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142 relations: Acute generalized exanthematous pustulosis, Aeroallergen, AIDS Clinical Trials Group, AP-1 transcription factor, Arachidonate 5-lipoxygenase, AU-rich element, Basophilia, BCL2-related protein A1, Blastocystosis, Bone marrow suppression, C-Jun N-terminal kinases, Caladrius Biosciences, Cambridge Antibody Technology, Cancer immunotherapy, Cancer vaccine, CCL6, CD14, CFU-GM, CGTG-102, Chikungunya, Chronic myelogenous leukemia, Chronic myelomonocytic leukemia, Cochliobolus lunatus, Colony-stimulating factor, Crenolanib, Cytokine, Dendreon, Dendritic cell-based cancer vaccine, Dinutuximab, DNA vaccination, Donald Metcalf, Ecthyma gangrenosum, Embryo quality, Embryokine, Eosinophilic gastroenteritis, Epithelioid sarcoma, Familial eosinophilia, Fc receptor, Febrile neutrophilic dermatosis, Fibroblast growth factor, Filgotinib, Filgrastim, GATA2 deficiency, Gimsilumab, GPR132, GPR84, Granulocyte-macrophage colony-stimulating factor receptor, Growth factor, GVAX, Haematopoiesis, ..., Herpesviridae, HL60, Hypereosinophilia, Immunologic activation, Immunostimulant, IMP321, Index of biochemistry articles, Index of HIV/AIDS-related articles, Index of immunology articles, Index of oncology articles, Indium lung, Interleukin 10, Interleukin 15, Interleukin 17, Interleukin 19, Interleukin 27, Interleukin 3, Interleukin 5, Interleukin-5 receptor, Janus kinase 2, Janus kinase 3, Jennerex, Juvenile myelomonocytic leukemia, Kenneth Kaushansky, LECT2, LECT2 amyloidosis, Lenalidomide, Lenzilumab, Li Zaiping, List of medical abbreviations: G, List of MeSH codes (D08), List of MeSH codes (D12.644), List of MeSH codes (D12.776), List of MeSH codes (D12.776.395), List of MeSH codes (D12.776.543), List of MeSH codes (D23), List of therapeutic monoclonal antibodies, Ludwig Cancer Research, Lymphocyte-variant hypereosinophilia, Lymphokine, Macrophage activation syndrome, Macrophage polarization, Megakaryocyte, MicroRNA, Molgramostim, Monocyte, MorphoSys, Myeloid-derived suppressor cell, Namilumab, National Cancer Institute, Natural killer T cell, Neonatal sepsis, Neuroblastoma, Neurotrophic factors, Neutrophil-specific granule deficiency, NeuVax, Neuvenge, North China Pharmaceutical Group Corp, Oncolytic herpes virus, Oprelvekin, Outline of immunology, PDGFRB, Pexastimogene devacirepvec, Programmed cell death protein 1, Proinflammatory cytokine, PTPRC, Pulmonary alveolar proteinosis, Reticular dysgenesis, Sargramostim, Severe cutaneous adverse reactions, SIGLEC8, Sipuleucel-T, SOCS2, SOCS6, Steven Rosenberg, Suppressor of cytokine signaling 1, T helper 17 cell, Talimogene laherparepvec, Targeted molecular therapy for neuroblastoma, Third-hand smoke, Tolerogenic therapy, Transactivation, Transgene SA, Transplantable organs and tissues, Tumor antigen vaccine, Tumor microenvironment, U937 (cell line), Viralytics, Virus, VLDL receptor, 5-Hydroxyeicosatetraenoic acid, 5-oxo-eicosatetraenoic acid. Expand index (92 more) »
Acute generalized exanthematous pustulosis
Acute generalized exanthematous pustulosis (AGEP) (also known as pustular drug eruption and toxic pustuloderma) is a rare skin reaction that in 90% of cases is related to medication administration.
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Aeroallergen
An aeroallergen (pronounced aer·o·al·ler·gen) is any airborne substance, such as pollen or spores, which triggers an allergic reaction.
