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Antiandrogen

Index Antiandrogen

Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body. [1]

196 relations: AA, Abiraterone acetate, Acne, Algestone acetophenide, Allyltestosterone, Amadinone, Anabolic steroid, Anaphrodisiac, Andarine, Androgen, Androgen deprivation therapy, Androgen suppression, Androgen-dependent condition, Angelica gigas, Antiandrogens in the environment, Anticorticotropin, Antiestrogen, Antigonadotropin, Antihormone therapy, Antimineralocorticoid, Antiprogestogen, Apalutamide, ATC code G03, Atraric acid, Bakuchiol, Benorterone, Bicalutamide, Bifluranol, Bis(2-ethylhexyl) phthalate, Bisphenol A diglycidyl ether, BMS-641988, Brassica, Breast atrophy, Canrenone, Castration, Chemical castration, Chlormadinone acetate, Cimetidine, Clometerone, Comparison of bicalutamide with other antiandrogens, Cortisone reductase deficiency, CYP17A1 inhibitor, CYP2C19, CYP2C8, CYP3A4, Cyproterone acetate, Degarelix, Dehydroepiandrosterone, Delanterone, Delmadinone acetate, ..., Demegestone, Depressogenic, Desire discrepancy, Desogestrel, Dicarboximide fungicides, Dicirenone, Dieldrin, Dienogest, Dienolone, Dimethylcurcumin, Discovery and development of antiandrogens, Dorian Gray syndrome, Drospirenone, Drupanol, Dutasteride, Dydrogesterone, Edogestrone, EM-5854, Endosulfan, Enzalutamide, EPI-001, Eplerenone, Essential oil, Estetrol (medication), Estradiol (medication), Estrogen (medication), Ethinylestradiol, Ethinylestradiol sulfonate, Ethyltestosterone, Fenarimol, Fibroadenoma, Finasteride, Gender, Gender dysphoria, Gender taxonomy, Gestonorone caproate, Gonadotropin-releasing hormone antagonist, Goserelin, Gynecomastia, Hair removal, Hidradenitis suppurativa, Hirsutism, Hormonal breast enhancement, Hormonal therapy (oncology), Hot flash, HSD17B2, Hydroxyprogesterone caproate, Hyperandrogenism, Hypergonadotropic hypogonadism, Hypersexuality, Index of oncology articles, Intermammary cleft, Janae Kroc, Ketoconazole, Larry Goldenberg, Leuprorelin, Levonorgestrel, List of androgens/anabolic steroids, List of antiandrogens, List of investigational hormonal agents, List of MeSH codes (D06), List of MeSH codes (D16), List of transgender publications, Male breast cancer, Mammoplasia, Management of prostate cancer, Medication, Medrogestone, Medroxyprogesterone acetate, Megestrol acetate, Mespirenone, Mesterolone, Methiocarb, Methyltestosterone, Metogest, Metribolone, Mexrenone, Mifepristone, N-Terminal domain antiandrogen, Nandrolone decanoate, Nandrolone phenylpropionate, Nomegestrol acetate, Nonsteroidal, Nonsteroidal antiandrogen, Nordinone, Norgestimate, Off-target activity, Onapristone, Osaterone, Osaterone acetate, Oxendolone, Paraphilia, Pedophilia, Peripherally selective drug, Persistent organic pollutant, Phenothrin, Phthalate, Plastic pollution, Polycystic ovary syndrome, Pregnadiene, Prevention Project Dunkelfeld, Primary aldosteronism, Progesterone (medication), Progestin, Progonadotropin, Promegestone, Psychosexual disorder, Puberty blocker, RD-162, RU-59063, Sari (disambiguation), SC-5233, SC-8109, Seborrhoeic dermatitis, Segesterone acetate, Seviteronel, Sex change, Sex effects of water pollution, Sex-hormonal agent, Sexual fetishism, Spirolactone, Spironolactone, Spirorenone, Spiroxasone, Stan Lazaridis, Steroidal antiandrogen, Structure–activity relationships of anabolic steroids, Testosterone, Testosterone (medication), Toxicodynamics, Transgender hormone therapy, Transgender hormone therapy (male-to-female), Trimegestone, Trimethyltrienolone, Valproate, Vinclozolin, 1-Keto-1,2,3,4-tetrahydrophenanthrene, 11α-Hydroxyprogesterone, 17α-Alkylated anabolic steroid, 17α-Allyl-19-nortestosterone, 4-Androstenediol, 5α-Dihydroethisterone, 5α-Reductase inhibitor, 7α-Thiomethylspironolactone, 7α-Thioprogesterone, 7α-Thiospironolactone. Expand index (146 more) »

AA

AA or Aa may refer to.

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Abiraterone acetate

Abiraterone acetate, sold under the brand name Zytiga among others, is an antiandrogen medication which is used in the treatment of prostate cancer.

