Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Androidâ„¢ device!
Download
Faster access than browser!
 

Epoxyeicosatrienoic acid

Index Epoxyeicosatrienoic acid

The epoxyeicosatrienoic acids or EETs are signaling molecules formed within various types of cells by the metabolism of arachidonic acid by a specific subset of Cytochrome P450 enzymes termed cytochrome P450 epoxygenases. [1]

30 relations: Arachidonic acid, C20H32O3, Coronaric acid, CYP2C18, CYP2C19, CYP2C8, CYP2C9, CYP2J2, CYP2S1, CYP3A4, CYP4F3, Docosanoid, Docosatetraenoic acid, EET, Eicosanoid, Endothelium-derived hyperpolarizing factor, Epoxide, Epoxide hydrolase, Epoxide hydrolase 2, Epoxide hydrolase 3, Epoxydocosapentaenoic acid, Epoxyeicosatetraenoic acid, Epoxygenase, Essential fatty acid, Essential fatty acid interactions, Monooxygenase, Nonclassic eicosanoid, Regorafenib, TRPA1, 20-Hydroxyeicosatetraenoic acid.

Arachidonic acid

Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6).

New!!: Epoxyeicosatrienoic acid and Arachidonic acid · See more »

C20H32O3

The molecular formula C20H32O3 may refer to.

New!!: Epoxyeicosatrienoic acid and C20H32O3 · See more »

Coronaric acid

Coronaric acid (isoleukotoxin) is a mono-unsaturated, epoxide derivative of the di-saturated fatty acid, linoleic acid (i.e. 9(Z),12(Z) octadecadienoic acid. It is a mixture of the two optically active isomers of 12(Z) 9,10-epoxy-octadecenoic acid. This mixture is also termed 9,10-epoxy-12Z-octadecenoic acid or 9(10)-EpOME and when formed by or studied in mammalians, isoleukotoxin.

New!!: Epoxyeicosatrienoic acid and Coronaric acid · See more »

CYP2C18

Cytochrome P450 2C18 is a protein that in humans is encoded by the CYP2C18 gene.

New!!: Epoxyeicosatrienoic acid and CYP2C18 · See more »

CYP2C19

Cytochrome P450 2C19 (abbreviated CYP2C19) is an enzyme.

New!!: Epoxyeicosatrienoic acid and CYP2C19 · See more »

CYP2C8

Cytochrome P4502C8 (abbreviated CYP2C8), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body.

New!!: Epoxyeicosatrienoic acid and CYP2C8 · See more »

CYP2C9

Cytochrome P450 2C9 (abbreviated CYP2C9) is an enzyme that in humans is encoded by the CYP2C9 gene.

New!!: Epoxyeicosatrienoic acid and CYP2C9 · See more »

CYP2J2

Cytochrome P450 2J2 (CYP2J2) is a protein that in humans is encoded by the CYP2J2 gene.

New!!: Epoxyeicosatrienoic acid and CYP2J2 · See more »

CYP2S1

Cytochrome P450 2S1 is a protein that in humans is encoded by the CYP2S1 gene.

New!!: Epoxyeicosatrienoic acid and CYP2S1 · See more »

CYP3A4

Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.

New!!: Epoxyeicosatrienoic acid and CYP3A4 · See more »

CYP4F3

Leukotriene-B(4) omega-hydroxylase 2 is an enzyme that in humans is encoded by the CYP4F3 gene.

New!!: Epoxyeicosatrienoic acid and CYP4F3 · See more »

Docosanoid

In biochemistry, docosanoids are signaling molecules made by the metabolism of twenty-two-carbon fatty acids (EFAs), especially the omega-3 fatty acid, Docosahexaenoic acid (DHA) (i.e. 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid) by lipoxygenase, cyclooxygenase, and cytochrome P450 enzymes.

New!!: Epoxyeicosatrienoic acid and Docosanoid · See more »

Docosatetraenoic acid

Docosatetraenoic acid designates any straight chain 22:4 fatty acid.

New!!: Epoxyeicosatrienoic acid and Docosatetraenoic acid · See more »

EET

EET or eet may refer to.

New!!: Epoxyeicosatrienoic acid and EET · See more »

Eicosanoid

Eicosanoids are signaling molecules made by the enzymatic or non-enzymatic oxidation of arachidonic acid or other polyunsaturated fatty acids (PUFAs) that are, similar to arachidonic acid, 20 carbon units in length.

New!!: Epoxyeicosatrienoic acid and Eicosanoid · See more »

Endothelium-derived hyperpolarizing factor

In blood vessels Endothelium-Derived Hyperpolarizing Factor or EDHF is proposed to be a substance and/or electrical signal that is generated or synthesized in and released from the endothelium; its action is to hyperpolarize vascular smooth muscle cells, causing these cells to relax, thus allowing the blood vessel to expand in diameter.