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AIDS Clinical Trials Group
The AIDS Clinical Trials Group network (ACTG) is one of the largest HIV clinical trials organizations in the world, playing a major role in setting standards of care for HIV infection and opportunistic diseases related to HIV and AIDS in the United States and the developing world.
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AP-1 transcription factor
Activator protein 1 (AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and bacterial and viral infections.
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Arachidonate 5-lipoxygenase
Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is a non-heme iron-containing enzyme (EC 1.13.11.34) that in humans is encoded by the ALOX5 gene.
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AU-rich element
Adenylate-uridylate-rich elements (AU-rich elements; AREs) are found in the 3' untranslated region (UTR) of many messenger RNAs (mRNAs) that code for proto-oncogenes, nuclear transcription factors, and cytokines.
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Basophilia
Basophilia is a condition derived from Basophils.
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BCL2-related protein A1
Bcl-2-related protein A1 is a protein that in humans is encoded by the BCL2A1 gene.
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Blastocystosis
Blastocystosis refers to a medical condition caused by infection with Blastocystis.
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Bone marrow suppression
Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes).
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C-Jun N-terminal kinases
c-Jun N-terminal kinases (JNKs), were originally identified as kinases that bind and phosphorylate c-Jun on Ser-63 and Ser-73 within its transcriptional activation domain.
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Caladrius Biosciences
Caladrius Biosciences is an American biopharmaceutical company active in the field of stem cell therapy and regenerative medicine, particularly (in 2012) of cardiovascular disease.
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Cambridge Antibody Technology
Cambridge Antibody Technology (officially Cambridge Antibody Technology Group Plc, informally CAT) was a biotechnology company headquartered in Cambridge, England, United Kingdom.
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Cancer immunotherapy
Cancer immunotherapy (sometimes called immuno-oncology, abbreviated IO) is the use of the immune system to treat cancer.
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Cancer vaccine
A cancer vaccine is a vaccine that either treats existing cancer or prevents development of a cancer.
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CCL6
Chemokine (C-C motif) ligand 6 (CCL6) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents.
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CD14
CD14 (cluster of differentiation 14) is a human gene.
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CFU-GM
CFU-GM (or "GMP", for "granulocyte-macrophage progenitor") is a colony forming unit.
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CGTG-102
CGTG-102 (Ad5/3-D24-GMCSF), (developed by Oncos Therapeutics) is an oncolytic adenovirus currently in orphan drug status for soft tissue sarcomas.
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Chikungunya
Chikungunya is an infection caused by the chikungunya virus (CHIKV).
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Chronic myelogenous leukemia
Chronic myelogenous leukemia (CML), also known as chronic myeloid leukemia, is a cancer of the white blood cells.
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Chronic myelomonocytic leukemia
Chronic myelomonocytic leukaemia (CMML) is a type of leukaemia, which are cancers of the blood-forming cells of the bone marrow.
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Cochliobolus lunatus
Cochliobolus lunatus is a fungal plant pathogen that can cause disease in humans and other animals.
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Colony-stimulating factor
Colony-stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of hemopoietic stem cells, thereby activating intracellular signaling pathways that can cause the cells to proliferate and differentiate into a specific kind of blood cell (usually white blood cells. For red blood cell formation, see erythropoietin).
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Crenolanib
Crenolanib besylate (CP-868,596-26 or AR-868,596-26, 4-piperidinamine, 1--, monobenzenesulfonate) is an investigational inhibitor being developed by AROG Pharmaceuticals, LLC.
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Cytokine
Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.
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Dendreon
Dendreon is a biotechnology company.
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Dendritic cell-based cancer vaccine
Dendritic cells (DCs) are most powerful antigen presenting cells for the induction of antigen specific T cell response and because of this function DCs are the crucial component of vaccination.
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Dinutuximab
Dinutuximab (Ch14.18, tradename Unituxin) and Dinutuximab beta (tradename Isquette) is a monoclonal antibody used as a second-line treatment for children with high-risk neuroblastoma.
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DNA vaccination
DNA vaccination is a technique for protecting against disease by injection with genetically engineered DNA so cells directly produce an antigen, producing a protective immunological response.
