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International nonproprietary name

Index International nonproprietary name

The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient. [1]

1338 relations: Abafungin, Abanoquil, Abediterol, Abexinostat, Abitesartan, Ablukast, Abrilumab, Abunidazole, Acadesine, Acamprosate, Acaprazine, Acarbose, Acebrochol, Aceburic acid, Acecarbromal, Acedapsone, Acediasulfone, Acefurtiamine, Acefylline, Aceprometazine, Acetryptine, Aciclovir, Aclarubicin, Aclidinium bromide, Acridorex, Acriflavine, Adrafinil, Adrenaline, Adrenocorticotropic hormone (medication), Afamelanotide, Afegostat, Afoxolaner, Alectinib, Alendronic acid, Alentemol, Alfadolone, Alfuzosin, Alimadol, Alimemazine, Alirocumab, Aliskiren/amlodipine, Aliskiren/amlodipine/hydrochlorothiazide, Alisporivir, Alletorphine, Almecillin, Almorexant, Aloracetam, Alpha-Ethyltryptamine, Alpha-galactosidase, Alphacetylmethadol, ..., Alphamethadol, Alsactide, Alvocidib, Amadinone, Amezinium metilsulfate, Amfecloral, Amifampridine, Amixetrine, Amonafide, Amoscanate, Amosulalol, Amoxicillin, Amoxicillin/clavulanic acid, Amphetamine, Ampicillin/flucloxacillin, Amprolium, Amrinone, Amrubicin, Anamorelin, Anazocine, Andecaliximab, Anecortave acetate, Angiotensinamide, Anilopam, Ansofaxine, Apararenone, Aplaviroc, Apraclonidine, Apricitabine, Aranidipine, Arbekacin, Arfendazam, Arimoclomol, Arotinolol, Arsthinol, Artemotil, Arylsulfatase B, Asoprisnil, Asoprisnil ecamate, Astromicin, Atiprimod, Atovaquone/proguanil, Attention deficit hyperactivity disorder management, Atypical hemolytic uremic syndrome, Australian Approved Name, Aviptadil, Avitriptan, Axelopran, Axomadol, Azacitidine, Azacosterol, Azalanstat, Azastene, Azelnidipine, Azilsartan, Bacampicillin, Balofloxacin, Bambuterol, Barnidipine, Barusiban, Basimglurant, Batimastat, Becampanel, Beclometasone dipropionate, Befunolol, Bekanamycin, Bemotrizinol, Bendroflumethiazide, Benexate, Benfotiamine, Benidipine, Benorilate, Benproperine, Benralizumab, Benzbromarone, Benzenesulfonic acid, Benzhydrocodone, Benzthiazide, Bephenium hydroxynaphthoate, Berefrine, Besifloxacin, Besifovir, Beta-2 adrenergic receptor, Beta-adrenergic agonist, Beta2-adrenergic agonist, Betamethadol, Betamipron, Betrixaban, Bevantolol, Biapenem, Bibrocathol, Bictegravir, Bietaserpine, Bifemelane, Bifeprunox, Biopharmaceutical, Biricodar, Bisacodyl, Bisdisulizole disodium, Bisoctrizole, Bleselumab, Blontuvetmab, Bolandiol, Bopindolol, Bortezomib, Bosutinib, Bradanicline, Brazikumab, Brecanavir, Brentuximab vedotin, Brigatinib, Brilanestrant, Brimonidine/timolol, British Approved Name, British Pharmacopoeia, Brivanib alaninate, Brolucizumab, Bromisoval, Bromopride, Brontictuzumab, Bucetin, Budralazine, Bunazosin, Buparlisib, Bupropion, Burosumab, Butaxamine, Buthalital, Butidrine, Butinazocine, Butorphanol, Butyl cyanoacrylate, Cabotegravir, Cafedrine, Calcifediol, Calcipotriol, Calcipotriol/betamethasone dipropionate, Calcitriol, Calusterone, Camostat, Canakinumab, Candesartan, Candocuronium iodide, Cannabinoid receptor, Capeserod, Caplacizumab, Capromorelin, Capsaicin, Captodiame, Carbaryl, Carbenzide, Carbetocin, Carbocisteine, Carboprost, Carbuterol, Carfenazine, Carindacillin, Carmofur, Carotuximab, Carpronium chloride, Casokefamide, Casopitant, Caspofungin, Cefacetrile, Cefalexin, Cefaloglycin, Cefalonium, Cefalotin, Cefamandole, Cefapirin, Cefazaflur, Cefbuperazone, Cefcapene, Cefdaloxime, Cefmatilen, Cefminox, Cefovecin, Cefozopran, Cefpimizole, Cefradine, Cefroxadine, Ceftaroline fosamil, Cefteram, Ceftiolene, Cefuzonam, Cenicriviroc, Centanafadine, Cephalosporin, Cericlamine, Ceritinib, Cerivastatin, Ceronapril, Ceruletide, Cetraxate, Chemotherapy, Chloral betaine, Chlormethine, Chlormidazole, Chlortalidone, Chlorzoxazone, Cholecalciferol, Choline theophyllinate, Cianopramine, Ciclacillin, Ciclafrine, Ciclindole, Ciclosporin, Ciglitazone, Cilnidipine, Cilofungin, Cilomilast, Cimaterol, Cimemoxin, Cinacalcet, Cinanserin, Cinchocaine, Cingestol, Cinnamedrine, Cipemastat, Ciraparantag, Cisatracurium besilate, Cismadinone, Citicoline, Clamoxyquine, Clenoliximab, Clevidipine, Clevudine, Clidinium bromide, Clinofibrate, Clobetasone, Clodronic acid, Clofedanol, Clogestone, Clomegestone, Clomifenoxide, Cloperastine, Clorgiline, Clovoxamine, Cofetuzumab pelidotin, Cogazocine, Colestilan, Colestyramine, Colextran, Colforsin, Coluracetam, Compendium of Pharmaceuticals and Specialties, Conorfone, Controlled Substances Act, Corbadrine, Corticorelin, Corticotropin-releasing hormone, Crocetin, Croconazole, Cromakalim, Cromoglicic acid, Crotedumab, Cyclarbamate, Cyclopregnol, Cypenamine, Dacemazine, Dacuronium bromide, Dalbavancin, Danoprevir, Dantron, Dapagliflozin, Darbepoetin alfa, Dasolampanel, Dasotraline, Dénomination Commune Française, Decoglurant, Dectaflur, Delafloxacin, Delmadinone, Demeclocycline, Demecolcine, Demoxytocin, Denintuzumab mafodotin, Denominazione Comune Italiana, Denopamine, Denufosol, Depatuxizumab mafodotin, Depramine, Deserpidine, Desfesoterodine, Desmethylmoramide, Desonide, Dextroamphetamine, Dezocine, Diacerein, Diazinon, Diazoxide, Dicirenone, Dicoumarol, Difebarbamate, Difelikefalin, Difemetorex, Difenamizole, Difloxacin, Diflucortolone, Diiodohydroxyquinoline, Diltiazem, Dimemorfan, Dimenoxadol, Dimepheptanol, Dimepregnen, Dimethylaminoisopropanol, Dimethylamphetamine, Dimethyltubocurarinium chloride, Dimetotiazine, Diminazene, Dioxaphetyl butyrate, Dipivefrine, Dipraglurant, Diprophylline, Diridavumab, Disopyramide, Dithranol, Dizocilpine, Docosahexaenoic acid, Domagrozumab, Domoxin, Donitriptan, DOTA (chelator), Drinabant, Droloxifene, Dronabinol, Drotaverine, Droxidopa, Drug nomenclature, Drug policy of India, Duligotuzumab, Duvelisib, Duvortuxizumab, Edivoxetine, Efaproxiral, Efonidipine, EGTA (chemical), Elacestrant, Elafibranor, Elesclomol, Elezanumab, Eliglustat, Elinogrel, Eltrombopag, Emactuzumab, Embutramide, Emibetuzumab, Enantiopure drug, Enasidenib, Encenicline, Enciprazine, Endrisone, Enfuvirtide, Enocitabine, Enoticumab, Enoximone, Enoxolone, Enpiprazole, Ensulizole, Entrectinib, Enviomycin, Enzacamene, Epelsiban, Epirizole, Epoetin alfa, Epoetin beta, Epostane, Eprobemide, Ergoline, Ertugliflozin, Erythritol tetranitrate, Esaxerenone, Estradiol hexahydrobenzoate, Estramustine phosphate, Estrazinol, Estrofurate, Etabonate, Etacrynic acid, Etafedrine, Etamestrol, Etamiphylline, Etamivan, Etazepine, Ethylenediaminetetraacetic acid, Ethynerone, Etidronic acid, Etifelmine, Etifoxine, Etodroxizine, Etofamide, Etomidate, Etybenzatropine, Everolimus, Evofosfamide, Evogliptin, Ex-Rad, Examorelin, Ezlopitant, Fabomotizole, Falecalcitriol, Fanapanel, Fasudil, Faxeladol, Febarbamate, Fedotozine, Felbinac, Femoxetine, Fenbutrazate, Fencamfamin, Fenestrel, Fenethazine, Fenethylline, Fenisorex, Fenofibrate, Fenoverine, Fenpentadiol, Fenquizone, Fenretinide, Fenspiride, Fentonium bromide, Fenyramidol, Fesoterodine, Fevipiprant, Filenadol, Filorexant, Finerenone, Fingolimod, Firocoxib, Fispemifene, Fixed-dose combination (antiretroviral), Fletikumab, Florantyrone, Flotetuzumab, Flucetorex, Fluclorolone acetonide, Flucloxacillin, Fludeoxyglucose (18F), Fludroxycortide, Flugestone, Flumetasone, Flumexadol, Fluorometholone, Fluorouracil, Flupentixol, Fluralaner, Fluroxene, Fluvastatin, Folinic acid, Formebolone, Formetorex, Formocortal, Formoterol, Forodesine, Fosfluconazole, Fospropofol, Frakefamide, Fremanezumab, Frunevetmab, Funapide, Furosemide, Furostilbestrol, Fursultiamine, Fusafungine, Fusion protein, Futuximab, Gadobenic acid, Gadobutrol, Gadoteridol, Galactosidases, Galcanezumab, Gallopamil, Gamma-Linolenic acid, Ganciclovir, Gapicomine, Garenoxacin, Gedocarnil, Gefitinib, Gemfibrozil, Gemigliptin, Gemopatrilat, Generic drug, Generic name, Gepefrine, Gepotidacin, Gestaclone, Ghrelin, Gilvetmab, Gimsilumab, Gitoformate, Givinostat, Glecaprevir, Glemanserin, Glibornuride, Gliquidone, Glisoxepide, Glyclopyramide, Glycopyrronium bromide, Glymidine sodium, Gosogliptin, Growth hormone, Growth hormone therapy, Growth hormone–releasing hormone, Guanoclor, Gustav Ehrhart, Halocarban, Haloperidol, Hemolytic-uremic syndrome, Heptabarb, Hepzidine, Heroin, Hexapradol, Histamine dihydrochloride, Homarylamine, Homochlorcyclizine, Homotaurine, Humanized antibody, Hydrocodone/aspirin, Hydrocodone/ibuprofen, Hydromadinone, Hyoscine, Hypromellose, Ibafloxacin, Ibandronic acid, Ibazocine, Ibuprofen, Icaridin, Icodextrin, Idalopirdine, Idazoxan, Identifier, Idoxifene, Iferanserin, Ilomastat, Imagabalin, Imexon, Imgatuzumab, Imidafenacin, Imiquimod, ImmunoGen, Imolamine, Impromidine, Inaperisone, Incadronic acid, Inclacumab, Indacaterol, Indalpine, Indecainide, Indeloxazine, Indiplon, Indium (111In) altumomab pentetate, Indium (111In) biciromab, Indometacin, Indometacin farnesil, Inebilizumab, Influenza treatment, Iniparib, INN, Inosine pranobex, Insulin degludec, Intepirdine, Interferon alfa, Interferon beta-1a, Interferon type I, Interleukin, Iodocholesterol, Iodocyanopindolol, Iofetamine (123I), Ioflupane (123I), Iomazenil, Iopamidol, Ioversol, Ipamorelin, Ipragliflozin, Ipriflavone, Irampanel, Irbesartan, Isomethadone, Itolizumab, Itopride, Ixabepilone, Japanese Accepted Name, Ketanserin, Ketazocine, Ketocaine, Ketoconazole, Ketorfanol, Kitasamycin, L-DOPA, Lacosamide, Lactulose, Lafutidine, Lampalizumab, Lanadelumab, Landiolol, Landogrozumab, Laniquidar, Lanperisone, Lanreotide, Lapatinib, Lapisteride, Lapyrium, Laropiprant, Latrepirdine, Lavoltidine, Lebrikizumab, Leconotide, Lenzilumab, Leptacline, Lestaurtinib, Letermovir, Letolizumab, Levacetylmethadol, Levallorphan, Levamlodipine, Levoamphetamine, Levobupivacaine, Levofenfluramine, Levoketoconazole, Levomefolic acid, Levomepromazine, Levomethadone, Levomethamphetamine, Levomethorphan, Levorphanol, Levosalbutamol, Levosimendan, Licostinel, Lidanserin, Lidocaine, Lifastuzumab vedotin, Ligelizumab, Lilopristone, Linagliptin, Lirilumab, List of antineoplastic agents, List of chemical compounds with unusual names, List of drugs: 1-9, List of drugs: A-Ab, List of drugs: Ac, List of drugs: Ad-Ak, List of drugs: Al, List of drugs: Am, List of drugs: An-Ap, List of drugs: Aq-Ar, List of drugs: As-Az, List of drugs: Ba, List of drugs: Be, List of drugs: Bi-Bo, List of drugs: Br, List of drugs: Bs-Bz, List of drugs: C-Ca, List of drugs: Cb-Ce, List of drugs: Cf-Ch, List of drugs: Ci, List of drugs: Cj-Cl, List of drugs: Cm-Co, List of drugs: Cp-Cz, List of drugs: D-Dd, List of drugs: De, List of drugs: Df-Di, List of drugs: Do, List of drugs: Dr-Dy, List of drugs: E-El, List of drugs: Em-Ep, List of drugs: Eq-Es, List of drugs: Et, List of drugs: Eu-Ex, List of drugs: Fa, List of drugs: Fe, List of drugs: Fi, List of drugs: Fl, List of drugs: Fm-Ft, List of drugs: G, List of drugs: H-He, List of drugs: Hf-Hz, List of drugs: Ia-Il, List of drugs: Im-In, List of drugs: Io-Ip, List of drugs: Iq-Iv, List of drugs: J, List of drugs: K, List of drugs: La, List of drugs: Le, List of drugs: Lf-Ln, List of drugs: Lo, List of drugs: Ls-Ly, List of drugs: M-Md, List of drugs: Me-Meo, List of drugs: Mep-Mes, List of drugs: Met, List of drugs: Meu-Mi, List of drugs: Mo, List of drugs: Mp-My, List of drugs: N-Na, List of drugs: Nb-Nh, List of drugs: Ni, List of drugs: Nj-Nz, List of drugs: O-Op, List of drugs: Oq-Ow, List of drugs: Ox-Oz, List of drugs: P-Pa, List of drugs: Pb-Pe, List of drugs: Pf-Ph, List of drugs: Pi, List of drugs: Pj-Pra, List of drugs: Prb-Prn, List of drugs: Pro-Prz, List of drugs: Ps-Pz, List of drugs: Q, List of drugs: R-Rb, List of drugs: Re, List of drugs: Rf-Rz, List of drugs: S-Sd, List of drugs: Se-Sh, List of drugs: Si, List of drugs: Sj-So, List of drugs: Sp-Sub, List of drugs: Suc-Sul, List of drugs: Sum-Sz, List of drugs: T-Td, List of drugs: Te, List of drugs: Tf-Th, List of drugs: Ti, List of drugs: Tj-Tq, List of drugs: Tr-Tri, List of drugs: Trj-Tz, List of drugs: U, List of drugs: V-Ve, List of drugs: Vf-Vz, List of drugs: W, List of drugs: X, List of drugs: Y, List of drugs: Z, List of local anesthetics, List of pharmaceutical compound number prefixes, List of pharmaceutical manufacturers in the United Kingdom, List of psychiatric medications by condition treated, List of psychotropic medications, List of therapeutic monoclonal antibodies, List of veterinary drugs, Lobenzarit, Lomerizine, Lometraline, Lomevactone, Lomitapide, Lomustine, Lonaprisan, Long-acting beta-adrenoceptor agonist, Lopirazepam, Lorbamate, Lorediplon, Lormetazepam, Lornoxicam, Lorpiprazole, Losigamone, Loxoprofen, Lubiprostone, Lucimycin, Lucitanib, Lufuradom, Lulizumab pegol, Luminespib, Lumiracoxib, Lumretuzumab, Lundbeck, Lurosetron, Macrogol, Mafenide, Mafosfamide, Magaldrate, Maitansine, Malotilate, Management of HIV/AIDS, Manidipine, Mannomustine, Mannosulfan, Mapracorat, Maraviroc, Maropitant, MDMA, Mebhydrolin, Mecamylamine, Mecasermin rinfabate, Mecillinam, Meclizine, Meclocycline, Meclofenoxate, Medication package insert, Medrysone, Mefexamide, Mefruside, Meglutol, Meldonium, Melengestrol, Menabitan, Menatetrenone, Mepacrine, Mepiprazole, Mertansine, Mespirenone, Mesylate, Metaglycodol, Metahexamide, Metamfepramone, Metaraminol, Metformin, Methacholine, Methamphetamine, Methitural, Methylene blue, Methylnaltrexone, Methylphenobarbital, Meticrane, Metildigoxin, Metirosine, Metisazone, Metkefamide, Metofoline, Metogest, Metopimazine, Metrifonate, Metynodiol, Mexiletine, Micronomicin, Milacemide, Minamestane, Minaprine, Mipomersen, Miproxifene, Miravirsen, Mirikizumab, Miroprofen, Mitiglinide, Mitomycins, Mitotane, Mitozolomide, Mizoribine, Modimelanotide, Mofezolac, Momelotinib, Mometasone, Monomethyl auristatin E, Monomethyl auristatin F, Morforex, Motavizumab, Moxonidine, Mozavaptan, Murodermin, N-Acetylaspartylglutamic acid, N-Phenylacetyl-L-prolylglycine ethyl ester, Nadifloxacin, Nafamostat, Nafoxadol, Nafoxidine, Naftidrofuryl, Naftopidil, Naldemedine, Nalfurafine, Nalmexone, Naloxegol, Naltalimide, Naluzotan, Nateglinide, Necitumumab, Nedaplatin, Nelivaptan, Nepadutant, Nepicastat, Neridronic acid, Neticonazole, Nexeridine, Niacin, Niaprazine, Nicergoline, Nifekalant, Nifuroxazide, Nifurtoinol, Nimorazole, Nisobamate, Nisoldipine, Nitecapone, Nitisinone, Nitrofurazone, Nitromifene, Nomenclature of monoclonal antibodies, Noracymethadol, Nordazepam, Nordinone, Norepinephrine, Norepinephrine (medication), Norfenefrine, Normethadone, Norpipanone, Novartis v. Union of India & Others, Oblimersen, Ocfentanil, Octatropine methylbromide, Octotiamine, Odalasvir, Odanacatib, Olaflur, Oleclumab, Olmutinib, Olpadronic acid, Olprinone, Omacetaxine mepesuccinate, Omapatrilat, Omecamtiv mecarbil, Omega-3 carboxylic acids, Omiloxetine, Onapristone, Oportuzumab monatox, Oritavancin, Ortetamine, Orticumab, Osilodrostat, Otamixaban, Oxaflozane, Oxetacaine, Oxetorone, Oxifentorex, Oxilorphan, Oxipurinol, Oxogestone, Oxybuprocaine, Oxycodone/ibuprofen, Ozagrel, Ozenoxacin, Paclitaxel, Pacritinib, Palonosetron, Pamidronic acid, Pamrevlumab, Panipenem, Panitumumab, Panobacumab, Panomifene, Paracetamol, Paracetamol brand names, Pardoprunox, Parsatuzumab, Patritumab, Pazufloxacin, Peginesatide, Pemirolast, Penimepicycline, Pentafluranol, Pentobarbital, Pentoxyverine, Pentylenetetrazol, Peptide receptor radionuclide therapy, Perafensine, Perakizumab, Perflenapent, Perflubron, Periciazine, Pexacerfont, Pexastimogene devacirepvec, Phenacemide, Phenazone, Pheneturide, Pheniprazine, Pheniramine, Phenmetrazine, Phenobarbital, Phenylpiracetam, Picilorex, Piketoprofen, Pilsicainide, Pimobendan, Pinatuzumab vedotin, Pinaverium bromide, Pipamazine, Pipamperone, Pipazetate, Pipequaline, Pirarubicin, Piretanide, Piroctone olamine, Piroxicam, Pivagabine, Pivenfrine, Pivmecillinam, Pixantrone, Pizotifen, Plerixafor, Plicamycin, Plozalizumab, Polatuzumab vedotin, Polycarbophil calcium, Polyhexanide, Pomalidomide, Ponazuril, Ponesimod, Potassium canrenoate, Pozanicline, Pramocaine, Pranoprofen, Primidone, Prinaberel, Pristinamycin, Profenamine, Progabide, Propagermanium, Propantheline bromide, Propazepine, Propoxate, Propoxycaine, Propyliodone, Prostaglandin F2alpha, Prosultiamine, Proxorphan, Proxymetacaine, Pseudoephedrine, Pyroxamine, Quilizumab, Quinagolide, Quinethazone, Quinisocaine, Racemoramide, Radalbuvir, Radequinil, Radezolid, Radiopharmaceutical, Radiopharmacology, Radotinib, Ralfinamide, Ralpancizumab, Ramatroban, Ramoplanin, Ramosetron, Ranevetmab, Ranimustine, Raseglurant, Ravulizumab, Razobazam, Recombinant factor VIIa, Relamorelin, Remogliflozin etabonate, Renanolone, Repirinast, Reproterol, Retigabine, Ribavirin, Ridinilazole, Rifampicin, Rimantadine, Rimiterol, RINN, Riodipine, Risedronic acid, Ritanserin, Rivoglitazone, Robatumumab, Roflurane, Rolapitant, Romiplostim, Ropinirole, Ropivacaine, Rosmantuzumab, Rosonabant, Rosuvastatin, Roxibolone, RTI-55, Rubitecan, Sacubitril, Sacubitrilat, Salbutamol, Samidorphan, Sarafloxacin, Saroglitazar, Satavaptan, Satraplatin, Scleroderma, Selepressin, Selurampanel, Semapimod, Semuloparin sodium, Seneka Bibile, Sergliflozin etabonate, Seribantumab, Serlopitant, Setipiprant, Sevelamer, Silibinin, Silmitasertib, Silperisone, Siltuximab, Simeticone, Simtuzumab, Siponimod, Sirukumab, Sitafloxacin, Sitagliptin, Sivelestat, Sivifene, Sodium acetrizoate, Sodium apolate, Sodium aurothiomalate, Sodium dichloroisocyanurate, Sodium oxybate, Sodium picosulfate, Sofalcone, Sofituzumab vedotin, Solanezumab, Solifenacin, Solitomab, Sonidegib, Sorbinil, Sorivudine, Spirorenone, Spiroxasone, Sprifermin, Sri Lanka National Pharmaceuticals Policy, Stercuronium iodide, Stimulant, Streptozotocin, Sucroferric oxyhydroxide, Sufotidine, Sulbenicillin, Sulfafurazole, Sulfalene, Sulfamazone, Sulfametoxydiazine, Sulfametrole, Sulfapyridine, Sulfiram, Sulfisomidine, Suplatast tosilate, Suptavumab, Suvratoxumab, Tabimorelin, Tadalafil, Talampanel, Talaporfin, Taleranol, Tamtuvetmab, Tanaproget, Tanezumab, Taribavirin, Tavilermide, Tavolimab, Taxane, Tecemotide, Technetium (99mTc) pintumomab, Technetium (99mTc) sestamibi, Teflurane, Tegafur, Telcagepant, Telmisartan, Telmisartan/hydrochlorothiazide, Temoporfin, Teneligliptin, Tenofovir alafenamide, Terbogrel, Terfluranol, Terguride, Tert-Butylamine, Tesamorelin, Tesmilifene, Testosterone ketolaurate, Tetrabarbital, Tetroxoprim, Tetryzoline, Tezampanel, Tezepelumab, Thebacon, Theodrenaline, Thiazinamium metilsulfate, Thioacetazone, Thiomersal, Thiotepa, Thiotetrabarbital, Thyroid-stimulating hormone, Thyrotropin-releasing hormone, Tiabendazole, Tiamenidine, Tibulizumab, Tienilic acid, Tigestol, Tilapertin, Tilisolol, Tiludronic acid, Timepidium bromide, Tinabinol, Tioguanine, Tiomesterone, Tioxolone, Tipepidine, Tipifarnib, Tirofiban, Tiropramide, Tobramycin/dexamethasone, Toceranib, Tocolytic, Tofacitinib, Tofogliflozin, Tolciclate, Tolgabide, Tolnaftate, Tolonium chloride, Tolpiprazole, Tolrestat, Tolvaptan, Topiroxostat, Toripristone, Tranilast, Trazium, Trepipam, Trevogrumab, Trichlormethiazide, Triethylenetetramine, Trimedoxime bromide, Trimetaphan camsilate, Trimethoprim/polymyxin, Trioxifene, Tripamide, Triparanol, Triplatin tetranitrate, Trofosfamide, Tropanserin, Tropisetron, Trospium chloride, Tulobuterol, Tumor necrosis factor alpha, Tybamate, Ubenimex, Ufenamate, Ulimorelin, Ulobetasol, Ulocuplumab, Umirolimus, United States Adopted Name, Unoprostone, Uramustine, Uridine triacetate, Ursodeoxycholic acid, Vaborbactam, Valbenazine, Valnoctamide, Valperinol, Valsartan/hydrochlorothiazide, Vandetanib, Vandortuzumab vedotin, Vanucizumab, Vardenafil, Varlilumab, Vatalanib, Vedaclidine, Velusetrag, Vemurafenib, Venetoclax, Vernakalant, Vesnarinone, Vestipitant, Vilanterol, Vilaprisan, Vinflunine, Viqualine, Vobarilizumab, Voglibose, Volanesorsen, Volinanserin, Volixibat, Vorinostat, Vosoritide, Xantocillin, Xorphanol, Zafuleptine, Zatuximab, Zenazocine, Zibotentan, Zimelidine, Zindoxifene, Zofenopril, Zonampanel, Zorubicin, Zotarolimus, Zoxazolamine, Zuclomifene, 1,1,1,2,3,3,3-Heptafluoropropane, 1,1,1,2-Tetrafluoroethane, 1,2-Dichlorotetrafluoroethane, 11-Deoxycorticosterone, 11-Deoxycortisol, 2,5-Dimethoxy-4-bromoamphetamine, 3,4-Methylenedioxyamphetamine, 4-Aminopyridine. Expand index (1288 more) »

Abafungin

Abafungin (INN) is a broad-spectrum antifungal agent with a novel mechanism of action for the treatment of dermatomycoses.

