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95 relations: ADA (buffer), Alcohol intoxication, Alcohol withdrawal syndrome, Allodynia, Alprazolam, Automated patch clamp, Bamaluzole, Binaural fusion, Burst suppression, Camazepam, Cerebral cortex, CGS-13767, Chloral hydrate, Chloride potassium symporter 5, CI-966, Cicutoxin, Collybistin, Devazepide, Developmental plasticity, Dihydropicrotoxinin, Endosulfan, Epilepsy, Erminio Costa, Eszopiclone, Fengabine, Fipronil, Fleroxacin, Flunitrazepam, GABA (disambiguation), GABA receptor agonist, GABAA receptor, GABAA receptor positive allosteric modulator, GABAB receptor, Gabapentin, Gabapentinoid, GABRA3, Gamma-Aminobutyric acid, Gamma-Hydroxybutyric acid, Generalized epilepsy with febrile seizures plus, Gerhard Ecker, Hyperforin, Hyperkinesia, Idiopathic generalized epilepsy, Idiopathic hypersomnia, Illicium verum, Index of biochemistry articles, Ion channel, Ionotropic GABA receptor, Isoflurane, Juvenile myoclonic epilepsy, ..., JWH-018, Lanthanum, Laudanosine, List of MeSH codes (D12.776.543), Lorazepam, Lormetazepam, Losigamone, Low-dose naltrexone, Mesolimbic pathway, Methaqualone, Molecular neuroscience, Morphine-3-glucuronide, Mossy fiber (hippocampus), Narcolepsy, Neurexin, Neurotransmitter, Neurotransmitter receptor, North West England, Nucleus accumbens, Paresthesia, Paroxysmal sympathetic hyperactivity, Picamilon, Piperazine, Plant perception (physiology), Postictal state, Pregabalin, Receptor (biochemistry), Reward system, Rhombic lip, Ropinirole, Status epilepticus, Sunifiram, Thalamocortical radiations, Thiomuscimol, Thujone, Tolgabide, Toluene toxicity, Transgender hormone therapy (male-to-female), Ultrasonic vocalization, Unifiram, Valerian (herb), Vigabatrin, Wynn's propulsion effect, Zaleplon, (Z)-4-Amino-2-butenoic acid. Expand index (45 more) »
ADA (buffer)
ADA is a zwitterionic organic chemical buffering agent; one of Good's buffers.
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Alcohol intoxication
Alcohol intoxication, also known as drunkenness or alcohol poisoning, is negative behavior and physical effects due to the recent drinking of ethanol (alcohol).
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Alcohol withdrawal syndrome
Alcohol withdrawal syndrome is a set of symptoms that can occur following a reduction in alcohol use after a period of excessive use.
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Allodynia
Allodynia (Ancient Greek άλλος állos "other" and οδύνη odúnē "pain") refers to central pain sensitization (increased response of neurons) following normally non-painful, often repetitive, stimulation.
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Alprazolam
Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer.
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Automated patch clamp
Automated patch clamping is beginning to replace manual patch clamping as a method to measure the electrical activity of individual cells.
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Bamaluzole
Bamaluzole is a GABA receptor agonist.
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Binaural fusion
Binaural fusion or binaural integration is a cognitive process that involves the "fusion" of different auditory information presented binaurally, or to each ear.
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Burst suppression
Burst suppression is an electroencephalography (EEG) pattern that is characterized by periods of high-voltage electrical activity alternating with periods of no activity in the brain.
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Camazepam
Camazepam is a benzodiazepine psychoactive drug, marketed under the brand names Albego, Limpidon and Paxor.
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Cerebral cortex
The cerebral cortex is the largest region of the cerebrum in the mammalian brain and plays a key role in memory, attention, perception, cognition, awareness, thought, language, and consciousness.
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CGS-13767
CGS-13767 is an anxiolytic GABA receptor ligand.
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Chloral hydrate
Chloral hydrate is a geminal diol with the formula C2H3Cl3O2.