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Donald Metcalf
Donald Metcalf AC FRS FAA (26 February 1929 – 15 December 2014) was an Australian medical researcher who spent most of his career at the Walter and Eliza Hall Institute of Medical Research in Melbourne.
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Ecthyma gangrenosum
Ecthyma gangrenosum is a type of skin lesion characterized by vesicles or blisters which rapidly evolve into pustules and necrotic ulcers with undermined tender erythematous border.
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Embryo quality
Embryo quality is the ability of an embryo to perform successfully in terms of conferring a high pregnancy rate and/or resulting in a healthy person.
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Embryokine
Embryokines (Greek: embryuon "embryo" + kinōs "movement") are regulatory molecules produced by the reproductive tract that modulate embryonic development.
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Eosinophilic gastroenteritis
Eosinophilic gastroenteritis (EG) is a rare and heterogeneous condition characterized by patchy or diffuse eosinophilic infiltration of gastrointestinal (GI) tissue, first described by Kaijser in 1937.
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Epithelioid sarcoma
Epithelioid sarcoma is a rare soft tissue sarcoma arising from mesenchymal tissue and characterized by epithelioid-like features.
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Familial eosinophilia
Familial eosinophilia is a rare congenital disorder characterized by the presence of sustained elevations in blood eosinophil levels that reach ranges diagnostic of eosinophilia (i.e. 500-1500/microliter) or, far more commonly,hypereosinophilia (i.e. >1,500/microliter).
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Fc receptor
An Fc receptor is a protein found on the surface of certain cells – including, among others, B lymphocytes, follicular dendritic cells, natural killer cells, macrophages, neutrophils, eosinophils, basophils, human platelets, and mast cells – that contribute to the protective functions of the immune system.
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Febrile neutrophilic dermatosis
Sweet's syndrome (SS), or acute febrile neutrophilic dermatosis is a skin disease characterized by the sudden onset of fever, an elevated white blood cell count, and tender, red, well-demarcated papules and plaques that show dense infiltrates by neutrophil granulocytes on histologic examination.
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Fibroblast growth factor
The fibroblast growth factors are a family of cell signalling proteins that are involved in a wide variety of processes, most notably as crucial elements for normal development.
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Filgotinib
Filgotinib (code name GLPG0634) is a drug which is currently under investigation for the treatment of rheumatoid arthritis (RA) and Crohn's disease.
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Filgrastim
Filgrastim, sold under the brand name Neupogen among others, is a medication used to treat low blood neutrophils.
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GATA2 deficiency
GATA2 deficiency (also termed GATA2 haploinsufficiency or GATA2 deficiency syndrome) is a recently defined grouping of several disorders caused by common defect, viz., familial or sporadic inactivating mutations in one of the two parental GATA2 genes.
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Gimsilumab
Gimsilumab (MORAb-022) (INN) is a human monoclonal antibody designed for the treatment of rheumatoid arthritis.
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GPR132
G protein coupled receptor 132, also termed G2A, is classified as a member of the proton sensing G protein coupled receptor (GPR) subfamily.
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GPR84
Probable G-protein coupled receptor 84 is a protein that in humans is encoded by the GPR84 gene.
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Granulocyte-macrophage colony-stimulating factor receptor
The granulocyte-macrophage colony-stimulating factor receptor also known as CD116 (Cluster of Differentiation 116), is a receptor for granulocyte-macrophage colony-stimulating factor, which stimulates the production of white blood cells.
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Growth factor
A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.
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GVAX
GVAX is a cancer vaccine composed of whole tumor cells genetically modified to secrete the immune stimulatory cytokine, granulocyte-macrophage colony-stimulating factor (GM-CSF), and then irradiated to prevent further cell division.
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Haematopoiesis
Haematopoiesis (from Greek αἷμα, "blood" and ποιεῖν "to make"; also hematopoiesis in American English; sometimes also haemopoiesis or hemopoiesis) is the formation of blood cellular components.