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Acne

Acne, also known as acne vulgaris, is a long-term skin disease that occurs when hair follicles are clogged with dead skin cells and oil from the skin.

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Algestone acetophenide

Algestone acetophenide, also known as dihydroxyprogesterone acetophenide (DHPA) and sold under the brand name Deladroxate among others, is a progestin medication which is used in combination with an estrogen as a form of long-lasting injectable birth control.

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Allyltestosterone

Allyltestosterone, or 17α-allyltestosterone, also known as 17α-allylandrost-4-en-17β-ol-3-one, is a steroid derived from testosterone that was first synthesized in 1936 and was never marketed.

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Amadinone

Amadinone (INN), also known as 19-norchlormadinone, is a steroidal progestin of the 19-norprogesterone and 17α-hydroxyprogesterone groups that was synthesized and characterized in 1968 but was never marketed.

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Anabolic steroid

Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.

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Anaphrodisiac

An anaphrodisiac (also antaphrodisiac or antiaphrodisiac) is a substance that quells or blunts the libido.

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Andarine

Andarine (developmental code names GTx-007, S-4) is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy, using the nonsteroidal antiandrogen bicalutamide as a lead compound.

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Androgen

An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.

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Androgen deprivation therapy

Androgen deprivation therapy (ADT), also called androgen suppression therapy, is an antihormone therapy whose main use is in treating prostate cancer.

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Androgen suppression

Androgen suppression, also called androgen ablation or androgen deprivation, is a medical treatment to suppress or block the production or action of male sex hormones, typically in order to attempt to treat certain types of cancer that rely upon male hormones for its growth.

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Androgen-dependent condition

An androgen-dependent condition, disease, disorder, or syndrome, is a medical condition that is, in part or full, dependent on, or is sensitive to, the presence of androgenic activity in the body.

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Angelica gigas

Angelica gigas, also called Korean angelica, giant Angelica, purple parsnip, and dangquai, is a monocarpic biennial or short lived perennial plant from China, Japan and Korea.

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Antiandrogens in the environment

Antiandrogens in the environment have become a topic of concern.

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Anticorticotropin

An anticorticotropin, or anticorticotrophin, is a drug which opposes the actions of corticotropin-releasing hormone (CRH) and/or adrenocorticotropic hormone (ACTH) in relation to their stimulatory effects on the adrenal glands, or which otherwise suppresses steroid hormone production in the adrenal glands.

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Antiestrogen

Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body.

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Antigonadotropin

An antigonadotropin is a drug which suppresses the activity and/or downstream effects of one or both of the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH).

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Antihormone therapy

Antihormone therapy is a type of hormone therapy that suppresses selected hormones or their effects, in contrast with hormone replacement therapy, which encourages hormone activity.

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Antimineralocorticoid

An antimineralocorticoid, MCRA, or an aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors.

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Antiprogestogen

Antiprogestogens, or antiprogestins, also known as progesterone antagonists or progesterone blockers, are a class of drugs which prevent progestogens like progesterone from mediating their biological effects in the body.

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Apalutamide

Apalutamide, sold under the brand name Erleada, is a nonsteroidal antiandrogen (NSAA) medication which is used in the treatment of prostate cancer.

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ATC code G03

G03.

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Atraric acid

Atraric Acid is a naturally occurring phenolic compound and ester with the IUPAC name methyl 2,4-dihydroxy-3,6-dimethylbenzoate and molecular formula C10H12O4.

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Bakuchiol

Bakuchiol is a meroterpene (a chemical compound having a partial terpenoid structure) in the class terpenophenol.

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Benorterone

Benorterone, also known by its developmental code name SKF-7690 and as 17α-methyl-B-nortestosterone, is an steroidal antiandrogen which was studied for potential medical use but was never marketed.

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Bicalutamide

Bicalutamide, sold under the brand name Casodex among others, is an antiandrogen medication that is primarily used to treat prostate cancer.

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Bifluranol

Bifluranol (brand name Prostarex; former developmental code name BX-341) is a synthetic nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol that has been used as an antiandrogen in the United Kingdom in the treatment of benign prostatic hyperplasia.

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Bis(2-ethylhexyl) phthalate

Bis(2-ethylhexyl) phthalate (di-2-ethylhexyl phthalate, diethylhexyl phthalate, DEHP; dioctyl phthalate, DOP) is an organic compound with the formula C6H4(CO2C8H17)2.

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Bisphenol A diglycidyl ether

Bisphenol A diglycidyl ether (commonly abbreviated BADGE or DGEBA) is an organic compound used as constituent of epoxy resins.

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BMS-641988

BMS-641988 is a nonsteroidal antiandrogen which was developed by Bristol-Myers Squibb for the treatment of prostate cancer but was never marketed.

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Brassica

Brassica is a genus of plants in the mustard family (Brassicaceae).

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Breast atrophy

Breast atrophy is the normal or spontaneous atrophy or shrinkage of the breasts.

