and, to a much lesser extent, D1-like receptors.

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Aripiprazole

Aripiprazole, sold under the brand name Abilify among others, is an atypical antipsychotic. It is recommended and primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders, and irritability associated with autism. According to a Cochrane review, evidence for the oral form in schizophrenia is not sufficient to determine effects on general functioning. Additionally, because many people dropped out of the medication trials before they were completed, the overall strength of the conclusions is low. Side effects include neuroleptic malignant syndrome, a movement disorder known as tardive dyskinesia, and high blood sugar in those with diabetes. In the elderly there is an increased risk of death. It is thus not recommended for use in those with psychosis due to dementia. It is pregnancy category C in the United States and category C in Australia, meaning there is possible evidence of harm to the fetus. It is not recommended for women who are breastfeeding. It is unclear whether it is safe or effective in people less than 18 years old. It is a partial dopamine agonist. Aripiprazole was developed by Otsuka in Japan. In the United States, Otsuka America markets it jointly with Bristol-Myers Squibb. From April 2013 to March 2014, sales of Abilify amounted to almost $6.9 billion.

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Brexpiprazole

Brexpiprazole, sold under the brand name Rexulti, is an atypical antipsychotic.

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Bromocriptine

Bromocriptine (originally marketed as Parlodel, subsequently under many names) is an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.

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Cabergoline

Cabergoline (brand names Dostinex and others), an ergot derivative, is a potent dopamine receptor agonist on D2 receptors.

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Cariprazine

Cariprazine, sold under the brand names Vraylar in the United States and Reagila in Europe, is an atypical antipsychotic which is used in the treatment of schizophrenia and bipolar mania.

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Chloroethylclonidine

Chloroethylclonidine is an irreversible agonist for adrenergic receptors, in particular alpha1B, D, C and alpha2A/D-subtypes.

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Cirazoline

Cirazoline is a full agonist at the α1A adrenergic receptor, a partial agonist at both the α1B and α1D adrenergic receptors, and a nonselective antagonist to the α2 adrenergic receptor.

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Clonidine

Clonidine (trade names Catapres, Kapvay, Nexiclon, Clophelin, and others) is a medication used to treat high blood pressure, attention deficit hyperactivity disorder, anxiety disorders, tic disorders, withdrawal (from either alcohol, opioids, or smoking), migraine, menopausal flushing, diarrhea, and certain pain conditions.

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Clorotepine

Clorotepine (brand names Clotepin, Clopiben), also known as octoclothepin or octoclothepine, is an antipsychotic of the tricyclic group which was derived from perathiepin in 1965 and marketed in the Czech Republic by Spofa in or around 1971 for the treatment of schizophrenic psychosis.

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Clozapine

Clozapine, sold under the brand name Clozaril among others, is an atypical antipsychotic medication.

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Haloperidol

Haloperidol, marketed under the trade name Haldol among others, is a typical antipsychotic medication.

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List of investigational antidepressants

This is a list of investigational antidepressants, or antidepressants that are currently under development for clinical use in the treatment of mood disorders but are not yet approved.

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Loxapine

Loxapine (several trade names worldwide) is a typical antipsychotic medication, used primarily in the treatment of schizophrenia.

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Lumateperone

Lumateperone (developmental code names ITI-007, ITI-722) is an investigational atypical antipsychotic which is currently under development by Intra-Cellular Therapies, licensed from Bristol-Myers Squibb, for the treatment of schizophrenia.

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Meta-Chlorophenylpiperazine

meta-Chlorophenylpiperazine (mCPP) is a psychoactive drug of the phenylpiperazine class.

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MIN-117

MIN-117 (known formerly as WF-516) is an investigational antidepressant which is under development by Minerva Neurosciences for the clinical treatment of major depressive disorder (MDD).

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Mirtazapine

Mirtazapine, sold under the brand name Remeron among others, is an atypical antidepressant which is used primarily in the treatment of depression.

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Nefazodone

Nefazodone, sold formerly under the brand names Serzone, Dutonin, and Nefadar among others, is an atypical antidepressant which was first marketed by Bristol-Myers Squibb in 1994 but has since largely been discontinued.

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Nicergoline

Nicergoline (INN, marketed under the trade name Sermion) is an ergot derivative used to treat senile dementia and other disorders with vascular origins.