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Herpesviridae
Herpesviridae is a large family of DNA viruses that cause diseases in animals, including humans.
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HL60
The HL-60 cell line is a human leukemia cell line that has been used for laboratory research on blood cell formation and physiology.
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Hypereosinophilia
Hypereosinophilia is an elevation in an individual's circulating blood eosinophil count above 15.0 x 109/L (i.e. 1,500/μL).
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Immunologic activation
In immunology, activation is the transition of leucocytes and other cell types involved in the immune system.
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Immunostimulant
Immunostimulants, also known as immunostimulators, are substances (drugs and nutrients) that stimulate the immune system by inducing activation or increasing activity of any of its components.
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IMP321
IMP321 is a large molecule cancer drug being developed by the clinical stage biotechnology company Prima BioMed (Nasdaq: IMMP).
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Index of biochemistry articles
Biochemistry is the study of the chemical processes in living organisms.
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Index of HIV/AIDS-related articles
This is a list of AIDS-related topics, many of which were originally taken from the public domain U.S. Department of Health Glossary of HIV/AIDS-Related Terms, 4th Edition.
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Index of immunology articles
Immunology is the study of the immune system during health and disease.
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Index of oncology articles
This is a list of terms related to oncology.
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Indium lung
Indium lung is a rare occupational lung disease caused by exposure to respirable indium in the form of indium tin oxide.
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Interleukin 10
Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine.
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Interleukin 15
Interleukin-15 (IL-15) is a cytokine with structural similarity to Interleukin-2 (IL-2).
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Interleukin 17
Interleukin 17A (IL-17 or IL-17A) is a pro-inflammatory cytokine.
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Interleukin 19
Interleukin 19 (IL19) is a protein that in humans is encoded by the IL19 gene.
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Interleukin 27
Interleukin 27 (IL-27) is a member of the IL-12 cytokine family.
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Interleukin 3
Interleukin 3 (IL-3) is a protein that in humans is encoded by the IL3 gene.
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Interleukin 5
Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells.
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Interleukin-5 receptor
The interleukin-5 receptor is a type I cytokine receptor.
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Janus kinase 2
Janus kinase 2 (commonly called JAK2) is a non-receptor tyrosine kinase.
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Janus kinase 3
Tyrosine-protein kinase JAK3 is an enzyme that in humans is encoded by the JAK3 gene.
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Jennerex
Jennerex Biotherapeutics, Inc. (now owned by the Korean firm SillaJen) was an American private biopharmaceutical company that developed the oncolytic viruses JX-594 and JX-929 among others.
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Juvenile myelomonocytic leukemia
Juvenile myelomonocytic leukemia (JMML) is a serious chronic leukemia (cancer of the blood) that affects children mostly aged 4 and younger.
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Kenneth Kaushansky
Kenneth Kaushansky, M.D., Master of the American College of Physicians (MACP) (born October 20, 1953) is an American medical doctor, hematologist, former editor of the medical journal Blood, and has served as the Dean of the Stony Brook University School of Medicine since July 2010.
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LECT2
Leukocyte cell-derived chemotaxin-2 (LECT2) is a protein first described in 1996 as a chemotactic factor for neutrophils, i.e. it stimulated human neutrophils to move directionally in an in vitro assay system.
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LECT2 amyloidosis
LECT2 Amyloidosis (ALECT2) is a form of amyloidosis caused by the LECT2 protein.
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Lenalidomide
Lenalidomide (trade name Revlimid) is a derivative of thalidomide introduced in 2004.
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Lenzilumab
Lenzilumab (INN) (alternative identifier KB003) is a humanized monoclonal antibody (class IgG1 kappa) that targets colony stimulating factor 2 (CSF2)/granulocyte-macrophage colony stimulating factor (GM-CSF) designed for the treatment of chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML).
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Li Zaiping
Li Zaiping (17 August 1925 – 30 May 2018) was a Chinese molecular biologist considered a pioneer in genetic science and engineering in China.
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List of medical abbreviations: G
Category:Lists of medical abbreviations.
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List of MeSH codes (D08)
This is the fourth part of the list of the "D" codes for MeSH.