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Canrenone

Canrenone, sold under the brand names Contaren, Luvion, Phanurane, and Spiroletan, is a steroidal antimineralocorticoid of the spirolactone group related to spironolactone which is used as a diuretic in Europe, including in Italy and Belgium.

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Castration

Castration (also known as gonadectomy) is any action, surgical, chemical, or otherwise, by which an individual loses use of the testicles.

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Chemical castration

Chemical castration is castration via anaphrodisiac drugs, whether to reduce libido and sexual activity, to treat cancer, or otherwise.

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Chlormadinone acetate

Chlormadinone acetate (CMA), sold under the brand names Belara, Lutéran, and Prostal among others, is a progestin and antiandrogen medication which is used in birth control pills to prevent pregnancy, as a component of menopausal hormone therapy, and in the treatment of gynecological disorders as well as androgen-dependent conditions like enlarged prostate and prostate cancer in men and acne and hirsutism in women.

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Cimetidine

Cimetidine, sold under the brand name Tagamet among others, is a histamine H2 receptor antagonist that inhibits stomach acid production.

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Clometerone

Clometerone (developmental code name L-38000), or clometherone, also known as 6α-chloro-16α-methylprogesterone, is a synthetic pregnane steroid and derivative of progesterone which was reported in 1962 and is described as an antiestrogen and antiandrogen but was never marketed.

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Comparison of bicalutamide with other antiandrogens

Comparison of the nonsteroidal antiandrogen (NSAA) bicalutamide with other antiandrogens reveals differences between the medications in terms of efficacy, tolerability, safety, and other parameters.

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Cortisone reductase deficiency

Cortisone reductase deficiency is caused by dysregulation of the 11β-hydroxysteroid dehydrogenase type 1 enzyme (11β-HSD1), otherwise known as cortisone reductase, a bi-directional enzyme, which catalyzes the interconversion of cortisone to cortisol in the presence of NADH as a co-factor.

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CYP17A1 inhibitor

A CYP17A1 inhibitor is a type of drug which inhibits the enzyme CYP17A1.

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CYP2C19

Cytochrome P450 2C19 (abbreviated CYP2C19) is an enzyme.

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CYP2C8

Cytochrome P4502C8 (abbreviated CYP2C8), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body.

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CYP3A4

Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.

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Cyproterone acetate

Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol (EE) under the brand names Diane or Diane-35 among others, is an antiandrogen and progestogen which is used in the treatment of androgen-dependent conditions like acne, excessive hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender women, and in birth control pills.

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Degarelix

Degarelix or degarelix acetate, sold under the brand name Firmagon among others, is a hormonal therapy used in the treatment of prostate cancer.

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Dehydroepiandrosterone

Dehydroepiandrosterone (DHEA), also known as androstenolone, is an endogenous steroid hormone.

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Delanterone

Delanterone (developmental code name GBR-21162), also known as 1α-methylandrosta-4,16-dien-3-one, is a steroidal antiandrogen described as an anti-acne agent which was never marketed.

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Delmadinone acetate

Delmadinone acetate (DMA), sold under the brand name Tardak among others, is a progestin and antiandrogen which is used in veterinary medicine to treat androgen-dependent conditions such as benign prostatic hyperplasia.

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Demegestone

Demegestone, sold under the brand name Lutionex, is a progestin medication which was previously used to treat luteal insufficiency but is now no longer marketed.

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Depressogenic

A depressogenic substance (or depressogen) is one that causes or can cause depression, usually as a side effect.

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Desire discrepancy

Sexual desire discrepancy (SDD) is the difference between one's desired frequency of sexual intercourse and the actual frequency of sexual intercourse within a relationship.

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Desogestrel

Desogestrel, sold under the brand names Cerazette and Mircette among many others, is a progestin medication which is used in birth control pills for women.

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Dicarboximide fungicides

Dicarboximide (or dicarboxamide) fungicides are a family of agricultural fungicides that include vinclozolin, iprodione, and procymidone.

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Dicirenone

Dicirenone (INN, USAN; developmental code name SC-26304; also known as 7α-carboxyisopropylspirolactone) is a synthetic, steroidal antimineralocorticoid of the spirolactone group which was developed as a diuretic and antihypertensive agent but was never marketed.

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Dieldrin

Dieldrin is an organochloride originally produced in 1948 by J. Hyman & Co, Denver, as an insecticide.

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Dienogest

Dienogest, sold under the brand names Natazia and Qlaira among others, is a progestin medication which is used in birth control pills and in the treatment of endometriosis.

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Dienolone

Dienolone (developmental code name RU-3118; online product names Trenazone, Dienazone), or nordienolone, also known as 19-nor-δ9(10)-testosterone, δ9(10)-nandrolone, or estra-4,9(10)-dien-17β-ol-3-one, is a synthetic anabolic-androgenic steroid (AAS) of the 19-nortestosterone group that was never marketed.