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Abanoquil

Abanoquil (INN) is an α1-adrenergic receptor antagonist.

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Abediterol

Abediterol (INN; development codes AZD-0548 and LAS 100977) is a once-daily experimental drug candidate for the treatment of asthma and chronic obstructive pulmonary disease (COPD).

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Abexinostat

Abexinostat (INN, formerly PCI-24781) is an experimental drug candidate for cancer treatment.

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Abitesartan

Abitesartan (INN) is an Angiotensin II receptor antagonist.

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Ablukast

Ablukast (INN) is a leukotriene antagonist which has applications in the treatment of inflammatory skin conditions.

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Abrilumab

Abrilumab (AMG 181) (INN) is a monoclonal antibody designed for the treatment of inflammatory bowel disease, ulcerative colitis, and Crohn's disease.

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Abunidazole

Abunidazole (INN) is a nitroimidazole antifungal drug.

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Acadesine

Acadesine (INN), also known as 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside, AICA-riboside, and AICAR, is an AMP-activated protein kinase activator which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating other disorders such as diabetes.

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Acamprosate

Acamprosate, sold under the brand name Campral, is a medication used along with counselling to treat alcohol dependence.

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Acaprazine

Acaprazine (INN) is an anxiolytic and "adrenolytic" drug of the phenylpiperazine group that was never marketed.

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Acarbose

Acarbose (INN) is an anti-diabetic drug used to treat diabetes mellitus type 2 and, in some countries, prediabetes.

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Acebrochol

Acebrochol (INN), also known as cholesteryl acetate dibromide or 5α,6β-dibromocholestan-3β-ol acetate, is a neuroactive steroid which was described as a sedative and hypnotic but was never marketed.

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Aceburic acid

Aceburic acid (INN), also known as 4-acetoxybutanoic acid or 4-hydroxybutyric acid acetate, is drug described as an analgesic which was never marketed.

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Acecarbromal

Acecarbromal (INN) (brand names Sedamyl, Abasin, Carbased, Paxarel, Sedacetyl, numerous others), also known as acetylcarbromal and acetyladalin, is a hypnotic and sedative drug of the ureide (acylurea) group discovered by Bayer in 1917 that was formerly marketed in the United States and Europe.

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Acedapsone

Acedapsone (INN) is an antimicrobial drug, which also has antimalarial activity.

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Acediasulfone

Acediasulfone (INN) is an antimicrobial drug, which also has antimalarial activity.

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Acefurtiamine

Acefurtiamine (INN) is a vitamin B1 analog in a manner similar to the GABAergic activity of the thiamine derivative clomethiazole.

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Acefylline

Acefylline (INN), also known as acetyloxytheophylline, is a stimulant drug of the xanthine chemical class.

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Aceprometazine

Aceprometazine (INN) is a phenothiazine derivative prescription drug with neuroleptic and anti-histamine properties.

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Acetryptine

Acetryptine (INN) (developmental code name W-2965-A), also known as 5-acetyltryptamine (5-AT), is a drug described as an antihypertensive agent which was never marketed.

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Aciclovir

Aciclovir (ACV), also known as acyclovir, is an antiviral medication.

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Aclarubicin

Aclarubicin (INN) or aclacinomycin A is an anthracycline drug that is used in the treatment of cancer.

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Aclidinium bromide

Aclidinium bromide (INN) is a long-acting, inhaled muscarinic antagonist (LAMA) approved in the US on July 24, 2012 as a maintenance treatment for chronic obstructive pulmonary disease (COPD).

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Acridorex

Acridorex (INN; BS 7573a) is an amphetamine which was investigated as an anorectic but does not appear to have ever been marketed.

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Acriflavine

Acriflavine (INN: acriflavinium chloride) is a topical antiseptic.

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Adrafinil

Adrafinil (INN; brand name Olmifon) is a eugeroic that was formerly used in France to promote alertness, attention, wakefulness, mood, and other parameters, particularly in the elderly.

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Adrenaline

Adrenaline, also known as adrenalin or epinephrine, is a hormone, neurotransmitter, and medication.

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Adrenocorticotropic hormone (medication)

Adrenocorticotropic hormone is used as a medication and as diagnostic agent in the ACTH stimulation test.

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Afamelanotide

Afamelanotide ((INN) (brand name Scenesse), also known as melanotan I (or melanotan-1), originally developed at the University of Arizona and now by Clinuvel Pharmaceuticals, is a synthetic peptide and analogue of the naturally occurring melanocortin peptide hormone α-melanocyte stimulating hormone (α-MSH) that has been shown to induce the production of darkening dermal pigmentation through melanogenesis and thereby subsequently reduce sun (UV) damage to UV light-exposed skin in preliminary research and human clinical trials. Its amino acid sequence is Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2, and it is additionally known as -α-MSH, which is sometimes abbreviated as NDP-MSH or NDP-α-MSH (especially in the scientific literature). Afamelanotide is the International Nonproprietary Name for the molecule α-MSH initially researched and developed as melanotan-1 and later, CUV1647 (by Clinuvel). A marketing trade name for one brand of afamelanotide was approved in 2010 by the European Medicines Agency (EMA) Name Review Group (NRG) and the agency's Committee for Medicinal Products for Human Use (CHMP) as Scenesse (pronounced "sen-esse"). On May 5, 2010 the Italian Medicines Agency (AIFA, or Agenzia Italiana del Farmaco) became the first governmental health organization ever (even before the drug received approval in Europe) to authorize afamelanotide as a medicine for therapeutic treatment of Italian citizens to reduce painful dermal photosensitivity stemming from the orphan disease erythropoietic protoporphyria (EPP). This approval allowed the drug to be immediately available for prescription in Italy and reimbursable under the country's national health system. Authorities in Switzerland have also allowed prescription of the drug for EPP with reimbursement approved by two unnamed insurers. Afamelanotide is currently being trialed in the form of a "grain of rice"-sized bioabsorbable subcutaneous implant as a potential therapeutic photoprotection-inducing agent for a series of light-related skin indications as well as a potential dermal repigmentation agent for vitiligo. Afamelanotide, as of October 24, 2014, has been approved by the EMA in Europe for the treatment of EPP. Clinuvel now intends to seek approval of afamelanotide in the United States. Unlicensed and untested powders sold as "melanotan" are found on the Internet and are reported to be used by tens of thousands of members of the general public for sunless tanning. Multiple regulatory bodies have warned consumers that the peptides may be unsafe and ineffective in usage, with one regulatory agency warning that consumers who purchase any product labeled "melanotan" risk buying a counterfeit drug. Clinuvel Pharmaceuticals, the developer of afamelanotide, and medical researchers have warned consumers that counterfeit products sold using the names "melanotan I and II", could "pose a hazard to public health". on counterfeit products. February 10, 2009. Clinuvel has stated publicly that products sold online as "melanotan" are not afamelanotide.

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Afegostat

Afegostat (INN; also known as isofagomine; planned trade name Plicera) was an experimental drug for the treatment of certain forms of Gaucher's disease that was being developed by Amicus Therapeutics and Shire plc until a failed clinical trial in 2009 led to termination of its development.

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Afoxolaner

Afoxolaner (INN) is an insecticide and acaricide used in dogs.

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Alectinib

Alectinib (INN, marketed as Alecensa) is an oral drug that blocks the activity of anaplastic lymphoma kinase (ALK) and is used to treat non-small-cell lung cancer (NSCLC).

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Alendronic acid

Alendronic acid (INN) or alendronate sodium, sold under the trade name Fosamax among others, is a bisphosphonate drug used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.

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Alentemol

Alentemol (INN) (developmental code name U-66444B), or alentamol, is a selective dopamine autoreceptor agonist described as an antipsychotic, which was never marketed.

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Alfadolone

Alfadolone (INN), or alphadolone is a neuroactive steroid and general anesthetic.

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Alfuzosin

Alfuzosin (INN, provided as the hydrochloride salt) is a pharmaceutical drug of the α1 blocker class.

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Alimadol

Alimadol (INN; A-4020) is an opioid analgesic related to methadone which was never marketed.

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Alimemazine

Alimemazine (INN), also known as trimeprazine,; brand names Nedeltran, Panectyl, Repeltin, Therafene, Theraligene, Theralen, Theralene, Vallergan, Vanectyl, and Temaril), commonly provided as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting as an antihistamine). It also acts as a sedative, hypnotic, and antiemetic for prevention of motion sickness. Although it is structurally related to drugs such as chlorpromazine, it is not used as an antipsychotic. In the Russian Federation, it is marketed under the brand name Teraligen for the treatment of anxiety disorders (including GAD), organic mood disorders, sleep disturbances, personality disorders accompanied by asthenia and depression, somatoform autonomic dysfunction and various neuroses. Alimemazine is not approved for use in humans in the United States. The combination of alimemazine and prednisolone (commonly sold under the brand name Temaril-P) is licensed as an antipruritic and antitussive in dogs.

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Alirocumab

Alirocumab (trade name Praluent), World Health Organization is a biopharmaceutical drug approved by the FDA on July 24, 2015 as a second line treatment for high cholesterol for adults whose cholesterol is not controlled by diet and statin treatment.

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Aliskiren/amlodipine

The drug combination aliskiren/amlodipine (INNs, trade name Tekamlo) is an antihypertensive.

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Aliskiren/amlodipine/hydrochlorothiazide

The drug combination aliskiren/amlodipine/hydrochlorothiazide (INNs, trade name Amturnide) is an antihypertensive approved by the U.S. Food and Drug Administration (FDA) on December 21, 2010.

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Alisporivir

Alisporivir (INN), or Debio 025, DEB025, (or UNIL-025) is a cyclophilin inhibitor.

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Alletorphine

Alletorphine (INN; M-218, R&S-218-M), or N-allylnoretorphine, is an opioid analgesic of the oripavine series which was never marketed.

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Almecillin

Almecillin (INN), also known as penicillin O, is a penicillin that is similar in antibiotic action to penicillin G. It is obtained by isolation from Penicillium chrysogenum.

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Almorexant

Almorexant (INN, codenamed ACT-078573) is an orexin antagonist, functioning as a competitive receptor antagonist of the OX1 and OX2 orexin receptors, which was being developed by the pharmaceutical companies Actelion and GSK for the treatment of insomnia.

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Aloracetam

Aloracetam (INN) is a drug described as a nootropic which is closely related to, but technically not of (as it lacks a pyrrolidone ring), the racetam family of compounds.

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Alpha-Ethyltryptamine

α-Ethyltryptamine (αET, AET), also known as etryptamine (INN, BAN, USAN), is a psychedelic, stimulant, and entactogenic drug of the tryptamine class.

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Alpha-galactosidase

Alpha-galactosidase is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins.

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Alphacetylmethadol

Alphacetylmethadol (INN), or α-acetylmethadol (AAM), is a synthetic opioid analgesic.

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Alphamethadol

Alphamethadol (INN), or α-methadol, also known as alfametadol, is a synthetic opioid analgesic.

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Alsactide

Alsactide (INN) (brand name Synchrodyn 1-17 or simply Synchrodyn, former development code name Hoechst 433), also known as alisactide, is a synthetic peptide and analogue of adrenocorticotropic hormone (ACTH) which is used in Italy as a diagnostic agent in kidney function for adrenal insufficiency.

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Alvocidib

Alvocidib (INN; also known as Flavopiridol) is a flavonoid alkaloid CDK9 kinase inhibitor under clinical development for the treatment of acute myeloid leukemia, by Tolero Pharmaceuticals, Inc.

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Amadinone

Amadinone (INN), also known as 19-norchlormadinone, is a steroidal progestin of the 19-norprogesterone and 17α-hydroxyprogesterone groups that was synthesized and characterized in 1968 but was never marketed.

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Amezinium metilsulfate

Amezinium metilsulfate (INN, trade name Regulton) is a sympathomimetic drug used for the treatment of low blood pressure.

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Amfecloral

Amfecloral (INN), also known as amphecloral (USAN), is a stimulant drug of the phenethylamine and amphetamine chemical classes that was used as an appetite suppressant under the trade name Acutran, but is now no longer marketed.

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Amifampridine

Amifampridine (pyridine-3,4-diamine, 3,4-diaminopyridine, 3,4-DAP) is used as a drug, predominantly in the treatment of a number of rare muscle diseases. The free base form of the drug has been used to treat congenital myasthenic syndromes and Lambert–Eaton myasthenic syndrome (LEMS) through compassionate use programs since the 1990s and was recommended as a first line treatment for LEMS in 2006, using ad hoc forms of the drug, since there was no marketed form. Around 2000 doctors at Assistance Publique – Hôpitaux de Paris created a phosphate salt form, which was developed through a series of companies ending with BioMarin Pharmaceutical which obtained European approval in 2009 under the trade name Firdapse, and which licensed the US rights to Catalyst Pharmaceuticals in 2012. As of January 2017, Catalyst and another US company, Jacobus Pharmaceuticals, which had been manufacturing the free base form and giving it away for free since the 1990s, were racing to obtain FDA approval for their versions first; the company that obtained the approval would have seven years of marketing exclusivity. Amifampridine phosphate has orphan drug status in the EU for Lambert–Eaton myasthenic syndrome and Catalyst holds both an orphan designation and a breakthrough therapy designation in the US..

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Amixetrine

Amixetrine (INN) (brand name Somagest; developmental code name CERM-898) is a drug that was formerly marketed in France but is now no longer sold.

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Amonafide

Amonafide (originally AS1413) (INN, trade names Quinamed and Xanafide) is a drug that is being studied in the treatment of cancer.

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Amoscanate

Amoscanate (INN), also known as nithiocyamine, is an experimental anthelmintic agent of the arylisothiocyanate class which was found to be highly effective in animals against the four major species of schistosomes which infect humans, and is also highly active against hookworm infection.

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Amosulalol

Amosulalol (INN) is a beta blocker.

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Amoxicillin

Amoxicillin, also spelled amoxycillin, is an antibiotic useful for the treatment of a number of bacterial infections.

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Amoxicillin/clavulanic acid

Amoxicillin/clavulanic acid, also known as co-amoxiclav, is an antibiotic useful for the treatment of a number of bacterial infections.

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Amphetamine

Amphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity.

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Ampicillin/flucloxacillin

Ampicillin/flucloxacillin (INNs) or co-fluampicil (BAN) is a combination drug of the two β-lactam antibiotics Ampicillin and flucloxacillin, sold under the tradenames Magnapen and Infectrin.

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Amprolium

Amprolium is the organic compound sold as a coccidiostat used in poultry.

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Amrinone

Amrinone (INN) or inamrinone (USAN, changed in 2000 to prevent confusion with amiodarone), trade name Inocor, is a pyridine phosphodiesterase 3 inhibitor.

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Amrubicin

Amrubicin (INN; previously known as SM-5887) is an anthracycline used in the treatment of lung cancer.

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Anamorelin

Anamorelin (INN) (developmental code names ONO-7643, RC-1291, ST-1291), also known as anamorelin hydrochloride (USAN, JAN), is a non-peptide, orally-active, centrally-penetrant, selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) with appetite-enhancing and anabolic effects which is under development by Helsinn Healthcare SA for the treatment of cancer cachexia and anorexia.

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Anazocine

Anazocine (INN; CS-307), also known as azabicyclane, is an opioid analgesic of the morphan/benzomorphan family developed in the middle 1960s in the United States which was never marketed.

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Andecaliximab

Andecaliximab (GS-5745) (INN) is a humanized monoclonal antibody designed for the treatment of cancer and inflammatory diseases.

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Anecortave acetate

Anecortave (rINN) is a novel angiogenesis inhibitor used in the treatment of the exudative (wet) form of age-related macular degeneration.

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Angiotensinamide

Angiotensinamide (INN; BAN and USAN angiotensin amide) is a potent vasoconstrictor used as a cardiac stimulant.

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Anilopam

Anilopam (INN; PR 786-723) is an opioid analgesic of the benzazepine class which was developed by Pentwell in the 1960s but was never marketed.

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Ansofaxine

Ansofaxine hydrochloride (INN) (former developmental code names LY03005, LPM570065), also known as 4-methylbenzoate desvenlafaxine hydrochloride, is a serotonin-norepinephrine-dopamine reuptake inhibitor that is under development by Luye Pharma Group for the treatment of major depressive disorder.

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Apararenone

Apararenone (INN) (developmental code name MT-3995) is a nonsteroidal antimineralocorticoid which is under development by Mitsubishi Tanabe Pharma for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis.

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Aplaviroc

Aplaviroc (INN, codenamed AK602 and GSK-873140) is a CCR5 entry inhibitor that belongs to a class of 2,5-diketopiperazines developed for the treatment of HIV infection.

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Apraclonidine

Apraclonidine (INN), also known under the brand name Iopidine, is a sympathomimetic used in glaucoma therapy.

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Apricitabine

Apricitabine (INN, codenamed AVX754 and SPD754, sometimes abbreviated to ATC) is an experimental nucleoside reverse transcriptase inhibitor (NRTI) against HIV.

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Aranidipine

Aranidipine (INN, trade name Sapresta) is a calcium channel blocker.

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Arbekacin

Arbekacin (INN) is a semisynthetic aminoglycoside antibiotic.

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Arfendazam

Arfendazam (INN) is a drug which is a benzodiazepine derivative.

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Arimoclomol

Arimoclomol (INN; originally codenamed BRX-345, which is a citrate salt formulation of BRX-220) is an experimental drug developed by CytRx Corporation, a biopharmaceutical company based in Los Angeles, California.

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Arotinolol

Arotinolol (INN, marketed under the tradename Almarl) is a medication in the class of mixed alpha/beta blockers.

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Arsthinol

Arsthinol (INN) is an antiprotozoal agent.

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Artemotil

Artemotil (INN; also known as β-arteether), is a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant ''Plasmodium falciparum'' malaria and cerebral malaria cases.

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Arylsulfatase B

Arylsulfatase B (N-acetylgalactosamine-4-sulfatase, chondroitinsulfatase, chondroitinase, acetylgalactosamine 4-sulfatase, N-acetylgalactosamine 4-sulfate sulfohydrolase) is an enzyme associated with mucopolysaccharidosis VI (Maroteaux–Lamy syndrome).

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Asoprisnil

Asoprisnil (INN; developmental code name J-867) is a synthetic, steroidal selective progesterone receptor modulator that was under development by Schering and TAP Pharmaceutical Products for the treatment of uterine fibroids.

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Asoprisnil ecamate

Asoprisnil ecamate (INN) (developmental code name J-956) is a synthetic, steroidal selective progesterone receptor modulator (SPRM) which was under development for the treatment of endometriosis, uterine fibroids, and menopausal symptoms but was discontinued.

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Astromicin

Astromicin (INN)(also frequently referenced in scientific journal articles as compounds Fortimicin A/B) is an aminoglycoside antibiotic.

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Atiprimod

Atiprimod (INN, codenamed SK&F106615) is a substance being studied in the treatment of certain multiple myelomas and other advanced cancers.

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Atovaquone/proguanil

The drug combination atovaquone/proguanil (INNs, trade names Malarone, Malanil) is an antimalarial medication used in both the treatment and prevention of malaria.

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Attention deficit hyperactivity disorder management

Attention deficit hyperactivity disorder management options are evidence-based practices with established treatment efficacy for ADHD.

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Atypical hemolytic uremic syndrome

Atypical hemolytic uremic syndrome (aHUS) is an extremely rare, life-threatening, progressive disease that frequently has a genetic component.

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Australian Approved Name

An Australian Approved Name (AAN) is a generic drug name set by the TGA for use in Australia.

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Aviptadil

Aviptadil (INN) is an analog of vasoactive intestinal polypeptide (VIP) for the treatment of erectile dysfunction.

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Avitriptan

Avitriptan (INN) (code name BMS-180,048) is an antimigraine drug of the triptan family which was never marketed.

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Axelopran

Axelopran (INN, USAN) (developmental code name TD-1211) is a drug which is under development by Theravance Biopharma for the treatment of opioid-induced constipation.

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Axomadol

Axomadol (INN, USAN) (code name EN3324) is a synthetic, centrally-acting opioid analgesic of the benzenoid class which was under investigation by Endo Pharmaceuticals in collaboration with Grünenthal for the treatment of chronic, moderate to severe lower back pain and arthrosis.

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Azacitidine

Azacitidine (INN; trade name Vidaza) is a chemical analog of cytidine, a nucleoside in DNA and RNA.

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Azacosterol

Azacosterol (INN), or azacosterol hydrochloride (USAN) (brand name Ornitrol), also known as 20,25-diazacholesterol, is a cholesterol-lowering drug (hypocholesteremic) which was marketed previously but has since been discontinued. It is also an avian chemosterilant used to control the pest pigeon population via inducing sterility. The drug is a sterol and derivative of cholesterol in which two carbon atoms have been replaced with nitrogen atoms. Azacosterol acts as an inhibitor of 24-dehydrocholesterol reductase (24-DHCR), preventing the formation of cholesterol from desmosterol. Although it primarily acts to inhibit 24-DHCR, the drug also inhibits other steps in cholesterol biosynthesis. The anti-fertility effects of the drug in birds are mediated by inhibition of steroid hormone production, steroid hormones being synthesized from cholesterol. Due to prevention of the metabolism of desmosterol, the drug causes it to accumulate, in turn producing side effects such as hyperkeratosis, particularly of the palms and soles.

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Azalanstat

Azalanstat (INN, codenamed RS-21607) is an anti-obesity drug acting as a lanosterol 14α-demethylase inhibitor.

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Azastene

Azastene (INN, USAN) (developmental code name WIN-17625) is a steroidogenesis inhibitor described as a contraceptive and abortifacient which was never marketed.

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Azelnidipine

Azelnidipine (INN; marketed under the brand name CalBlock — カルブロック) is a dihydropyridine calcium channel blocker.

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Azilsartan

Azilsartan (INN) is an angiotensin II receptor antagonist used in the treatment of hypertension, developed by Takeda.

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Bacampicillin

Bacampicillin (INN) is a penicillin antibiotic.

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Balofloxacin

Balofloxacin (INN) is a fluoroquinolone antibiotic.

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Bambuterol

Bambuterol (INN) is a long-acting β adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.

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Barnidipine

Barnidipine (INN) or mepirodipine is a calcium channel blocker.

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Barusiban

Barusiban (INN) (code name FE-200440) is a non-peptide drug which is among the most potent and selective oxytocin receptor antagonists known.

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Basimglurant

Basimglurant (INN) (developmental code names RG-7090, RO-4917523) is a negative allosteric modulator of the mGlu5 receptor which is under development by Roche and Chugai Pharmaceutical for the treatment of treatment-resistant depression (as an adjunct) and fragile X syndrome.

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Batimastat

Batimastat (INN/USAN, codenamed BB-94) is an anticancer drug that belongs to the family of drugs called angiogenesis inhibitors.

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Becampanel

Becampanel (INN) (code name AMP397) is a quinoxalinedione derivative drug which acts as a competitive antagonist of the AMPA receptor (IC50.

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Beclometasone dipropionate

Beclometasone dipropionate, also spelled beclomethasone dipropionate and sold under the brand name Qvar among others, is a steroid medication.

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Befunolol

Befunolol (INN) is a beta blocker with intrinsic sympathomimetic activity used in the management of open-angle glaucoma.

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Bekanamycin

Bekanamycin (INN, or kanamycin B) is an aminoglycoside antibiotic.

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Bemotrizinol

Bemotrizinol (INN/USAN, INCI bis-ethylhexyloxyphenol methoxyphenyl triazine) is an oil-soluble organic compound that is added to sunscreens to absorb UV rays.

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Bendroflumethiazide

Bendroflumethiazide (INN), formerly bendrofluazide (BAN), trade name Aprinox, is a thiazide diuretic used to treat hypertension.

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Benexate

Benexate (INN) is a drug used in the treatment of acid-related disorders.

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Benfotiamine

Benfotiamine (rINN, or S-benzoylthiamine O-monophosphate) is a synthetic S-acyl derivative of thiamine (vitamin B1).

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Benidipine

Benidipine (INN), also known as Benidipinum or benidipine hydrochloride, is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension).

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Benorilate

Benorilate (INN), or benorylate, is an ester-linked codrug of aspirin with paracetamol.

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Benproperine

Benproperine (INN) is a cough suppressant.

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Benralizumab

Benralizumab (INN, trade name Fasenra) is a monoclonal antibody which developed by MedImmune for the treatment of asthma.

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Benzbromarone

Benzbromarone (INN) is a uricosuric agent and non-competitive inhibitor of xanthine oxidase used in the treatment of gout, especially when allopurinol, a first-line treatment, fails or produces intolerable adverse effects.

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Benzenesulfonic acid

Benzenesulfonic acid (conjugate base benzenesulfonate) is an organosulfur compound with the formula C6H5SO3H.

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Benzhydrocodone

Benzhydrocodone (INN) (contracted from '''benz'''oate-hydrocodone) is a opioid prodrug of the morphinan class.

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Benzthiazide

Benzthiazide (BAN/INN, also known as benzothiazide; trade names Aquatag, Dihydrex, Diucen, Edemax, Exna, Foven and others Retrieved on August 29, 2008 through Google Book Search.) is a thiazide diuretic used in the treatment of high blood pressure and edema.

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Bephenium hydroxynaphthoate

Bephenium hydroxynaphthoate (INN, trade names Alcopara, Alcopar, Befenium, Debefenium, Francin, Nemex) is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.

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Berefrine

Berefrine (INN, USAN), also known as burefrine, is a sympathomimetic and mydriatic agent that was never marketed.

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Besifloxacin

Besifloxacin (INN/USAN) is a fourth-generation fluoroquinolone antibiotic.

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Besifovir

Besifovir (INN) is an investigational medication to treat hepatitis B virus (HBV) infection.

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Beta-2 adrenergic receptor

The beta-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that interacts with (binds) epinephrine, a hormone and neurotransmitter (ligand synonym, adrenaline) whose signaling, via a downstream L-type calcium channel interaction, mediates physiologic responses such as smooth muscle relaxation and bronchodilation.

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Beta-adrenergic agonist

Beta adrenergic agonists or beta agonists are medications that relax muscles of the airways, which widen the airways and result in easier breathing.

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Beta2-adrenergic agonist

β2 (beta2) adrenergic receptor agonists, also known as adrenergic β2 receptor agonists, are a class of drugs that act on the β2 adrenergic receptor.

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Betamethadol

Betamethadol (INN), or β-methadol, also known as betametadol, is a synthetic opioid analgesic.

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Betamipron

Betamipron (INN) or N-benzoyl-β-alanine is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity.