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List of MeSH codes (D12.644)
This is part of the list of the "D" codes for MeSH.
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List of MeSH codes (D12.776)
This is part of the list of the "D" codes for MeSH.
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List of MeSH codes (D12.776.395)
This is a sub-part (glycoproteins only) of List of MeSH codes (D12.776), itself a part of the list of the "D" codes for MeSH.
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List of MeSH codes (D12.776.543)
This is a sub-part (membrane proteins only) of List of MeSH codes (D12.776), itself a part of the list of the "D" codes for MeSH.
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List of MeSH codes (D23)
This is the fourth part of the list of the "D" codes for MeSH.
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List of therapeutic monoclonal antibodies
This is a list of therapeutic, diagnostic and preventive monoclonal antibodies, antibodies that are clones of a single parent cell.
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Ludwig Cancer Research
Ludwig Cancer Research is an international community of scientists focused on cancer research, with the goals of preventing and controlling cancer.
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Lymphocyte-variant hypereosinophilia
Lymphocyte-variant hypereosinophila, also termed lymphocyte variant eosinophilia, is a rare disorder in which eosinophilia or hypereosinophilia (i.e. a large or extremely large increase in the number of eosinophils in the blood circulation) is caused by an aberrant population of lymphocytes.
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Lymphokine
Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte.
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Macrophage activation syndrome
Macrophage-activation syndrome (MAS) is a severe, potentially life-threatening, complication of several chronic rheumatic diseases of childhood.
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Macrophage polarization
Macrophage polarization is a process by which macrophage expresses different functional programs in response to microenvironmental signals.
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Megakaryocyte
A megakaryocyte (mega- + karyo- + -cyte, "large-nucleus cell") is a large bone marrow cell with a lobated nucleus responsible for the production of blood thrombocytes (platelets), which are necessary for normal blood clotting.
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MicroRNA
A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression.
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Molgramostim
Molgramostim is a recombinant granulocyte macrophage colony-stimulating factor which functions as an immunostimulator.
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Monocyte
Monocytes are a type of leukocyte, or white blood cell.
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MorphoSys
MorphoSys AG is a German biotechnology company.
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Myeloid-derived suppressor cell
MDSC (myeloid-derived suppressor cells) are a heterogenous group of immune cells from the myeloid lineage (a family of cells that originate from bone marrow stem cells).
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Namilumab
Namilumab (alternative identifier MT203) is a human monoclonal antibody (class IgG1 kappa) that targets granulocyte macrophage-colon stimulating factor (GM-CSF)/colony stimulating factor 2 (CSF2) and is currently being researched for application in rheumatoid arthritis (RA) and psoriatic arthritis.
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National Cancer Institute
The National Cancer Institute (NCI) is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services.
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Natural killer T cell
Natural killer T (NKT) cells are a heterogeneous group of T cells that share properties of both T cells and natural killer cells.
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Neonatal sepsis
Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) (such as meningitis, pneumonia, pyelonephritis, or gastroenteritis) in the setting of fever.
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Neuroblastoma
Neuroblastoma (NB) is a type of cancer that forms in certain types of nerve tissue. It most frequently starts from one of the adrenal glands, but can also develop in the neck, chest, abdomen, or spine. Symptoms may include bone pain, a lump in the abdomen, neck, or chest, or a painless bluish lump under the skin. Occasionally, neuroblastoma may be due to a mutation inherited from a person's parents. Environmental factors have not been found to be involved. Diagnosis is based on a tissue biopsy. Occasionally it may be found in a baby by ultrasound during pregnancy. At diagnosis, the cancer has usually already spread. The cancer is divided into low-, intermediate-, and high-risk groups based on a child's age, cancer stage, and what the cancer looks like. Treatment and outcomes depends on the risk group a person is in. Treatments may include observation, surgery, radiation, chemotherapy, or stem cell transplantation. Low-risk disease in babies typically has a good outcome with surgery or simply observation. In high-risk disease, chances of long-term survival, however, are less than 40% despite aggressive treatment. Neuroblastoma is the most common cancer in babies and the third-most common cancer in children after leukemia and brain cancer. About one in every 7,000 children is affected at some time. About 90% of cases occur in children less than 5 years old and it is rare in adults. Of cancer deaths in children, about 15% are due to neuroblastoma. The disease was first described in the 1800s.