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Dimethylcurcumin

Dimethylcurcumin (developmental code name ASC-J9) is a nonsteroidal antiandrogen and a synthetic curcuminoid which is under development by AndroScience Corporation as a topical medication for the treatment of acne vulgaris.

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Discovery and development of antiandrogens

This article is about the discovery and development of antiandrogens, or androgen receptor (AR) antagonists.

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Dorian Gray syndrome

The Dorian Gray syndrome (DGS) denotes a cultural and societal phenomenon characterized by a man's extreme pride in his personal appearance and the fitness of his physique, which is accompanied by difficulties in coping with the requirements of psychological maturation and with the aging of his body.

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Drospirenone

Drospirenone, sold under the brand names Yasmin and Angeliq among others, is a progestin medication which is used in birth control pills and in menopausal hormone therapy. The medication is available only in combination with an estrogen. It is taken by mouth. Drospirenone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has additional antimineralocorticoid and antiandrogenic activity and no other important hormonal activity. Drospirenone was introduced for medical use in 2000. It is available widely throughout the world. The medication is sometimes referred to as a "fourth-generation" progestin. It is available as a generic medication.https://www.drugs.com/availability/generic-yasmin.html.

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Drupanol

Drupanol is a naturally occurring phenol that has been isolated from the seeds of Psoralea drupaceae.

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Dutasteride

Dutasteride, sold under the brand name Avodart among others, is a medication used primarily to treat enlarged prostate in men.

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Dydrogesterone

Dydrogesterone, sold under the brand name Duphaston among others, is a progestin medication which is used for a variety of indications, including threatened or recurrent miscarriage during pregnancy, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhea, irregular cycles, premenstrual syndrome, and as a component of menopausal hormone therapy.

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Edogestrone

Edogestrone (developmental code name PH-218), or edogesterone, also known as 17α-acetoxy-3,3-ethylenedioxy-6-methylpregn-5-en-20-one, is a steroidal progestin and antiandrogen of the 17α-hydroxyprogesterone group which was synthesized in 1964 but was never marketed.

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EM-5854

EM-5854 is a steroidal antiandrogen which is or was under development by Endoceutics, Inc.

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Endosulfan

Endosulfan is an off-patent organochlorine insecticide and acaricide that is being phased out globally.

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Enzalutamide

Enzalutamide, sold under the brand name Xtandi, is a nonsteroidal antiandrogen (NSAA) medication which is used in the treatment of prostate cancer.

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EPI-001

EPI-001 is a novel experimental nonsteroidal antiandrogen (NSAA) that is under investigation for the treatment of prostate cancer.

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Eplerenone

Eplerenone is a steroidal antimineralocorticoid of the spirolactone group that is used as an adjunct in the management of chronic heart failure.

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Essential oil

An essential oil is a concentrated hydrophobic liquid containing volatile (defined as "the tendency of a substance to vaporize") aroma compounds from plants.

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Estetrol (medication)

Estetrol, tentative brand names Donesta (alone) and Estelle (with drospirenone), is an estrogen medication and naturally occurring steroid hormone which is under development for use as a birth control pill in combination with a progestin, in menopausal hormone therapy to treat symptoms such as vaginal atrophy, hot flashes, and bone loss, and for the treatment of breast cancer, prostate cancer, osteoarthritis, and migraine.

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Estradiol (medication)

Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.

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Estrogen (medication)

An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Ethinylestradiol

Ethinylestradiol (EE) is an estrogen medication which is used widely in birth control pills in combination with progestins.

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Ethinylestradiol sulfonate

Ethinylestradiol sulfonate (EES) (brand name Turisteron), also known as ethinylestradiol isopropylsulfonate or ethinylestradiol propanesulfate, as well as 17α-ethynyl-3-isopropylsulfonyloxyestradiol, is a synthetic, steroidal estrogen that is marketed in Germany.

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Ethyltestosterone

Ethyltestosterone, or 17α-ethyltestosterone, also known as 17α-ethylandrost-4-en-17β-ol-3-one or 17α-pregn-4-en-17-ol-3-one, is a synthetic, orally active anabolic–androgenic steroid (AAS) of the 17α-alkylated group related to methyltestosterone which was never marketed.

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Fenarimol

Fenarimol, sold under the tradenames Bloc, Rimidin and Rubigan, is a fungicide which acts against rusts, blackspot and mildew fungi.

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Fibroadenoma

Fibroadenomas, are benign breast tumours characterized by an admixture of stromal and epithelial tissue.

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Finasteride

Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used mainly to treat an enlarged prostate or scalp hair loss in men.

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Gender

Gender is the range of characteristics pertaining to, and differentiating between, masculinity and femininity.

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Gender dysphoria

Gender dysphoria (GD), or gender identity disorder (GID), is the distress a person experiences as a result of the sex and gender they were assigned at birth.