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Betrixaban

Betrixaban (INN; trade name Bevyxxa; development code PRT-054,021) is an anticoagulant drug which acts as a direct factor Xa inhibitor.

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Bevantolol

Bevantolol (INN) was a drug candidate for angina and hypertension that acted as both a beta blocker and a calcium channel blocker.

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Biapenem

Biapenem (INN) is a carbapenem antibiotic.

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Bibrocathol

Bibrocathol (INN, trade names Noviform and Posiformin) is the substance 4,5,6,7-Tetrabrom-1,3,2-benzodioxabismol-2-ol.

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Bictegravir

Bictegravir (INN; formerly known as GS-9883) is an investigational new drug of the integrase inhibitor class that was discovered by scientists at Gilead Sciences; in vitro and clinical results were presented by Gilead in the summer of 2016.

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Bietaserpine

Bietaserpine (INN), or 1-diaminoethylreserpine, is a derivative of reserpine used as an antihypertensive agent.

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Bifemelane

Bifemelane (INN) (Alnert, Celeport), or bifemelane hydrochloride (JAN), also known as 4-(O-benzylphenoxy)-N-methylbutylamine, is an antidepressant and cerebral activator that is widely used in the treatment of cerebral infarction patients with depressive symptoms in Japan, and in the treatment of senile dementia as well.

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Bifeprunox

Bifeprunox (INN) (code name DU-127,090) is an atypical antipsychotic which, similarly to aripiprazole, combines minimal D2 receptor agonism with serotonin receptor agonism.

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Biopharmaceutical

A biopharmaceutical, also known as a biologic(al) medical product, biological, or biologic, is any pharmaceutical drug product manufactured in, extracted from, or semisynthesized from biological sources.

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Biricodar

Biricodar (INN, codename VX-710) was a pharmaceutical drug under development by Vertex Pharmaceuticals to help treat ovarian cancer patients, that never reached the market.

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Bisacodyl

Bisacodyl (INN) is an organic compound that is used as a stimulant laxative drug.

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Bisdisulizole disodium

Bisdisulizole disodium (INN/USAN, trade name Neo Heliopan AP, INCI disodium phenyl dibenzimidazole tetrasulfonate) is a water-soluble organic compound which is added to sunscreens to absorb UVA rays.

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Bisoctrizole

Bisoctrizole (INN/USAN, marketed by BASF as Tinosorb M and by MPI as Milestab 360, INCI methylene bis-benzotriazolyl tetramethylbutylphenol) is a benzotriazole-based organic compound that is added to sunscreens to absorb UV rays.

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Bleselumab

Bleselumab (INN) (ASKP1240) is a human monoclonal antibody designed for the prevention of organ transplant rejection.

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Blontuvetmab

Blontuvetmab (AT-004) (INN, trade name Blontress) is a veterinary monoclonal antibody.

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Bolandiol

Bolandiol (INN), also known as 19-nor-4-androstenediol, estr-4-en-3β,17β-diol, or 3β-dihydronandrolone, is an anabolic-androgenic steroid (AAS) that was never marketed.

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Bopindolol

Bopindolol (INN) is a beta blocker.

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Bortezomib

Bortezomib (BAN, INN and USAN; marketed as Velcade by Takeda Oncology; Chemobort by Cytogen and Bortecad by Cadila Healthcare) is an anti-cancer drug and the first therapeutic proteasome inhibitor to be used in humans.

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Bosutinib

Bosutinib (rINN/USAN; codenamed SKI-606, marketed under the trade name Bosulif) is a small molecule BCR-ABL and src tyrosine kinase inhibitor used for the treatment of chronic myelogenous leukemia.

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Bradanicline

Bradanicline (INN, code name TC-5619) is a drug which was being developed by Targacept that acts as a partial agonist at the α7 subtype of the neural nicotinic acetylcholine receptors.

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Brazikumab

Brazikumab (MEDI2070) (INN) is a human monoclonal antibody designed for the treatment of Crohn's disease.

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Brecanavir

Brecanavir (INN; codenamed GW640385) is a protease inhibitor which has been studied for the treatment of HIV.

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Brentuximab vedotin

Brentuximab vedotin (INN, trade name Adcetris) is an antibody-drug conjugate medication used to treat relapsed or refractory Hodgkin lymphoma (HL) and systemic anaplastic large cell lymphoma (ALCL).

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Brigatinib

Brigatinib (INN; marketed as Alunbrig) is an investigational small-molecule targeted cancer therapy being developed by ARIAD Pharmaceuticals, Inc.

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Brilanestrant

Brilanestrant (INN) (developmental code names GDC-0810, ARN-810, RG-6046, RO-7056118) is a nonsteroidal combined selective estrogen receptor modulator (SERM) and selective estrogen receptor degrader (SERD) that was discovered by Aragon Pharmaceuticals and was under development by Genentech for the treatment of locally advanced or metastatic estrogen receptor (ER)-positive breast cancer.

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Brimonidine/timolol

Brimonidine/timolol (INNs, trade name Combigan) are combination eye drops indicated for the treatment of glaucoma.

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British Approved Name

A British Approved Name (BAN) is the official non-proprietary or generic name given to a pharmaceutical substance, as defined in the British Pharmacopoeia (BP).

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British Pharmacopoeia

The British Pharmacopoeia (BP) is the national pharmacopoeia of the United Kingdom.

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Brivanib alaninate

Brivanib alaninate (INN/USAN) also known as BMS-582664 is an investigational, anti-tumorigenic drug for oral administration.

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Brolucizumab

Brolucizumab (INN) is a humanized monoclonal antibody designed for the treatment of wet age-related macular degeneration.

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Bromisoval

Bromisoval (INN), commonly known as bromovalerylurea, is a hypnotic and sedative of the bromoureide group discovered by Knoll in 1907 and patented in 1909.

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Bromopride

Bromopride (INN) is a dopamine antagonist with prokinetic properties widely used as an antiemetic, closely related to metoclopramide.

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Brontictuzumab

Brontictuzumab (OMP-52M51) (INN) is a humanized monoclonal antibody designed for the treatment of cancer.

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Bucetin

Bucetin (INN, BAN) is an analgesic and antipyretic that is no longer marketed.

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Budralazine

Budralazine (INN) is a vasodilator.

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Bunazosin

Bunazosin (INN) is an alpha 1 antagonist.

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Buparlisib

Buparlisib (INN, codenamed BKM120) is an investigational small molecule orally-available pan-class I phosphoinositide 3-kinase inhibitor.

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Bupropion

Bupropion, sold under the brand names Wellbutrin and Zyban among others, is a medication primarily used as an antidepressant and smoking cessation aid.

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Burosumab

Burosumab (INN, trade name Crysvita) known as KRN23 is a human monoclonal antibody designed for the treatment of X-linked hypophosphatemia.

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Butaxamine

Butaxamine (INN, also known as butoxamine) is a β2-selective beta blocker.

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Buthalital

Buthalital sodium (INN; Bayinal, Baytinal, Thialbutal, Transithal, Ulbreval), or buthalitone sodium (BAN), is a barbiturate derivative which was under development as a short-acting anesthetic.

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Butidrine

Butidrine (INN) (brand names Betabloc, Butidrate, Recetan), or butedrine or butydrine, also known as hydrobutamine or idrobutamine, is a beta blocker related to pronethalol and propranolol that was developed in the 1960s.

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Butinazocine

Butinazocine (INN) is an opioid analgesic of the benzomorphan family which was never marketed.

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Butorphanol

Butorphanol (BC 2627) is a morphinan-type synthetic agonist–antagonist opioid analgesic developed by Bristol-Myers.

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Butyl cyanoacrylate

n-Butyl cyanoacrylate (n-BCA, NBCA), a cyanoacrylate ester, is a butyl ester of 2-cyano-2-propenoic acid.

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Cabotegravir

Cabotegravir (USAN and INN) (also known as S/GSK1265744 or GSK744) is an investigational new drug under development for the treatment of HIV infection.

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Cafedrine

Cafedrine (INN), also known as norephedrinoethyltheophylline, is a chemical linkage of norephedrine and theophylline and is a cardiac stimulant used to increase blood pressure in people with hypotension.

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Calcifediol

Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalciferol, or 25-hydroxyvitamin D (abbreviated 25(OH)D), is a prehormone that is produced in the liver by hydroxylation of vitamin D3 (cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick.

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Calcipotriol

Calcipotriol (INN) or calcipotriene (USAN) is a synthetic derivative of calcitriol, a form of vitamin D. It is used in the treatment of psoriasis, marketed under the trade name "Dovonex" in the United States, "Daivonex" outside North America, and "Psorcutan" in Germany.

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Calcipotriol/betamethasone dipropionate

Calcipotriol/betamethasone dipropionate (INNs; trade name Daivobet, Enstilar, among others) is a fixed combination of the synthetic vitamin D3 analog calcipotriol (also known as calcipotriene) and the synthetic corticosteroid betamethasone dipropionate for the treatment of plaque psoriasis in adults and adolescents (scalp only).

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Calcitriol

Calcitriol (INN), also called 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D3 and other variants, is the hormonally active metabolite of vitamin D which has three hydroxyl groups.

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Calusterone

Calusterone (INN, USAN) (brand names Methosarb, Riedemil; former developmental code names NSC-88536, U-22550), also known as 7β,17α-dimethyltestosterone, is an orally active anabolic-androgenic steroid (AAS) that is used as an antineoplastic agent.

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Camostat

Camostat (INN) or FOY-305 is a serine protease inhibitor.

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Canakinumab

Canakinumab (INN, trade name Ilaris, previously ACZ885) is a human monoclonal antibody targeted at interleukin-1 beta.

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Candesartan

Candesartan (rINN) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.

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Candocuronium iodide

Candocuronium iodide (INN, formerly chandonium, HS-310) is an aminosteroid neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs.

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Cannabinoid receptor

Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system, which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory.

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Capeserod

Capeserod (INN, previously known as SL65.0155) is a selective 5-HT4 receptor partial agonist with Ki.

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Caplacizumab

Caplacizumab (ALX-0081) (INN) is a bivalent VHH designed for the treatment of thrombotic thrombocytopenic purpura and thrombosis.

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Capromorelin

Capromorelin (INN) (developmental code name CP-424,391) is an investigational medication developed by the Pfizer drug company.

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Capsaicin

Capsaicin ((INN); 8-methyl-N-vanillyl-6-nonenamide) is an active component of chili peppers, which are plants belonging to the genus Capsicum.

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Captodiame

Captodiame (INN), also known as captodiamine, is an antihistamine sold under the trade names Covatine, Covatix, and Suvren which is used as a sedative and anxiolytic.

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Carbaryl

Carbaryl (1-naphthyl methylcarbamate) is a chemical in the carbamate family used chiefly as an insecticide.

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Carbenzide

Carbenzide (INN), also known as carbazic acid, is a hydrazine derivative monoamine oxidase inhibitor (MAOI) antidepressant which was never marketed.

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Carbetocin

Carbetocin (INN, BAN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section.

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Carbocisteine

Carbocisteine (INN), also called carbocysteine (USAN), is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily.

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Carboprost

Carboprost (INN, trade names for the tromethamine salts Hemabate, Tham) is a synthetic prostaglandin analogue of PGF2α (specifically, it is 15-methyl-PGF2α) with oxytocic properties.

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Carbuterol

Carbuterol (INN; carbuterol hydrochloride USAN) is a short-acting β2 adrenoreceptor agonist.

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Carfenazine

Carfenazine (INN) (former developmental code name WY-2445), or carphenazine (BAN), also known as carphenazine maleate (USAN) (brand name Proketazine; former developmental code name NSC-71755), is an antipsychotic and tranquilizer of the phenothiazine group that was withdrawn from the market.

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Carindacillin

Carindacillin (INN), also known as Carbenicillin indanyl (USAN) is a penicillin antibiotic.

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Carmofur

Carmofur (INN) or HCFU (1-hexylcarbamoyl-5-fluorouracil) is a pyrimidine analogue used as an antineoplastic agent.

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Carotuximab

Carotuximab (INN) (TRC-105) is a chimeric monoclonal antibody designed for the treatment of cancer.

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Carpronium chloride

Carpronium chloride (INN) is a hair growth reagent with a vasodilatory action.

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Casokefamide

Casokefamide (INN), also known as β-casomorphin 4027 (β-CM-4027) and -β-casomorphin-5-amide, is a peripherally-specific, synthetic opioid pentapeptide with the amino acid sequence Tyr-D-Ala-Phe-D-Ala-Tyr-NH2.

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Casopitant

Casopitant (INN, tentative trade names Rezonic (U.S.), Zunrisa (Europe)) is an neurokinin 1 receptor (NK1R) antagonist undergoing research for the treatment of chemotherapy-induced nausea and vomiting (CINV).

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Caspofungin

Caspofungin (INN) (brand name Cancidas worldwide) is a lipopeptide antifungal drug from Merck & Co., Inc. discovered by James Balkovec, Regina Black and Frances A. Bouffard.

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Cefacetrile

Cefacetrile (INN, also spelled cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic effective in gram-positive and gram-negative bacterial infections.

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Cefalexin

Cefalexin, also spelled cephalexin, is an antibiotic that can treat a number of bacterial infections.

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Cefaloglycin

Cefaloglycin INN (also spelled cephaloglycin) is a first-generation cephalosporin antibiotic.

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Cefalonium

Cefalonium (INN) is a first-generation cephalosporin antibiotic.

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Cefalotin

Cefalotin (INN) or cephalothin (USAN) is a first-generation cephalosporin antibiotic.

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Cefamandole

Cefamandole (INN, also known as cephamandole) is a second-generation broad-spectrum cephalosporin antibiotic.

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Cefapirin

Cefapirin (INN, also spelled cephapirin) is an injectable, first-generation cephalosporin antibiotic.

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Cefazaflur

Cefazaflur (INN) is a first-generation cephalosporin antibiotic.

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Cefbuperazone

Cefbuperazone (INN) is a second-generation cephalosporin antibiotic.

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Cefcapene

Cefcapene (INN) is a third-generation cephalosporin antibiotic.

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Cefdaloxime

Cefdaloxime (INN) is a third-generation cephalosporin antibiotic.

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Cefmatilen

Cefmatilen (INN, codenamed S-1090) is an orally-active cephalosporin antibiotic.

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Cefminox

Cefminox (INN) is a second-generation cephalosporin antibiotic.

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Cefovecin

Cefovecin (INN) is an antibiotic of the cephalosporin class, licensed for the treatment of skin infections in cats and dogs.

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Cefozopran

Cefozopran (INN) is a fourth-generation cephalosporin.

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Cefpimizole

Cefpimizole (INN) is a third-generation cephalosporin antibiotic.

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Cefradine

Cefradine (INN) (formerly cephradine BAN) is a first generation cephalosporin antibiotic.

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Cefroxadine

Cefroxadine (INN, trade names Oraspor and Cefthan-DS) is a cephalosporin antibiotic.

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Ceftaroline fosamil

Ceftaroline fosamil (INN), brand name Teflaro in the US and Zinforo in Europe, is a fifth-generation cephalosporin antibiotic.

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Cefteram

Cefteram (INN) is a third-generation cephalosporin antibiotic.

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Ceftiolene

Ceftiolene (INN) is a third-generation cephalosporin antibiotic.

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Cefuzonam

Cefuzonam (INN) is a second-generation cephalosporin antibiotic.

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Cenicriviroc

Cenicriviroc (INN, code names TAK-652, TBR-652) is an experimental drug candidate for the treatment of HIV infection.

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Centanafadine

Centanafadine (INN) (former developmental code name EB-1020) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) that began its development with Euthymics Bioscience after they acquired DOV Pharmaceutical.

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Cephalosporin

The cephalosporins (sg.) are a class of β-lactam antibiotics originally derived from the fungus Acremonium, which was previously known as "Cephalosporium".

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Cericlamine

Cericlamine (INN) (developmental code name JO-1017) is a potent and moderately selective serotonin reuptake inhibitor (SSRI) of the amphetamine family (specifically, a derivative of phentermine, and closely related to chlorphentermine, a highly selective serotonin releasing agent) that was investigated as an antidepressant for the treatment of depression, anxiety disorders, and anorexia nervosa by Jouveinal but did not complete development and was never marketed.

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Ceritinib

Ceritinib (INN, trade name Zykadia) is a prescription-only drug used for the treatment non-small cell lung cancer (NSCLC).

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Cerivastatin

Cerivastatin (INN, brand names: Baycol, Lipobay) is a synthetic member of the class of statins used to lower cholesterol and prevent cardiovascular disease.

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Ceronapril

Ceronapril (INN, proposed trade names Ceranapril, Novopril) in a phosphonate ACE inhibitor that was never marketed.

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Ceruletide

Ceruletide (INN), also known as cerulein or caerulein, is a ten amino acid oligopeptide that stimulates smooth muscle and increases digestive secretions.

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Cetraxate

Cetraxate (INN) is an oral gastrointestinal medication which has a cytoprotective effect.

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Chemotherapy

Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.

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Chloral betaine

Chloral betaine (USAN, BAN) (brand names Beta-Chlor, Somilan), also known as cloral betaine (INN), is a sedative-hypnotic drug.

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Chlormethine

No description.

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Chlormidazole

Chlormidazole (INN, also known as clomidazole) is used as a spasmolytic and azole antifungal drug.

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Chlortalidone

Chlortalidone (INN/BAN) or chlorthalidone (USAN) is a diuretic medication used to treat hypertension (high blood pressure), originally marketed as Hygroton in the USA.

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Chlorzoxazone

Chlorzoxazone (INN) is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes. It is sold under the trade names "'Lorzone'", Paraflex and Muscol and in combination form as Parafon Forte, a combination of chlorzoxazone and acetaminophen (paracetamol). Possible side effects include dizziness, lightheadedness, malaise, nausea, vomiting, and liver dysfunction. Used with acetaminophen it has added risk of hepatoxicity, which is why the combination is not recommended. It can also be administered for acute pain in general and for tension headache (muscle contraction headache). Like metaxalone, no specific mechanism of action has been identified for chlorzoxazone, with general central nervous system depression being the only currently accepted aspect to its medical benefits. Search for the exact mechanism of action is ongoing but limited due to the existence of more-effective safe muscle relaxers (ex. diazepam, cyclobenzaprine, tizanidine) greatly limiting the potential benefit of identifying novel compounds which share chlozoxazone's mechanism of action. As of 2015 the cost for a typical course of medication in the United States is less than 25 USD.

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Cholecalciferol

Cholecalciferol, also known as vitamin D3 and colecalciferol, is a type of vitamin D which is made by the skin, found in some foods, and taken as a dietary supplement.

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Choline theophyllinate

Choline theophyllinate (INN), also known as oxtriphylline, is a cough medicine derived from xanthine that acts as a bronchodilator to open up airways in the lung.

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Cianopramine

Cianopramine (INN) (developmental code name Ro 11-2465), also known as 3-cyanoimipramine, is a tricyclic antidepressant related to imipramine that acts as a serotonin reuptake inhibitor and weak serotonin receptor antagonist.

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Ciclacillin

Ciclacillin (INN) or cyclacillin (USAN), trade names Cyclapen, Cyclapen-W, Vastcillin, and others, is an aminopenicillin antibiotic.

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Ciclafrine

Ciclafrine (INN) is a sympathomimetic phenethylamine and antihypertensive which does not appear to have ever been marketed.

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Ciclindole

Ciclindole (INN; WIN-27,147-2), also known as cyclindole (USAN), is an antipsychotic with a tricyclic structure that was never marketed.

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Ciclosporin

Ciclosporin, also spelled cyclosporine and cyclosporin, is an immunosuppressant medication and natural product.

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Ciglitazone

Ciglitazone (INN) is a thiazolidinedione.

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Cilnidipine

Cilnidipine (INN) is a calcium channel blocker.

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Cilofungin

Cilofungin (INN) is the first clinically applied member of the echinocandin family of antifungal drugs.

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Cilomilast

Cilomilast (INN, codenamed SB-207,499, proposed trade name Ariflo) is a drug which was developed for the treatment of respiratory disorders such as asthma and chronic obstructive pulmonary disease (COPD).

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Cimaterol

Cimaterol (INN) is a beta-adrenergic agonist.

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Cimemoxin

Cimemoxin (INN), or cyclohexylmethylhydrazine, is a hydrazine monoamine oxidase inhibitor (MAOI) antidepressant which was never marketed.

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Cinacalcet

Cinacalcet (INN) is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues (Van Wagenen et al. (2001), U.S. Pat. 6,211,244).

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Cinanserin

Cinanserin (INN) is a 5-HT2A and 5-HT2C receptor antagonist which was discovered in the 1960s.

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Cinchocaine

Cinchocaine (INN/BAN) or dibucaine (USAN) is an amide local anesthetic.

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Cingestol

Cingestol (INN, USAN) (former tentative brand name Lutisan), also known as 17α-ethynylestr-5-en-17β-ol, is a steroidal progestin of the 19-nortestosterone group that was never marketed.

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Cinnamedrine

Cinnamedrine (INN, USAN), also known as N-cinnamylephedrine, is a sympathomimetic drug with similar effects relative to those of ephedrine.

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Cipemastat

Cipemastat (rINN, also known as Ro 32-3555 and by the tentative trade name Trocade) is a selective inhibitor of matrix metalloproteinase-1 that has been investigated as an anti-arthritis agent.

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Ciraparantag

No description.

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Cisatracurium besilate

Cisatracurium besilate (INN; cisatracurium besylate (USAN); formerly recognized as 51W89; trade name Nimbex) is a bisbenzyltetrahydroisoquinolinium that has effect as a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

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Cismadinone

Cismadinone (INN), also known as 6α-chloro-17α-hydroxypregna-1,4-diene-3,20-dione or 6α-chloro-δ1-dehydro-17α-hydroxyprogesterone, is a steroidal progestin closely related to the 17α-hydroxyprogesterone derivatives that was never marketed.

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Citicoline

Citicoline (INN), also known as cytidine diphosphate-choline (CDP-Choline) or cytidine 5'-diphosphocholine is an intermediate in the generation of phosphatidylcholine from choline, a common biochemical process in cell membranes.

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Clamoxyquine

Clamoxyquine (INN) or clamoxyquin (former BAN), as the pamoate or hydrochloride salt, is an antiamebic and antidiarrheal drug.

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Clenoliximab

Clenoliximab (INN) is a monoclonal antibody against CD4.

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Clevidipine

Clevidipine (INN, trade name Cleviprex) is a dihydropyridine calcium channel blocker indicated for the reduction of blood pressure when oral therapy is not feasible or not desirable.

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Clevudine

Clevudine (INN) is an antiviral drug for the treatment of hepatitis B (HBV).

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Clidinium bromide

Clidinium bromide (INN) is an anticholinergic (specifically a muscarinic antagonist) drug.

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Clinofibrate

Clinofibrate (INN) (trade name Lipoclin) is a fibrate.

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Clobetasone

Clobetasone (INN) is a corticosteroid used in dermatology, for treating such skin inflammation as seen in eczema, psoriasis and other forms of dermatitis, and ophthalmology.

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Clodronic acid

Clodronic acid (INN) or clodronate disodium (USAN) is a first generation (non-nitrogenous) bisphosphonate.

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Clofedanol

Clofedanol (INN) or chlophedianol (BAN) is a centrally acting cough suppressant used in the treatment of dry cough.

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Clogestone

Clogestone (INN, BAN), also known as chlormadinol or as 3β,17α-dihydroxy-6-chloropregna-4,6-diene-20-one, is a steroidal progestin that was synthesized in 1964 and was investigated as a progestin-only contraceptive but was never marketed.

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Clomegestone

Clomegestone (INN), or clomagestone, also known as 6-chloro-17α-hydroxy-16α-methylpregna-4,6-diene-3,20-dione, is a steroidal progestin of the 17α-hydroxyprogesterone group that was never marketed.

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Clomifenoxide

Clomifenoxide (INN), also known as clomifene N-oxide, is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that is described as an antiestrogen and "gonad stimulant" and was never marketed.

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Cloperastine

Cloperastine (INN) or cloperastin, also known as cloperastine hydrochloride (JAN) (brand names Hustazol, Nitossil, Seki) and cloperastine fendizoate (or hybenzoate), is an antitussive and antihistamine that is marketed as a cough suppressant in Japan, Hong Kong, and in some European countries.

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Clorgiline

Clorgiline (INN), or clorgyline (BAN), is a monoamine oxidase inhibitor (MAOI) structurally related to pargyline which is described as an antidepressant.

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Clovoxamine

Clovoxamine (INN) (developmental code name DU-23811) is a drug that was discovered in the 1970s and was subsequently investigated as an antidepressant and anxiolytic agent but was never marketed.

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Cofetuzumab pelidotin

Cofetuzumab pelidotin (PF-06647020) (INN) is a humanized monoclonal antibody designed for the treatment of cancer.

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Cogazocine

Cogazocine (INN) is an opioid analgesic of the benzomorphan family which was never marketed.

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Colestilan

Colestilan (INN, trade name BindRen) is a medication that acts as a phosphate binder and bile acid sequestrant.

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Colestyramine

Colestyramine (INN) or cholestyramine (USAN) (trade names Questran, Questran Light, Cholybar, Olestyr) is a bile acid sequestrant, which binds bile in the gastrointestinal tract to prevent its reabsorption.

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Colextran

Colextran (INN) is a bile acid sequestrant.

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Colforsin

Colforsin (INN) is a water-soluble derivative of forskolin.

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Coluracetam

Coluracetam (INN) (code name BCI-540; formerly MKC-231) is a nootropic agent of the racetam family.

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Compendium of Pharmaceuticals and Specialties

The Compendium of Pharmaceuticals and Specialties: The Canadian Drug Reference for Health Professionals, more commonly known by its abbreviation CPS,Repchinsky C. The CPS: Love, hate and expectations.

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Conorfone

Conorfone (INN; TR-5109), also known as conorphone and codorphone, as well as conorphone hydrochloride (USAN), is an opioid analgesic that was never marketed.

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Controlled Substances Act

The Controlled Substances Act (CSA) is the statute establishing federal U.S. drug policy under which the manufacture, importation, possession, use, and distribution of certain substances is regulated.

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Corbadrine

Corbadrine (INN; marketed as Neo-Cobefrine), also known as levonordefrin (USAN) and α-methylnorepinephrine, is a catecholamine sympathomimetic used as a topical nasal decongestant and vasoconstrictor in dentistry in the United States, (usually in a pre-mixed solution with local anesthetics, such as mepivacaine).

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Corticorelin

Corticorelin (INN) is a diagnostic agent.

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Corticotropin-releasing hormone

Corticotropin-releasing hormone (CRH) (also known as corticotropin-releasing factor (CRF) or corticoliberin; corticotropin may also be spelled corticotrophin) is a peptide hormone involved in the stress response.

