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CAPRISA 004

Index CAPRISA 004

CAPRISA 004 is the name of a clinical trial conducted by CAPRISA. [1]

8 relations: CAPRISA, CONRAD (organization), FHI 360, Microbicides for sexually transmitted diseases, Pre-exposure prophylaxis, Quarraisha Abdool Karim, Salim Abdool Karim, Vaginal microbicide.

CAPRISA

CAPRISA ("Centre for the AIDS Programme of Research in South Africa") is the name of an AIDS research center based in Durban, South Africa.

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CONRAD (organization)

CONRAD (Contraception Research and Development) is a non-profit organization scientific research organization that works to improve the reproductive health of women, especially in developing countries.

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FHI 360

FHI 360 (formerly Family Health International) is a nonprofit human development organization based in North Carolina.

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Microbicides for sexually transmitted diseases

Microbicides for sexually transmitted diseases are pharmacologic agents and chemical substances that are capable of killing or destroying certain microorganisms that commonly cause human infection (for example, the human immunodeficiency virus). Microbicides are a diverse group of chemical compounds that exert their activity by a variety of different mechanisms of action. Multiple compounds are being developed and tested for their microbicidal activity in clinical trials. Microbicides can be formulated in various delivery systems including gels, creams, lotions, aerosol sprays, tablets or films (which must be used near the time of sexual intercourse) and sponges and vaginal rings (or other devices that release the active ingredient(s) over a longer period). Some of these agents are being developed for vaginal application, and for rectal use by those engaging in anal sex. Although there are many approaches to preventing sexually transmitted diseases in general (and HIV in particular), current methods have not been sufficient to halt the spread of these diseases (particularly among women and people in less-developed nations). Sexual abstinence is not a realistic option for women who want to bear children, or who are at risk of sexual violence. In such situations, the use of microbicides could offer both primary protection (in the absence of condoms) and secondary protection (if a condom breaks or slips off during intercourse). It is hoped that microbicides may be safe and effective in reducing the risk of HIV transmission during sexual activity with an infected partner.

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Pre-exposure prophylaxis

Pre-exposure prophylaxis (PrEP) is the use of drugs to prevent disease in people who have not yet been exposed to the disease-causing agent.

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Quarraisha Abdool Karim

Quarraisha Abdool Karim is a South African epidemiologist who was awarded South Africa's highest honor, the Order of Mapungubwe (Bronze).

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Salim Abdool Karim

Professor Salim Safurdeen Abdool Karim is a South African epidemiologist and infectious diseases specialist.

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Vaginal microbicide

A vaginal microbicide is a microbicide for vaginal use.

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References

[1] https://en.wikipedia.org/wiki/CAPRISA_004

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