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Gender taxonomy

The gender taxonomy is a classification of the range of different levels at which humans vary in sexual characteristics.

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Gestonorone caproate

Gestonorone caproate, also known as gestronol hexanoate or norhydroxyprogesterone caproate and sold under the brand names Depostat and Primostat, is a progestin medication which is used in the treatment of enlarged prostate and endometrial cancer.

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Gonadotropin-releasing hormone antagonist

Gonadotropin-releasing hormone antagonists (GnRH antagonists) are a class of medications that antagonize the gonadotropin-releasing hormone receptor (GnRH receptor) and thus the action of gonadotropin-releasing hormone (GnRH).

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Goserelin

Goserelin, or goserelin acetate, sold under the brand name Zoladex (by AstraZeneca) among others, is a medication which is used to suppress production of the sex hormones (testosterone and estrogen), particularly in the treatment of breast and prostate cancer.

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Gynecomastia

Gynecomastia is an endocrine system disorder in which a noncancerous increase in the size of male breast tissue occurs.

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Hair removal

Hair removal, also known as epilation or depilation, is the deliberate removal of body hair.

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Hidradenitis suppurativa

Hidradenitis suppurativa (HS), also known as acne inversa, is a long term skin disease characterized by the occurrence of inflamed and swollen lumps.

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Hirsutism

Hirsutism is excessive body hair in men and women on parts of the body where hair is normally absent or minimal, such as on the chin or chest in particular, or the face or body in general.

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Hormonal breast enhancement

Hormonal breast enhancement or augmentation is a highly experimental potential medical treatment for the breasts in which hormones or hormonal agents such as estrogen, progesterone, growth hormone (GH), and insulin-like growth factor 1 (IGF-1) are utilized or manipulated to produce breast enlargement in women.

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Hormonal therapy (oncology)

Hormonal therapy in oncology is hormone therapy for cancer and is one of the major modalities of medical oncology (pharmacotherapy for cancer), others being cytotoxic chemotherapy and targeted therapy (biotherapeutics).

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Hot flash

Hot flashes (American English) or hot flushes (British English) are a form of flushing due to reduced levels of estradiol.

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HSD17B2

17β-Hydroxysteroid dehydrogenase 2 (17β-HSD2) is an enzyme of the 17β-hydroxysteroid dehydrogenase (17β-HSD) family that in humans is encoded by the HSD17B2 gene.

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Hydroxyprogesterone caproate

Hydroxyprogesterone caproate (OHPC), sold under the brand names Proluton and Makena among others, is a progestin medication which is used to prevent preterm birth in pregnant women with a history of the condition and to treat gynecological disorders.

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Hyperandrogenism

Hyperandrogenism, also known as androgen excess, is a medical condition characterized by excessive levels of androgens (male sex hormones such as testosterone) in the female body and the associated effects of the elevated androgen levels.

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Hypergonadotropic hypogonadism

Hypergonadotropic hypogonadism (HH), also known as primary or peripheral/gonadal hypogonadism, is a condition which is characterized by hypogonadism due to an impaired response of the gonads to the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), and in turn a lack of sex steroid production and elevated gonadotropin levels (as an attempt of compensation by the body).

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Hypersexuality

Hypersexuality is a clinical diagnosis used by mental healthcare professionals to describe extremely frequent or suddenly increased libido.

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Index of oncology articles

This is a list of terms related to oncology.

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Intermammary cleft

In female human anatomy, the intermammary cleft or intermammary sulcus or sulcus intermammarius of a woman is delineated by where the fatty portions of each breast sits in relationship to the sternum (or breastbone).

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Janae Kroc

Janae Marie Kroczaleski (born: Matthew Raymond Kroczaleski) is an American who previously competed as a professional powerlifter and competitive bodybuilder.

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Ketoconazole

Ketoconazole is a synthetic imidazole antifungal drug used primarily to treat fungal infections.

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Larry Goldenberg

S.

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Leuprorelin

Leuprorelin, also known as leuprolide, is a manufactured version of a hormone used to treat prostate cancer, breast cancer, endometriosis, uterine fibroids, and early puberty.

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Levonorgestrel

Levonorgestrel is a hormonal medication which is used in a number of birth control methods.

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List of androgens/anabolic steroids

This is a list of androgens/anabolic steroids (AAS) or testosterone derivatives.

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List of antiandrogens

This is a list of antiandrogens, or drugs that prevent the effects of androgens like testosterone and dihydrotestosterone (DHT).

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List of investigational hormonal agents

This is a list of investigational hormonal agents, or hormonal agents that are currently under development for clinical use but are not yet approved.

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List of MeSH codes (D06)

This is the fourth part of the list of the "D" codes for MeSH.

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List of MeSH codes (D16)

This is the fourth part of the list of the "D" codes for MeSH.

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List of transgender publications

This list of transgender publications includes books, magazines, and academic journals about transgender people, culture, and thought.

