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ICAM-1

Index ICAM-1

ICAM-1 (Intercellular Adhesion Molecule 1) also known as CD54 (Cluster of Differentiation 54) is a protein that in humans is encoded by the ICAM1 gene. [1]

99 relations: Addressin, Alicaforsen, Aorta-gonad-mesonephros, Artificial antigen presenting cells, Basophil, CD154, CD36, Common cold, Cytotrienin A, Development of analogs of thalidomide, Diosmin, E-selectin, EGFL7, Epoxyeicosatrienoic acid, Ezrin, Foam cell, Gamma delta T cell, Golimumab, High endothelial venules, IgSF CAM, ImKTx88, Immunoglobulin superfamily, Immunological constant of rejection, Immunological synapse, Inflammation, Inflammatory bowel disease, Integrin, Integrin alpha L, Integrin beta 2, Intercellular adhesion molecule, Interleukin, Interleukin 26, Interleukin 8, IRF8, Keratoconus, Kohzoh Imai, Leukocyte adhesion deficiency, Leukocyte extravasation, Lifitegrast, List of human clusters of differentiation, List of therapeutic monoclonal antibodies, Lymphocyte function-associated antigen 1, Melanocyte, Mifamurtide, Outline of immunology, Park Seong-hoe, Plasmodium falciparum erythrocyte membrane protein 1, Poly (ADP-ribose) polymerase, PRKCQ, Prostvac, ..., Proteasome, Proteasome (prosome, macropain) subunit, alpha 1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB10, PSMB2, PSMB3, PSMB4, PSMB5, PSMB6, PSMB7, PSMB8, PSMB9, PSMC1, PSMD1, PSMD10, PSMD11, PSMD12, PSMD13, PSMD14, PSMD2, PSMD3, PSMD4, PSMD5, PSMD6, PSMD7, PSMD8, PSMD9, Resistin, Rhinovirus, Selective glucocorticoid receptor modulator, SGEF, Soluble cell adhesion molecules, Spermatogenesis, Targeted drug delivery, Thromboxane receptor, Thymic nurse cell, TIE1, Ulcerative colitis, Uropod (immunology), Viral synapse, Viralytics, Xenotransplantation, Zicam. Expand index (49 more) »

Addressin

Addressin also known as mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) is a protein that in humans is encoded by the MADCAM1 gene.

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Alicaforsen

Alicaforsen is an antisense oligonucleotide therapeutic that targets the messenger RNA for the production of human ICAM-1 protein.

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Aorta-gonad-mesonephros

The aorta-gonad-mesonephros (AGM) is a region of embryonic mesoderm that develops during embryonic development from the para-aortic splanchnopleura in chick, mouse and human embryos.

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Artificial antigen presenting cells

Artificial antigen presenting cells (aAPCs) are a new technology and approach to cancer immunotherapy.

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Basophil

Basophils are a type of white blood cells.

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CD154

CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules.

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CD36

CD36 (cluster of differentiation 36), also known as platelet glycoprotein 4, fatty acid translocase (FAT), scavenger receptor class B member 3 (SCARB3), and glycoproteins 88 (GP88), IIIb (GPIIIB), or IV (GPIV) is a protein that in humans is encoded by the CD36 gene.

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Common cold

The common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory tract that primarily affects the nose.

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Cytotrienin A

Cytotrienin A (Cyt A) is a secondary metabolite isolated from Streptomyces sp. RK95-74 isolated from soil in Japan in 1997.

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Development of analogs of thalidomide

The development of analogs of thalidomide was precipitated by the discovery of the anti-angiogenic and anti-inflammatory properties of the drug yielding a new way of fighting cancer as well as some inflammatory diseases after it had been banned in 1961.

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Diosmin

Diosmin (diosmetin 7-O-rutinoside), a flavone derivative also known as venosmine, is a glycoside of diosmetin, which in turn is the 4'-methoxy derivative of luteolin.

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E-selectin

E-selectin, also known as CD62 antigen-like family member E (CD62E), endothelial-leukocyte adhesion molecule 1 (ELAM-1), or leukocyte-endothelial cell adhesion molecule 2 (LECAM2), is a cell adhesion molecule expressed only on endothelial cells activated by cytokines.

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EGFL7

EGF-like domain-containing protein 7 is a protein that in humans is encoded by the EGFL7 gene.

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Epoxyeicosatrienoic acid

The epoxyeicosatrienoic acids or EETs are signaling molecules formed within various types of cells by the metabolism of arachidonic acid by a specific subset of Cytochrome P450 enzymes termed cytochrome P450 epoxygenases.