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Crocetin

Crocetin is a natural apocarotenoid dicarboxylic acid that is found in the crocus flower and Gardenia jasminoides (fruits).

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Croconazole

Croconazole (INN) is an imidazole antifungal.

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Cromakalim

Cromakalim (INN) is a potassium channel-opening vasodilator.

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Cromoglicic acid

Cromoglicic acid (INN) (also referred to as cromolyn (USAN), cromoglycate (former BAN), or cromoglicate) is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium.

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Crotedumab

Crotedumab (REGN1193) (INN) is a humanized monoclonal antibody designed for the treatment of diabetes.

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Cyclarbamate

Cyclarbamate (INN; Casmalon), also known as cyclopentaphene, is a muscle relaxant and tranquilizer of the carbamate family which has been marketed by Cassenne in France since 1961.

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Cyclopregnol

Cyclopregnol (INN), also known as neurosterone, as well as 6β-hydroxy-3:5-cyclopregnan-20-one, is a synthetic pregnane steroid which was developed in the 1950s as a "psychotropic agent" for the treatment of mental disorders but was never marketed.

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Cypenamine

Cypenamine (INN, BAN), or cypenamine hydrochloride (USAN), also known as 2-phenylcyclopentylamine, is a psychostimulant drug which was developed by a group at the William S. Merrell Chemical Company in the 1940s.

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Dacemazine

Dacemazine (INN, also known as Ahistan and Histantine) Retrieved on August 2, 2008 through Google Book Search.

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Dacuronium bromide

Dacuronium bromide (INN, BAN) (developmental code name NB-68) is an aminosteroid neuromuscular blocking agent which was never marketed.

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Dalbavancin

Dalbavancin (INN, trade names Dalvance in the US and Xydalba in Europe) is a novel second-generation lipoglycopeptide antibiotic.

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Danoprevir

Danoprevir (INN) (by Array BioPharma) is an orally available 15-membered macrocyclic peptidomimetic inhibitor of NS3/4A HCV protease.

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Dantron

Dantron (INN), also known as chrysazin or 1,8-dihydroxyanthraquinone, is an organic substance, formally derived from anthraquinone by the replacement of two hydrogen atoms by hydroxyl groups (–OH).

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Dapagliflozin

Dapagliflozin (INN, USAN, trade name Farxiga in the U.S. and Forxiga in the EU and Russia) is a drug of the gliflozin class, used to treat type 2 diabetes.

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Darbepoetin alfa

Darbepoetin alfa (INN) is a re-engineered form of erythropoietin containing 5 amino acid changes (N30, T32, V87, N88, T90) resulting in the creation of 2 new sites for N-linked carbohydrate addition.

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Dasolampanel

Dasolampanel (INN, USAN, code name NGX-426) is an orally bioavailable analog of tezampanel and thereby competitive antagonist of the AMPA and kainate receptors which was under development by Raptor Pharmaceuticals/Torrey Pines Therapeutics for the treatment of chronic pain conditions including neuropathic pain and migraine.

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Dasotraline

Dasotraline (INN) (former developmental code name SEP-225,289) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) that is under development by Sunovion for clinical use.

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Dénomination Commune Française

The Dénomination Commune Française (DCF), or "Common French Denomination/Name" in English, is the formal French name for a drug.

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Decoglurant

Decoglurant (INN) (code name RG1578, RO4995819) is a negative allosteric modulator of the mGlu2 and mGlu3 receptors which was under development by Roche for the adjunctive treatment of major depressive disorder.

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Dectaflur

Dectaflur (INN) is a fluoride-containing substance used for the prevention and treatment of dental caries, sensitive teeth, and the refluoridation of damaged tooth enamel, typically in combination with olaflur.

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Delafloxacin

Delafloxacin (INN) (trade name Baxdela) is a fluoroquinolone antibiotic used to treat acute bacterial skin and skin structure infections.

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Delmadinone

Delmadinone (INN) is a steroidal progestin which was never marketed.

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Demeclocycline

Demeclocycline (INN, BAN, USAN) (brand names Declomycin, Declostatin, Ledermycin, Bioterciclin, Deganol, Deteclo), also known under the brand names Detravis, Meciclin, Mexocine, Clortetrin, is a semisynthetic tetracycline antibiotic which was derived from a strain of Streptomyces aureofaciens.

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Demecolcine

Demecolcine (INN; also known as colcemid) is a drug used in chemotherapy.

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Demoxytocin

Demoxytocin (INN) (brand names Sandopart, Odeax, Sandopral), also known as desaminooxytocin or deaminooxytocin, as well as 1-(3-mercaptopropanoic acid)oxytocin (OT), is an oxytocic peptide drug that is used to induce labor, promote lactation, and to prevent and treat puerperal (postpartum) mastitis (breast inflammation).

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Denintuzumab mafodotin

Denintuzumab mafodotin (SGN-19A) (INN) is a humanized monoclonal antibody designed for the treatment of B-cell malignancies.

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Denominazione Comune Italiana

The Denominazione Comune Italiana (DCIT), or "Common Italian Denomination/Name" in English, is the formal Italian generic name for a drug.

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Denopamine

Denopamine (INN) is a cardiotonic drug which acts as a β1 adrenergic receptor agonist.

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Denufosol

Denufosol (INN) is an inhaled drug for the treatment of cystic fibrosis, being developed by Inspire Pharmaceuticals and sponsored by the Cystic Fibrosis Foundation.

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Depatuxizumab mafodotin

Depatuxizumab mafodotin (ABT-414) (INN) is an antibody-drug conjugate designed for the treatment of cancer.

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Depramine

Depramine (INN; GP-31,406), also known as balipramine (BAN) and as 10,11-dehydroimipramine, is a tricyclic antidepressant (TCA) which was never marketed.

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Deserpidine

Deserpidine (INN) is an antihypertensive drug related to reserpine which occurs naturally in Rauvolfia spp.

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Desfesoterodine

Desfesoterodine (INN, also called 5-hydroxymethyltolterodine) is an antimuscarinic drug.

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Desmethylmoramide

Desmethylmoramide (INN) is an opioid analgesic related to dextromoramide (the active (+)-isomer of moramide) that was synthesized and characterized in the late 1950s but was never marketed.

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Desonide

Desonide (INN) is a low-potency topical corticosteroid anti-inflammatory that has been available since the 1970s.

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Dextroamphetamine

Dextroamphetamine is a potent central nervous system (CNS) stimulant and amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.

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Dezocine

Dezocine (INN, USAN) (brand name Dalgan) is a marketed opioid analgesic of the benzomorphan group.

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Diacerein

Diacerein (INN), also known as diacetylrhein, is a slow-acting medicine of the class anthraquinone used to treat joint diseases such as osteoarthritis (swelling and pain in the joints).

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Diazinon

Diazinon (IUPAC name: O,O-Diethyl O- phosphorothioate, INN - Dimpylate), a colorless to dark brown liquid, is a thiophosphoric acid ester developed in 1952 by Ciba-Geigy, a Swiss chemical company (later Novartis and then Syngenta).

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Diazoxide

Diazoxide (INN; brand name Proglycem) is a potassium channel activator, which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions.

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Dicirenone

Dicirenone (INN, USAN; developmental code name SC-26304; also known as 7α-carboxyisopropylspirolactone) is a synthetic, steroidal antimineralocorticoid of the spirolactone group which was developed as a diuretic and antihypertensive agent but was never marketed.

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Dicoumarol

Dicoumarol (INN) or dicumarol (USAN) is a naturally occurring anticoagulant that functions as a functional vitamin K depleter (similar to warfarin, a drug that dicoumarol inspired).

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Difebarbamate

Difebarbamate (INN) is a tranquilizer of the barbiturate and carbamate families which is used in Europe as a component of a combination drug formulation referred to as tetrabamate (Atrium, Sevrium).

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Difelikefalin

Difelikefalin (INN) (developmental code names CR845, FE-202845), also known as D-Phe-D-Phe-D-Leu-D-Lys- (as the acetate salt), is an analgesic opioid peptide acting as a peripherally specific, highly selective agonist of the κ-opioid receptor (KOR).

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Difemetorex

Difemetorex (INN; sold as Cleofil), also known as diphemethoxidine, is a stimulant drug of the piperidine class which was used as an appetite suppressant, but produced intolerable side effects such as insomnia which limited its clinical use.

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Difenamizole

Difenamizole (INN) (brand name Pasalin; former developmental code name AP-14) is a nonsteroidal anti-inflammatory drug (NSAID) and analgesic of the pyrazolone group related to metamizole.

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Difloxacin

Difloxacin (INN), marketed under the trade name Dicural, is a second-generation, synthetic fluoroquinolone antibiotic used in veterinary medicine.

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Diflucortolone

Diflucortolone (INN), or difluocortolone, is a corticosteroid.

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Diiodohydroxyquinoline

The quinoline derivative diiodohydroxyquinoline (INN) or iodoquinol (USAN), can be used in the treatment of amoebiasis.

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Diltiazem

Diltiazem (INN) is a nondihydropyridine (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia.

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Dimemorfan

Dimemorfan (INN) (or dimemorphan) (brand names Astomin, Dastosirr, Tusben), or dimemorfan phosphate (JAN), also known as 3,17-dimethylmorphinan, is an antitussive (cough suppressant) of the morphinan family that is widely used in Japan and is also marketed in Spain and Italy.

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Dimenoxadol

Dimenoxadol (INN) (brand name Estocin (in Russia)), or dimenoxadole (BAN), is an opioid analgesic which is a benzilic acid derivative, closely related to benactyzine (an anticholinergic).

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Dimepheptanol

Dimepheptanol (INN; Amidol, Pangerin), also known as methadol or racemethadol, is a synthetic opioid analgesic related to methadone.

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Dimepregnen

Dimepregnen (INN, BAN) (developmental code name ST-1411), or 6α,16α-dimethylpregn-4-en-3β-ol-20-one, is a pregnene steroid described as an antiestrogen that was synthesized in 1968 and was never marketed.

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Dimethylaminoisopropanol

Dimethylaminoisopropanol is a chemical compound with the molecular formula C5H13NO that is classified as an amino alcohol.

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Dimethylamphetamine

Dimethylamphetamine (Metrotonin), also known as dimetamfetamine (INN), dimephenopan and N,N-dimethylamphetamine, is a stimulant drug of the phenethylamine and amphetamine chemical classes.

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Dimethyltubocurarinium chloride

Dimethyltubocurarinium chloride (INN), or metocurine chloride (USAN), also known as dimethyltubocurarine chloride, is a non-depolarizing nicotinic acetylcholine receptor antagonist used as a muscle relaxant.

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Dimetotiazine

Dimetotiazine (INN) is a phenothiazine drug used for the treatment of migraine.

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Diminazene

Diminazene (INN; also known as diminazen) is an anti-infective medication for animals that is sold under a variety of brand names.

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Dioxaphetyl butyrate

Dioxaphetyl butyrate (INN; trade names Amidalgon, Spasmoxal) is an opioid analgesic which is a diphenylacetic acid derivative, related to other open-chain opioid drugs such as dextropropoxyphene, levacetylmethadol (LAAM), lefetamine and dimenoxadol.

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Dipivefrine

Dipivefrine (INN) or dipivefrin (USAN), trade name Propine among others, is a prodrug of epinephrine, and is used to treat open-angle glaucoma.

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Dipraglurant

Dipraglurant (INN) (code name ADX-48621) is a negative allosteric modulator of the mGlu5 receptor which is under development by Addex Therapeutics for the treatment of Parkinson's disease levodopa-induced dyskinesia (PD-LID).

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Diprophylline

Diprophylline (INN) or dyphylline (USAN) (trade names Dilor, Lufyllin), is a xanthine derivative with bronchodilator and vasodilator effects.

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Diridavumab

Diridavumab (CR6261) (INN) is a monoclonal antibody designed for the treatment of influenza A. This drug was developed by Janssen Pharmaceutical Companies of Johnson & Johnson.

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Disopyramide

Disopyramide (INN, trade names Norpace and Rythmodan) is an antiarrhythmic medication used in the treatment of ventricular tachycardia.

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Dithranol

Dithranol (INN) or anthralin (USAN and former BAN) is a Hydroxyanthrone, anthracene derivative, medicine applied to the skin of people with psoriasis.

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Dizocilpine

Dizocilpine (INN), also known as MK-801, is a noncompetitive antagonist of the ''N''-Methyl-D-aspartate (NMDA) receptor, a glutamate receptor, discovered by a team at Merck in 1982.

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Docosahexaenoic acid

Docosahexaenoic acid (DHA) is an omega-3 fatty acid that is a primary structural component of the human brain, cerebral cortex, skin, and retina.

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Domagrozumab

Domagrozumab (PF-06252616) (INN) is a humanized monoclonal antibody designed for the treatment of Duchenne muscular dystrophy.

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Domoxin

Domoxin (INN) is a hydrazine derivative monoamine oxidase inhibitor (MAOI) antidepressant which was never marketed.

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Donitriptan

Donitriptan (INN) (code name F-11356) is a triptan drug which was investigated as an antimigraine agent but ultimately was never marketed.

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DOTA (chelator)

DOTA (also known as tetraxetan) is an organic compound with the formula (CH2CH2NCH2CO2H)4.

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Drinabant

Drinabant (INN; AVE-1625) is a drug that acts as a selective CB1 receptor antagonist, which was under investigation varyingly by Sanofi-Aventis as a treatment for obesity, schizophrenia, Alzheimer's disease, Parkinson's disease, and nicotine dependence.

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Droloxifene

Droloxifene (INN, USAN) (former developmental code names FK-435, ICI-79280, K-060, K-21060E, RP-60850), also known as 3-hydroxytamoxifen, is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that was developed originally in Germany and later in Japan for the treatment of breast cancer, osteoporosis in men and postmenopausal women, and cardiovascular disorders but was abandoned and never marketed.

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Dronabinol

Dronabinol – trade names Marinol and Syndros – is a synthetic form of tetrahydrocannabinol (THC) approved by the FDA as an appetite stimulant for people with AIDS and antiemetic for people receiving chemotherapy.

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Drotaverine

Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, used to enhance cervical dilation during childbirth.

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Droxidopa

Droxidopa (INN; trade name Northera; also known as L-DOPS, L-threo-dihydroxyphenylserine, L-threo-DOPS and SM-5688) is a synthetic amino acid precursor which acts as a prodrug to the neurotransmitter norepinephrine (noradrenaline).

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Drug nomenclature

Drug nomenclature is the systematic naming of drugs, especially pharmaceutical drugs.

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Drug policy of India

The major drug laws of India are the Narcotic Drugs and Psychotropic Substances Act (1985) and the Prevention of Illicit Trafficking in Narcotic Drugs and Psychotropic Substances Act (1985).

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Duligotuzumab

Duligotuzumab (INN) is a humanized IgG1 monoclonal antibody designed for the treatment of cancer.

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Duvelisib

Duvelisib (INN, previously known as IPI-145) is a dual inhibitor of PI3Kδ and PI3Kγ, in development as a treatment for hematologic malignancies as well as a broad range of inflammatory conditions.

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Duvortuxizumab

Duvortuxizumab (INN) is a chimeric/humanized monoclonal antibody designed for the treatment of B-cell malignancies.

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Edivoxetine

Edivoxetine (INN; code name LY-2216684) is a drug which acts as a selective norepinephrine reuptake inhibitor and was under development by Eli Lilly for attention-deficit disorder (ADD) and as an antidepressant treatment.

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Efaproxiral

Efaproxiral (INN) is an analogue of the cholesterol drug bezafibrate developed for the treatment of depression, traumatic brain injury, ischemia, stroke, myocardial infarction, diabetes, hypoxia, sickle cell disease, hypercholesterolemia and as a radio sensitiser.

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Efonidipine

Efonidipine (INN) is a dihydropyridine calcium channel blocker marketed by Shionogi & Co.

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EGTA (chemical)

EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N',N'-tetraacetic acid), also known as egtazic acid (INN, USAN), is an aminopolycarboxylic acid, a chelating agent.

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Elacestrant

Elacestrant (INN) (developmental code names RAD-1901, ER-306323) is a nonsteroidal combined selective estrogen receptor modulator (SERM) and selective estrogen receptor degrader (SERD) (described as a "SERM/SERD hybrid (SSH)") that was discovered by Eisai and is under development by Radius Health and Takeda for the treatment of menopausal vasomotor symptoms (hot flashes) and estrogen receptor (ER)-positive advanced breast cancer, as well as endometrial cancer and kidney cancer.

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Elafibranor

Elafibranor (INN, code name GFT505) is an experimental medication that is being studied and developed by Genfit for the treatment of cardiometabolic diseases including diabetes, insulin resistance, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD).

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Elesclomol

Elesclomol (INN, codenamed STA-4783) is a drug that triggers apoptosis (programmed cell death) in cancer cells.

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Elezanumab

Elezanumab (ABT-555, PR-1432051) (INN) is a human monoclonal antibody designed for the treatment of spinal cord injury and multiple sclerosis.

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Eliglustat

Eliglustat (INN, USAN; trade name Cerdelga) is a treatment for Gaucher's disease developed by Genzyme Corp that was approved by the FDA August 2014.

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Elinogrel

Elinogrel (INN, USAN) was an experimental antiplatelet drug acting as a P2Y12 inhibitor.

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Eltrombopag

Eltrombopag (rINN, codenamed SB-497115-GR) is a medication that has been developed for certain conditions that lead to thrombocytopenia (abnormally low platelet counts). It is a small molecule agonist of the c-mpl (TpoR) receptor, which is the physiological target of the hormone thrombopoietin. Eltrombopag was discovered as a result of research collaboration between GlaxoSmithKline and Ligand Pharmaceuticals. Designated an orphan drug in the United States and European Union, it is being manufactured and marketed by GlaxoSmithKline under the trade name Promacta in the USA and is marketed as Revolade in the EU.

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Emactuzumab

Emactuzumab (INN) (RG-7155) is a humanized monoclonal antibody designed for the treatment of cancer.

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Embutramide

Embutramide (INN, USAN, BAN) (brand name Embutane) is a potent opioid analgesic and sedative drug that is structurally related to methadone.

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Emibetuzumab

Emibetuzumab (INN) (LY2875358) is a humanized monoclonal antibody designed for the treatment of cancer.

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Enantiopure drug

An enantiopure drug is a pharmaceutical that is available in one specific enantiomeric form.

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Enasidenib

Enasidenib (INN; trade name Idhifa) is a drug used to treat relapsed or refractory acute myeloid leukemia in people with specific mutations of the isocitrate dehydrogenase 2 (IDH2) gene, determined by an FDA-approved IDH2 companion diagnostic test.

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Encenicline

Encenicline (INN, USAN, code names EVP-6124, MT-4666) is a selective partial agonist of the α7 nicotinic receptor, and is in phase III clinical trials for the treatment of cognitive impairment in schizophrenia.

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Enciprazine

Enciprazine (INN, BAN; enciprazine hydrochloride (USAN); developmental code names WY-48624, D-3112), is an anxiolytic and antipsychotic of the phenylpiperazine class which was never marketed.

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Endrisone

Endrisone (INN) (brand name Aldrisone), or endrysone (USAN), is a synthetic, steroidal glucocorticoid which is or has been marketed in Italy by.

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Enfuvirtide

Enfuvirtide (INN) is an HIV fusion inhibitor, the first of a novel class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.

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Enocitabine

Enocitabine (INN, marketed under the brand name Sunrabin) is a nucleoside analog used as chemotherapy.

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Enoticumab

Enoticumab (INN) is a human monoclonal antibody that binds to DLL4.

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Enoximone

Enoximone (INN, trade name Perfan) is an imidazole phosphodiesterase inhibitor.

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Enoxolone

Enoxolone (INN, BAN; also known as glycyrrhetinic acid or glycyrrhetic acid) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.

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Enpiprazole

Enpiprazole (INN, BAN) is an anxiolytic drug of the phenylpiperazine group that was never marketed.

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Ensulizole

Ensulizole (INN; also known as phenylbenzimidazole sulfonic acid) is a common sunscreen agent.

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Entrectinib

Entrectinib (INN, previously known as RXDX-101 and NMS-E628) is an investigational drug with preliminary antitumor activity.

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Enviomycin

Enviomycin (INN, also called tuberactinomycin N) is an antibiotic drug, isolated from Streptomyces griseoverticillatus var.

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Enzacamene

Enzacamene (INN; also known as 4-methylbenzylidene camphor or 4-MBC) is an organic camphor derivative that is used in the cosmetic industry for its ability to protect the skin against UV, specifically UV B radiation.

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Epelsiban

Epelsiban (INN, USAN, code name GSK-557,296-B) is an orally bioavailable drug which acts as oxytocin receptor antagonist.

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Epirizole

Epirizole (INN) is a nonsteroidal anti-inflammatory drug.

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Epoetin alfa

Epoetin alfa (rINN) is a human erythropoietin produced in cell culture using recombinant DNA technology.

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Epoetin beta

Epoetin beta (rINN) is a synthetic, recombinant form of erythropoietin, a protein that promotes the production of red blood cells.

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Epostane

Epostane (INN, USAN, BAN) (developmental code name WIN-32729) is an inhibitor of 3β-hydroxysteroid dehydrogenase (3β-HSD) that was developed as an contraceptive, abortifacient, and oxytocic drug but was never marketed.

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Eprobemide

Eprobemide (INN) is a pharmaceutical drug that was used as an antidepressant in Russia (under the brand name Бефол/Befol).

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Ergoline

Ergoline derivatives comprise a diverse group of chemical compounds whose structural skeleton is the alkaloid ergoline.

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Ertugliflozin

Ertugliflozin (INN; trade name Steglatro) is a drug for the treatment of type 2 diabetes.

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Erythritol tetranitrate

Erythritol tetranitrate (ETN) is an explosive compound chemically similar to PETN.

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Esaxerenone

Esaxerenone (INN) (developmental code names CS-3150, XL-550) is a nonsteroidal antimineralocorticoid which was discovered by Exelixis and is now under development by Daiichi Sankyo Company for the treatment of hypertension, essential hypertension, hyperaldosteronism, and diabetic nephropathies.

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Estradiol hexahydrobenzoate

Estradiol hexahydrobenzoate (INN) (brand names Benzo-Ginoestril A.P., BenzoGynoestryl Retard, Ginestryl-15-Depot, Menodin, Tardoginestryl), also known as 17-hexahydrobenzoylestradiol or estradiol 17-cyclohexanecarboxylate, is a semisynthetic, steroidal estrogen.

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Estramustine phosphate

Estramustine phosphate (EMP), sold under the brand names Emcyt and Estracyt, is a medication which is used in the treatment of prostate cancer in men.

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Estrazinol

Estrazinol (INN), or as estrazinol hydrobromide (USAN) (developmental code name W-4454A), also known as 3-methoxy-8-aza-19-norpregna-1,3,5(10)-trien-20-yn-17-ol, is a synthetic, steroidal estrogen that was synthesized in 1968 and further characterized in 1973 but was never marketed.

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Estrofurate

Estrofurate (INN, USAN) (developmental code name AY-11483), also known as 17α-(3-furyl)-estra-1,3,5(10),7-tetraene-3,17-diol 3-acetate, is a synthetic, steroidal estrogen that was synthesized in 1967 and studied in the late 1960s and early 1970s but was never marketed.

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Etabonate

Etabonate is the name for ethyl carbonate esters in International nonproprietary names (INNs) and United States Adopted Names (USANs) for pharmaceutical substances.

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Etacrynic acid

Etacrynic acid (INN) or ethacrynic acid (USAN), trade name Edecrin, is a loop diuretic used to treat high blood pressure and the swelling caused by diseases like congestive heart failure, liver failure, and kidney failure.

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Etafedrine

Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has the brand name Nethaprin.

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Etamestrol

Etamestrol (INN) (developmental code name ZK-77992), or eptamestrol, also known as 7α-methyl-19-nor-17α-pregna-1,3,5(10)-trien-20-yne-1,3,17-triol 1,3-dibenzoate, is a synthetic, steroidal estrogen described as an ovulation inhibitor (or hormonal contraceptive) that was synthesized in 1979 but was never marketed.

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Etamiphylline

Etamiphylline or etamiphyllin (INN) is a xanthine intended for use as an anti-asthma agent.

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Etamivan

Etamivan (INN, or ethamivan (USAN); trade names Analepticon and Vandid) is a respiratory stimulant drug related to nikethamide.

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Etazepine

Etazepine (INN) is an anticonvulsant with a tricyclic structure which is related to the benzodiazepines, but was never marketed.

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Ethylenediaminetetraacetic acid

Ethylenediaminetetraacetic acid (EDTA), also known by several other names, is a chemical originating in multiseasonal plants with dormancy stages as a lipidopreservative which helps to develop the stem, currently used for both industrial and medical purposes.

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Ethynerone

Ethynerone (INN, USAN), also known as 17α-(2-chloroethynyl)estra-4,9-dien-17β-ol-3-one, is a steroidal progestin of the 19-nortestosterone group that was first reported in 1961 but was never marketed.

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Etidronic acid

Etidronic acid (INN) or 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP) is a bisphosphonate used in detergents, water treatment, cosmetics and pharmaceutical treatment.

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Etifelmine

Etifelmine (INN; also known as gilutensin) is a stimulant drug.

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Etifoxine

Etifoxine (INN, also known as etafenoxine; trade name Stresam) is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s.

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Etodroxizine

Etodroxizine (INN) (brand names Vesparax, Drimyl, Indunox, Isonox) is a first-generation antihistamine of the diphenylmethylpiperazine group which is used as a sedative/hypnotic drug in Europe and South Africa.

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Etofamide

Etofamide (INN, also known as eticlordifene) is an antiprotozoal drug used in the treatment of amoebiasis.

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Etomidate

Etomidate (USAN, INN, BAN) (marketed as Amidate) is a short-acting intravenous anaesthetic agent used for the induction of general anaesthesia and sedation for short procedures such as reduction of dislocated joints, tracheal intubation, and cardioversion.

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Etybenzatropine

Etybenzatropine (INN), also known as ethybenztropine (USAN, BAN) and tropethydrylin, is an anticholinergic/antihistamine marketed under the trade names Panolid, Ponalid, and Ponalide, which is used as an antiparkinsonian agent.

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Everolimus

No description.

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Evofosfamide

Evofosfamide (INN, USAN; formerly known as TH-302) is an investigational hypoxia-activated prodrug that is in clinical development for cancer treatment.

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Evogliptin

Evogliptin (INN; trade name Suganon) is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-4) inhibitor or "gliptin" class of drugs.

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Ex-Rad

Ex-Rad (or Ex-RAD), also known by the code name ON 01210.Na, or recilisib sodium (INN, USAN) is a drug developed by Onconova Therapeutics and the U.S. Department of Defense.

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Examorelin

Examorelin (INN) (developmental code names EP-23905, MF-6003), also known as hexarelin, is a potent, synthetic, peptidic, orally-active, centrally-penetrant, and highly selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and a growth hormone secretagogue which was developed by Mediolanum Farmaceutici.

