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Chronic myelomonocytic leukemia

Index Chronic myelomonocytic leukemia

Chronic myelomonocytic leukaemia (CMML) is a type of leukaemia, which are cancers of the blood-forming cells of the bone marrow. [1]

38 relations: Cancer immunotherapy, Celgene, Chemotherapy, Clonal hypereosinophilia, CMML, Colony stimulating factor 1 receptor, Crenolanib, Decitabine, Dwayne Schintzius, Emberger syndrome, Eosinophilic myocarditis, ETV6, Fibroblast growth factor receptor 1, GATA2, GATA2 deficiency, Genesis P-Orridge, Glasdegib, Hypereosinophilia, Index of oncology articles, International Classification of Diseases for Oncology, Janus kinase inhibitor, Lenzilumab, Leukemia, List of acronyms: C, List of diseases (C), List of hematologic conditions, List of medical abbreviations: C, List of therapeutic monoclonal antibodies, Monocytic leukemia, Monocytosis, Myelodysplastic syndrome, Myelomonocyte, Panobinostat, Paul E. Meehl, PDGFRB, Rigosertib, Tet methylcytosine dioxygenase 2, Triciribine.

Cancer immunotherapy

Cancer immunotherapy (sometimes called immuno-oncology, abbreviated IO) is the use of the immune system to treat cancer.

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Celgene

Celgene Corporation is an American biotechnology company that discovers, develops and commercializes medicines for cancer and inflammatory disorders.

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Chemotherapy

Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.

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Clonal hypereosinophilia

Clonal hypereosinophilia, also termed primary hypereosinophilia or clonal eosinophilia, is a grouping of hematological disorders all of which are characterized by the development and growth of a pre-malignant or malignant population of eosinophils, a type of white blood cell that occupies the bone marrow, blood, and other tissues.

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CMML

CMML may refer to.

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Colony stimulating factor 1 receptor

Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded, in humans, by the CSF1R gene (known also as c-FMS).

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Crenolanib

Crenolanib besylate (CP-868,596-26 or AR-868,596-26, 4-piperidinamine, 1--, monobenzenesulfonate) is an investigational inhibitor being developed by AROG Pharmaceuticals, LLC.

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Decitabine

Decitabine (trade name Dacogen), or 5-aza-2'-deoxycytidine, acts as an Nucleic Acid Synthesis Inhibitor.

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Dwayne Schintzius

Dwayne Kenneth Schintzius (October 14, 1968 – April 15, 2012) was an American National Basketball Association (NBA) basketball player.

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Emberger syndrome

The Emberger syndrome is a rare, autosomal dominant, genetic disorder caused by familial or sporadic inactivating mutations in one of the two parental GATA2 genes.

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Eosinophilic myocarditis

Eosinophilic myocarditis is inflammation in the heart muscle that is caused by the infiltration and destructive activity of a type of white blood cell, the eosinophil.

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ETV6

ETV6 (i.e. translocation-Ets-leukemia virus) protein is a transcription factor that in humans is encoded by the ETV6 (previously known as TEL) gene.

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Fibroblast growth factor receptor 1

Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family.

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GATA2

GATA2 or GATA-binding factor 2 is a transcription factor, i.e. a nuclear protein which regulates the expression of genes.

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GATA2 deficiency

GATA2 deficiency (also termed GATA2 haploinsufficiency or GATA2 deficiency syndrome) is a recently defined grouping of several disorders caused by common defect, viz., familial or sporadic inactivating mutations in one of the two parental GATA2 genes.

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Genesis P-Orridge

Genesis Breyer P-Orridge (born Neil Andrew Megson; 22 February 1950) is an English singer-songwriter, musician, poet, performance artist, and occultist.

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Glasdegib

Glasdegib (PF-04449913) is an experimental cancer drug developed by Pfizer.

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Hypereosinophilia

Hypereosinophilia is an elevation in an individual's circulating blood eosinophil count above 15.0 x 109/L (i.e. 1,500/μL).

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Index of oncology articles

This is a list of terms related to oncology.

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International Classification of Diseases for Oncology

The International Classification of Diseases for Oncology (ICD-O) is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases.

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Janus kinase inhibitor

Janus kinase inhibitors, also known as JAK inhibitors or jakinibs, are a type of medication that functions by inhibiting the activity of one or more of the Janus kinase family of enzymes (JAK1, JAK2, JAK3, TYK2), thereby interfering with the JAK-STAT signaling pathway.

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Lenzilumab

Lenzilumab (INN) (alternative identifier KB003) is a humanized monoclonal antibody (class IgG1 kappa) that targets colony stimulating factor 2 (CSF2)/granulocyte-macrophage colony stimulating factor (GM-CSF) designed for the treatment of chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML).

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Leukemia

Leukemia, also spelled leukaemia, is a group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells.

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List of acronyms: C

(Main list of acronyms).

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List of diseases (C)

This is a list of diseases starting with the letter "C".

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List of hematologic conditions

There are many conditions of or affecting the human hematologic system — the biological system that includes plasma, platelets, leukocytes, and erythrocytes, the major components of blood and the bone marrow.

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List of medical abbreviations: C

Category:Lists of medical abbreviations.

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List of therapeutic monoclonal antibodies

This is a list of therapeutic, diagnostic and preventive monoclonal antibodies, antibodies that are clones of a single parent cell.

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Monocytic leukemia

Monocytic leukemia is a type of myeloid leukemia characterized by a dominance of monocytes in the marrow.

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Monocytosis

Monocytosis is an increase in the number of monocytes circulating in the blood.

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Myelodysplastic syndrome

Myelodysplastic syndromes (MDS) are a group of cancers in which immature blood cells in the bone marrow do not mature and therefore do not become healthy blood cells.

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Myelomonocyte

A myelomonocyte is a type of cell observed in chronic myelomonocytic leukemia.

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Panobinostat

Panobinostat (trade name Farydak) is a drug by Novartis for the treatment of various cancers.

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Paul E. Meehl

Paul Everett Meehl (3 January 1920 – 14 February 2003) was a clinical psychologist and Professor of Psychology at the University of Minnesota.

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PDGFRB

Beta-type platelet-derived growth factor receptor is a protein that in humans is encoded by the PDGFRB gene.

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Rigosertib

Rigosertib (ON-01910 sodium salt, with Estybon as trade name) is a synthetic benzyl styryl sulfone in development by Onconova Therapeutics.

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Tet methylcytosine dioxygenase 2

Tet methylcytosine dioxygenase 2 (TET2) is a human gene.

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Triciribine

Triciribine is a cancer drug which was first synthesized in the 1970s and studied clinically in the 1980s and 1990s without success.

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Chronic myelomonocytic leukaemia.

References

[1] https://en.wikipedia.org/wiki/Chronic_myelomonocytic_leukemia

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