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GABA transporter 1

Index GABA transporter 1

GABA transporter 1 (GAT1) also known as sodium- and chloride-dependent GABA transporter 1 is a protein that in humans is encoded by the SLC6A1 gene. [1]

17 relations: Chandelier cell, CI-966, GABA transporter, GABA transporter type 2, GABA transporter type 3, GAT, Nathan Nelson, Neuronal lineage marker, Neurotransmitter sodium symporter, Neurotransmitter transporter, NNC-711, Norepinephrine transporter, Schizophrenia, SKF-89976A, Solute carrier family, STX1A, Tiagabine.

Chandelier cell

Chandelier neurons or chandelier cells are a subset of GABA-ergic cortical interneurons.

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CI-966

CI-966 (developmental code name) is a central nervous system depressant acting as a GABA reuptake inhibitor, specifically a highly potent and selective blocker of the GABA transporter 1 (GAT-1) (IC50.

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GABA transporter

GABA transporters are neurotransmitter transporters including.

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GABA transporter type 2

GABA transporter 2 (GAT2; SLC6A13) also known as sodium- and chloride-dependent GABA transporter 2 is one of four GABA transporters, GAT1 (SLC6A1), GAT2 (SLC6A13), GAT3 (SLC6A11) and BGT1 (SLC6A12).

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GABA transporter type 3

GABA transporter type 3 (GAT3) uses sodium (Na+) electrochemical gradients to mediate uptake of GABA from the synaptic cleft by surrounding glial cells.

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GAT

Gat or GAT may refer to.

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Nathan Nelson

Nathan Nelson is a biochemist and molecular biologist who was awarded the 2013 Israel Prize in Life Sciences.

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Neuronal lineage marker

A Neuronal lineage marker is an endogenous tag that is expressed in different cells along neurogenesis and differentiated cells such as neurons.

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Neurotransmitter sodium symporter

Members of the Neurotransmitter:Sodium Symporter (NSS) family catalyze uptake of a variety of neurotransmitters, amino acids, osmolytes and related nitrogenous substances by a solute:Na+ symport mechanism.

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Neurotransmitter transporter

Neurotransmitter transporters are a class of membrane transport proteins that span the cellular membranes of neurons.

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NNC-711

NNC-711 is an anticonvulsant, acting as a gamma-aminobutyric acid uptake inhibitor via inhibition of GAT-1.

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Norepinephrine transporter

The norepinephrine transporter (NET), also known as solute carrier family 6 member 2 (SLC6A2), is a protein that in humans is encoded by the SLC6A2 gene.

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Schizophrenia

Schizophrenia is a mental disorder characterized by abnormal social behavior and failure to understand reality.

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SKF-89976A

SKF-89976A is an anticonvulsant, acting as a GABA reuptake inhibitor via blockade of GAT-1.

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Solute carrier family

The solute carrier (SLC) group of membrane transport proteins include over 400 members organized into 65 families.

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STX1A

Syntaxin-1A is a protein that in humans is encoded by the STX1A gene.

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Tiagabine

Tiagabine (trade name Gabitril) is an anticonvulsant medication used in the treatment of epilepsy that is produced by Cephalon.

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Redirects here:

GABA transporter type 1, GAT-1, SLC6A1, SLC6A1 (gene).

References

[1] https://en.wikipedia.org/wiki/GABA_transporter_1

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