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Ezrin

Ezrin also known as cytovillin or villin-2 is a protein that in humans is encoded by the EZR gene.

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Foam cell

Foam cells are the fat-laden M2 macrophages that serve as the hallmark of early stage atherosclerotic lesion formation.

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Gamma delta T cell

Gamma delta T cells (γδ T cells) are T cells that have a distinctive T-cell receptor (TCR) on their surface.

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Golimumab

Golimumab (CNTO 148) is a human monoclonal antibody which is used as an immunosuppressive drug and marketed under the brand name Simponi.

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High endothelial venules

High endothelial venules (HEV) are specialized post-capillary venous swellings characterized by plump endothelial cells as opposed to the usual thinner endothelial cells found in regular venules.

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IgSF CAM

Immunoglobulin superfamily CAMs (IgSF CAMs) are a class of cell adhesion molecules.

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ImKTx88

ImKTx88 is a selective inhibitor of the Kv1 ion channel family that can be isolated from the venom of the Isometrus maculatus (lesser brown scorpion).

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Immunoglobulin superfamily

The immunoglobulin superfamily (IgSF) is a large protein superfamily of cell surface and soluble proteins that are involved in the recognition, binding, or adhesion processes of cells.

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Immunological constant of rejection

The Immunologic Constant of Rejection (ICR), is a set of genes that is involved in tissue destruction along a diverse set of physiological circumstances like autoimmune disease or allograft rejection or pathological conditions like infection and cancer.

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Immunological synapse

In immunology, an immunological synapse (or immune synapse) is the interface between an antigen-presenting cell or target cell and a lymphocyte such as an effector T cell or Natural Killer cell.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Inflammatory bowel disease

Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.

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Integrin

Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion.

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Integrin alpha L

Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a human gene which functions in the immune system.

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Integrin beta 2

In molecular biology, CD18 (Integrin beta chain-2) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans.

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Intercellular adhesion molecule

In molecular biology, intercellular adhesion molecules (ICAMs) and vascular cell adhesion molecule-1 (VCAM-1) are part of the immunoglobulin superfamily.

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Interleukin

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that were first seen to be expressed by white blood cells (leukocytes).

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Interleukin 26

Interleukin-26 (IL-26) is a protein that in humans is encoded by the IL26 gene.

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Interleukin 8

Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells.

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IRF8

Interferon regulatory factor 8 (IRF8) also known as interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the IRF8 gene.

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Keratoconus

Keratoconus (KC) is a disorder of the eye which results in progressive thinning of the cornea.

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Kohzoh Imai

Kohzoh Imai (今井浩三, Kohzoh Imai, born January 1, 1948) is a Japanese physician and oncologist specializing in molecular diagnosis and novel medical treatment of cancer.

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Leukocyte adhesion deficiency

Leukocyte adhesion deficiency (LAD), is a rare autosomal recessive disorder characterized by immunodeficiency resulting in recurrent infections.

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Leukocyte extravasation

Leukocyte extravasation, less commonly called diapedesis, is the movement of leukocytes out of the circulatory system and towards the site of tissue damage or infection.

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Lifitegrast

Lifitegrast (trade name Xiidra) is an FDA approved drug indicated for the treatment of signs and symptoms of dry eye, a syndrome called keratoconjunctivitis sicca.

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List of human clusters of differentiation

The following is a list of human clusters of differentiation (or CD) molecules.

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List of therapeutic monoclonal antibodies

This is a list of therapeutic, diagnostic and preventive monoclonal antibodies, antibodies that are clones of a single parent cell.

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Lymphocyte function-associated antigen 1

Lymphocyte function-associated antigen 1 (LFA-1) is a cellular adhesion molecule found on lymphocytes.

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Melanocyte

Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), the inner ear, vaginal epithelium, meninges, bones, and heart.

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Mifamurtide

Mifamurtide (trade name Mepact, marketed by Takeda) is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults, which is lethal in about a third of cases.

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Outline of immunology

The following outline is provided as an overview of and topical guide to immunology: Immunology is the study of all aspects of the immune system in all organisms.

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Park Seong-hoe

Seong Hoe Park (born October 3, 1947) is a Korean immunologist and pathologist and a distinguished professor of pathology at the Seoul National University College of Medicine.

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Plasmodium falciparum erythrocyte membrane protein 1

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a family of proteins present on the membrane surface of red blood cells (RBCs or erythrocytes) that are infected by the malarial parasite Plasmodium falciparum.

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Poly (ADP-ribose) polymerase

Poly (ADP-ribose) polymerase (PARP) is a family of proteins involved in a number of cellular processes such as DNA repair, genomic stability, and programmed cell death.