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Male breast cancer

Male breast cancer (male breast neoplasm) is a rare cancer in males that originates from the breast.

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Mammoplasia

Mammoplasia is the normal or spontaneous enlargement of human breasts.

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Management of prostate cancer

Treatment for prostate cancer may involve active surveillance, surgery, radiation therapy including brachytherapy (prostate brachytherapy) and external beam radiation therapy, high-intensity focused ultrasound (HIFU), cryosurgery, hormonal therapy, chemotherapy, or some combination.

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Medication

A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Medrogestone

Medrogestone, sold under the brand name Colprone among others, is a progestin medication which has been used in menopausal hormone therapy and in the treatment of gynecological disorders.

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Medroxyprogesterone acetate

Medroxyprogesterone acetate (MPA), sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type.

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Megestrol acetate

Megestrol acetate (MGA), sold under the brand name Megace among others, is a progestin medication which is used mainly as an appetite stimulant to treat wasting syndromes such as cachexia.

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Mespirenone

Mespirenone (INN) (developmental code name ZK-94679), also known as Δ1-15β,16β-methylenespironolactone, is a steroidal antimineralocorticoid of the spirolactone group related to spironolactone that was never marketed.

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Mesterolone

Mesterolone, sold under the brand name Proviron among others, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels.

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Methiocarb

Methiocarb is a carbamate pesticide which is used as a bird repellent, insecticide, acaricide and molluscicide since the 1960s.

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Methyltestosterone

Methyltestosterone, sold under the brand names Android, Metandren, and Testred among others, is an androgen and anabolic steroid (AAS) medication which is used in the treatment of low testosterone levels in men, delayed puberty in boys, at low doses as a component of menopausal hormone therapy for menopausal symptoms like hot flashes, osteoporosis, and low sexual desire in women, and to treat breast cancer in women.

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Metogest

Metogest (INN, USAN) (developmental code name SC-14207), also known as 16,16-dimethyl-19-nortestosterone, is a steroidal antiandrogen that was patented in 1975 and investigated as a treatment for acne but was never marketed.

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Metribolone

Metribolone (developmental code name R1881), also known as methyltrienolone, is a synthetic and orally active anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was never marketed for medical use but has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR.

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Mexrenone

Mexrenone (code names ZK-32055, SC-25152) is a steroidal antimineralocorticoid of the spirolactone group related to spironolactone that was never marketed.

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Mifepristone

Mifepristone, also known as RU-486, is a medication typically used in combination with misoprostol, to bring about an abortion.

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N-Terminal domain antiandrogen

N-Terminal domain antiandrogens are a novel type of antiandrogen that bind to the ''N''-terminal domain of the androgen receptor (AR) instead of the ligand-binding domain (where all currently-available antiandrogens bind) and disrupt interactions between the AR and its coregulatory binding partners, thereby blocking AR-mediated gene transcription.

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Nandrolone decanoate

Nandrolone decanoate, sold under the brand name Deca-Durabolin among others, is an androgen and anabolic steroid (AAS) medication which is used primarily in the treatment of anemias and wasting syndromes, as well as osteoporosis in menopausal women.

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Nandrolone phenylpropionate

Nandrolone phenylpropionate (NPP), or nandrolone phenpropionate, sold under the brand name Durabolin among others, is an androgen and anabolic steroid (AAS) medication which has been used primarily in the treatment of breast cancer and osteoporosis in women.

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Nomegestrol acetate

Nomegestrol acetate (NOMAC), sold under the brand names Lutenyl and Zoely among others, is a progestin medication which is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders.

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Nonsteroidal

Nonsteroidal is a term which is used to describe a compound that is not a steroid.

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Nonsteroidal antiandrogen

A nonsteroidal antiandrogen (NSAA) is an antiandrogen with a nonsteroidal chemical structure.

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Nordinone

Nordinone (INN), also known as 11α-hydroxy-17,17-dimethyl-18-norandrosta-4,13-dien-3-one, is a naturally occurring steroid with antiandrogen properties isolated as a metabolite from the fungus Monocillium nordinii.

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Norgestimate

Norgestimate, sold under the brand names Ortho Tri-Cyclen and Previfem among others, is a progestin medication which is used in birth control pills for women and in menopausal hormone therapy.

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Off-target activity

Off-target activity is biological activity of a drug that is different from and not at that of its intended biological target.

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Onapristone

Onapristone (INN) (developmental code names ZK-89299, ZK-299) is a synthetic, steroidal antiprogestogen with additional antiglucocorticoid activity which was developed by Schering and described in 1984 but was never marketed.

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Osaterone

Osaterone (developmental code name TZP-5258), also known as 17α-hydroxy-6-chloro-2-oxa-6-dehydroprogesterone, as well as 2-oxachloromadinone, is a steroidal antiandrogen and progestin that was never marketed.