New!!: Epoxyeicosatrienoic acid and Endothelium-derived hyperpolarizing factor · See more »

Epoxide

An epoxide is a cyclic ether with a three-atom ring.

New!!: Epoxyeicosatrienoic acid and Epoxide · See more »

Epoxide hydrolase

Epoxide hydrolases (EH's), also known as epoxide hydratases, are enzymes that metabolize compounds that contain an epoxide residue; they convert this residue to two hydroxyl residues through a dihydroxylation reaction to form diol products.

New!!: Epoxyeicosatrienoic acid and Epoxide hydrolase · See more »

Epoxide hydrolase 2

Soluble epoxide hydrolase (sEH) is a bifunctional enzyme that in humans is encoded by the EPHX2 gene.

New!!: Epoxyeicosatrienoic acid and Epoxide hydrolase 2 · See more »

Epoxide hydrolase 3

Epoxide hydrolase 3 (ABHD9, EH3, EPHX3), encoded by the EPHX3 gene, is the third defined isozyme in a set of epoxide hydrolase isozymes, i.e. the epoxide hydrolases.

New!!: Epoxyeicosatrienoic acid and Epoxide hydrolase 3 · See more »

Epoxydocosapentaenoic acid

Epoxide docosapentaenoic acids (epoxydocosapentaenoic acids, EDPs, or EpDPEs) are metabolites of the 22-carbon straight-chain omega-3 fatty acid, docosahexaenoic acid (DHA).

New!!: Epoxyeicosatrienoic acid and Epoxydocosapentaenoic acid · See more »

Epoxyeicosatetraenoic acid

Epoxyeicosatetraenoic acids (EEQs or EpETEs) are a set of biologically active epoxides that various cell types make by metabolizing the omega 3 fatty acid, eicosapentaenoic acid (EPA), with certain cytochrome P450 epoxygenases.

New!!: Epoxyeicosatrienoic acid and Epoxyeicosatetraenoic acid · See more »

Epoxygenase

Epoxygenases are a set of membrane-bound, heme-containing cytochrome P450 (CYP P450 or just CYP) enzymes that metabolize polyunsaturated fatty acids to epoxide products that have a range of biological activities.

New!!: Epoxyeicosatrienoic acid and Epoxygenase · See more »

Essential fatty acid

Essential fatty acids, or EFAs, are fatty acids that humans and other animals must ingest because the body requires them for good health but cannot synthesize them.

New!!: Epoxyeicosatrienoic acid and Essential fatty acid · See more »

Essential fatty acid interactions

The effects on humans of the ω-3 (omega-3) and ω-6 (omega-6) essential fatty acids (EFAs) are best characterized by their interactions; they cannot be understood separately.

New!!: Epoxyeicosatrienoic acid and Essential fatty acid interactions · See more »

Monooxygenase

Monooxygenases are enzymes that incorporate one hydroxyl group into substrates in many metabolic pathways.

New!!: Epoxyeicosatrienoic acid and Monooxygenase · See more »

Nonclassic eicosanoid

Nonclassic eicosanoids are biologically active signaling molecules made by oxygenation of twenty-carbon fatty acids other than the classic eicosanoids.

New!!: Epoxyeicosatrienoic acid and Nonclassic eicosanoid · See more »

Regorafenib

Regorafenib (BAY 73-4506, commercial name Stivarga) is an oral multi-kinase inhibitor developed by Bayer which targets angiogenic, stromal and oncogenic receptor tyrosine kinase (RTK).

New!!: Epoxyeicosatrienoic acid and Regorafenib · See more »

TRPA1

Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1 or TRPA1, is a protein that in humans is encoded by the TRPA1 (and in other species by the Trpa1) gene.

New!!: Epoxyeicosatrienoic acid and TRPA1 · See more »

20-Hydroxyeicosatetraenoic acid

20-Hydroxyeicosatetraenoic acid, also known as 20-HETE or 20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid, is an eicosanoid metabolite of arachidonic acid that has a wide range of effects on the vascular system including the regulation of vascular tone, blood flow to specific organs, sodium and fluid transport in the kidney, and vascular pathway remodeling.

New!!: Epoxyeicosatrienoic acid and 20-Hydroxyeicosatetraenoic acid · See more »

Redirects here:

12S-HETE, 12S-HpETE, 4,5-EET, 5',6'-Epoxyeicosatrienoic acid, Eicosatrienoic acid epoxide, Epoxyeicosatrienoic acids.

References

[1] https://en.wikipedia.org/wiki/Epoxyeicosatrienoic_acid

OutgoingIncoming
Hey! We are on Facebook now! »