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Neurotrophic factors
Neurotrophic factors (NTFs) are a family of biomolecules – nearly all of which are peptides or small proteins – that support the growth, survival, and differentiation of both developing and mature neurons.
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Neutrophil-specific granule deficiency
Neutrophil-specific granule deficiency (SGD, previously known as lactoferrin deficiency) is a rare congenital immunodeficiency characterized by an increased risk for pyogenic infections due to defective production of specific granules and gelatinase granules in patient neutrophils.
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NeuVax
NeuVax is a peptide vaccine aimed at preventing or delaying the recurrence of breast cancer in cancer survivors who achieve remission after standard of care treatment (e.g., surgery, radiation, chemotherapy).
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Neuvenge
Neuvenge, Lapuleucel-T (APC 8024), is a therapeutic cancer vaccine (TCV) in development (clinical trial) by Dendreon (DNDN).
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North China Pharmaceutical Group Corp
North China Pharmaceutical Group Corp. (NCPC), is a leading pharmaceutical manufacturer in China.
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Oncolytic herpes virus
Many variants of herpes simplex virus have been considered for viral therapy of cancer; the early development of these was thoroughly reviewed in the journal Cancer Gene Therapy in 2002.
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Oprelvekin
Oprelvekin is recombinant interleukin eleven (IL-11), a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
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Outline of immunology
The following outline is provided as an overview of and topical guide to immunology: Immunology is the study of all aspects of the immune system in all organisms.
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PDGFRB
Beta-type platelet-derived growth factor receptor is a protein that in humans is encoded by the PDGFRB gene.
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Pexastimogene devacirepvec
JX-594 is an oncolytic virus (also known as Pexa-Vec, INN pexastimogene devacirepvec) originally constructed in Dr.
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Programmed cell death protein 1
Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279), is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.
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Proinflammatory cytokine
A proinflammatory cytokine or more simply an inflammatory cytokine is a type of signaling molecule (a cytokine) that is excreted from immune cells like helper T cells (Th) and macrophages, and certain other cell types that promote inflammation.
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PTPRC
Protein tyrosine phosphatase, receptor type, C also known as PTPRC is an enzyme that, in humans, is encoded by the PTPRC gene.
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Pulmonary alveolar proteinosis
Pulmonary alveolar proteinosis (PAP) is a group of rare lung disorders characterized by abnormal accumulation of surfactant-derived lipoprotein compounds within the alveoli of the lung.
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Reticular dysgenesis
Reticular dysgenesis (RD) is a rare, inherited autosomal recessive disease that results in immunodeficiency.
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Sargramostim
Sargramostim (tradename Leukine) is a recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) that functions as an immunostimulator.
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Severe cutaneous adverse reactions
Severe cutaneous adverse reactions or SCARs are a group of potentially lethal adverse drug reactions that involve the skin and mucous membranes of various body openings such as the eyes, ears, and inside the nose, mouth, and lips.
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SIGLEC8
Sialic acid-binding Ig-like lectin 8 is a protein that in humans is encoded by the SIGLEC8 gene.
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Sipuleucel-T
Sipuleucel-T (APC8015, trade name Provenge), developed by Dendreon Corporation, is a cell-based cancer immunotherapy for prostate cancer (CaP).
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SOCS2
Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene.
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SOCS6
Suppressor of cytokine signaling 6 is a protein that in humans is encoded by the SOCS6 gene.
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Steven Rosenberg
Steven A. Rosenberg (born 2 August 1940) is an American cancer researcher and surgeon, chief of Surgery at the National Cancer Institute in Bethesda, Maryland and a Professor of Surgery at the Uniformed Services University of Health Sciences and the George Washington University School of Medicine and Health Sciences.