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Osaterone acetate

Osaterone acetate, sold under the brand name Ypozane, is a medication which is used in veterinary medicine in Europe in the treatment of enlarged prostate in dogs.

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Oxendolone

Oxendolone, sold under the brand names Prostetin and Roxenone, is an antiandrogen and progestin medication which is used in Japan in the treatment of enlarged prostate.

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Paraphilia

Paraphilia (previously known as sexual perversion and sexual deviation) is the experience of intense sexual arousal to atypical objects, situations, fantasies, behaviors, or individuals.

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Pedophilia

Pedophilia, or paedophilia, is a psychiatric disorder in which an adult or older adolescent experiences a primary or exclusive sexual attraction to prepubescent children.

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Peripherally selective drug

Peripherally selective drugs have their primary mechanism of action outside of the central nervous system (CNS), usually because they are excluded from the CNS by the blood-brain barrier.

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Persistent organic pollutant

Persistent organic pollutants (POPs) are organic compounds that are resistant to environmental degradation through chemical, biological, and photolytic processes.

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Phenothrin

Phenothrin, also called sumithrin and d-phenothrin, is a synthetic pyrethroid that kills adult fleas and ticks.

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Phthalate

Phthalates, or phthalate esters, are esters of phthalic acid.

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Plastic pollution

Plastic pollution is the accumulation of plastic products in the environment that adversely affects wildlife, wildlife habitat and humans.

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Polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is a set of symptoms due to elevated androgens (male hormones) in females.

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Pregnadiene

A pregnadiene is a diene derivative of a pregnane.

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Prevention Project Dunkelfeld

The Prevention Project Dunkelfeld (PPD) is an effort founded in Germany to provide clinical and support services to individuals who are sexually attracted to children (pedophiles and hebephiles) and want help controlling their sexual urges, but are otherwise unknown to the legal authorities.

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Primary aldosteronism

Primary aldosteronism, also known as primary hyperaldosteronism or Conn's syndrome, refers to the excess production of the hormone aldosterone from the adrenal glands, resulting in low renin levels.

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Progesterone (medication)

Progesterone is a medication and naturally occurring steroid hormone.

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Progestin

A progestin is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Progonadotropin

A progonadotropin, or hypergonadotropin, also known as a gonad stimulant, is a type of drug which increases the secretion of one or both of the major gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH).

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Promegestone

Promegestone, sold under the brand name Surgestone, is a progestin medication which is used in menopausal hormone therapy and in the treatment of gynecological disorders.

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Psychosexual disorder

Psychosexual disorder is a term which may simply refer to a sexual problem that is psychological, rather than physiological in origin.

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Puberty blocker

Puberty blockers, also called puberty inhibitors, puberty suppressors, or hormone suppressors, are a group of medications used to inhibit puberty.

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RD-162

RD-162 is a second-generation nonsteroidal antiandrogen (NSAA) which was developed for the treatment of prostate cancer but was never marketed.

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RU-59063

RU-59063 is a nonsteroidal androgen or selective androgen receptor modulator (SARM) which was first described in 1994 and was never marketed.

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Sari (disambiguation)

A sari is a female garment in the Indian subcontinent.

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SC-5233

SC-5233, also known as 6,7-dihydrocanrenone or 20-spirox-4-ene-3,20-dione, is a synthetic, steroidal antimineralocorticoid of the spirolactone group which was developed by G. D. Searle & Company in the 1950s but was never marketed.

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SC-8109

SC-8109 is a steroidal antimineralocorticoid of the spirolactone group which was never marketed.

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Seborrhoeic dermatitis

Seborrhoeic dermatitis, also known as seborrhoea, is a long-term skin disorder.

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Segesterone acetate

Segesterone acetate (SGA), sold under the brand names Nestorone and Elcometrine, is a progestin medication which is used in birth control and in the treatment of endometriosis in Brazil and other South American countries.

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Seviteronel

Seviteronel (developmental codes VT-464 and, formerly, INO-464) is an experimental cancer medication which is under development by Viamet Pharmaceuticals and Innocrin Pharmaceuticals for the treatment of prostate cancer and breast cancer.

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Sex change

Sex change is a process by which a person or animal changes sex – that is, by which female sexual characteristics are substituted for male ones, or vice versa.

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Sex effects of water pollution

Sex is influenced by water pollutants that are encountered in everyday life.

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Sex-hormonal agent

A sex-hormonal agent, also known as a sex-hormone receptor modulator, is a type of hormonal agent which specifically modulates the effects of sex hormones and of their biological targets, the sex hormone receptors.

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Sexual fetishism

Sexual fetishism or erotic fetishism is a sexual fixation on a nonliving object or nongenital body part.

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Spirolactone

Spirolactones are a class of functional group in organic chemistry featuring a cyclic ester attatched spiro to another ring system.

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Spironolactone

Spironolactone, sold under the brand name Aldactone among others, is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.

