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Glucokinase

Index Glucokinase

Glucokinase is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. [1]

46 relations: Actin-binding protein, Andrew Hattersley, Beta cell, Chemical specificity, Congenital hyperinsulinism, Deinococcus marmoris, Enzyme, Enzyme activator, Ernesto Bustamante, Fructokinase, Fructolysis, GCK, GK, GLK, Glucokinase regulatory protein, Gluconeogenesis, Glucose 6-phosphate, Glucose cycle, GLUT4, Glutamate dehydrogenase 1, Glycogenesis, Glycolysis, Hexokinase, HK1, HK2, HK3, HKDC1, Hyperinsulinemic hypoglycemia, Inborn errors of carbohydrate metabolism, Insulin, Isozyme, Lipogenesis, List of EC numbers (EC 2), List of MeSH codes (D08), List of OMIM disorder codes, Mannoheptulose, Maturity onset diabetes of the young, MODY 2, Nesfatin-1, NFE2L1, Nutriepigenomics, Permanent neonatal diabetes mellitus, Propionyl-CoA carboxylase, Tagatose, Voltage-dependent anion channel, 1,5-Anhydroglucitol.

Actin-binding protein

Actin-binding protein (also known as ABP) are proteins that bind to actin.

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Andrew Hattersley

Andrew Tym Hattersley CBE FRS (born 1958, London) is a Professor of Molecular Medicine at the University of Exeter and is known for his research in monogenic diabetes.

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Beta cell

Beta cells (β cells) are a type of cell found in the pancreatic islets of the pancreas.

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Chemical specificity

Chemical specificity is the ability of a protein's binding site to bind specific ligands.

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Congenital hyperinsulinism

Congenital hyperinsulinism,CHI, is a medical term referring to a variety of congenital disorders in which hypoglycemia is caused by excessive insulin secretion.

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Deinococcus marmoris

Deinococcus marmoris is a Gram-positive bacterium isolated from Antarctica.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Enzyme activator

Enzyme activators are molecules that bind to enzymes and increase their activity.

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Ernesto Bustamante

Ernesto Bustamante (born May 19, 1950 in Lima, Peru) is a scientist known for his expertise and contributions to the field of molecular biology.

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Fructokinase

Fructokinase (/fruc•to•ki•nase/), also known as D-fructokinase or D-fructose (D-mannose) kinase,.

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Fructolysis

Fructolysis refers to the metabolism of fructose from dietary sources.

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GCK

GCK may refer to.

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GK

GK or Gk may refer to.

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GLK

GLK may refer to.

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Glucokinase regulatory protein

The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in hepatocytes (liver cells).

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Gluconeogenesis

Gluconeogenesis (GNG) is a metabolic pathway that results in the generation of glucose from certain non-carbohydrate carbon substrates.

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Glucose 6-phosphate

Glucose 6-phosphate (sometimes called the Robison ester) is a glucose sugar phosphorylated at the hydroxy group on carbon 6.

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Glucose cycle

The glucose cycle (also known as the hepatic futile cycle) occurs primarily in the liver and is the dynamic balance between glucose and glucose 6-phosphate.

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GLUT4

Glucose transporter type 4 (GLUT-4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the SLC2A4 gene.

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Glutamate dehydrogenase 1

GLUD1 (glutamate dehydrogenase 1) is a mitochondrial matrix enzyme, one of the family of glutamate dehydrogenases that are ubiquitous in life, with a key role in nitrogen and glutamate (Glu) metabolism and energy homeostasis.

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Glycogenesis

Glycogenesis is the process of glycogen synthesis, in which glucose molecules are added to chains of glycogen for storage.

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Glycolysis

Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+.

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Hexokinase

A hexokinase is an enzyme that phosphorylates hexoses (six-carbon sugars), forming hexose phosphate.

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HK1

Hexokinase-1 (HK1) is an enzyme that in humans is encoded by the HK1 gene on chromosome 10.

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HK2

Hexokinase 2 also known as HK2 is an enzyme which in humans is encoded by the HK2 gene on chromosome 2.

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HK3

Hexokinase 3 also known as HK3 is an enzyme which in humans is encoded by the HK2 gene on chromosome 5.

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HKDC1

Hexokinase domain containing 1 (HKDC1) is an enzyme which in humans is encoded by the HKDC1 gene on chromosome 10.

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Hyperinsulinemic hypoglycemia

Hyperinsulinemic hypoglycemia describes the condition and effects of low blood glucose caused by excessive insulin.

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Inborn errors of carbohydrate metabolism

Inborn errors of carbohydrate metabolism are inborn error of metabolism that affect the catabolism and anabolism of carbohydrates.

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Insulin

Insulin (from Latin insula, island) is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body.

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Isozyme

Isozymes (also known as isoenzymes or more generally as multiple forms of enzymes) are enzymes that differ in amino acid sequence but catalyze the same chemical reaction.

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Lipogenesis

Lipogenesis is the process by which acetyl-CoA is converted to fatty acids.

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List of EC numbers (EC 2)

This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.

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List of MeSH codes (D08)

This is the fourth part of the list of the "D" codes for MeSH.

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List of OMIM disorder codes

This is a list of disorder codes in the Online Mendelian Inheritance in Man (OMIM) database.

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Mannoheptulose

Mannoheptulose is a heptose, a monosaccharide with seven carbon atoms, and a ketose, with the characteristic carbonyl group of the carbohydrate present on a secondary carbon (functioning as a ketone group).

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Maturity onset diabetes of the young

"Maturity onset diabetes of the young" (MODY) refers to any of several hereditary forms of diabetes mellitus caused by mutations in an autosomal dominant gene disrupting insulin production.

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MODY 2

MODY 2 is a form of maturity onset diabetes of the young.

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Nesfatin-1

Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals.

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NFE2L1

Nuclear factor erythroid 2-related factor 1 (Nrf1) also known as nuclear factor erythroid-2-like 1 (NFE2L1) is a protein that in humans is encoded by the NFE2L1 gene.

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Nutriepigenomics

Nutriepigenomics is the study of food nutrients and their effects on human health through epigenetic modifications.

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Permanent neonatal diabetes mellitus

A newly identified and potentially treatable form of monogenic diabetes is the neonatal diabetes caused by activating mutations of the KCNJ11 gene, which codes for the Kir6.2 subunit of the beta cell KATP channel.

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Propionyl-CoA carboxylase

Propionyl-CoA carboxylase catalyses the carboxylation reaction of propionyl CoA in the mitochondrial matrix.

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Tagatose

Tagatose is a sweetener based on its properties as a monosaccharide, specifically a hexose.

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Voltage-dependent anion channel

Voltage-dependent anion channels are a class of porin ion channel located on the outer mitochondrial membrane.

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1,5-Anhydroglucitol

Structure of 1,5-anhydroglucitol 1,5-Anhydroglucitol, also known as 1,5-AG, is a naturally occurring monosaccharide found in nearly all foods.

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Redirects here:

ATP:D-glucose 6-phosphotransferase, EC 2.7.1.2, GCK (gene), HHF3, Hhf3, MODY2, Mody2.

References

[1] https://en.wikipedia.org/wiki/Glucokinase

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