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Ezlopitant

Ezlopitant (INN, code name CJ-11,974) is an NK1 receptor antagonist.

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Fabomotizole

Fabomotizole (INN) (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s.

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Falecalcitriol

Falecalcitriol (INN) is an analog of calcitriol.

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Fanapanel

Fanapanel (INN, code name ZK-200775), also known as MPQX, is a quinoxalinedione derivative drug which acts as a competitive antagonist of the AMPA receptor.

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Fasudil

Fasudil (INN) is a potent Rho-kinase inhibitor and vasodilator.

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Faxeladol

Faxeladol (INN, USAN) (code names GRTA-9906, GRTA-0009906, EM-906, GCR-9905, GRT-TA300) is an opioid analgesic which was developed by Grünenthal GmbH but was never marketed for medical use anywhere in the world.

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Febarbamate

Febarbamate (INN; Solium, Tymium), also known as phenobamate, is an anxiolytic and tranquilizer of the barbiturate and carbamate families which is used in Europe by itself and as part of a combination drug formulation called tetrabamate.

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Fedotozine

Fedotozine (INN; JO 1196 for the (-) tartrate salt) is an opioid drug of the arylacetamide series which acts as a peripherally-specific, selective κ1-opioid receptor agonist with preference for the κ1A subtype.

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Felbinac

Felbinac (INN, or biphenylylacetic acid) is a topical medicine, belonging to the family of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDs) of the arylacetic acid (not arylpropionic acid) class, which is used to treat muscle inflammation and arthritis.

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Femoxetine

Femoxetine (INN) (tentative brand name Malexil; developmental code name FG-4963) is a drug related to paroxetine that was being developed as an antidepressant by Danish pharmaceutical company Ferrosan in 1975 before acquisition by Novo Nordisk.

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Fenbutrazate

Fenbutrazate (INN), also known as phenbutrazate (BAN), is a psychostimulant used as an appetite suppressant under the trade names Cafilon, Filon, and Sabacid in Europe, Japan, and Hong Kong.

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Fencamfamin

Fencamfamin (INN), also known as fencamfamine or by the brand names Glucoenergan and Reactivan, is a stimulant which was developed by Merck in the 1960s.

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Fenestrel

Fenestrel (INN, USAN) (developmental code name ORF-3858) is a synthetic, nonsteroidal estrogen that was developed as a postcoital contraceptive in the 1960s but was never marketed.

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Fenethazine

Fenethazine (INN) (brand names Anergen, Contralergial, Ethysine, Etisine, Lisergan, Lysergan; former developmental code names RP-3015, SC-1627, WY-1143), or phenethazine, is a first-generation antihistamine of the phenothiazine group.

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Fenethylline

Fenethylline (BAN, USAN) is a codrug of amphetamine and theophylline which behaves as a prodrug to both of the aforementioned drugs.

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Fenisorex

Fenisorex (INN, USAN, BAN) is an amphetamine-like anorectic drug which does not appear to have ever been marketed.

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Fenofibrate

Fenofibrate, marketed as Tricor and under several other brand names, is a drug of the fibrate class.

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Fenoverine

Fenoverine (INN) is an antispasmodic drug.

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Fenpentadiol

Fenpentadiol (INN) (brand names Tredum, Trefenum; developmental code name Rd-292), also known as phenpentanediol, is a drug described as a tranquilizer and antidepressant that was formerly marketed in Europe.

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Fenquizone

Fenquizone (INN) is a diuretic, part of the class of low-ceiling sulfonamide diuretics.

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Fenretinide

Fenretinide (4-hydroxy(phenyl)retinamide; 4-HPR) (INN) is a synthetic retinoid derivative.

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Fenspiride

Fenspiride (INN, brand names Eurespal, Pneumorel and others) is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases.

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Fentonium bromide

Fentonium bromide (INN) is a belladonna derivative.

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Fenyramidol

Fenyramidol (INN) or phenyramidol (BAN, USAN), trade name Cabral, is a pharmaceutical drug which acts as a muscle relaxant.

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Fesoterodine

Fesoterodine (INN, used as the fumarate under the brand name Toviaz) is an antimuscarinic drug developed by Schwarz Pharma AG to treat overactive bladder syndrome (OAB).

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Fevipiprant

Fevipiprant (INN; code name QAW039) is a drug being developed by Novartis which acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2 or CRTh2).

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Filenadol

Filenadol (INN; Filantor; FI-2024) is an analgesic drug with antinociceptive and antiinflammatory properties.

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Filorexant

Filorexant (INN, USAN) (code name MK-6096) is an orexin antagonist which is or was under development by Merck for the treatment of insomnia.

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Finerenone

Finerenone (INN, USAN) (developmental code name BAY-94-8862) is a nonsteroidal antimineralocorticoid that is in phase III clinical trials for the treatment of chronic heart failure.

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Fingolimod

Fingolimod (INN, trade name Gilenya, Novartis) is an immunomodulating drug, mostly used for treating multiple sclerosis (MS).

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Firocoxib

Firocoxib (INN; brand names Equioxx and Previcox) is a nonsteroidal anti-inflammatory drug of the COX-2 inhibitor (coxib) class, currently approved for use in dogs and horses.

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Fispemifene

Fispemifene (INN, USAN) (developmental code name HM-101) is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that was developed for the treatment of male hypogonadism but was abandoned and never marketed.

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Fixed-dose combination (antiretroviral)

Fixed-dose combinations of antiretrovirals are multiple antiretroviral drugs combined into a single pill, which helps reduce pill burden.

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Fletikumab

Fletikumab (NNC0109-0012) (INN) is a monoclonal antibody designed for the treatment of rheumatoid arthritis.

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Florantyrone

Florantyrone (INN; also known as Fluorantyrone) is a drug used in the treatment of biliary dyskinesia.

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Flotetuzumab

Flotetuzumab (MGD006) (INN) is a humanized antibody fragment designed for the treatment of hematologic malignancies.

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Flucetorex

Flucetorex (INN) is an amphetamine which was investigated as an anorectic but does not appear to have ever been marketed.

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Fluclorolone acetonide

Fluclorolone acetonide (INN, or flucloronide, USAN, trade names Cutanit, Topicon) is a corticosteroid for topical use on the skin.

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Flucloxacillin

Flucloxacillin (INN) or floxacillin (USAN) is a narrow-spectrum beta-lactam antibiotic of the penicillin class.

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Fludeoxyglucose (18F)

Fludeoxyglucose (18F) (INN), or fludeoxyglucose F 18 (USAN and USP), also commonly called fluorodeoxyglucose and abbreviated FDG, 18F-FDG or FDG, is a radiopharmaceutical used in the medical imaging modality positron emission tomography (PET).

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Fludroxycortide

Fludroxycortide (INN, BAN, JAN), also known as flurandrenolide (USAN) and flurandrenolone, is a synthetic topical corticosteroid and is used as an anti-inflammatory treatment for use on skin irritations.

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Flugestone

Flugestone (INN, BAN), also known as flurogestone, as well as 9α-fluoro-11β,17α-dihydroxyprogesterone, is a steroidal progestin of the 17α-hydroxyprogesterone group that was never marketed.

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Flumetasone

Flumetasone (INN), also known as flumethasone (USAN), is a corticosteroid for topical use.

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Flumexadol

Flumexadol (INN) (developmental code name CERM-1841 or 1841-CERM) is a drug described and researched as a non-opioid analgesic which was never marketed.

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Fluorometholone

Fluorometholone (INN, BAN, JAN) (brand names Efflumidex, Flucon, FML Forte, FML, others), also known as 6α-methyl-9α-fluoro-11β,17α-dihydroxypregna-1,4-diene-3,20-dione, is a synthetic glucocorticoid which is used in the treatment of inflammatory eye diseases.

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Fluorouracil

Fluorouracil (5-FU), sold under the brand name Adrucil among others, is a medication used to treat cancer.

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Flupentixol

Flupentixol (INN), also known as flupenthixol (former BAN), marketed under brand names such as Depixol and Fluanxol is a typical antipsychotic drug of the thioxanthene class.

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Fluralaner

Fluralaner (INN) is a systemic insecticide and acaricide that is administered orally.

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Fluroxene

Fluroxene (INN, USAN; brand name Fluoromar), or 2,2,2-trifluoroethyl vinyl ether, is a volatile, inhalational anesthetic, and was the first halogenated hydrocarbon anesthetic to be introduced.

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Fluvastatin

Fluvastatin (INN, trade names Lescol, Canef, Vastin) is a member of the statin drug class, used to treat hypercholesterolemia and to prevent cardiovascular disease.

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Folinic acid

Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine.

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Formebolone

Formebolone (INN, BAN) (brand names Esiclene, Hubernol, Metanor), also known (confusingly) as formyldienolone, as well as 2-formyl-11α-hydroxy-17α-methyl-δ1-testosterone, is an orally active anabolic-androgenic steroid (AAS) described as an anticatabolic and anabolic drug that is or has been marketed in Spain and Italy. As an AAS, it shows some anabolic activity, though it is inferior to testosterone in terms of potency, but is said to have virtually no androgenic activity. Formebolone counteracts the catabolic effects (control of nitrogen balance) of potent glucocorticoids like dexamethasone phosphate. A close analogue, roxibolone (and its long-acting ester variant decylroxibolone), shows similar antiglucocorticoid activity to formebolone but, in contrast, is devoid of activity as an AAS. Roxibolone has been found not to bind to the glucocorticoid receptor, and it has been suggested that the antiglucocorticoid activity of roxibolone and formebolone may instead be mediated by modulation of enzymatic processes. Indeed, 11α- and 11β-hydroxyprogesterone (formebolone and roxibolone being 11α- and 11β-hydroxylated (respectively) similarly) are known to be potent inhibitors of 11β-hydroxysteroid dehydrogenase (11β-HSD), which is responsible for the biosynthesis of the potent endogenous glucocorticoids cortisol and corticosterone (from the precursors deoxycortisol and deoxycorticosterone, respectively). However, formebolone was found to be a very weak inhibitor of 11β-HSD type 2 (IC50 > 10 μM), although this specific isoenzyme of 11β-HSD is responsible for the inactivation of glucocorticoids rather than their production.

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Formetorex

Formetorex (INN), also known as formetamide or N-formylamphetamine, is an amphetamine described as an anorectic which does not appear to have ever been marketed.

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Formocortal

Formocortal (INN), also known as fluoroformylone, is a corticosteroid used in ophthalmology.

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Formoterol

Formoterol (INN) or eformoterol (former BAN) is a long-acting β2 agonist (LABA) used in the management of asthma and COPD.

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Forodesine

Forodesine (INN; also known as Immucillin H; trade names Mundesine and Fodosine) is a transition-state analog inhibitor of purine nucleoside phosphorylase studied for the treatment of patients with T-cell acute lymphoblastic leukemia (T-ALL) and for treatment of B-cell acute lymphocytic leukemia (B-ALL).

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Fosfluconazole

Fosfluconazole (INN) is a water-soluble phosphate prodrug of fluconazole — a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.

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Fospropofol

Fospropofol (INN), often used as the disodium salt (trade name Lusedra) is an intravenous sedative-hypnotic agent. It is currently approved for use in sedation of adult patients undergoing diagnostic or therapeutic procedures such as endoscopy.

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Frakefamide

Frakefamide (INN) is a synthetic, fluorinated opioid tetrapeptide with the amino acid sequence Tyr-D-Ala-(p-F)Phe-Phe-NH2 which acts as a peripherally-specific, selective μ-opioid receptor agonist.

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Fremanezumab

Fremanezumab (INN) is a humanized monoclonal antibody directed against calcitonin-related polypeptides alpha and beta.

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Frunevetmab

Frunevetmab (INN) (NV-02) is a veterinary monoclonal antibody designed for control of osteoarthritis pain in cats.

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Funapide

Funapide (INN) (former developmental code names TV-45070 and XEN402) is a novel analgesic under development by Xenon Pharmaceuticals in partnership with Teva Pharmaceutical Industries for the treatment of a variety of chronic pain conditions, including osteoarthritis, neuropathic pain, postherpetic neuralgia, and erythromelalgia, as well as dental pain.

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Furosemide

Furosemide, sold under the brand name Lasix among others, is a medication used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.

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Furostilbestrol

Furostilbestrol (INN), also known as diethylstilbestrol di(2-furoate) or simply as diesthylstilbestrol difuroate, is a synthetic, nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol that was never marketed.

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Fursultiamine

Fursultiamine (INN; chemical name thiamine tetrahydrofurfuryl disulfide or TTFD; brand names Adventan, Alinamin-F, Benlipoid, Bevitol Lipophil, Judolor, Lipothiamine) is a medication and vitamin used to treat thiamine deficiency.

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Fusafungine

Fusafungine (INN), also known as fusafungin, is an active agent used in antibiotics for treatment of nasal and throat infection.

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Fusion protein

Fusion proteins or chimeric (\kī-ˈmir-ik) proteins (literally, made of parts from different sources) are proteins created through the joining of two or more genes that originally coded for separate proteins.

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Futuximab

Futuximab (992 DS) (INN) is a chimeric monoclonal antibody designed for the treatment of cancer.

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Gadobenic acid

Gadobenic acid (INN, trade name MultiHance) is a complex of gadolinium with the ligand BOPTA.

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Gadobutrol

Gadobutrol (INN) (Gd-DO3A-butrol) is a gadolinium-based MRI contrast agent (GBCA).

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Gadoteridol

Gadoteridol (INN) is a gadolinium-based MRI contrast agent, used particularly in the imaging of the central nervous system.

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Galactosidases

Galactosidases are enzymes (glycoside hydrolases) that catalyze the hydrolysis of galactosides into monosaccharides.

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Galcanezumab

Galcanezumab (LY2951742) (INN) is a humanized monoclonal antibody directed against calcitonin-related polypeptides alpha and beta.

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Gallopamil

Gallopamil (INN) is an L-type calcium channel blocker that is an analog of verapamil.

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Gamma-Linolenic acid

Gamma-linolenic acid or GLA (γ-Linolenic acid), (INN and USAN gamolenic acid) is a fatty acid found primarily in vegetable oils.

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Ganciclovir

Ganciclovir is an antiviral medication used to treat cytomegalovirus (CMV) infections.

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Gapicomine

Gapicomine (INN) is a coronary vasodilator.

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Garenoxacin

Garenoxacin (INN) is a quinolone antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections.

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Gedocarnil

Gedocarnil (INN) is a anxiolytic of the β-carboline class related to abecarnil.

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Gefitinib

Gefitinib (ZD1839) (INN,, trade name Iressa) is a drug used for certain breast, lung and other cancers.

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Gemfibrozil

Gemfibrozil is the generic name for an oral drug used to lower lipid levels.

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Gemigliptin

Gemigliptin (rINN), previously identified as LC15-0444, is an oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs.

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Gemopatrilat

Gemopatrilat (INN) is an experimental drug that was never marketed.

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Generic drug

A generic drug is a pharmaceutical drug that is equivalent to a brand-name product in dosage, strength, route of administration, quality, performance, and intended use, but does not carry the brand name.

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Generic name

Generic name may refer to.

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Gepefrine

Gepefrine (INN; trade names Pressionorm and Wintonin), also known as 3-hydroxyamphetamine, meta-hydroxyamphetamine, and α-methyl-meta-tyramine, is an antihypotensive or sympathomimetic agent of the amphetamine family that is marketed in certain European countries.

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Gepotidacin

Gepotidacin (INN) is an experimental antibiotic that acts as a topoisomerase type II inhibitor.

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Gestaclone

Gestaclone (INN, USAN) (developmental code name SH-1040), also known as 6-chloro-1α,2α:16α,17-bismethylene-4,6-pregnadiene-3,20-dione, is a steroidal progestin of unique chemical structure derived from progesterone that was first described in 1967 and was never marketed.

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Ghrelin

Ghrelin (pronounced), the "hunger hormone", also known as lenomorelin (INN), is a peptide hormone produced by ghrelinergic cells in the gastrointestinal tract which functions as a neuropeptide in the central nervous system.

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Gilvetmab

Gilvetmab (INN) (PD1) is a veterinary monoclonal antibody.

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Gimsilumab

Gimsilumab (MORAb-022) (INN) is a human monoclonal antibody designed for the treatment of rheumatoid arthritis.

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Gitoformate

Gitoformate (INN, or pentaformylgitoxin, trade name Dynocard) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat).

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Givinostat

Givinostat (INN) or gavinostat (originally ITF2357) is a histone deacetylase inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities.

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Glecaprevir

Glecaprevir (INN) is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor that was identified jointly by AbbVie and Enanta Pharmaceuticals.

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Glemanserin

Glemanserin (INN) (developmental code name MDL-11,939) is a drug which acts as a potent and selective 5-HT2A receptor antagonist.

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Glibornuride

Glibornuride (INN) is an anti-diabetic drug from the group of sulfonylureas.

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Gliquidone

Gliquidone (INN, sold under the trade name Glurenorm) is an anti-diabetic medication in the sulfonylurea class.

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Glisoxepide

Glisoxepide (INN) is an orally available anti-diabetic drug from the group of sulfonylureas.

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Glyclopyramide

Glyclopyramide (INN, marketed under the tradename Deamelin-S) is a sulfonylurea drug used in the treatment of diabetes.

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Glycopyrronium bromide

Glycopyrronium bromide is a medication of the muscarinic anticholinergic group.

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Glymidine sodium

Glymidine sodium (INN, also known as glycodiazine; trade name Gondafon) is a sulfonamide antidiabetic drug, structurally related to the sulfonylureas.

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Gosogliptin

Gosogliptin (INN; trade name SatRx) is a drug for the treatment of type II diabetes.

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Growth hormone

Growth hormone (GH), also known as somatotropin (or as human growth hormone in its human form), is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals.

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Growth hormone therapy

Growth hormone therapy refers to the use of growth hormone (GH) as a prescription medication—it is one form of hormone therapy.

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Growth hormone–releasing hormone

Growth hormone–releasing hormone (GHRH), also known as somatocrinin or by several other names in its endogenous forms and as somatorelin (INN) in its pharmaceutical form, is a releasing hormone of growth hormone (GH).

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Guanoclor

Guanoclor (INN), also known as guanochlor, is a sympatholytic drug.

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Gustav Ehrhart

Gustav Ehrhart (21 December 1894 – 11 December 1971) was a German chemist.

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Halocarban

Halocarban (INN; also known as cloflucarban (USAN) and trifluoromethyldichlorocarbanilide; brand name Irgasan CF3) is a chemical with antibacterial properties sometimes used in deodorant and soap.

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Haloperidol

Haloperidol, marketed under the trade name Haldol among others, is a typical antipsychotic medication.

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Hemolytic-uremic syndrome

Hemolytic-uremic syndrome (HUS) is a disease characterized by a triad of hemolytic anemia (anemia caused by destruction of red blood cells), acute kidney failure (uremia), and a low platelet count (thrombocytopenia).

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Heptabarb

Heptabarb (INN; Eudan, Medapan, Medomin, Noctyn), also known as heptabarbitone (BAN) or heptabarbital, is a sedative and hypnotic drug of the barbiturate family.

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Hepzidine

Hepzidine (INN) is a tricyclic antidepressant which was never marketed.

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Heroin

Heroin, also known as diamorphine among other names, is an opioid most commonly used as a recreational drug for its euphoric effects.

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Hexapradol

Hexapradol (INN) is a psychostimulant drug which was never marketed.

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Histamine dihydrochloride

Histamine dihydrochloride (INN, trade name Ceplene) is a salt of histamine which is used as a drug for the prevention of relapse in patients diagnosed with acute myeloid leukemia (AML).

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Homarylamine

Homarylamine (INN; also known as 3,4-methylenedioxy-N-methylphenethylamine or MDMPEA) is a substituted phenethylamine.

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Homochlorcyclizine

Homochlorcyclizine (INN) is an antihistamine of the diphenylmethylpiperazine group which has been marketed in Japan since 1965.

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Homotaurine

Homotaurine (3-amino-1-propanesulfonic acid (3-APS) or tramiprosate (INN)) is a natural organic compound found in seaweed.

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Humanized antibody

Humanized antibodies are antibodies from non-human species whose protein sequences have been modified to increase their similarity to antibody variants produced naturally in humans.

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Hydrocodone/aspirin

Hydrocodone/aspirin (INNs) is an oral combination drug formulation of the opioid analgesic hydrocodone and the nonsteroidal anti-inflammatory drug (NSAID) aspirin that is used in the treatment of chronic and acute pain.

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Hydrocodone/ibuprofen

No description.

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Hydromadinone

Hydromadinone (INN), also known as 6α-chloro-17α-hydroxyprogesterone, is a steroidal progestin of the 17α-hydroxyprogesterone group which was patented in 1967 but was never marketed.

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Hyoscine

Hyoscine, also known as scopolamine, is a medication used to treat motion sickness and postoperative nausea and vomiting.

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Hypromellose

Hypromellose (INN), short for hydroxypropyl methylcellulose (HPMC), is a semisynthetic, inert, viscoelastic polymer used as eye drops, as well as an excipient and controlled-delivery component in oral medicaments, found in a variety of commercial products.

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Ibafloxacin

Ibafloxacin (INN) is a Fluoroquinolone antibiotic drug used in veterinary medicine.

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Ibandronic acid

Ibandronic acid (INN) or ibandronate sodium (USAN) is a potent bisphosphonate drug developed by Hoffman La Roche and used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer.

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Ibazocine

Ibazocine (INN, USAN) is an opioid analgesic which was never marketed.

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Ibuprofen

Ibuprofen is a medication in the nonsteroidal anti-inflammatory drug (NSAID) class that is used for treating pain, fever, and inflammation.

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Icaridin

Icaridin, also known as picaridin, is an insect repellent.

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Icodextrin

Icodextrin (INN, USAN) is a colloid osmotic agent, derived from maltodextrin, used in form of an aqueous solution for peritoneal dialysis under the trade name Extraneal, and after gynecological laparoscopic surgery for the reduction of post-surgical adhesions (fibrous bands that form between tissues and organs) under the trade name Adept.

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Idalopirdine

Idalopirdine (INN) (code names Lu AE58054) is a potent and selective 5-HT6 receptor antagonist under development by Lundbeck as an augmentation therapy for the treatment of cognitive deficits associated with Alzheimer's disease and schizophrenia.

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Idazoxan

Idazoxan (INN) is a drug which is used in scientific research.

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Identifier

An identifier is a name that identifies (that is, labels the identity of) either a unique object or a unique class of objects, where the "object" or class may be an idea, physical object (or class thereof), or physical substance (or class thereof).

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Idoxifene

Idoxifene (INN, USAN, BAN) (former developmental code names CB-7432, SB-223030), also known as pyrrolidino-4-iodotamoxifen, is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group which was under development for the treatment of breast cancer and postmenopausal osteoporosis but was never marketed.

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Iferanserin

Iferanserin (INN; VEN-309) is a drug which acts as a selective 5-HT2A receptor antagonist.

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Ilomastat

Ilomastat (INN), also known as galardin or GM6001, is a broad-spectrum matrix metalloproteinase inhibitor.

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Imagabalin

Imagabalin (INN, USAN; PD-332,334) is a drug which acts as a ligand for the α2δ subunit of the voltage-dependent calcium channel, with some selectivity for the α2δ1 subunit over α2δ2.

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Imexon

Imexon (INN, trade name Amplimexon) is a substance that is being studied in the treatment of some types of cancer, including pancreatic, lung, breast, prostate, melanoma, and multiple myeloma.

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Imgatuzumab

Imgatuzumab (INN) is a humanized monoclonal antibody designed for the treatment of cancer.

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Imidafenacin

Imidafenacin (INN) is a urinary antispasmodic of the anticholinergic class.

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Imiquimod

Imiquimod (INN) is a prescription medication that acts as an immune response modifier and is used to treat genital warts, superficial basal cell carcinoma, and actinic keratosis.

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ImmunoGen

ImmunoGen, Inc. is a biotechnology company focused on the development of antibody-drug conjugate (ADC) therapeutics for the treatment of cancer.

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Imolamine

Imolamine (INN, BAN) (brand names Angolon, Angoril, Circuline, Irri-Cor, Irrigor, Coremax) is a coronary vasodilator which is used in the treatment of angina pectoris and as a local anesthetic.

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Impromidine

Impromidine (INN) is a highly potent and specific histamine H2 receptor agonist.

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Inaperisone

Inaperisone (INN) is a muscle relaxant.

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Incadronic acid

Incadronic acid (INN, trade name Bisphonal) is a bisphosphonate.

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Inclacumab

Inclacumab (LC1004-002) (INN) is a human monoclonal antibody designed for the treatment of cardiovascular disease.

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Indacaterol

Indacaterol (INN) is an ultra-long-acting beta-adrenoceptor agonist developed by Novartis.

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Indalpine

Indalpine (INN, BAN; brand name Upstène; developmental code name LM-5008) is a selective serotonin reuptake inhibitor (SSRI) class drug that was briefly marketed.

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Indecainide

Indecainide (INN, trade name Decabid) is a class Ic antiarrhythmic agent.

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Indeloxazine

Indeloxazine (INN) (Elen, Noin) is an antidepressant and cerebral activator that was marketed in Japan and South Korea by Yamanouchi Pharmaceutical Co., Ltd for the treatment of psychiatric symptoms associated with cerebrovascular diseases, namely depression resulting from stroke, emotional disturbance, and avolition.

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Indiplon

Indiplon (INN and USAN) is a nonbenzodiazepine, hypnotic sedative that was developed in 2 formulations - an immediate release product for sleep onset and a modified-release (a.k.a. controlled-release or extended-release) version for sleep maintenance.

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Indium (111In) altumomab pentetate

Indium (111In) altumomab pentetate (INN) (USP, indium In 111 altumomab pentetate; trade name Hybri-ceaker) is a mouse monoclonal antibody linked to pentetate which acts as a chelating agent for the radioisotope indium-111.

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Indium (111In) biciromab

Indium (111In) biciromab (INN, trade name FibriScint, developed by Centocor) was a drug targeting fibrin, a protein involved in the clotting of blood.

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Indometacin

Indometacin (INN; or USAN indomethacin) is a nonsteroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling from inflammation.

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Indometacin farnesil

Indometacin farnesil (INN) is a prodrug of the nonsteroidal anti-inflammatory drug (NSAID) indometacin, designed to reduce the occurrence of side-effects by esterification of the carboxyl group on indometacin with farnesol.

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Inebilizumab

Inebilizumab (MEDI-551) (INN) is a humanized monoclonal antibody designed for the treatment of cancer, systemic sclerosis and multiple sclerosis.

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Influenza treatment

Treatments for influenza include a range of medications and therapies that are used in response to disease influenza.

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Iniparib

Iniparib (INN, previously known as BSI 201) was a drug candidate for cancer treatment.