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Spirorenone

Spirorenone (INN) (developmental code name ZK-35973) is a steroidal antimineralocorticoid of the spirolactone group that was never marketed.

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Spiroxasone

Spiroxasone (INN, USAN) is a synthetic, steroidal antimineralocorticoid of the spirolactone group which was developed as a diuretic and antihypertensive agent but was never marketed.

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Stan Lazaridis

Stanley Lazaridis (born 16 August 1972) is an Australian former footballer.

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Steroidal antiandrogen

A steroidal antiandrogen (SAA) is an antiandrogen with a steroidal chemical structure.

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Structure–activity relationships of anabolic steroids

The structure–activity relationships (SAR) of anabolic steroids (AAS) have been extensively studied.

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Testosterone

Testosterone is the primary male sex hormone and an anabolic steroid.

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Testosterone (medication)

Testosterone is a medication and naturally occurring steroid hormone.

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Toxicodynamics

Toxicodynamics, termed pharmacodynamics in pharmacology, describes the dynamic interactions of a toxicant with a biological target and its biological effects.

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Transgender hormone therapy

Transgender hormone therapy, also sometimes called cross-sex hormone therapy, is a form of hormone replacement therapy (HRT) in which sex hormones and other hormonal medications are administered to transgender or gender variant individuals for the purpose of more closely aligning their secondary sexual characteristics with their gender identity.

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Transgender hormone therapy (male-to-female)

Transgender hormone therapy of the male-to-female (MTF) type, also known as feminizing hormone therapy, is a form of hormone replacement therapy (HRT) and sex reassignment therapy which is used to change the secondary sexual characteristics of transgender people from masculine (or androgynous) to feminine.

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Trimegestone

Trimegestone, sold under the brand names Ondeva and Totelle among others, is a progestin medication which is used in menopausal hormone therapy and in the prevention of postmenopausal osteoporosis.

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Trimethyltrienolone

Trimethyltrienolone (TMT), also known by its developmental code name R-2956 or RU-2956, is an antiandrogen medication which was never introduced for medical use but has been used in scientific research.

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Valproate

Valproate (VPA), and its valproic acid, sodium valproate, and valproate semisodium forms, are medications primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches.

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Vinclozolin

Vinclozolin (trade names Ronilan, Curalan, Vorlan, Touche) is a common dicarboximide fungicide used to control diseases, such as blights, rots and molds in vineyards, and on fruits and vegetables such as raspberries, lettuce, kiwi, snap beans, and onions.

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1-Keto-1,2,3,4-tetrahydrophenanthrene

1-Keto-1,2,3,4-tetrahydrophenanthrene (THP-1), or 1,2,3,4-tetrahydrophenanthren-1-one, is a synthetic steroid-like compound which was reported to be the first synthetic estrogen, or the first synthetic compound identified with estrogenic activity.

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11α-Hydroxyprogesterone

11α-Hydroxyprogesterone (11α-OHP), or 11α-hydroxypregn-4-ene-3,20-dione is an endogenous steroid and metabolite of progesterone.

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17α-Alkylated anabolic steroid

A 17α-alkylated anabolic steroid is a synthetic anabolic–androgenic steroid (AAS) that features an alkyl group, specifically a methyl or ethyl group, at the C17α position.

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17α-Allyl-19-nortestosterone

17α-Allyl-19-nortestosterone, also known as 3-ketoallylestrenol or as 17α-allylestr-4-en-17β-ol-3-one, is a progestin which was never marketed.

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4-Androstenediol

4-Androstenediol, also known as androst-4-ene-3β,17β-diol, is an androstenediol that is converted to testosterone.

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5α-Dihydroethisterone

5α-Dihydroethisterone (5α-DHET; developmental code name HE-3562) is an active metabolite of the formerly clinically used but now-discontinued progestin ethisterone and the experimental and never-marketed hormonal antineoplastic agent ethynylandrostanediol (HE-3235).

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5α-Reductase inhibitor

5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss.

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7α-Thiomethylspironolactone

7α-Thiomethylspironolactone (7α-TMS; developmental code name SC-26519) is a steroidal antimineralocorticoid and antiandrogen of the spirolactone group and the major active metabolite of spironolactone.

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7α-Thioprogesterone

7α-Thioprogesterone (7α-TP4; developmental code name SC-8365; also known as 7α-mercaptopregn-4-ene-3,20-dione) is a synthetic, steroidal, and potent antimineralocorticoid (putative) and antiandrogen which was developed by G. D. Searle & Co and was described in the late 1970s and early 1980s but was never developed or introduced for medical use.

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7α-Thiospironolactone

7α-Thiospironolactone (7α-TS; developmental code name SC-24813; also known as deacetylspironolactone) is a steroidal antimineralocorticoid and antiandrogen of the spirolactone group and a minor active metabolite of spironolactone.

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References

[1] https://en.wikipedia.org/wiki/Antiandrogen

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