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Chloride potassium symporter 5
Potassium-chloride transporter member 5 (aka: KCC2 and SLC12A5) is a neuron-specific chloride potassium symporter responsible for establishing the chloride ion gradient in neurons through the maintenance of low intracellular chloride concentrations.
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CI-966
CI-966 (developmental code name) is a central nervous system depressant acting as a GABA reuptake inhibitor, specifically a highly potent and selective blocker of the GABA transporter 1 (GAT-1) (IC50.
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Cicutoxin
Cicutoxin is a poisonous polyyne and alcohol found in various plants, such as the highly toxic water hemlock (Cicuta species).
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Collybistin
Collybistin is a protein identified as a regulator of the localization of gephyrin, inducing the formation of submembrane gephyrin aggregates that accumulate glycine and GABA receptors.
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Devazepide
Devazepide (L-364,718, MK-329) is benzodiazepine drug, but with quite different actions from most benzodiazepines, lacking affinity for GABAA receptors and instead acting as an CCKA receptor antagonist. It increases appetite and accelerates gastric emptying, and has been suggested as a potential treatment for a variety of gastrointestinal problems including dyspepsia, gastroparesis and gastric reflux.
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Developmental plasticity
Developmental plasticity is a general term referring to changes in neural connections during development as a result of environmental interactions as well as neural changes induced by learning.
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Dihydropicrotoxinin
Dihydropicrotoxinin is the saturated derivative of picrotoxinin.
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Endosulfan
Endosulfan is an off-patent organochlorine insecticide and acaricide that is being phased out globally.
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Epilepsy
Epilepsy is a group of neurological disorders characterized by epileptic seizures.
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Erminio Costa
Erminio "Mimo" Costa (March 9, 1924 – November 28, 2009) was an Italian-American neuroscientist.
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Eszopiclone
Eszopiclone, marketed by Sunovion under the brand-name Lunesta, is a nonbenzodiazepine hypnotic agent used in the treatment of insomnia.
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Fengabine
Fengabine (SL-79,229) is a drug which was investigated as an antidepressant but was never marketed.
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Fipronil
Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole chemical family.
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Fleroxacin
Fleroxacin is a quinolone antibiotic.
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Flunitrazepam
Flunitrazepam, also known as Rohypnol among other names, is an intermediate acting benzodiazepine used in some countries to treat severe insomnia and in fewer, early in anesthesia.
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GABA (disambiguation)
GABA may refer to.
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GABA receptor agonist
A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects.
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GABAA receptor
The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.
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GABAA receptor positive allosteric modulator
In pharmacology, GABAA receptor positive allosteric modulators are positive allosteric modulator (PAM) molecules that increase the activity of the GABAA receptor protein in the vertebrate central nervous system.
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GABAB receptor
GABAB receptors (GABABR) are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA) that are linked via G-proteins to potassium channels.
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Gabapentin
Gabapentin, sold under the brand name Neurontin among others, is a medication which is used to treat epilepsy (specifically partial seizures), neuropathic pain, hot flashes, and restless legs syndrome.
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Gabapentinoid
Gabapentinoids, also known as α2δ ligands, are a class of drugs that are derivatives of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) (i.e., GABA analogues) which block α2δ subunit-containing voltage-dependent calcium channels (VDCCs).
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GABRA3
Gamma-aminobutyric acid receptor subunit alpha-3 is a protein that in humans is encoded by the GABRA3 gene.
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Gamma-Aminobutyric acid
gamma-Aminobutyric acid, or γ-aminobutyric acid, or GABA, is the chief inhibitory neurotransmitter in the mammalian central nervous system.
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Gamma-Hydroxybutyric acid
γ-Hydroxybutyric acid (GHB), also known as 4-hydroxybutanoic acid, is a naturally occurring neurotransmitter and a psychoactive drug.
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Generalized epilepsy with febrile seizures plus
Generalized epilepsy with febrile seizures plus (GEFS+) is a syndromic autosomal dominant disorder where afflicted individuals can exhibit numerous epilepsy phenotypes.
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Gerhard Ecker
Gerhard F. Ecker is an Austrian medicinal chemist and expert in the fields of Pharmacoinformatics at the University of Vienna.