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INN

INN may stand for.

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Inosine pranobex

Inosine pranobex (BAN; also known as inosine acedoben dimepranol (INN) or methisoprinol) an antiviral drug that is a combination of inosine and dimepranol acedoben (a salt of acetamidobenzoic acid and dimethylaminoisopropanol) in a ratio of 1 to 3.

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Insulin degludec

Insulin degludec (INN/USAN) is an ultralong-acting basal insulin analogue that was developed by Novo Nordisk under the brand name Tresiba.

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Intepirdine

Intepirdine (INN; developmental codes SB-742457, RVT-101) is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects.

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Interferon alfa

Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α) obtained from the leukocyte fraction of human blood following induction with Sendai virus.

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Interferon beta-1a

Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS).

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Interferon type I

Human type I interferons (IFNs) are a large subgroup of interferon proteins that help regulate the activity of the immune system.

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Interleukin

Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that were first seen to be expressed by white blood cells (leukocytes).

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Iodocholesterol

Iodocholesterol, or 19-iodocholesterol, also as iodocholesterol (131I) (INN), is a derivative of cholesterol with an iodine atom in the C19 position and a radiopharmaceutical.

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Iodocyanopindolol

Iodocyanopindolol (INN) is a drug related to pindolol which acts as both a β1 adrenoreceptor antagonist and a 5-HT1A receptor antagonist.

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Iofetamine (123I)

No description.

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Ioflupane (123I)

Ioflupane (123I) is the International Nonproprietary Name of a phenyltropane compound which is a neuro-imaging radiopharmaceutical drug, used by nuclear medicine physicians for the diagnosis of Parkinson's disease and the differential diagnosis of Parkinson's disease over other disorders presenting similar symptoms.

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Iomazenil

Iomazenil (also known as Ro16-0154, INN, USAN; benzodine) is an antagonist and partial inverse agonist of benzodiazepine and a potential treatment for alcohol abuse.

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Iopamidol

Iopamidol (INN, trade names Iopamiro, Isovue, Iopamiron, and Niopam) is a nonionic, low-osmolar iodinated contrast agent, developed by Bracco.

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Ioversol

Ioversol (INN) is an organoiodine compound that used as a contrast medium.

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Ipamorelin

Ipamorelin (INN) (developmental code name NNC 26-0161) is a peptide selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS) and a growth hormone secretagogue.

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Ipragliflozin

Ipragliflozin (INN, trade names Suglat) is a pharmaceutical drug for treatment of type 2 diabetes.

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Ipriflavone

Ipriflavone (INN, JAN; brand name Yambolap) is a synthetic isoflavone which may be used to inhibit bone resorption, maintain bone density and to prevent osteoporosis in postmenopausal women.

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Irampanel

Irampanel (INN, code name BIIR-561) is a drug which acts as a dual noncompetitive antagonist of the AMPA receptor and neuronal voltage-gated sodium channel blocker.

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Irbesartan

Irbesartan (INN) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.

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Isomethadone

Isomethadone (INN, BAN; Liden), also known as isoamidone, is a synthetic opioid analgesic and antitussive related to methadone that was used formerly as a pharmaceutical drug but is now no longer marketed.

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Itolizumab

Itolizumab (INN, trade name Alzumab) is a ‘first in class’ humanized IgG1 monoclonal antibody developed by Biocon.

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Itopride

Itopride (INN) (brand name Ganaton) is a prokinetic benzamide derivative unlike metoclopramide or domperidone.

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Ixabepilone

Ixabepilone (INN; also known as azaepothilone B, codenamed BMS-247550) is an epothilone B analog developed by Bristol-Myers Squibb as a chemotherapeutic medication for cancer.

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Japanese Accepted Name

A Japanese Accepted Name (JAN) is the official non-proprietary or generic name given to a pharmaceutical substance by the government of Japan.

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Ketanserin

Ketanserin (INN, USAN, BAN) (brand name Sufrexal; former developmental code name R41468) is a drug used clinically as an antihypertensive agent and in scientific research to study the serotonin system; specifically, the 5-HT2 receptor family.

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Ketazocine

Ketazocine (INN), also known as ketocyclazocine, is a benzomorphan derivative used in opioid receptor research.

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Ketocaine

Ketocaine (INN) (brand name Vericaina, former developmental code name Astra 2358 or A-2358) is an amino ether local anesthetic of the butyrophenone family used topically for pain relief which is marketed in Italy.

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Ketoconazole

Ketoconazole is a synthetic imidazole antifungal drug used primarily to treat fungal infections.

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Ketorfanol

Ketorfanol (INN, USAN) (developmental code name SBW-22), or ketorphanol, is an opioid analgesic of the morphinan family that was found to possess "potent antiwrithing activity" in animal assays but was never marketed.

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Kitasamycin

Kitasamycin (INN) is a macrolide antibiotic.

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L-DOPA

L-DOPA, also known as levodopa or L-3,4-dihydroxyphenylalanine is an amino acid that is made and used as part of the normal biology of humans, as well as some animals and plants.

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Lacosamide

Lacosamide (INN, formerly known as erlosamide, harkeroside, SPM 927, or ADD 234037), is a medication for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain.

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Lactulose

Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy.

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Lafutidine

Lafutidine (INN) is a second generation histamine H2 receptor antagonist having multimodal mechanism of action and used to treat gastrointestinal disorders.

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Lampalizumab

Lampalizumab (INN) is an antigen-binding fragment of a humanized monoclonal antibody that binds to complement factor D; it was developed as a potential treatment of geographic atrophy (atrophy of the retinal cells, retinal pigment epithelium, and choriocapillaris) secondary to age-related macular degeneration.

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Lanadelumab

Lanadelumab (INN) (alternative identifier DX-2930) is a human monoclonal antibody (class IgG1 kappa) that targets plasma kallikrein (pKal) in order to promote prevention of angioedema in patients with hereditary angioedema.

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Landiolol

Landiolol (INN) is a drug which acts as a highly cardioselective, ultra short-acting beta blocker.

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Landogrozumab

The pharmaceutical drug Landogrozumab (LY2495655) (INN) is a humanized monoclonal antibody designed for the treatment of muscle wasting disorders.

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Laniquidar

Laniquidar (INN) is a P-glycoprotein inhibitor undergoing clinical studies for acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS).

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Lanperisone

Lanperisone (INN) is a muscle relaxant.

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Lanreotide

Lanreotide (INN) is a medication used in the management of acromegaly and symptoms caused by neuroendocrine tumors, most notably carcinoid syndrome.

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Lapatinib

Lapatinib (INN), used in the form of lapatinib ditosylate (USAN) (trade names Tykerb and Tyverb) is an orally active drug for breast cancer and other solid tumours.

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Lapisteride

Lapisteride (INN; CS-891) is a dual inhibitor of both isoforms of the enzyme 5α-reductase.

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Lapyrium

Lapyrium, or lapirium, as the chloride salt lapirium chloride (INN) or lapyrium chloride (USAN), is a cationic surfactant that is used in personal care products as a biocide and antistatic agent.

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Laropiprant

Laropiprant (INN) was a drug used in combination with niacin to reduce blood cholesterol (LDL and VLDL) that is no longer sold, due to increases in side-effects with no cardiovascular benefit.

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Latrepirdine

Latrepirdine (INN, also known as dimebolin and sold as Dimebon), is an antihistamine drug which has been used clinically in Russia since 1983.

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Lavoltidine

Lavoltidine (INN, USAN, BAN; previously known as loxtidine, code name AH-23,844) is a highly potent and selective H2 receptor antagonist which was under development by Glaxo Wellcome (now GlaxoSmithKline) as a treatment for gastroesophageal reflux disease but was discontinued due to the discovery that it produced gastric carcinoid tumors in rodents.

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Lebrikizumab

Lebrikizumab (INN) is a humanized monoclonal antibody and an experimental immunosuppressive drug for the treatment of asthma that cannot be adequately controlled with inhalable glucocorticoids.

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Leconotide

Leconotide (INN) (code names CNSB004, AM336), also known as ω-conotoxin CVID, is an ω-conotoxin peptide isolated from the venom of Conus catus which is under investigation as an analgesic drug for the treatment of pain conditions.

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Lenzilumab

Lenzilumab (INN) (alternative identifier KB003) is a humanized monoclonal antibody (class IgG1 kappa) that targets colony stimulating factor 2 (CSF2)/granulocyte-macrophage colony stimulating factor (GM-CSF) designed for the treatment of chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML).

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Leptacline

Leptacline (INN) (developmental code name SD 210-32) is a drug described as a respiratory stimulant that was never marketed.

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Lestaurtinib

Lestaurtinib (rINN, codenamed CEP-701) is a tyrosine kinase inhibitor structurally related to staurosporine.

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Letermovir

Letermovir (INN; trade name Prevymis) is an antiviral drug for the treatment of cytomegalovirus (CMV) infections.

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Letolizumab

Letolizumab (INN) (BMS-986004) is a humanized monoclonal antibody designed for the treatment of inflammatory diseases.

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Levacetylmethadol

Levacetylmethadol (INN), levomethadyl acetate (USAN), OrLAAM (trade name) or levo-α-acetylmethadol (LAAM) is a synthetic opioid similar in structure to methadone.

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Levallorphan

Levallorphan (INN, BAN) (brand names Lorfan, Naloxifan, Naloxiphan), also known as levallorphan tartrate (USAN), is an opioid modulator of the morphinan family used as an opioid analgesic and opioid antagonist/antidote.

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Levamlodipine

Levamlodipine (INN), also known as levoamlodipine or S-amlodipine is a pharmacologically active enantiomer of amlodipine.

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Levoamphetamine

Levoamphetamine is a central nervous system (CNS) stimulant known to increase wakefulness and concentration in association with decreased appetite and fatigue.

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Levobupivacaine

Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group.

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Levofenfluramine

Levofenfluramine (INN), or (−)-3-trifluoromethyl-N-ethylamphetamine, also known as (−)-fenfluramine or (R)-fenfluramine, is a drug of the amphetamine family that, itself (i.e., in enantiopure form), was never marketed.

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Levoketoconazole

Levoketoconazole (INN, USAN) (developmental code name COR-003; tentative brand name Recorlev, previously NormoCort), also known as (2S,4R)-ketoconazole, is a steroidogenesis inhibitor that is under development by Strongbridge Biopharma (formerly Cortendo AB) for the treatment of Cushing's syndrome.

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Levomefolic acid

Levomefolic acid (INN) (also known as L-5-MTHF, L-methylfolate and L-5-methyltetrahydrofolate and (6S)-5-methyltetrahydrofolate, and (6S)-5-MTHF) is the primary biologically active form of folate used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine.

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Levomepromazine

Levomepromazine (INN, BAN, USAN), also known as methotrimeprazine, is a phenothiazine neuroleptic drug. It is sold in many countries under the generic name (levomepromazine) or under brand names such as Nozinan, Levoprome, Detenler, Hirnamin, Levotomin, Neurocil and many more. It is a low-potency antipsychotic (approximately half as potent as chlorpromazine) with strong analgesic, hypnotic and antiemetic properties that is primarily used in palliative care. Serious side effects include tardive dyskinesia, akathisia, abnormalities in the electrical cycle of the heart, low blood pressure and the potentially fatal neuroleptic malignant syndrome. As is typical of phenothiazine antipsychotics, levomepromazine is a "dirty drug", that is, it exerts its effects by blocking a variety of receptors, including adrenergic receptors, dopamine receptors, histamine receptors, muscarinic acetylcholine receptors and serotonin receptors.

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Levomethadone

Levomethadone (INN; L-Polamidon, L-Polamivet, Levadone, Levothyl), or levamethadone, is a synthetic opioid analgesic and antitussive which is marketed in Europe and is used for pain management and in opioid maintenance therapy.

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Levomethamphetamine

LevomethamphetamineOther names include l-methamphetamine, levodesoxyephedrine, l-desoxyephedrine, levmetamfetamine (INN and USAN).

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Levomethorphan

Levomethorphan (INN, BAN) is an opioid analgesic of the morphinan family that has never been marketed.

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Levorphanol

Levorphanol (INN; brand name Levo-Dromoran) is an opioid medication used to treat moderate to severe pain.

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Levosalbutamol

Levosalbutamol, also known as levalbuterol is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

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Levosimendan

Levosimendan (INN) is a calcium sensitiser used in the management of acutely decompensated congestive heart failure.

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Licostinel

Licostinel (INN) (code name ACEA-1021) is a competitive, silent antagonist of the glycine site of the NMDA receptor (Kb.

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Lidanserin

Lidanserin (INN; ZK-33,839) is a drug which acts as a combined 5-HT2A and α1-adrenergic receptor antagonist.

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Lidocaine

Lidocaine, also known as xylocaine and lignocaine, is a medication used to numb tissue in a specific area.

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Lifastuzumab vedotin

Lifastuzumab vedotin (DNIB0600A) (INN) is a monoclonal antibody designed for the treatment of cancer.

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Ligelizumab

Ligelizumab (QGE031) (INN) is a humanized monoclonal antibody designed for the treatment of severe asthma and chronic spontaneous urticaria.

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Lilopristone

Lilopristone (INN) (developmental code names ZK-98734, ZK-734) is a synthetic, steroidal antiprogestogen with additional antiglucocorticoid activity which was developed by Schering and was patented in 1985.

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Linagliptin

Linagliptin (INN, previously known as BI-1356, marketed under trade names Tradjenta (U.S.) and Trajenta (worldwide)) is a dipeptidyl peptidase-4 inhibitor developed by Boehringer Ingelheim for treatment of diabetes mellitus type 2.

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Lirilumab

Lirilumab (INN) is a human monoclonal antibody designed for the treatment of cancer.

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List of antineoplastic agents

This is a list of antineoplastic agents used to treat cancer.

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List of chemical compounds with unusual names

Chemical nomenclature, replete as it is with compounds with complex names, is a repository for some very peculiar and sometimes startling names.

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List of drugs: 1-9

No description.

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List of drugs: A-Ab

No description.

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List of drugs: Ac

No description.

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List of drugs: Ad-Ak

No description.

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List of drugs: Al

No description.

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List of drugs: Am

No description.

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List of drugs: An-Ap

No description.

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List of drugs: Aq-Ar

No description.

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List of drugs: As-Az

No description.

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List of drugs: Ba

No description.

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List of drugs: Be

No description.

New!!: International nonproprietary name and List of drugs: Be · See more »

List of drugs: Bi-Bo

No description.

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List of drugs: Br

No description.

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List of drugs: Bs-Bz

No description.

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List of drugs: C-Ca

No description.

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List of drugs: Cb-Ce

No description.

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List of drugs: Cf-Ch

No description.

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List of drugs: Ci

No description.

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List of drugs: Cj-Cl

No description.

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List of drugs: Cm-Co

No description.

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List of drugs: Cp-Cz

No description.

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List of drugs: D-Dd

No description.

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List of drugs: De

No description.

New!!: International nonproprietary name and List of drugs: De · See more »

List of drugs: Df-Di

No description.

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List of drugs: Do

No description.

New!!: International nonproprietary name and List of drugs: Do · See more »

List of drugs: Dr-Dy

No description.

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List of drugs: E-El

No description.

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List of drugs: Em-Ep

No description.

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List of drugs: Eq-Es

No description.

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List of drugs: Et

No description.

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List of drugs: Eu-Ex

No description.

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List of drugs: Fa

No description.

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List of drugs: Fe

No description.

New!!: International nonproprietary name and List of drugs: Fe · See more »

List of drugs: Fi

No description.

New!!: International nonproprietary name and List of drugs: Fi · See more »

List of drugs: Fl

No description.

New!!: International nonproprietary name and List of drugs: Fl · See more »

List of drugs: Fm-Ft

No description.

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List of drugs: G

No description.

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List of drugs: H-He

No description.

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List of drugs: Hf-Hz

No description.

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List of drugs: Ia-Il

No description.

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List of drugs: Im-In

No description.

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List of drugs: Io-Ip

No description.

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List of drugs: Iq-Iv

No description.

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List of drugs: J

No description.

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List of drugs: K

No description.

New!!: International nonproprietary name and List of drugs: K · See more »

List of drugs: La

No description.

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List of drugs: Le

No description.

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List of drugs: Lf-Ln

No description.

New!!: International nonproprietary name and List of drugs: Lf-Ln · See more »

List of drugs: Lo

No description.

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List of drugs: Ls-Ly

No description.

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List of drugs: M-Md

No description.

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List of drugs: Me-Meo

No description.

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List of drugs: Mep-Mes

No description.

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List of drugs: Met

No description.

New!!: International nonproprietary name and List of drugs: Met · See more »

List of drugs: Meu-Mi

No description.

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List of drugs: Mo

No description.

New!!: International nonproprietary name and List of drugs: Mo · See more »

List of drugs: Mp-My

No description.

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List of drugs: N-Na

No description.

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List of drugs: Nb-Nh

No description.

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List of drugs: Ni

No description.

New!!: International nonproprietary name and List of drugs: Ni · See more »

List of drugs: Nj-Nz

No description.

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List of drugs: O-Op

No description.

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List of drugs: Oq-Ow

No description.

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List of drugs: Ox-Oz

No description.

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List of drugs: P-Pa

No description.

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List of drugs: Pb-Pe

No description.

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List of drugs: Pf-Ph

No description.

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List of drugs: Pi

No description.

New!!: International nonproprietary name and List of drugs: Pi · See more »

List of drugs: Pj-Pra

No description.

New!!: International nonproprietary name and List of drugs: Pj-Pra · See more »

List of drugs: Prb-Prn

No description.

New!!: International nonproprietary name and List of drugs: Prb-Prn · See more »

List of drugs: Pro-Prz

No description.

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List of drugs: Ps-Pz

No description.

New!!: International nonproprietary name and List of drugs: Ps-Pz · See more »

List of drugs: Q

No description.

New!!: International nonproprietary name and List of drugs: Q · See more »

List of drugs: R-Rb

No description.

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List of drugs: Re

No description.

New!!: International nonproprietary name and List of drugs: Re · See more »

List of drugs: Rf-Rz

No description.

New!!: International nonproprietary name and List of drugs: Rf-Rz · See more »

List of drugs: S-Sd

No description.

New!!: International nonproprietary name and List of drugs: S-Sd · See more »

List of drugs: Se-Sh

No description.

New!!: International nonproprietary name and List of drugs: Se-Sh · See more »

List of drugs: Si

No description.

New!!: International nonproprietary name and List of drugs: Si · See more »

List of drugs: Sj-So

No description.

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List of drugs: Sp-Sub

No description.

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List of drugs: Suc-Sul

No description.

New!!: International nonproprietary name and List of drugs: Suc-Sul · See more »

List of drugs: Sum-Sz

No description.

New!!: International nonproprietary name and List of drugs: Sum-Sz · See more »

List of drugs: T-Td

No description.

New!!: International nonproprietary name and List of drugs: T-Td · See more »

List of drugs: Te

No description.

New!!: International nonproprietary name and List of drugs: Te · See more »

List of drugs: Tf-Th

No description.

New!!: International nonproprietary name and List of drugs: Tf-Th · See more »

List of drugs: Ti

No description.

New!!: International nonproprietary name and List of drugs: Ti · See more »

List of drugs: Tj-Tq

No description.

New!!: International nonproprietary name and List of drugs: Tj-Tq · See more »

List of drugs: Tr-Tri

No description.

New!!: International nonproprietary name and List of drugs: Tr-Tri · See more »

List of drugs: Trj-Tz

No description.

New!!: International nonproprietary name and List of drugs: Trj-Tz · See more »

List of drugs: U

No description.

New!!: International nonproprietary name and List of drugs: U · See more »

List of drugs: V-Ve

No description.

New!!: International nonproprietary name and List of drugs: V-Ve · See more »

List of drugs: Vf-Vz

No description.

New!!: International nonproprietary name and List of drugs: Vf-Vz · See more »

List of drugs: W

No description.

New!!: International nonproprietary name and List of drugs: W · See more »

List of drugs: X

No description.

New!!: International nonproprietary name and List of drugs: X · See more »

List of drugs: Y

No description.

New!!: International nonproprietary name and List of drugs: Y · See more »

List of drugs: Z

No description.

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List of local anesthetics

This is a list of local anesthetic agents.

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List of pharmaceutical compound number prefixes

This list of pharmaceutical compound number prefixes details a pharmaceutical drug labeling standard.

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List of pharmaceutical manufacturers in the United Kingdom

This is a list of manufacturers and suppliers of pharmaceuticals with operations in the United Kingdom.

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List of psychiatric medications by condition treated

This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress.

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List of psychotropic medications

List of medications which are used to treat psychiatric conditions that are on the market in the United States (this list is incomplete; the title of the entry is "List of Psychotropic Medications" and what follows is a list of psychiatric drugs - not all psychotropic agents are used to treat psychiatric conditions. A couple of examples are 'Tramadol' and 'Morphine').

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List of therapeutic monoclonal antibodies

This is a list of therapeutic, diagnostic and preventive monoclonal antibodies, antibodies that are clones of a single parent cell.

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List of veterinary drugs

This article lists veterinary pharmaceutical drugs alphabetically by name.

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Lobenzarit

Lobenzarit (INN) is a drug used in the treatment of arthritis.

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Lomerizine

Lomerizine (INN) (also known as KB-2796) is a diphenylpiperazine class L-type and T-type calcium channel blocker.

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Lometraline

Lometraline (INN; developmental code name CP-14,368) is a drug and an aminotetralin derivative.

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Lomevactone

Lomevactone (INN) (developmental code name DR-250) is a drug described as a psychostimulant and antidepressant which was synthesized and assayed in the 1980s but was never marketed.

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Lomitapide

Lomitapide (INN, marketed as Juxtapid in the US and as Lojuxta in the EU) is a drug used as a lipid-lowering agent for the treatment of familial hypercholesterolemia, developed by Aegerion Pharmaceuticals.

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Lomustine

Lomustine (INN), abbreviated as CCNU (original brand name (formerly available) is CeeNU, now marketed as Gleostine), is an alkylating nitrosourea compound used in chemotherapy.

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Lonaprisan

Lonaprisan (INN, USAN) (developmental code names ZK-230211, BAY 86-5044, ZK-PRA) is a synthetic, steroidal antiprogestogen which was under development by Bayer HealthCare Pharmaceuticals for the treatment of endometriosis, dysmenorrhea, and breast cancer but was discontinued.

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Long-acting beta-adrenoceptor agonist

Long-acting β adrenoceptor agonists (LABAs, more specifically, long-acting β2 adrenergic receptor agonists) are usually prescribed for moderate-to-severe persistent asthma patients or patients with chronic obstructive pulmonary disease (COPD).

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Lopirazepam

Lopirazepam (INN) is a short-acting benzodiazepine analog of the pyridodiazepine type (specifically, the pyridodiazepine analog of lorazepam) with anxiolytic and hypnotic properties.

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Lorbamate

Lorbamate (INN; Abbott-19,957) is a muscle relaxant and tranquilizer of the carbamate family which was never marketed.

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Lorediplon

Lorediplon (INN) is a nonbenzodiazepine of the pyrazolopyrimidine family that is being pursued as a treatment for insomnia but has not completed development.

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Lormetazepam

Lormetazepam (INN), or methyl-lorazepam, marketed as Noctamid among others, is a drug which is a short to intermediate acting 3-hydroxy benzodiazepine derivative.

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Lornoxicam

Lornoxicam (INN, or chlortenoxicam; trade name Xefo, among others) is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic (pain relieving), anti-inflammatory and antipyretic (fever reducing) properties.

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Lorpiprazole

Lorpiprazole (INN) (brand name Normarex) is a marketed anxiolytic drug of the phenylpiperazine group.

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Losigamone

Losigamone (INN) is an investigational drug for the treatment of epilepsy.

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Loxoprofen

Loxoprofen (INN) is a nonsteroidal anti-inflammatory drug (NSAID) in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others.

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Lubiprostone

Lubiprostone (rINN, marketed under the trade name Amitiza among others) is a medication used in the management of chronic idiopathic constipation, predominantly irritable bowel syndrome-associated constipation in women and opioid-induced constipation.

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Lucimycin

Lucimycin (INN, also known as lucensomycin and etruscomycin) is a macrolide antibiotic synthesized by the bacterium Streptomyces lucensis.

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Lucitanib

Lucitanib (INN) is a drug that is being investigated by Clovis Oncology in clinical trials for the treatment of advanced solid tumours including metastatic breast cancer.

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Lufuradom

Lufuradom (INN) is a drug and benzodiazepine derivative which, unlike other benzodiazepines, is described as an analgesic.

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Lulizumab pegol

Lulizumab pegol (BMS-931699) (INN) is a monoclonal antibody designed for the treatment of autoimmune diseases.

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Luminespib

Luminespib (INN, previously known as NVP-AUY922) is an experimental drug candidate for the treatment of cancer.

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Lumiracoxib

Lumiracoxib (rINN) is a carboxylic acid COX-2 selective inhibitor nonsteroidal anti-inflammatory drug, manufactured by Novartis and still sold in few countries, including Mexico, Ecuador and the Dominican Republic, under the trade name Prexige (sometimes misquoted as "Prestige" by the media).

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Lumretuzumab

Lumretuzumab (RG7116) (INN) is a humanized monoclonal antibody designed for the treatment of cancer.

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Lundbeck

H.

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Lurosetron

Lurosetron (INN) is a serotonin 5-HT3 receptor antagonist.

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Macrogol

Macrogol is the international nonproprietary name for polyethylene glycol (PEG) used in medicine.

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Mafenide

Mafenide (INN; usually as mafenide acetate, trade name Sulfamylon) is a sulfonamide-type medication used as an antibiotic.

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Mafosfamide

No description.

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Magaldrate

Magaldrate (INN) is a common antacid drug that is used for the treatment of duodenal and gastric ulcers, esophagitis from gastroesophageal reflux.

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Maitansine

Maitansine (INN), or maytansine (USAN), is a cytotoxic agent.

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Malotilate

Malotilate (INN) is a drug used in the treatment of liver disease.

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Management of HIV/AIDS

The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs in an attempt to control HIV infection.

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Manidipine

Manidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.

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Mannomustine

Mannomustine (INN), also known as mannitol nitrogen mustard, tradename Degranol is an old alkylating antineoplastic agent from the group of nitrogen mustards.

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Mannosulfan

Mannosulfan (INN) is an alkylating agent used in the treatment of cancer.

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Mapracorat

Mapracorat (INN, code names BOL-303242-X, ZK-245186) is an anti-inflammatory drug belonging to the experimental class of selective glucocorticoid receptor agonists (SEGRAs).

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Maraviroc

Maraviroc (INN, brand-named Selzentry, or Celsentri outside the U.S.) is an antiretroviral drug in the CCR5 receptor antagonist class used in the treatment of HIV infection.

