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Cholecystokinin A receptor

Index Cholecystokinin A receptor

The Cholecystokinin A receptor is a human protein, also known as CCKAR or CCK1, with CCK1 now being the IUPHAR-recommended name. [1]

12 relations: Asperlicin, CCK1, Cholecystokinin, Cholecystokinin antagonist, Cholecystokinin B receptor, Cholecystokinin receptor, Devazepide, Dexloxiglumide, Lorglumide, Orexin, Proglumide, Rhodopsin-like receptors.

Asperlicin

Asperlicin is a mycotoxin, derived from the fungus Aspergillus alliaceus.

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CCK1

CCK1 may refer to.

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Cholecystokinin

Cholecystokinin (CCK or CCK-PZ; from Greek chole, "bile"; cysto, "sac"; kinin, "move"; hence, move the bile-sac (gallbladder)) is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein.

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Cholecystokinin antagonist

A cholecystokinin antagonist is a specific type of receptor antagonist which blocks the receptor sites for the peptide hormone cholecystokinin (CCK).

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Cholecystokinin B receptor

The cholecystokinin B receptor also known as CCKBR or CCK2 is a protein that in humans is encoded by the CCKBR gene.

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Cholecystokinin receptor

Cholecystokinin receptors or CCK receptors are a group of G-protein coupled receptors which bind the peptide hormones cholecystokinin (CCK) and gastrin.

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Devazepide

Devazepide (L-364,718, MK-329) is benzodiazepine drug, but with quite different actions from most benzodiazepines, lacking affinity for GABAA receptors and instead acting as an CCKA receptor antagonist. It increases appetite and accelerates gastric emptying, and has been suggested as a potential treatment for a variety of gastrointestinal problems including dyspepsia, gastroparesis and gastric reflux.

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Dexloxiglumide

Dexloxiglumide is a drug which acts as a cholecystokinin antagonist, selective for the CCKA subtype.

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Lorglumide

Lorglumide (CR-1409) is a drug which inhibits gastrointestinal motility and reduces gastric secretions, acting as a cholecystokinin antagonist, with fairly high selectivity for the CCKA subtype. It has been suggested as a potential treatment for a variety of gastrointestinal problems including stomach ulcers, irritable bowel syndrome, dyspepsia, constipation and pancreatitis, as well as some forms of cancer, but animal and human testing has produced inconsistent results and no clear therapeutic role has been established, although it is widely used in scientific research.

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Orexin

Orexin, also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite.

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Proglumide

Proglumide (Milid) is a drug that inhibits gastrointestinal motility and reduces gastric secretions.

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Rhodopsin-like receptors

Rhodopsin-like receptors are a family of proteins that comprise the largest group of G protein-coupled receptors.

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Redirects here:

CCKAR, CCKAR (gene), Cholecystokinin a receptor.

References

[1] https://en.wikipedia.org/wiki/Cholecystokinin_A_receptor

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