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Hyperforin
Hyperforin is a phytochemical produced by some of the members of the plant genus Hypericum, notably Hypericum perforatum (St John's wort).
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Hyperkinesia
Hyperkinesia, also known as hyperkinesis, refers to an increase in muscular activity that can result in excessive abnormal movements, excessive normal movements, or a combination of both.
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Idiopathic generalized epilepsy
Idiopathic generalized epilepsy (IGE) is a group of epileptic disorders that are believed to have a strong underlying genetic basis.
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Idiopathic hypersomnia
Idiopathic hypersomnia is a neurological disorder which is characterized primarily by excessive daytime sleepiness (EDS).
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Illicium verum
Illicium verum is a medium-sized evergreen tree native to northeast Vietnam and southwest China.
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Index of biochemistry articles
Biochemistry is the study of the chemical processes in living organisms.
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Ion channel
Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore.
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Ionotropic GABA receptor
Ionotropic GABA receptors (iGABARs) are ligand-gated ion channel GABA receptors and include.
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Isoflurane
Isoflurane, sold under the trade name Forane among others, is a general anesthetic.
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Juvenile myoclonic epilepsy
Juvenile myoclonic epilepsy (JME), also known as Janz syndrome, is a fairly common form of idiopathic generalized epilepsy, representing 5-10% of all epilepsy cases.
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JWH-018
JWH-018 (1-pentyl-3-(1-naphthoyl)indole) or AM-678 is an analgesic chemical from the naphthoylindole family that acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, with some selectivity for CB2.
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Lanthanum
Lanthanum is a chemical element with symbol La and atomic number 57.
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Laudanosine
Laudanosine or N-methyltetrahydropapaverine is a recognized metabolite of atracurium and cisatracurium.
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List of MeSH codes (D12.776.543)
This is a sub-part (membrane proteins only) of List of MeSH codes (D12.776), itself a part of the list of the "D" codes for MeSH.
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Lorazepam
Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication.
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Lormetazepam
Lormetazepam (INN), or methyl-lorazepam, marketed as Noctamid among others, is a drug which is a short to intermediate acting 3-hydroxy benzodiazepine derivative.
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Losigamone
Losigamone (INN) is an investigational drug for the treatment of epilepsy.
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Low-dose naltrexone
Low-dose naltrexone (LDN) describes the off-label use of the medication naltrexone at low doses for diseases such as Crohn's disease and multiple sclerosis.
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Mesolimbic pathway
The mesolimbic pathway, sometimes referred to as the reward pathway, is a dopaminergic pathway in the brain.
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Methaqualone
Methaqualone, sold under the brand name Quaalude (pronounced) and sometimes stylized "Quāālude" in the United States and Mandrax in the United Kingdom and South Africa, is a sedative and hypnotic medication.
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Molecular neuroscience
Molecular neuroscience is a branch of neuroscience that observes concepts in molecular biology applied to the nervous systems of animals.
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Morphine-3-glucuronide
Morphine-3-glucuronide is a metabolite of morphine produced by UGT2B7.
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Mossy fiber (hippocampus)
In the hippocampus, the mossy fiber pathway consists of unmyelinated axons projecting from granule cells in the dentate gyrus that terminate on modulatory hilar mossy cells and in Cornu Ammonis area 3 (CA3), a region involved in encoding short-term memory.
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Narcolepsy
Narcolepsy is a long-term neurological disorder that involves a decreased ability to regulate sleep-wake cycles.
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Neurexin
Neurexin (NRXN) is a presynaptic protein that helps to connect neurons at the synapse.
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Neurotransmitter
Neurotransmitters are endogenous chemicals that enable neurotransmission.
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Neurotransmitter receptor
A neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is activated by a neurotransmitter.
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North West England
North West England, one of nine official regions of England, consists of the five counties of Cheshire, Cumbria, Greater Manchester, Lancashire and Merseyside.
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Nucleus accumbens
The nucleus accumbens (NAc or NAcc), also known as the accumbens nucleus, or formerly as the nucleus accumbens septi (Latin for nucleus adjacent to the septum) is a region in the basal forebrain rostral to the preoptic area of the hypothalamus.
