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Anaphylatoxin

Index Anaphylatoxin

Anaphylatoxins, or complement peptides, are fragments (C3a, C4a and C5a) that are produced as part of the activation of the complement system. [1]

26 relations: Anaphylatoxin receptors, Bronchospasm, C3-convertase, C3a (complement), Capillary, Chondroitin sulfate, Complement component 3, Complement component 4, Complement component 5, Complement component 5a, Complement system, Ernst Friedberger, Fibulin, Frederick George Novy, G protein–coupled receptor, GPR77, Hereditary angioedema, Inflammation, Intraoperative blood salvage, List of MeSH codes (D12.776.124), Ludwik Hirszfeld, Lysine carboxypeptidase, Peanut allergy, Properdin, Thioester-containing protein 1, Type III hypersensitivity.

Anaphylatoxin receptors

The anaphylatoxin receptors are a group of G-protein coupled receptors which bind anaphylatoxins.

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Bronchospasm

Bronchospasm or a bronchial spasm is a sudden constriction of the muscles in the walls of the bronchioles.

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C3-convertase

C3 convertase (C2, C4bC2b, (formerly C4bC2a)C3bBb, complement C.hivin.4.hivin2, complement C3 convertase) belongs to family of serine proteases and is necessary in innate immunity as a part of the complement system which eventuate in opsonisation of particles, release of inflammatory peptides, C5 convertase formation and cell lysis.

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C3a (complement)

C3a is one of the proteins formed by the cleavage of complement component 3; the other is C3b.

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Capillary

A capillary is a small blood vessel from 5 to 10 micrometres (µm) in diameter, and having a wall one endothelial cell thick.

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Chondroitin sulfate

Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) composed of a chain of alternating sugars (N-acetylgalactosamine and glucuronic acid).

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Complement component 3

Complement component 3, often simply called C3, is a protein of the immune system.

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Complement component 4

Complement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human leukocyte antigen (HLA) system.

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Complement component 5

Complement component 5 is a protein that in humans is encoded by the C5 gene.

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Complement component 5a

C5a is a protein fragment released from cleavage of complement component C5 by protease C5-convertase into C5a and C5b fragments.

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Complement system

The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane.

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Ernst Friedberger

Ernst Friedberger (May 17, 1875 - January 25, 1932) was a German immunologist and hygienist born in Giessen.

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Fibulin

Fibulin (FY-beau-lin) (now known as Fibulin-1 FBLN1) is the prototypic member of a multigene family, currently with seven members.

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Frederick George Novy

Frederick George Novy (December 9, 1864 – August 8, 1957) was an American bacteriologist, organic chemist, and instructor.

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G protein–coupled receptor

G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.

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GPR77

C5a anaphylatoxin chemotactic receptor C5a2 also known as C5L2, G protein-coupled receptor 77, is a protein that in humans is encoded by the C5AR2 gene.

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Hereditary angioedema

Hereditary angioedema (HAE) is a disorder that results in recurrent attacks of severe swelling.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Intraoperative blood salvage

Intraoperative blood salvage, also known as autologous blood transfusion or cell salvage, is a medical procedure involving recovering blood lost during surgery and re-infusing it into the patient.

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List of MeSH codes (D12.776.124)

This is a sub-part (blood proteins only) of List of MeSH codes (D12.776), itself a part of the list of the "D" codes for MeSH.

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Ludwik Hirszfeld

Ludwik Hirszfeld (5 August 1884 in Warsaw – 7 March 1954 in Wrocław) was a Polish microbiologist and serologist.

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Lysine carboxypeptidase

Lysine carboxypeptidase (carboxypeptidase N, arginine carboxypeptidase, kininase I, anaphylatoxin inactivator, plasma carboxypeptidase B, creatine kinase conversion factor, bradykinase, kininase Ia, hippuryllysine hydrolase, bradykinin-decomposing enzyme, protaminase, CPase N, creatinine kinase convertase, peptidyl-L-lysine(-L-arginine) hydrolase, CPN) is an enzyme.

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Peanut allergy

Peanut allergy is a type of food allergy to peanuts.

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Properdin

Properdin is the only known positive regulator of complement activation that stabilizes the alternative pathway convertases.

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Thioester-containing protein 1

Thioester containing protein 1, often simply referred to as TEP1 is a key component of the arthropod innate immune system.

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Type III hypersensitivity

Type III hypersensitivity occurs when there is accumulation of immune complexes (antigen-antibody complexes) that have not been adequately cleared by innate immune cells, giving rise to an inflammatory response and attraction of leukocytes.

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Redirects here:

Anaphylatoxins, Anaphylotoxin.

References

[1] https://en.wikipedia.org/wiki/Anaphylatoxin

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