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Suppressor of cytokine signaling 1
Suppressor of cytokine signaling 1 is a protein that in humans is encoded by the SOCS1 gene.
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T helper 17 cell
T helper 17 cells (Th17) are a subset of pro-inflammatory T helper cells defined by their production of interleukin 17 (IL-17).
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Talimogene laherparepvec
Talimogene laherparepvec is a biopharmaceutical drug to treat melanoma lesions that cannot be operated on; it is injected directly into the lesion.
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Targeted molecular therapy for neuroblastoma
Targeted molecular therapy for neuroblastoma involves treatment aimed at molecular targets that have a unique expression in this form of cancer.
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Third-hand smoke
Third-hand smoke is contamination by tobacco smoke that lingers following the extinguishing of a cigarette, cigar, or other combustible tobacco product.
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Tolerogenic therapy
Tolerogenic therapy aims to induce immune tolerance where there is pathological or undesirable activation of the normal immune response.
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Transactivation
In the context of gene regulation: transactivation is the increased rate of gene expression triggered either by biological processes or by artificial means, through the expression of an intermediate transactivator protein.
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Transgene SA
Transgene SA is a France-based fully integrated biopharmaceutical company specialising in immunotherapeutics to treat cancer and infectious diseases.
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Transplantable organs and tissues
Transplantable organs and tissues may both refer to organs and tissues that are relatively often or routinely transplanted (here "main organs and tissues"), as well as relatively seldom transplanted organs and tissues and ones on the experimental stage.
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Tumor antigen vaccine
According to the National Cancer Institute, a tumor antigen vaccine is a "vaccine made of cancer cells, parts of cancer cells, or pure tumor antigens (substances isolated from tumor cells)".
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Tumor microenvironment
The tumor microenvironment (TME) is the cellular environment in which the tumor exists, including surrounding blood vessels, immune cells, fibroblasts, bone marrow-derived inflammatory cells, lymphocytes, signaling molecules and the extracellular matrix (ECM).
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U937 (cell line)
U937 cells are a model cell line used in biomedical research.
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Viralytics
Viralytics Ltd is an Australian biotechnology company working in the field of oncolytic viruses, that is, viruses that preferentially infect and kill cancer cells. The company's oncolytic virus product, called Cavatak, is currently in clinical trials in metastatic melanoma and other cancers. The drug was granted Orphan Drug status in advanced melanoma in December 2005. In February 2018, Merck & Co. announced it would acquire Viralytics for AUD$502 million ($394 million).
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Virus
A virus is a small infectious agent that replicates only inside the living cells of other organisms.
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VLDL receptor
The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor of the low-density-lipoprotein (LDL) receptor family.
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5-Hydroxyeicosatetraenoic acid
5-Hydroxyeicosatetraenoic acid (5-HETE, 5(S)-HETE, or 5S-HETE) is an eicosanoid, i.e. a metabolite of arachidonic acid.
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5-oxo-eicosatetraenoic acid
5-Oxo-eicosatetraenoic acid (i.e. 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid; also termed 5-oxo-ETE and 5-oxoETE) is a Nonclassic eicosanoid metabolite of arachidonic acid and the most potent naturally occurring member of the 5-HETE family of cell signaling agents.
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Redirects here:
CSF2, CSF2 (gene), Colony stimulating factor 2, GM-CSF, GMCSF, Gmcsf, Granulocyte Macrophage-colony stimulating factor, Granulocyte macrophage colony stimulating factor, Granulocyte macrophage colony-stimulating factor, Granulocyte macrophage colony-stimulating factors, Granulocyte macrophage colony-stimulating factors, recombinant, Granulocyte macrophage-colony stimulating factor, Granulocyte-Macrophage Colony Stimulating Factor, Granulocyte-Monocyte - Colony Stimulating Factor, Granulocyte-macrophage CSF, Granulocyte-macrophage colony stimulating factor, Receptor, macrophage colony-stimulating factor, Receptors, granulocyte-macrophage colony-stimulating factor, RhGM-CSF.
References
[1] https://en.wikipedia.org/wiki/Granulocyte-macrophage_colony-stimulating_factor