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Maropitant

Maropitant (INN, trade name Cerenia, used as maropitant citrate (USAN), is a neurokinin-1 (NK1) receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007 for use in dogs, and in 2012 for cats. Maropitant also has mild pain-relieving, anti-anxiety, and anti-inflammatory effects.

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MDMA

3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (E), is a psychoactive drug used primarily as a recreational drug.

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Mebhydrolin

Mebhydrolin (INN) or mebhydroline is an antihistamine.

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Mecamylamine

Mecamylamine (INN, BAN; or mecamylamine hydrochloride (USAN); brand names Inversine, Vecamyl) is a non-selective, non-competitive antagonist of the nicotinic acetylcholine receptors (nAChRs) that was introduced in the 1950s as an antihypertensive drug.

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Mecasermin rinfabate

Mecasermin rinfabate (INN, USAN) (brand name Iplex), also known as /, is a drug consisting of recombinant human insulin-like growth factor 1 (IGF-1) and recombinant human insulin-like growth factor binding protein-3 (IGFBP-3) which is used for the treatment of amyotrophic lateral sclerosis (Lou Gehrig's disease).

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Mecillinam

Mecillinam (INN) or amdinocillin (USAN) is an extended-spectrum penicillin antibiotic of the amidinopenicillin class that binds specifically to penicillin binding protein 2 (PBP2), and is only considered to be active against Gram-negative bacteria.

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Meclizine

Meclizine (INN, or meclozine) is an antihistamine of the diphenylmethylpiperazine group considered to be an antiemetic.

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Meclocycline

Meclocycline (INN) is a tetracycline antibiotic.

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Meclofenoxate

Meclofenoxate (INN, BAN) (brand name Lucidril), also known as centrophenoxine, is a cholinergic nootropic used as a dietary supplement and drug in the treatment of symptoms of senile dementia and Alzheimer's disease.

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Medication package insert

A package insert (formally prescribing information in the United States; in Europe, patient information leaflet or instructions for use for human medicines and package leaflet for veterinary medicines) is a document provided along with a prescription or over-the-counter medication to provide additional information about that drug.

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Medrysone

Medrysone (INN, USAN) (brand names HMS, Medrocort, others; former developmental code name NSC-63278), also known as hydroxymethylprogesterone, methylhydroxyprogesterone, or hydroxymesterone, as well as 6α-methyl-11β-hydroxyprogesterone or 6α-methyl-11β-hydroxypregn-4-ene-3,20-dione, is a synthetic glucocorticoid that is or has been used in the treatment of inflammatory eye diseases.

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Mefexamide

Mefexamide (INN, USAN) (brand names Perneuron, Peroxinorm, Timodyne; developmental code name ANP-297), also known as mefexadyne and mexephenamide, is a central nervous system stimulant that is no longer marketed.

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Mefruside

Mefruside (INN) is a diuretic indicated for the treatment of edema and hypertension.

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Meglutol

Meglutol (INN, also known as 3-hydroxy-3-methylglutaric acid, β-hydroxy-β-methylglutaric acid, and dicrotalic acid) is a hypolipidemic agent.

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Meldonium

Meldonium (INN; trade name Mildronate, among others) is a limited-market pharmaceutical, developed in 1970 by Ivars Kalviņš at the USSR Latvia Institute of Organic Synthesis, and now manufactured by the Latvian pharmaceutical company Grindeks and several generic manufacturers.

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Melengestrol

Melengestrol (INN, BAN) is a steroidal progestin of the 17α-hydroxyprogesterone group and an antineoplastic drug which was never marketed.

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Menabitan

Menabitan (INN; SP-204), or menabitan hydrochloride (USAN), is a synthetic drug which acts as a potent cannabinoid receptor agonist.

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Menatetrenone

Menatetrenone (INN), also known as MK-4, is a vitamin K compound used as a hemostatic agent, and also as adjunctive therapy for the pain of osteoporosis.

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Mepacrine

Mepacrine (INN), also called quinacrine (USAN) or by the trade name Atabrine, is a drug with several medical applications.

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Mepiprazole

Mepiprazole (INN, BAN) (brand name Psigodal) is an anxiolytic drug of the phenylpiperazine group with additional antidepressant properties that is marketed in Spain.

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Mertansine

Mertansine, also called DM1 (and in some of its forms emtansine), is a thiol-containing maytansinoid that for therapeutic purposes is attached to a monoclonal antibody through reaction of the thiol group with a linker structure to create an antibody-drug conjugate (ADC).

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Mespirenone

Mespirenone (INN) (developmental code name ZK-94679), also known as Δ1-15β,16β-methylenespironolactone, is a steroidal antimineralocorticoid of the spirolactone group related to spironolactone that was never marketed.

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Mesylate

In chemistry, a mesylate is any salt or ester of methanesulfonic acid (CH3SO3H).

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Metaglycodol

Metaglycodol (INN) is a drug described as a tranquilizer which was never marketed.

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Metahexamide

Metahexamide (INN) is an anti-diabetic drug from the group of sulfonylureas.

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Metamfepramone

Metamfepramone (INN, also known as dimethylcathinone, dimethylpropion, and dimepropion (BAN)) is a stimulant drug of the phenethylamine, and cathinone chemical classes.

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Metaraminol

Metaraminol (INN; trade names Aramine, Metaramin, and Pressonex), also known as metaradrine, a stereoisomer of ''meta''-hydroxynorephedrine (3,β-dihydroxyamphetamine), is a potent sympathomimetic amine used in the prevention and treatment of hypotension, particularly as a complication of anesthesia.

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Metformin

Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight.

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Methacholine

Methacholine (INN, USAN) (trade name Provocholine) is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system.

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Methamphetamine

Methamphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity.

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Methitural

Methitural (INN; Neraval, Thiogenal), or methitural sodium, also known as methioturiate, is a barbiturate derivative which was marketed in the 1950s in Europe (in Germany and Italy) as an ultra-short-acting intravenous anesthetic.

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Methylene blue

Methylene blue, also known as methylthioninium chloride, is a medication and dye.

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Methylnaltrexone

Methylnaltrexone (MNTX, brand name Relistor), used in form of methylnaltrexone bromide (INN, USAN, BAN), is one of the newer agents of peripherally acting μ-opioid antagonists that act to reverse some of the side effects of opioid drugs such as constipation without affecting analgesia or precipitating withdrawals.

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Methylphenobarbital

Methylphenobarbital (INN), also known as mephobarbital (USAN, JAN) and mephobarbitone (BAN), marketed under brand names such as Mebaral, Mephyltaletten, Phemiton, and Prominal, is a drug which is a barbiturate derivative and is used primarily as an anticonvulsant, but also as a sedative and anxiolytic.

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Meticrane

Meticrane (INN) is a diuretic.

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Metildigoxin

Metildigoxin (INN, or medigoxin BAN, or methyldigoxin) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat).

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Metirosine

Metirosine (INN and BAN; α-Methyltyrosine, Metyrosine USAN, AMPT) is an antihypertensive drug.

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Metisazone

Methisazone (USAN) or metisazone (INN) is an antiviral drug that works by inhibiting mRNA and protein synthesis, especially in pox viruses.

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Metkefamide

Metkefamide (INN; LY-127,623), or metkephamid acetate (USAN), but most frequently referred to simply as metkephamid, is a synthetic opioid pentapeptide and derivative of Metenkephalin with the amino acid sequence Tyr-D-Ala-Gly-Phe-(N-Me)-Met-NH2.

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Metofoline

Metofoline (INN), also known as methofoline (USAN), is an opioid analgesic drug discovered in the 1950s by a team of Swiss researchers at Hoffmann-La Roche.

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Metogest

Metogest (INN, USAN) (developmental code name SC-14207), also known as 16,16-dimethyl-19-nortestosterone, is a steroidal antiandrogen that was patented in 1975 and investigated as a treatment for acne but was never marketed.

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Metopimazine

Metopimazine (INN) is a phenothiazine antiemetic.

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Metrifonate

Metrifonate (INN) or trichlorfon (USAN) is an irreversible organophosphate acetylcholinesterase inhibitor.

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Metynodiol

Metynodiol (INN), or methynodiol, also known as 11β-methyletynodiol, is a steroidal progestin of the 19-nortestosterone group that was synthesized in the 1960s but was never marketed.

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Mexiletine

Mexiletine (INN) (sold under the trade name Mexitil) is a non-selective voltage-gated sodium channel blocker which belongs to the Class IB anti-arrhythmic group of medicines.

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Micronomicin

Micronomicin (INN) is an aminoglycoside antibiotic for use on the eye.

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Milacemide

Milacemide (INN) is an MAO-B inhibitor and glycine prodrug.

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Minamestane

Minamestane (INN (former developmental code name FCE-24,928) is a steroidal aromatase inhibitor which was under development by Farmitalia-Carlo Erba as an antineoplastic agent in the mid-1990s but was never marketed. Unlike other steroidal aromatase inhibitors such as formestane and exemestane, minamestane does not have androgenic properties.

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Minaprine

Minaprine (INN, USAN, BAN) (brand names Brantur, Cantor) is a monoamine oxidase inhibitor antidepressant drug that was used in France for the treatment of depression until it was withdrawn from the market in 1996 because it caused convulsions.

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Mipomersen

Mipomersen (INN; trade name Kynamro) is used to treat homozygous familial hypercholesterolemia and is administered by subcutaneous injection.

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Miproxifene

Miproxifene (INN) (former developmental code name DP-TAT-59) is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that was never marketed.

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Miravirsen

Miravirsen (INN; codenamed SPC3649) is an experimental drug for the treatment of hepatitis C, being developed by Santaris Pharma.

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Mirikizumab

Mirikizumab (LY3074828) (INN) is a human monoclonal antibody designed for the treatment of autoimmune diseases.

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Miroprofen

Miroprofen (INN) is an analgesic and NSAID, meaning that it has anti-inflammatory, antipyretic and antiplatelet aggregation activity.

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Mitiglinide

Mitiglinide (INN, trade name Glufast) is a drug for the treatment of type 2 diabetes.

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Mitomycins

The mitomycins are a family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae. They include mitomycin A, mitomycin B, and mitomycin C. When the name mitomycin occurs alone, it usually refers to mitomycin C, its international nonproprietary name.

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Mitotane

Mitotane, sold under the brand name Lysodren, is a steroidogenesis inhibitor and cytostatic antineoplastic medication which is used in the treatment of adrenocortical carcinoma and Cushing's syndrome.

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Mitozolomide

Mitozolomide (INN) is an antineoplastic.

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Mizoribine

Mizoribine (INN, trade name Bredinin) is an immunosuppressive drug.

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Modimelanotide

Modimelanotide (INN) (code names AP-214, ABT-719, ZP-1480) is a melanocortinergic peptide drug derived from α-melanocyte-stimulating hormone (α-MSH) which was under development by, at different times, Action Pharma, Abbott Laboratories, AbbVie, and Zealand for the treatment of acute kidney injury.

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Mofezolac

Mofezolac (INN) is a nonsteroidal anti-inflammatory drug (NSAID).

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Momelotinib

Momelotinib (INN, formerly GS-0387, CYT-387) is an inhibitor of Janus kinases JAK1 and JAK2, acting as an ATP competitor with IC50 values of 11 and 18 nM, respectively.

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Mometasone

Mometasone (INN, BAN), is a synthetic, steroidal glucocorticoid or corticosteroid that was never marketed.

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Monomethyl auristatin E

Monomethyl auristatin E (MMAE) is a synthetic antineoplastic agent.

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Monomethyl auristatin F

Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent.

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Morforex

Morforex (INN; Bo 637), also referable to as N-morpholinoethylamphetamine, is an anorectic which was never marketed.

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Motavizumab

Motavizumab (proposed INN, trade name Numax) is a humanized monoclonal antibody.

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Moxonidine

Moxonidine (INN) is a new-generation alpha-2/imidazoline receptor agonist antihypertensive drug licensed for the treatment of mild to moderate essential hypertension.

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Mozavaptan

Mozavaptan (INN) is a vasopressin receptor antagonist marketed by Otsuka.

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Murodermin

Murodermin (INN), also known as recombinant murine epidermal growth factor (rmEGF), is a recombinant form of mouse epidermal growth factor (EGF) and an EGF receptor agonist which was never marketed.

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N-Acetylaspartylglutamic acid

N-Acetylaspartylglutamic acid (N-acetylaspartylglutamate or NAAG) is a peptide neurotransmitter and the third-most-prevalent neurotransmitter in the mammalian nervous system.

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N-Phenylacetyl-L-prolylglycine ethyl ester

N-Phenylacetyl-L-prolylglycine ethyl ester is promoted as a nootropic and is a prodrug of cycloprolylglycine.

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Nadifloxacin

Nadifloxacin (INN, brand names Acuatim, Nadiflox, Nadoxin, Nadixa, activon) is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris.

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Nafamostat

Nafamostat (INN), a synthetic serine protease inhibitor, is an anticoagulant.

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Nafoxadol

Nafoxadol (INN) is an analgesic drug which was never marketed.

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Nafoxidine

Nafoxidine (INN) (developmental code names U-11,000A, NSC-70735), or nafoxidine hydrochloride (USAN), is a nonsteroidal selective estrogen receptor modulator (SERM) or partial antiestrogen of the triphenylethylene group that was developed for the treatment of advanced breast cancer by Upjohn in the 1970s but was never marketed.

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Naftidrofuryl

Naftidrofuryl (INN), also known as nafronyl or as the oxalate salt naftidrofuryl oxalate or nafronyl oxalate, is a vasodilator used in the management of peripheral and cerebral vascular disorders.

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Naftopidil

Naftopidil (INN, marketed under the brand name Flivas) is a drug used in benign prostatic hypertrophy which acts as a selective α1-adrenergic receptor antagonist or alpha blocker.

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Naldemedine

Naldemedine (INN, USAN; S-297,995, Symproic) is a peripherally-selective μ-opioid receptor antagonist developed by Shionogi which is approved for the treatment of opioid-induced constipation in adult patients with chronic non-cancer pain.

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Nalfurafine

Nalfurafine (INN, USAN) (brand name Remitch; former developmental code names TRK-820, AC-820, MT-9938) is an antipruritic (anti-itch drug) that is marketed in Japan for the treatment of uremic pruritus in individuals with chronic kidney disease undergoing hemodialysis.

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Nalmexone

Nalmexone (INN) (code names EN-1620A, UM-592), or nalmexone hydrochloride (USAN), is a semisynthetic, opioid partial agonist or mixed agonist-antagonist with both analgesic and narcotic antagonist properties that was never marketed.

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Naloxegol

Naloxegol (INN; PEGylated naloxol; trade names Movantik and Moventig) is a peripherally selective opioid antagonist developed by AstraZeneca, licensed from Nektar Therapeutics, for the treatment of opioid-induced constipation.

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Naltalimide

Naltalimide (INN) (code name TRK-130, formerly TAK 363) is a novel, centrally-acting opioid drug which is under development by Takeda and Toray for the treatment of overactive bladder/urinary incontinence.

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Naluzotan

Naluzotan (INN, USAN; PRX-00023) is a serotonergic drug of the phenylpiperazine class that was under investigation by EPIX Pharmaceuticals Inc for the treatment of generalized anxiety disorder and major depressive disorder.

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Nateglinide

Nateglinide (INN, trade name Starlix) is a drug for the treatment of type 2 diabetes.

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Necitumumab

Necitumumab (INN) is a recombinant human IgG1 monoclonal antibody used as an antineoplastic.

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Nedaplatin

Nedaplatin (INN, marketed under the tradename Aqupla) is a platinum-based antineoplastic drug which is used for cancer chemotherapy.

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Nelivaptan

Nelivaptan (INN) (developmental codename SSR-149,415) is a selective, orally active, non-peptide vasopressin receptor antagonist selective for the V1B subtype.

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Nepadutant

Nepadutant (INN) (code name MEN-11420) is a glycosylated bicyclic cyclohexapeptide drug which acts as a highly selective NK2 receptor antagonist.

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Nepicastat

Nepicastat (INN, codenamed SYN117, RS-25560-197) is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine.

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Neridronic acid

Neridronic acid (INN; the anion is called neridronate) is a bisphosphonate.

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Neticonazole

Neticonazole (INN) is an imidazole antifungal for the treatment of fungal skin infections.

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Nexeridine

Nexeridine (INN), or as nexeridine hydrochloride (USAN) (code name Compound 673-082), is an opioid analgesic with a similar structure to those of pethidine and tramadol.

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Niacin

Niacin, also known as nicotinic acid, is an organic compound and a form of vitamin B3, an essential human nutrient.

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Niaprazine

Niaprazine (INN) (brand name Nopron) is a sedative-hypnotic drug of the phenylpiperazine group.

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Nicergoline

Nicergoline (INN, marketed under the trade name Sermion) is an ergot derivative used to treat senile dementia and other disorders with vascular origins.

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Nifekalant

Nifekalant (INN) is a class III antiarrhythmic agent approved in Japan for the treatment of arrhythmias and ventricular tachycardia.

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Nifuroxazide

Nifuroxazide (INN) is an oral nitrofuran antibiotic, patented since 1966 and used to treat colitis and diarrhoea in humans and non-humans.

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Nifurtoinol

Nifurtoinol (rINN, trade name Urfadyn) is a nitrofuran-derivative antibiotic used in the treatment of urinary tract infections.

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Nimorazole

Nimorazole (INN) is a nitroimidazole anti-infective.

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Nisobamate

Nisobamate (INN; W-1015) is a tranquilizer of the carbamate family which was never marketed.

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Nisoldipine

Nisoldipine (INN) is a calcium channel blocker of the dihydropyridine class.

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Nitecapone

Nitecapone (INN; OR-462) is a drug which acts as a selective inhibitor of the enzyme catechol ''O''-methyl transferase (COMT).

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Nitisinone

Nitisinone (INN), also known as NTBC (an abbreviation of its full chemical name) is a medication used to slow the effects of hereditary tyrosinemia type 1.

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Nitrofurazone

Nitrofurazone (INN, trade name Furacin) is an antimicrobial organic compound belonging to the furan class.

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Nitromifene

Nitromifene (INN; also as the citrate salt nitromifene citrate (USAN), developmental code names CI-728, CN-5518, CN-55945) is a nonsteroidal selective estrogen receptor modulator (SERM) related to triphenylethylenes like tamoxifen that was never marketed.

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Nomenclature of monoclonal antibodies

The nomenclature of monoclonal antibodies is a naming scheme for assigning generic, or nonproprietary, names to monoclonal antibodies.

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Noracymethadol

Noracymethadol (INN) is a synthetic opioid analgesic related to methadone that was never marketed.

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Nordazepam

Nordazepam (INN; marketed under brand names Nordaz, Stilny, Madar, Vegesan, and Calmday; also known as nordiazepam, desoxydemoxepam, and desmethyldiazepam) is a 1,4-benzodiazepine derivative.

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Nordinone

Nordinone (INN), also known as 11α-hydroxy-17,17-dimethyl-18-norandrosta-4,13-dien-3-one, is a naturally occurring steroid with antiandrogen properties isolated as a metabolite from the fungus Monocillium nordinii.

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Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.

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Norepinephrine (medication)

Norepinephrine, also known as noradrenaline, is a medication used to treat people with very low blood pressure.

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Norfenefrine

Norfenefrine (INN) or meta-octopamine (3-octopamine), also known as 3,β-dihydroxyphenethylamine, is an adrenergic agent used as a sympathomimetic drug which is marketed in Europe, Japan, and Mexico.

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Normethadone

Normethadone (INN, BAN; brand names Cophylac, Dacartil, Eucopon, Mepidon, Noramidone, Normedon, and others), also known as desmethylmethadone or phenyldimazone, is a synthetic opioid analgesic and antitussive agent.

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Norpipanone

Norpipanone (INN, BAN; Hexalgon) is an opioid analgesic related to methadone which was developed in Germany and distributed in Hungary, Argentina, and other countries.

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Novartis v. Union of India & Others

Novartis v. Union of India & Others is a landmark decision by a two-judge bench of the Indian Supreme Court on the issue of whether Novartis could patent Gleevec in India, and was the culmination of a seven-year-long litigation fought by Novartis.

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Oblimersen

Oblimersen (INN, trade name Genasense; also known as Augmerosen and bcl-2 antisense oligodeoxynucleotide G3139) is an antisense oligodeoxyribonucleotide being studied as a possible treatment for several types of cancer, including chronic lymphocytic leukemia, B-cell lymphoma, and breast cancer.

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Ocfentanil

Ocfentanil (INN) (also called A-3217) is a potent synthetic opioid structurally related to fentanyl that was developed in the early 1990s as one of a series of potent naloxone-reversible opioids in an attempt to obtain an opioid that had better therapeutic indices in terms of cardiovascular effects and respiratory depression as compared to fentanyl.

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Octatropine methylbromide

Octatropine methylbromide (INN) or anisotropine methylbromide (USAN), trade names Valpin, Endovalpin, Lytispasm and others, Retrieved on August 31, 2008 through Google Book Search.

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Octotiamine

Octotiamine (INN, JAN; Gerostop, Neuvita, Neuvitan), also known as thioctothiamine, is an analogue of vitamin B1 which is used in Japan and Finland.

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Odalasvir

Odalasvir (INN, previously known as ACH-3102) is an investigational new drug in development for the treatment of hepatitis C. It is an NS5A inhibitor.

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Odanacatib

Odanacatib (INN; codenamed MK-0822) is an investigational treatment for osteoporosis and bone metastasis.

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Olaflur

Olaflur (INN, or amine fluoride 297) is a fluoride-containing substance that is an ingredient of toothpastes and solutions for the prevention of dental caries.

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Oleclumab

Oleclumab (INN) (MEDI9447) is a human monoclonal antibody designed for the treatment of pancreatic and colorectal cancer.

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Olmutinib

Olmutinib (INN) is an investigational anti-cancer drug.

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Olpadronic acid

Olpadronic acid (INN; salt form olpadronate) is a bisphosphonate.

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Olprinone

Olprinone (INN) is a cardiotonic agent.

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Omacetaxine mepesuccinate

Omacetaxine mepesuccinate (INN, trade names Synribo or Myelostat), formerly named as homoharringtonine or HHT, is a pharmaceutical drug substance that is indicated for treatment of chronic myeloid leukemia (CML).

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Omapatrilat

Omapatrilat (INN, proposed trade name Vanlev) is an experimental antihypertensive agent that was never marketed.

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Omecamtiv mecarbil

Omecamtiv mecarbil (INN), previously referred to as CK-1827452, is a cardiac-specific myosin activator.

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Omega-3 carboxylic acids

Omega-3 carboxylic acids (Epanova) is an FDA approved prescription medication used alongside a low fat and low cholesterol diet that lowers high triglyceride (fat) levels in adults with very high levels.

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Omiloxetine

Omiloxetine (omiloextinum, omiloxetino INN) was a selective serotonin reuptake inhibitor drug candidate that underwent preclinical development by the Spanish pharmaceutical company, Ferrer Internacional, until 2005, when it was abandoned.

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Onapristone

Onapristone (INN) (developmental code names ZK-89299, ZK-299) is a synthetic, steroidal antiprogestogen with additional antiglucocorticoid activity which was developed by Schering and described in 1984 but was never marketed.

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Oportuzumab monatox

Oportuzumab monatox (proposed INN, trade name Vicinium) is an antineoplastic.

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Oritavancin

Oritavancin (INN, also known as LY333328, Orbactiv) is a novel semisynthetic glycopeptide antibiotic for the treatment of serious Gram-positive bacterial infections.

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Ortetamine

Ortetamine (INN), also known as 2-methylamphetamine, is a stimulant drug of the amphetamine class.

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Orticumab

Orticumab (INN) is a human monoclonal antibody that is used as an anti-inflammatory agent and binds to oxLDL.

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Osilodrostat

Osilodrostat (INN, USAN) (developmental code name LCI-699) is an orally active, nonsteroidal corticosteroid biosynthesis inhibitor which is under development by Novartis for the treatment of Cushing's syndrome and adrenocorticotropic hormone hypersecretion (a specific subtype of Cushing's syndrome).

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Otamixaban

Otamixaban (INN) is an experimental injectable anticoagulant direct factor Xa inhibitor that was investigated for the treatment for acute coronary syndrome.

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Oxaflozane

Oxaflozane (INN) (brand name Conflictan) is an antidepressant and anxiolytic drug that was introduced by Solvay in France in 1982 for the treatment of depression but has since been discontinued.

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Oxetacaine

Oxetacaine (INN, also known as oxethazaine) is a potent local anesthetic.

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Oxetorone

Oxetorone (INN), as oxetorone fumarate (USAN) (brand names Nocertone, Oxedix), is a serotonin antagonist, antihistamine, and alpha blocker used as an antimigraine drug.

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Oxifentorex

Oxifentorex (INN) is an amphetamine described as an anorectic which does not appear to have ever been marketed.

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Oxilorphan

Oxilorphan (INN, USAN) (developmental code name L-BC-2605) is an opioid antagonist of the morphinan family that was never marketed.

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Oxipurinol

Oxipurinol (INN, or oxypurinol USAN) is an inhibitor of xanthine oxidase.

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Oxogestone

Oxogestone (INN) is a steroidal progestin related to the 19-norprogesterone derivatives that was synthesized in 1953 and was developed as an injectable hormonal contraceptive in the early 1970s but was never marketed.

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Oxybuprocaine

Oxybuprocaine (INN), also known as benoxinate or BNX, is an ester-type local anesthetic, which is used especially in ophthalmology and otolaryngology.

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Oxycodone/ibuprofen

Oxycodone/ibuprofen (INNs, trade name Combunox) is an oral combination drug formulation of the opioid analgesic oxycodone and the nonsteroidal anti-inflammatory drug (NSAID) ibuprofen that is used in the treatment of chronic and acute pain.

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Ozagrel

Ozagrel (INN) is an antiplatelet agent working as a thromboxane A2 synthesis inhibitor.

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Ozenoxacin

Ozenoxacin (INN; trade names Ozaenex and Xepi) is a quinolone antibiotic being approved for the treatment of impetigo.

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Paclitaxel

Paclitaxel (PTX), sold under the brand name Taxol among others, is a chemotherapy medication used to treat a number of types of cancer.

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Pacritinib

Pacritinib (INN) is a macrocyclic Janus kinase inhibitor that is being developed for the treatment of myelofibrosis.

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Palonosetron

Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

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Pamidronic acid

Pamidronic acid (INN) or pamidronate disodium (USAN), pamidronate disodium pentahydrate (marketed as Aredia by Novartis and as Pamimed by Curacell Biotech), is a nitrogen-containing bisphosphonate used to prevent osteoporosis.

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Pamrevlumab

Pamrevlumab (INN) (FG-3019) is a humanized monoclonal antibody designed for the treatment of idiopathic pulmonary fibrosis and pancreatic cancer.

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Panipenem

Panipenem (INN) is a carbapenem antibiotic used in combination with betamipron.