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PRKCQ

Protein kinase C theta (PKC-θ) is an enzyme that in humans is encoded by the PRKCQ gene.

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Prostvac

PROSTVAC (rilimogene galvacirepvec/rilimogene glafolivec) is a cancer immunotherapy candidate in clinical development by Bavarian Nordic for the treatment of all prostate cancer although clinical trials are focusing on more advanced cases of metastatic castration-resistant prostate cancer (mCRPC).

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Proteasome

Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.

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Proteasome (prosome, macropain) subunit, alpha 1

Proteasome subunit alpha type-1 is a protein that in humans is encoded by the PSMA1 gene.

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PSMA2

Proteasome subunit alpha type-2 is a protein that in humans is encoded by the PSMA2 gene.

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PSMA3

Proteasome subunit alpha type-3 also known as macropain subunit C8 and proteasome component C8 is a protein that in humans is encoded by the PSMA3 gene.

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PSMA4

Proteasome subunit alpha type-4 also known as macropain subunit C9, proteasome component C9, and 20S proteasome subunit alpha-3 is a protein that in humans is encoded by the PSMA4 gene.

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PSMA5

Proteasome subunit alpha type-5 also known as 20S proteasome subunit alpha-5 is a protein that in humans is encoded by the PSMA5 gene.

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PSMA6

Proteasome subunit alpha type-6 is a protein that in humans is encoded by the PSMA6 gene.

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PSMA7

Proteasome subunit alpha type-7 also known as 20S proteasome subunit alpha-4 is a protein that in humans is encoded by the PSMA7 gene.

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PSMB1

Proteasome subunit beta type-1 also known as 20S proteasome subunit beta-6 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB1 gene.

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PSMB10

Proteasome subunit beta type-10 as known as 20S proteasome subunit beta-2i is a protein that in humans is encoded by the PSMB10 gene.

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PSMB2

Proteasome subunit beta type-2 also known as 20S proteasome subunit beta-4 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB2 gene.

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PSMB3

Proteasome subunit beta type-3, also known as 20S proteasome subunit beta-3, is a protein that in humans is encoded by the PSMB3 gene.

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PSMB4

Proteasome subunit beta type-4 also known as 20S proteasome subunit beta-7 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB4 gene.

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PSMB5

Proteasome subunit beta type-5 as known as 20S proteasome subunit beta-5 is a protein that in humans is encoded by the PSMB5 gene.

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PSMB6

Proteasome subunit beta type-6 also known as 20S proteasome subunit beta-1 (based on systematic nomenclature) is a protein that in humans is encoded by the PSMB6 gene.

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PSMB7

Proteasome subunit beta type-7 as known as 20S proteasome subunit beta-2 is a protein that in humans is encoded by the PSMB7 gene.

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PSMB8

Proteasome subunit beta type-8 as known as 20S proteasome subunit beta-5i is a protein that in humans is encoded by the PSMB8 gene.

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PSMB9

Proteasome subunit beta type-9 as known as 20S proteasome subunit beta-1i is a protein that in humans is encoded by the PSMB9 gene.

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PSMC1

26S protease regulatory subunit 4, also known as 26S proteasome AAA-ATPase subunit Rpt2, is an enzyme that in humans is encoded by the PSMC1 gene.

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PSMD1

26S proteasome non-ATPase regulatory subunit 1, also as known as 26S Proteasome Regulatory Subunit Rpn2 (systematic nomenclature), is a protein that in humans is encoded by the PSMD1 gene.

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PSMD10

26S proteasome non-ATPase regulatory subunit 10 or gankyrin is an enzyme that in humans is encoded by the PSMD10 gene.

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PSMD11

26S proteasome non-ATPase regulatory subunit 11 is an enzyme that in humans is encoded by the PSMD11 gene.

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PSMD12

26S proteasome non-ATPase regulatory subunit 12 is an enzyme that in humans is encoded by the PSMD12 gene.

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PSMD13

26S proteasome non-ATPase regulatory subunit 13 is an enzyme that in humans is encoded by the PSMD13 gene.

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PSMD14

26S proteasome non-ATPase regulatory subunit 14, also known as 26S proteasome non-ATPase subunit Rpn11, is an enzyme that in humans is encoded by the PSMD14 gene.

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PSMD2

26S proteasome non-ATPase regulatory subunit 2, also as known as 26S Proteasome Regulatory Subunit Rpn1 (systematic nomenclature), is an enzyme that in humans is encoded by the PSMD2 gene.

