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Drug reaction with eosinophilia and systemic symptoms

Index Drug reaction with eosinophilia and systemic symptoms

Drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), also termed drug-induced hypersensitivity syndrome (DIHS), is a rare reaction to certain medications. [1]

30 relations: Acute generalized exanthematous pustulosis, Allopurinol hypersensitivity syndrome, Anticonvulsant hypersensitivity syndrome, Carbamazepine, Dapsone, Dress (disambiguation), Drug allergy, Drug eruption, Drug intolerance, Eosinophilia, Eslicarbazepine acetate, Gabapentin, Hypereosinophilia, Lamotrigine, List of adverse effects of valproate semisodium, List of cutaneous conditions, List of syndromes, Minocycline, Modafinil, Nonsteroidal anti-inflammatory drug, NSAID hypersensitivity reactions, Severe cutaneous adverse reactions, Spironolactone, Stevens–Johnson syndrome, Strontium ranelate, Sulfonamide (medicine), Toxic epidermal necrolysis, Treatment of bipolar disorder, Vancomycin, Ziprasidone.

Acute generalized exanthematous pustulosis

Acute generalized exanthematous pustulosis (AGEP) (also known as pustular drug eruption and toxic pustuloderma) is a rare skin reaction that in 90% of cases is related to medication administration.

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Allopurinol hypersensitivity syndrome

Allopurinol hypersensitivity syndrome typically occurs in persons with preexisting kidney failure.

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Anticonvulsant hypersensitivity syndrome

Anticonvulsant/sulfonamide hypersensitivity syndrome is a potentially serious hypersensitivity reaction that can be seen with drugs with an aromatic amine chemical structure, such as aromatic anticonvulsants (e.g. diphenylhydantoin, phenobarbital, phenytoin, carbamazepine, lamotrigine), sulfonamides, or other drugs with an aromatic amine (procainamide).

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Carbamazepine

Carbamazepine (CBZ), sold under the tradename Tegretol, among others, is a medication used primarily in the treatment of epilepsy and neuropathic pain.

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Dapsone

Dapsone, also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy.

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Dress (disambiguation)

A dress is a garment consisting of a skirt with an attached bodice or with a matching bodice giving the effect of a one-piece garment.

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Drug allergy

A drug allergy is an allergy to a drug, most commonly a medication, and is a form of adverse drug reaction.

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Drug eruption

In medicine, a drug eruption is an adverse drug reaction of the skin.

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Drug intolerance

Drug intolerance or drug sensitivity refers to an inability to tolerate the adverse effects of a medication, generally at therapeutic or subtherapeutic doses.

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Eosinophilia

Eosinophilia is a condition in which the eosinophil count in the peripheral blood exceeds.

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Eslicarbazepine acetate

Eslicarbazepine acetate (trade names Aptiom in North America, Zebinix in Europe, Exalief in Russia, Eslicarba in Egypt), abbreviated as ESL, is an anticonvulsant medication approved for use in Europe and the United States as monotherapy or adjunctive therapy (additional therapy) for partial-onset seizures epilepsy.

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Gabapentin

Gabapentin, sold under the brand name Neurontin among others, is a medication which is used to treat epilepsy (specifically partial seizures), neuropathic pain, hot flashes, and restless legs syndrome.

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Hypereosinophilia

Hypereosinophilia is an elevation in an individual's circulating blood eosinophil count above 15.0 x 109/L (i.e. 1,500/μL).

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Lamotrigine

Lamotrigine, sold as the brand name Lamictal among others, is an anticonvulsant medication used to treat epilepsy and bipolar disorder.

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List of adverse effects of valproate semisodium

Adverse effects by frequency for use of valproate semisodium.

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List of cutaneous conditions

Many conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands.

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List of syndromes

This is an alphabetically-sorted list of medical syndromes.

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Minocycline

Minocycline is a broad-spectrum tetracycline antibiotic, and has a broader spectrum than the other members of the group.

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Modafinil

Modafinil, sold under the brand name Provigil among others, is a medication to treat sleepiness due to narcolepsy, shift work sleep disorder, or obstructive sleep apnea (OSA). In OSA continuous positive airway pressure is the preferred treatment. While it has seen off-label use as a purported cognitive enhancer, evidence for any benefit is lacking. It is taken by mouth. Common side effects include headache, anxiety, trouble sleeping, and nausea. Serious side effects may include allergic reactions such as anaphylaxis, Stevens–Johnson syndrome, abuse, or hallucinations. It is unclear if use during pregnancy is safe. The amount of medication used may need to be adjusted in those with kidney or liver problems. It is not recommended in those with an arrhythmia, significant hypertension, or left ventricular hypertrophy. How it works is not entirely clear. One possibility is that it may affect the areas of the brain involved with the sleep cycle. Modafinil was approved for medical use in the United States in 1998. In the United States it is classified as a schedule IV controlled substance due to concerns about addiction. In the United Kingdom it is a prescription only medication. It is avaliable as a generic medication. In the United Kingdom it costs the NHS about £105.21 a month as of 2018. In the United States the wholesale cost per month is about 34.20 USD as of 2018.

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Nonsteroidal anti-inflammatory drug

Nonsteroidal anti-inflammatory drugs (NSAIDs) are a drug class that reduce pain, decrease fever, prevent blood clots and, in higher doses, decrease inflammation.

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NSAID hypersensitivity reactions

NSAID or nonsteroidal anti-inflammatory drug hypersensitivity reactions encompasses a broad range of allergic or allergic-like symptoms that occur within minutes to hours after ingesting aspirin or other NSAID nonsteroidal anti-inflammatory drugs.

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Severe cutaneous adverse reactions

Severe cutaneous adverse reactions or SCARs are a group of potentially lethal adverse drug reactions that involve the skin and mucous membranes of various body openings such as the eyes, ears, and inside the nose, mouth, and lips.

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Spironolactone

Spironolactone, sold under the brand name Aldactone among others, is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.

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Stevens–Johnson syndrome

Stevens–Johnson syndrome (SJS) is a type of severe skin reaction.

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Strontium ranelate

Strontium ranelate, a strontium(II) salt of ranelic acid, is a medication for osteoporosis marketed as Protelos or Protos by Servier.

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Sulfonamide (medicine)

Sulfonamide (also called sulphonamide, sulfa drugs or sulpha drugs) is the basis of several groups of drugs.

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Toxic epidermal necrolysis

Toxic epidermal necrolysis (TEN) is a type of severe skin reaction.

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Treatment of bipolar disorder

The emphasis of the treatment of bipolar disorder is on effective management of the long-term course of the illness, which can involve treatment of emergent symptoms.

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Vancomycin

Vancomycin is an antibiotic used to treat a number of bacterial infections.

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Ziprasidone

Ziprasidone, sold under the brand name Geodon among others, is an atypical antipsychotic which is used for the treatment of schizophrenia as well as acute mania and mixed states associated with bipolar disorder.

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DRESS syndrome, Drug Rash with Eosinophilia and Systemic Symptoms, Drug Reaction with Eosinophilia and Systemic Symptoms, Drug hypersensitivity syndrome, Drug rash with eosinophilia and systemic symptoms.

References

[1] https://en.wikipedia.org/wiki/Drug_reaction_with_eosinophilia_and_systemic_symptoms

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