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Paresthesia
Paresthesia is an abnormal sensation such as tingling, tickling, pricking, numbness or burning of a person's skin with no apparent physical cause.
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Paroxysmal sympathetic hyperactivity
Paroxysmal sympathetic hyperactivity (PSH) is a syndrome that causes episodes of increased activity of the sympathetic nervous system.
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Picamilon
Picamilon (also known as N-nicotinoyl-GABA, pycamilon, and pikamilon) is a drug formed by a synthetic combination of niacin and GABA.
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Piperazine
Piperazine is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring.
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Plant perception (physiology)
Plant perception is the ability of plants to sense and respond to the environment to adjust their morphology, physiology, and phenotype accordingly.
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Postictal state
The postictal state is the altered state of consciousness after an epileptic seizure.
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Pregabalin
Pregabalin, marketed under the brand name Lyrica among others, is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder.
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Receptor (biochemistry)
In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.
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Reward system
The reward system is a group of neural structures responsible for incentive salience (i.e., motivation and "wanting", desire, or craving for a reward), associative learning (primarily positive reinforcement and classical conditioning), and positive emotions, particularly ones which involve pleasure as a core component (e.g., joy, euphoria and ecstasy).
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Rhombic lip
The rhombic lip is a posterior section of the developing metencephalon which can be recognized transiently within the vertebrate embryo.
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Ropinirole
Ropinirole (INN; trade names Requip, Repreve, Ronirol, Adartrel) is a dopamine agonist of the non-ergoline class of medications.
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Status epilepticus
Status epilepticus (SE) is a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to normal between them.
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Sunifiram
Sunifiram (developmental code name DM-235) is an experimental drug which has antiamnesic effects in animal studies and with significantly higher potency than piracetam.
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Thalamocortical radiations
Thalamocortical radiations are the fibers between the thalamus and the cerebral cortex.
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Thiomuscimol
Thiomuscimol is a GABAA receptor agonist which is structurally related to muscimol.
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Thujone
No description.
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Tolgabide
Tolgabide INN (SL-81.0142) is a drug which was patented by Synthélabo as an anticonvulsant but was never marketed.
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Toluene toxicity
Toluene toxicity refers to the harmful effects caused by toluene on the body.
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Transgender hormone therapy (male-to-female)
Transgender hormone therapy of the male-to-female (MTF) type, also known as feminizing hormone therapy, is a form of hormone replacement therapy (HRT) and sex reassignment therapy which is used to change the secondary sexual characteristics of transgender people from masculine (or androgynous) to feminine.
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Ultrasonic vocalization
Ultrasonic vocalizations (USVs) occur at frequencies ranging from approximately 20–100 kHz.
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Unifiram
Unifiram (developmental code name DM-232) is an experimental drug.
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Valerian (herb)
Valerian (Valeriana officinalis, Caprifoliaceae) is a perennial flowering plant native to Europe and Asia.
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Vigabatrin
Vigabatrin, brand name Sabril, is an antiepileptic drug that inhibits the breakdown of γ-aminobutyric acid (GABA) by acting as a suicide inhibitor of the enzyme GABA transaminase (GABA-T).
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Wynn's propulsion effect
Wynn's Propulsion Effect is a thermodynamic force exerted on the plasma membrane of the cardiovascular tissue of amphibians, particularly notable with the toad, Bufo marinus.
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Zaleplon
Zaleplon (marketed under the brand names Sonata, Starnoc, and Andante) is a sedative-hypnotic, almost entirely used for the management/treatment of insomnia.
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(Z)-4-Amino-2-butenoic acid
(Z)-4-Amino-2-butenoic acid (CACA, cis-4-aminocrotonic acid) is a GABA receptor partial agonist selective for the GABAA-ρ (previously known as GABAC) subtype.
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GABA receptors, GABA-A receptors, GABAR, Gaba receptor, Gaba receptors, Receptors, gaba.
References
[1] https://en.wikipedia.org/wiki/GABA_receptor