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PSMD3

26S proteasome non-ATPase regulatory subunit 3 is an enzyme that in humans is encoded by the PSMD3 gene.

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PSMD4

26S proteasome non-ATPase regulatory subunit 4, also as known as 26S Proteasome Regulatory Subunit Rpn10 (systematic nomenclature), is an enzyme that in humans is encoded by the PSMD4 gene.

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PSMD5

26S proteasome non-ATPase regulatory subunit 5 is an enzyme that in humans is encoded by the PSMD5 gene.

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PSMD6

26S proteasome non-ATPase regulatory subunit 6 is an enzyme that in humans is encoded by the PSMD6 gene.

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PSMD7

26S proteasome non-ATPase regulatory subunit 7, also known as 26S proteasome non-ATPase subunit Rpn8, is an enzyme that in humans is encoded by the PSMD7 gene.

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PSMD8

26S proteasome non-ATPase regulatory subunit 8 is an enzyme that in humans is encoded by the PSMD8 gene.

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PSMD9

26S proteasome non-ATPase regulatory subunit 9 is an enzyme that in humans is encoded by the PSMD9 gene.

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Resistin

Resistin also known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) is a cysteine-rich adipose-derived peptide hormone that in humans is encoded by the RETN gene.

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Rhinovirus

The rhinovirus (from the Greek ῥίς rhis "nose", ῥινός rhinos "of the nose", and the Latin vīrus) is the most common viral infectious agent in humans and is the predominant cause of the common cold.

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Selective glucocorticoid receptor modulator

Selective glucocorticoid receptor modulators (SEGRMs) and selective glucocorticoid receptor agonists (SEGRAs) formerly known as dissociated glucocorticoid receptor agonists (DIGRAs) are a class of experimental drugs designed to share many of the desirable anti-inflammatory, immunosuppressive, or anticancer properties of classical glucocorticoid drugs but with fewer side effects such as skin atrophy.

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SGEF

SGEF (Src homology 3 domain-containing Guanine nucleotide Exchange Factor) is a 97 kDa protein involved in intracellular signalling networks. It functions as a guanine nucleotide exchange factor (GEF) for RhoG, a small G protein of the Rho family.

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Soluble cell adhesion molecules

Soluble cell adhesion molecules (sCAMs) are a class of cell adhesion molecule (CAMs - cell surface binding proteins) that may represent important biomarkers for inflammatory processes involving activation or damage to cells such as platelets and the endothelium.

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Spermatogenesis

Spermatogenesis is the process by which haploid spermatozoa develop from germ cells in the seminiferous tubules of the testis.

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Targeted drug delivery

Targeted drug delivery, sometimes called smart drug delivery, is a method of delivering medication to a patient in a manner that increases the concentration of the medication in some parts of the body relative to others.

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Thromboxane receptor

The thromboxane receptor (TP) also known as the prostanoid TP receptor is a protein that in humans is encoded by the TBXA2R gene, The thromboxane receptor is one among the five classes of prostanoid receptors and was the first eicosanoid receptor cloned.

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Thymic nurse cell

Thymic nurse cells (TNCs) are large epithelial cells found in the cortex of thymus and also in cortico-medullary junction.

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TIE1

Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 also known as TIE1 is an angiopoietin receptor which in humans is encoded by the TIE1 gene.

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Ulcerative colitis

Ulcerative colitis (UC) is a long-term condition that results in inflammation and ulcers of the colon and rectum.

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Uropod (immunology)

Uropods, in immunology, refer to the hind part of polarized cells during cell migration that stabilize and move the cell.

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Viral synapse

Viral synapse (or virological synapse) is a molecularly organized cellular junction that is similar in some aspects to immunological synapses.

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Viralytics

Viralytics Ltd is an Australian biotechnology company working in the field of oncolytic viruses, that is, viruses that preferentially infect and kill cancer cells. The company's oncolytic virus product, called Cavatak, is currently in clinical trials in metastatic melanoma and other cancers. The drug was granted Orphan Drug status in advanced melanoma in December 2005. In February 2018, Merck & Co. announced it would acquire Viralytics for AUD$502 million ($394 million).

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Xenotransplantation

Xenotransplantation (xenos- from the Greek meaning "foreign"), is the transplantation of living cells, tissues or organs from one species to another.

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Zicam

Zicam is a branded series of products marketed for cold and allergy relief whose original formulations included the element zinc.

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Redirects here:

CD54, ICAM-1 receptor, ICAM1, ICAM1 (gene), Intercellular adhesion molecule 1.

References

[1] https://en.wikipedia.org/wiki/ICAM-1

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