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Olanzapine

Olanzapine (originally branded Zyprexa) is an antipsychotic medication used to treat schizophrenia and bipolar disorder.

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Paliperidone

Paliperidone, sold under the trade name Invega among others, is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications.

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Perphenazine

Perphenazine is a typical antipsychotic drug.

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Pimozide

Pimozide (sold under the brand name Orap) is an antipsychotic drug of the diphenylbutylpiperidine class.

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Quetiapine

Quetiapine, marketed as Seroquel among other names, is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.

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Raymond P. Ahlquist

Raymond Perry Ahlquist (July 26, 1914 in Missoula, Montana – April 15, 1983 in Augusta, Georgia) was an American pharmacist and pharmacologist.

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Reboxetine

Reboxetine, sold under the brand name Edronax among others, is a drug of the norepinephrine reuptake inhibitor (NRI) class, marketed as an antidepressant by Pfizer for use in the treatment of major depression, although it has also been used off-label for panic disorder and attention deficit hyperactivity disorder (ADHD).

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Rhodopsin-like receptors

Rhodopsin-like receptors are a family of proteins that comprise the largest group of G protein-coupled receptors.

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Risperidone

Risperidone, sold under the trade name Risperdal among others, is an antipsychotic medication.

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Rotigotine

Rotigotine (Neupro) is a dopamine agonist of the non-ergoline class of medications indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS).

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Sertindole

Sertindole (brand names: Serdolect and Serlect) is an antipsychotic medication.

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Silodosin

No description.

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Spiperone

Spiperone (Spiroperidol; brand name: Spiropitan (JP)) is a typical antipsychotic and research chemical belonging to the butyrophenone chemical class.

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Tamsulosin

Tamsulosin, sold under the trade name Alna ® / Flomax ®, is a medication used to treat symptomatic benign prostatic hyperplasia (BPH) and chronic prostatitis, help with the passage of kidney stones, and for urinary retention along with other measures.

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Tedatioxetine

Tedatioxetine (Lu AA24530) is an antidepressant that was discovered by scientists at Lundbeck; in 2007 Lundbeck and Takeda entered into a partnership that included tedatioxetine but was focused on another, more advanced Lundbeck drug candidate, vortioxetine.

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Thioridazine

Thioridazine (Mellaril or Melleril) is a piperidine typical antipsychotic drug belonging to the phenothiazine drug group and was previously widely used in the treatment of schizophrenia and psychosis.

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Tianeptine

Tianeptine, sold under the brand names Stablon and Coaxil among others, is an atypical antidepressant which is used mainly in the treatment of major depressive disorder, although it may also be used to treat anxiety, asthma, and irritable bowel syndrome.

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Tiotixene

Tiotixene, or thiothixene, sold under the brand name Navane among others, is a typical antipsychotic of the thioxanthene class which is related to chlorprothixene and is used in the treatment of psychoses like schizophrenia and bipolar mania.

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Trazodone

Trazodone, sold under many brand names worldwide, Page accessed Feb 10, 2016 is an antidepressant medication.

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Yohimbine

Yohimbine is an indole alkaloid derived from the bark of the Pausinystalia yohimbe tree in Central Africa.

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Ziprasidone

Ziprasidone, sold under the brand name Geodon among others, is an atypical antipsychotic which is used for the treatment of schizophrenia as well as acute mania and mixed states associated with bipolar disorder.

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Zotepine

Zotepine (brand names: Losizopilon (JP), Lodopin (ID, JP), Setous (JP), Zoleptil (CZ, PT, TR, UK†); where † indicates a formulation that has been discontinued) is an atypical antipsychotic drug indicated for acute and chronic schizophrenia.

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1A

1A or 1-A may refer to.

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5'-Guanidinonaltrindole

5'-Guanidinonaltrindole (5'-GNTI) is an opioid antagonist used in scientific research which is highly selective for the κ opioid receptor.

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Redirects here:

A1c receptor, ADRA1A, ADRA1A (gene), Alpha-1A, Alpha-1C adrenergic receptor, Alpha-1a adrenergic receptor, Alpha-1a receptor, Α-1c receptor, Α1A-adrenergic, Α1A-adrenergic receptor.

References

[1] https://en.wikipedia.org/wiki/Alpha-1A_adrenergic_receptor

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