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Panitumumab

Panitumumab (INN), formerly ABX-EGF, is a fully human monoclonal antibody specific to the epidermal growth factor receptor (also known as EGF receptor, EGFR, ErbB-1 and HER1 in humans).

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Panobacumab

Panobacumab (proposed INN) is a monoclonal antibody designed as an antibacterial against Pseudomonas aeruginosa.

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Panomifene

Panomifene (INN) (former developmental code names GYKI-13504, EGIS-5650) is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group related to tamoxifen that was under development as an antineoplastic agent by Egis Pharmaceuticals and IVAX Drug Research Institute in the 1990s for the treatment of breast cancer but was not marketed.

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Paracetamol

--> Acetanilide was the first aniline derivative serendipitously found to possess analgesic as well as antipyretic properties, and was quickly introduced into medical practice under the name of Antifebrin by A. Cahn and P. Hepp in 1886. But its unacceptable toxic effects, the most alarming being cyanosis due to methemoglobinemia, prompted the search for less toxic aniline derivatives. Harmon Northrop Morse had already synthesised paracetamol at Johns Hopkins University via the reduction of ''p''-nitrophenol with tin in glacial acetic acid in 1877, but it was not until 1887 that clinical pharmacologist Joseph von Mering tried paracetamol on humans. In 1893, von Mering published a paper reporting on the clinical results of paracetamol with phenacetin, another aniline derivative. Von Mering claimed that, unlike phenacetin, paracetamol had a slight tendency to produce methemoglobinemia. Paracetamol was then quickly discarded in favor of phenacetin. The sales of phenacetin established Bayer as a leading pharmaceutical company. Overshadowed in part by aspirin, introduced into medicine by Heinrich Dreser in 1899, phenacetin was popular for many decades, particularly in widely advertised over-the-counter "headache mixtures", usually containing phenacetin, an aminopyrine derivative of aspirin, caffeine, and sometimes a barbiturate. Paracetamol is the active metabolite of phenacetin and acetanilide, both once popular as analgesics and antipyretics in their own right. However, unlike phenacetin, acetanilide and their combinations, paracetamol is not considered carcinogenic at therapeutic doses. Von Mering's claims remained essentially unchallenged for half a century, until two teams of researchers from the United States analyzed the metabolism of acetanilide and paracetamol. In 1947 David Lester and Leon Greenberg found strong evidence that paracetamol was a major metabolite of acetanilide in human blood, and in a subsequent study they reported that large doses of paracetamol given to albino rats did not cause methemoglobinemia. In three papers published in the September 1948 issue of the Journal of Pharmacology and Experimental Therapeutics, Bernard Brodie, Julius Axelrod and Frederick Flinn confirmed using more specific methods that paracetamol was the major metabolite of acetanilide in human blood, and established that it was just as efficacious an analgesic as its precursor. They also suggested that methemoglobinemia is produced in humans mainly by another metabolite, phenylhydroxylamine. A follow-up paper by Brodie and Axelrod in 1949 established that phenacetin was also metabolised to paracetamol. This led to a "rediscovery" of paracetamol. It has been suggested that contamination of paracetamol with 4-aminophenol, the substance von Mering synthesised it from, may be the cause for his spurious findings. Paracetamol was first marketed in the United States in 1950 under the name Triagesic, a combination of paracetamol, aspirin, and caffeine. Reports in 1951 of three users stricken with the blood disease agranulocytosis led to its removal from the marketplace, and it took several years until it became clear that the disease was unconnected. Paracetamol was marketed in 1953 by Sterling-Winthrop Co. as Panadol, available only by prescription, and promoted as preferable to aspirin since it was safe for children and people with ulcers. In 1955, paracetamol was marketed as Children's Tylenol Elixir by McNeil Laboratories. In 1956, 500 mg tablets of paracetamol went on sale in the United Kingdom under the trade name Panadol, produced by Frederick Stearns & Co, a subsidiary of Sterling Drug Inc. In 1963, paracetamol was added to the British Pharmacopoeia, and has gained popularity since then as an analgesic agent with few side-effects and little interaction with other pharmaceutical agents. Concerns about paracetamol's safety delayed its widespread acceptance until the 1970s, but in the 1980s paracetamol sales exceeded those of aspirin in many countries, including the United Kingdom. This was accompanied by the commercial demise of phenacetin, blamed as the cause of analgesic nephropathy and hematological toxicity. In 1988 Sterling Winthrop was acquired by Eastman Kodak which sold the over the counter drug rights to SmithKline Beecham in 1994. Available without a prescription since 1959, it has since become a common household drug. Patents on paracetamol have long expired, and generic versions of the drug are widely available.

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Paracetamol brand names

The analgesic (pain reliever) and antipyretic (fever reducer) paracetamol (INN), also known as acetaminophen (USAN), is sold around the world under a number of different brand names.

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Pardoprunox

Pardoprunox (INN) (code name SLV-308) is an antiparkinsonian drug developed by Solvay for the treatment of Parkinson's disease that reached phase III clinical trials before being discontinued.

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Parsatuzumab

Parsatuzumab (INN) is a humanized monoclonal antibody designed for the treatment of cancer.

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Patritumab

Patritumab (INN) is a human monoclonal antibody designed for the treatment of cancer.

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Pazufloxacin

Pazufloxacin (INN) is a fluoroquinolone antibiotic.

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Peginesatide

Peginesatide (INN/USAN, trade name Omontys, formerly Hematide), developed by Affymax and Takeda, is an erythropoietic agent, a functional analog of erythropoietin.

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Pemirolast

Pemirolast (INN) is a mast cell stabilizer used as an anti-allergic drug therapy.

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Penimepicycline

Penimepicycline (INN, also known as mepicycline penicillinate) is an antibiotic.

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Pentafluranol

Pentafluranol (INN, BAN) (developmental code name BX-430) is a synthetic, nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol that was developed for the treatment of benign prostatic hyperplasia never marketed.

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Pentobarbital

Pentobarbital (INN, AAN, BAN, USAN) or pentobarbitone (former AAN and BAN) is a short-acting barbiturate.

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Pentoxyverine

Pentoxyverine (rINN) or carbetapentane is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold.

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Pentylenetetrazol

Pentylenetetrazol, also known as pentylenetetrazole, metrazol, pentetrazol (INN), pentamethylenetetrazol, Corazol, Cardiazol, deumacard or PTZ, is a drug formerly used as a circulatory and respiratory stimulant.

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Peptide receptor radionuclide therapy

Peptide receptor radionuclide therapy (PRRT) is a type of unsealed source radiotherapy, using a radiopharmaceutical which targets peptide receptors to deliver localised treatment, typically for neuroendocrine tumours (NETs).

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Perafensine

Perafensine (INN) (code name HR-459) is a drug which was investigated as an antidepressant but was never marketed.

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Perakizumab

Perakizumab (INN) is a humanized monoclonal antibody designed for the treatment of arthritis.

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Perflenapent

Perflenapent (INN/USAN), or perfluoropentane (PFP), is a fluorocarbon.

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Perflubron

Perflubron (INN/USAN, or perfluorooctyl bromide; brand name Imagent) is a contrast medium for magnetic resonance imaging, computer tomography and sonography.

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Periciazine

Periciazine (INN), also known as pericyazine (BAN) or propericiazine, is a drug that belongs to the phenothiazine class of typical antipsychotics.

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Pexacerfont

Pexacerfont (INN, previously known as BMS-562,086) is a drug developed by Bristol-Myers Squibb which acts as a CRF1 antagonist.

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Pexastimogene devacirepvec

JX-594 is an oncolytic virus (also known as Pexa-Vec, INN pexastimogene devacirepvec) originally constructed in Dr.

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Phenacemide

Phenacemide (INN, BAN) (brand name Phenurone), also known as phenylacetylurea, is an anticonvulsant of the ureide (acetylurea) class.

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Phenazone

Phenazone (INN and BAN; also known as phenazon, antipyrine (USAN), or analgesine) is an analgesic, a nonsteroidal anti-inflammatory drug (NSAID) and an antipyretic.

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Pheneturide

Pheneturide (INN, BAN) (brand names Benuride, Deturid, Pheneturid, Septotence, Trinuride), also known as phenylethylacetylurea (or ethylphenacemide), is an anticonvulsant of the ureide class.

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Pheniprazine

Pheniprazine (INN; also known as amphethydrazine and amphetamine hydrazide; brand names Catron and Cavodil) is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant in the 1960s.

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Pheniramine

Pheniramine (INN, trade name Avil, among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.

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Phenmetrazine

Phenmetrazine (INN, USAN, BAN) (brand name Preludin, and many others) is a stimulant drug that was previously used as an appetite suppressant, but has since been withdrawn from the market.

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Phenobarbital

Phenobarbital, also known as phenobarbitone or phenobarb, is a medication recommended by the World Health Organization for the treatment of certain types of epilepsy in developing countries.

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Phenylpiracetam

Phenylpiracetam (INN: fonturacetam, brand names Phenotropil Фенотропил, Carphedon), is a phenylated analog of the drug piracetam.

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Picilorex

Picilorex (INN; brand name Roxenan) is an anorectic which is no longer marketed.

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Piketoprofen

Piketoprofen (INN; trade names Calmatel, Picalm) is a nonsteroidal anti-inflammatory drug (NSAID) for topical use in form of a cream.

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Pilsicainide

Pilsicainide (INN) is an antiarrhythmic agent.

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Pimobendan

Pimobendan (INN, or pimobendane; tradenames Vetmedin, Acardi, and Heartmedin) is a veterinary medication.

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Pinatuzumab vedotin

Pinatuzumab vedotin (DCDT2980S, FCU2703) (INN) is a monoclonal antibody designed for the treatment of B-cell malignancies.

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Pinaverium bromide

Pinaverium bromide (INN) is a medication used for functional gastrointestinal disorders.

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Pipamazine

Pipamazine (INN; trade names Mornidine, Mometine, Nausidol) is a drug of the phenothiazine class formerly used as an antiemetic.

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Pipamperone

Pipamperone (INN, USAN, BAN), also known as carpiperone and floropipamide or fluoropipamide, and as floropipamide hydrochloride (JAN), is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia.

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Pipazetate

Pipazetate (INN) (brand names Dipect, Lenopect, Selvigon, Theratuss, Toraxan), or pipazethate (USAN), is a cough suppressant of the phenothiazine class.

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Pipequaline

Pipequaline (INN) (developmental code name PK-8165) is an anxiolytic drug that was never marketed.

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Pirarubicin

Pirarubicin (INN) is an anthracycline drug.

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Piretanide

Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups.

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Piroctone olamine

Piroctone olamine (INN; also known as piroctone ethanolamine; brand name Octopirox) is a compound sometimes used in the treatment of fungal infections.

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Piroxicam

Piroxicam (INN, BAN, USAN, AAN; in some countries it is spelled piroksikam or piroxikam) is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class used to relieve the symptoms of painful, inflammatory conditions like arthritis.

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Pivagabine

Pivagabine (INN; brand name Tonerg), also known as N-pivaloyl-γ-aminobutyric acid or N-pivaloyl-GABA, is an antidepressant and anxiolytic drug which was introduced in Italy in 1997 for the treatment of depressive and maladaptive syndromes.

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Pivenfrine

Pivenfrine (INN), also known as pivalylphenylephrine, is a sympathomimetic and mydriatic agent.

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Pivmecillinam

Pivmecillinam (INN) or amdinocillin pivoxil (USAN, trade names Selexid, Penomax and Coactabs) is an orally active prodrug of mecillinam, an extended-spectrum penicillin antibiotic.

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Pixantrone

Pixantrone (rINN; trade name Pixuvri) is an experimental antineoplastic (anti-cancer) drug, an analogue of mitoxantrone with fewer toxic effects on cardiac tissue.

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Pizotifen

Pizotifen (INN) or pizotyline (USAN), trade name Sandomigran, is a benzocycloheptene-based drug used as a medicine, primarily as a preventative to reduce the frequency of recurrent migraine headaches.

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Plerixafor

Plerixafor (INN and USAN, trade name Mozobil) is an immunostimulant used to mobilize hematopoietic stem cells in cancer patients into the bloodstream.

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Plicamycin

Plicamycin (INN, also known as mithramycin; trade name Mithracin) is an antineoplastic antibiotic produced by Streptomyces plicatus.

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Plozalizumab

Plozalizumab (hu1D9) (INN) is a humanized monoclonal antibody designed for the treatment of diabetic nephropathy and arteriovenous graft patency.

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Polatuzumab vedotin

Polatuzumab vedotin (INN) (DCDS4501A or RG7596) is an antibody-drug conjugate or ADC designed for the treatment of cancer.

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Polycarbophil calcium

Polycarbophil calcium (INN) is a drug used as a stool stabilizer.

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Polyhexanide

Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic.

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Pomalidomide

Pomalidomide (INN; marketed as Pomalyst in the U.S. and Imnovid in the EU and Russia) is a derivative of thalidomide marketed by Celgene.

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Ponazuril

Ponazuril (INN), sold by Merial, Inc.

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Ponesimod

Ponesimod (INN, codenamed ACT-128800) is an experimental drug for the treatment of multiple sclerosis (MS) and psoriasis.

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Potassium canrenoate

Potassium canrenoate (INN, JAN) or canrenoate potassium (USAN) (brand names Venactone, Soldactone), also known as aldadiene kalium, the potassium salt of canrenoic acid, is an aldosterone antagonist of the spirolactone group.

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Pozanicline

Pozanicline (INN, codenamed ABT-089) is a drug developed by Abbott, that has nootropic and neuroprotective effects.

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Pramocaine

Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic discovered at Abbott Laboratories in 1953Schmidt JL, Blockus LE, Richards RK.

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Pranoprofen

Pranoprofen (INN) is a nonsteroidal anti-inflammatory drug (NSAID) used in ophthalmology.

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Primidone

Primidone (INN, BAN, USP) is an anticonvulsant of the barbiturate class.

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Prinaberel

Prinaberel (INN, USAN) (developmental code names ERB-041, WAY-202041) is a synthetic, nonsteroidal, and highly selective agonist of the ERβ subtype of the estrogen receptor.

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Pristinamycin

Pristinamycin (INN), also spelled pristinamycine, is an antibiotic used primarily in the treatment of staphylococcal infections, and to a lesser extent streptococcal infections.

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Profenamine

Profenamine (INN; also known as ethopropazine (BAN); trade names Parsidol, Parsidan, Parkin) is a phenothiazine derivative used as an antiparkinsonian agent that has anticholinergic, antihistamine, and antiadrenergic actions.

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Progabide

Progabide (INN) (trade name Gabrene, Sanofi-Aventis) is an analogue and prodrug of γ-aminobutyric acid (GABA) used in the treatment of epilepsy.

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Propagermanium

Propagermanium (INN), also known by a variety of other names including bis(2-carboxyethylgermanium) sesquioxide and 2-carboxyethylgermasesquioxane, is an organometallic compound of germanium that is sold as an alternative medicine.

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Propantheline bromide

Propantheline bromide (INN) is an antimuscarinic agent used for the treatment of excessive sweating (hyperhidrosis), cramps or spasms of the stomach, intestines (gut) or bladder, and involuntary urination (enuresis).

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Propazepine

Propazepine is a tricyclic antidepressant (TCA).

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Propoxate

Propoxate (INN; R7464) is an anesthetic related to etomidate and metomidate that was never marketed.

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Propoxycaine

Propoxycaine (INN) is a local anesthetic.

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Propyliodone

Propyliodone (INN, trade name Dionosil) is a molecule used as a contrast medium.

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Prostaglandin F2alpha

Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost (INN), is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.

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Prosultiamine

Prosultiamine (INN; also known as thiamine propyl disulfide or TPD; brand name Jubedel) is a disulfide thiamine derivative discovered in garlic in Japan in the 1950s, and is a homolog of allithiamine.

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Proxorphan

Proxorphan (INN), also known as proxorphan tartate (USAN) (developmental code name BL-5572M), is an opioid analgesic and antitussive drug of the morphinan family that was never marketed.

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Proxymetacaine

Proxymetacaine (INN) or proparacaine (USAN) is a topical anesthetic drug of the aminoester group.

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Pseudoephedrine

Pseudoephedrine (PSE) is a sympathomimetic drug of the phenethylamine and amphetamine chemical classes.

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Pyroxamine

Pyroxamine (INN), also known as pyroxamine maleate (USAN) (developmental code names AHR-224, NSC-64540), is an antihistamine and anticholinergic related to diphenylpyraline.

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Quilizumab

Quilizumab (INN) is a humanized monoclonal antibody designed for the treatment of asthma.

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Quinagolide

Quinagolide (INN, BAN; brand name Norprolac) is a selective D2 receptor agonist that is used to reduce elevated levels of prolactin (hyperprolactinemia).

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Quinethazone

Quinethazone (INN, brand name Hydromox) is a thiazide-like diuretic used to treat hypertension.

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Quinisocaine

Quinisocaine (INN) or dimethisoquin (BAN and USAN) is a topical anesthetic used as an antipruritic.

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Racemoramide

Racemoramide (INN, BAN), or simply moramide, is an opioid analgesic and a racemic mixture of the substances dextromoramide (the active component) and levomoramide (which is inactive), two enantiomers of a chiral molecule.

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Radalbuvir

Radalbuvir (INN, also known as GS-9669) is an experimental antiviral drug for the treatment of hepatitis C virus (HCV) infection developed by Gilead Sciences.

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Radequinil

Radequinil (INN; AC-3933) is a cognitive enhancer which acts as a partial inverse agonist of the benzodiazepine site of the GABAA receptor.

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Radezolid

Radezolid (INN, codenamed RX-1741) is a novel oxazolidinone antibiotic being developed by Melinta Therapeutics, Inc.

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Radiopharmaceutical

Radiopharmaceuticals, or medicinal radiocompounds, are a group of pharmaceutical drugs which have radioactivity.

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Radiopharmacology

Radiopharmacology or medicinal radiochemistry is radiochemistry applied to medicine and thus the pharmacology of radiopharmaceuticals (medicinal radiocompounds, that is, pharmaceutical drugs that are radioactive).

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Radotinib

Radotinib (INN; trade name Supect), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of cancer, most notably Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) with resistance or intolerance of other Bcr-Abl tyrosine-kinase inhibitors, such as patients resistant or intolerant to imatinib.

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Ralfinamide

Ralfinamide (INN) (code names NW-1029, FCE-26742A, PNU-0154339E) is a multimodal drug which is under investigation by Newron Pharmaceuticals for the treatment of neuropathic pain and other pain conditions such as post-operative dental pain.

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Ralpancizumab

Ralpancizumab (RN317) (INN) is a monoclonal antibody designed for the treatment of dyslipidemia.

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Ramatroban

Ramatroban (INN) is a thromboxane receptor antagonist.

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Ramoplanin

Ramoplanin (INN) is a glycolipodepsipeptide antibiotic drug derived from strain ATCC 33076 of Actinoplanes.

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Ramosetron

Ramosetron (INN) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting.

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Ranevetmab

Ranevetmab (NV-01) (INN) is a veterinary monoclonal antibody designed for the treatment of pain associated with osteoarthritis in dogs.

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Ranimustine

Ranimustine (INN, marketed under the tradename Cymerin; also known as MCNU) is a nitrosourea alkylating agent approved in Japan for the treatment of chronic myelogenous leukemia and polycythemia vera.

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Raseglurant

Raseglurant (INN) (code name ADX-10059) is a negative allosteric modulator of the mGlu5 receptor and derivative of MPEP which was under development by Addex Therapeutics for the treatment of migraine, gastroesophageal reflux disease, and dental anxiety.

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Ravulizumab

Ravulizumab (ALXN1210) (INN) is a humanized monoclonal antibody designed for the treatment of paroxysmal nocturnal hemaglobinuria and atypical hemolytic uremic syndrome.

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Razobazam

Razobazam (INN) is a drug which is a benzodiazepine derivative.

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Recombinant factor VIIa

Recombinant factor VIIa (rFVIIa) is a form of blood factor VII that has been manufactured via recombinant technology.

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Relamorelin

Relamorelin (INN, USAN) (developmental code names RM-131, BIM-28131, BIM-28163) is a synthetic peptide, centrally penetrant, selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) which is under development by Allergan pharmaceuticals for the treatment of diabetic gastroparesis, chronic idiopathic constipation, and anorexia nervosa.

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Remogliflozin etabonate

Remogliflozin etabonate (INN/USAN) is a proposed drug of the gliflozin class for the treatment of non-alcoholic steatohepatitis ("NASH") and type 2 diabetes.

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Renanolone

Renanolone (INN), or 11-ketopregnanolone, also known as 5β-pregnan-3α-ol-11,20-dione, is a synthetic neuroactive steroid which is described as a general anesthetic but was never introduced for clinical use.

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Repirinast

Repinirast (INN; marketed under the tradename Romet) is an antihistamine.

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Reproterol

Reproterol (INN) is a short-acting β2 adrenoreceptor agonist used in the treatment of asthma.

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Retigabine

Retigabine or ezogabine is an anticonvulsant used as an adjunctive treatment for partial epilepsies in treatment-experienced adult patients.

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Ribavirin

Ribavirin, also known as tribavirin, is an antiviral medication used to treat RSV infection, hepatitis C, and viral hemorrhagic fever.

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Ridinilazole

Ridinilazole (INN, previously known as SMT19969) is a non-absorbable small molecule antibiotic for oral administration to treat ''Clostridium difficile'' infection (CDI).

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Rifampicin

Rifampicin, also known as rifampin, is an antibiotic used to treat several types of bacterial infections, including tuberculosis, leprosy, and Legionnaire's disease.

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Rimantadine

Rimantadine (INN, sold under the trade name Flumadine) is an orally administered antiviral drug used to treat, and in rare cases prevent, influenzavirus A infection.

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Rimiterol

Rimiterol (INN/USAN) is a third-generation short-acting β2 agonist.

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RINN

Rinn or RINN may refer to.

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Riodipine

Riodipine (INN) (brand names Foridon, Ryosidine) is a calcium channel blocker.

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Risedronic acid

Risedronic acid (INN) often used as its sodium salt risedronate sodium (USAN) is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget's disease of bone.

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Ritanserin

Ritanserin (INN, USAN, BAN) is a serotonin receptor antagonist which was never marketed for clinical use but has been used in scientific research.

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Rivoglitazone

Rivoglitazone (INN) is a thiazolidinedione derivative undergoing research for use in the treatment of type 2 diabetes.

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Robatumumab

Robatumumab (proposed INN), also known as SCH 717454 and MK-7454 is a monoclonal antibody and an antineoplastic by Merck and Schering-Plough.

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Roflurane

Roflurane (INN, USAN, code name DA-893) is a halocarbon drug which was investigated as an inhalational anesthetic but was never marketed.

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Rolapitant

Rolapitant (INN, trade name Varubi in the US and Varuby in Europe) is a drug originally developed by Schering-Plough and licensed for clinical development by Tesaro, which acts as a selective NK1 receptor antagonist (antagonist for the NK1 receptor).

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Romiplostim

Romiplostim (rINN, USAN) is a fusion protein analog of thrombopoietin, a hormone that regulates platelet production.

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Ropinirole

Ropinirole (INN; trade names Requip, Repreve, Ronirol, Adartrel) is a dopamine agonist of the non-ergoline class of medications.

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Ropivacaine

Ropivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group.

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Rosmantuzumab

Rosmantuzumab (OMP-131R10) (INN) is a humanized monoclonal antibody designed for the treatment of cancer.

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Rosonabant

Rosonabant (INN; E-6776) is a drug acting as a CB1 receptor antagonist/inverse agonist that was under investigation by Esteve as an appetite suppressant for the treatment of obesity.

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Rosuvastatin

Rosuvastatin (INN), marketed under the tradename Crestor, is a member of the drug class of statins, used in combination with exercise, diet, and weight-loss to treat high cholesterol and related conditions, and to prevent cardiovascular disease.

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Roxibolone

Roxibolone (INN) (developmental code name BR-906), also known as 11β,17β-dihydroxy-17α-methyl-3-oxoandrosta-1,4-diene-2-carboxylic acid, is a steroidal antiglucocorticoid described as an anticholesterolemic (cholesterol-lowering) and anabolic drug which was never marketed.

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RTI-55

RTI(-4229)-55, also called RTI-55 or iometopane, is a phenyltropane-based psychostimulant used in scientific research and in some medical applications.

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Rubitecan

Rubitecan (INN, marketing name Orathecin) is an oral topoisomerase inhibitor, developed by Supergen (now.; a member of the).

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Sacubitril

Sacubitril (INN) is an antihypertensive drug used in combination with valsartan.

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Sacubitrilat

Sacubitrilat (INN; or LBQ657) is the active metabolite of the antihypertensive drug sacubitril, which is used in the treatment of heart failure.

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Salbutamol

Salbutamol, also known as albuterol and marketed as Ventolin among other names, is a medication that opens up the medium and large airways in the lungs.

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Samidorphan

Samidorphan (INN, USAN) (developmental code names ALKS-33, RDC-0313), also known as 3-carboxamido-4-hydroxynaltrexone, is an opioid antagonist that preferentially acts as an antagonist of the μ-opioid receptor (MOR).

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Sarafloxacin

Sarafloxacin (INN) is a quinolone antibiotic drug, which was removed from clinical use by its manufacturer Abbott Laboratories from April 30, 2001.

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Saroglitazar

Saroglitazar (INN, trade name Lipaglyn) is a drug for the treatment of type 2 diabetes mellitus and dyslipidemia.

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Satavaptan

Satavaptan (INN; developmental code name SR121463, former tentative brand name Aquilda) is a vasopressin-2 receptor antagonist which was investigation by Sanofi-Aventis and was under development for the treatment of hyponatremia.

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Satraplatin

Satraplatin (INN, codenamed JM216) is a platinum-based antineoplastic agent that is under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy.

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Scleroderma

Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs.

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Selepressin

Selepressin (INN) (code name FE-202158), also known as vasopressin) is a potent, highly selective, short-acting peptide full agonist of the vasopressin 1A receptor and analog of vasopressin which is under development by Ferring Pharmaceuticals for the treatment of vasodilatory hypotension in septic shock.

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Selurampanel

Selurampanel (INN, code name BGG492) is a drug closely related to the quinoxalinedione series which acts as a competitive antagonist of the AMPA and kainate receptors and, as of 2015, is being investigated in clinical trials by Novartis for the treatment of epilepsy.

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Semapimod

Semapimod (INN), formerly known as CNI-1493, is an investigational new drug which has anti-inflammatory, anti-cytokine, immunomodulatory, antiviral and antimalarial properties.

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Semuloparin sodium

Semuloparin (INN, USAN) is an experimental antithrombotic being developed by Sanofi-Aventis and belongs to the group of low molecular weight heparins (LMWH).

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Seneka Bibile

Senaka Bibile (Sinhala:සේනක බිබිලේ) (13 February 1920 – 29 September 1977) was a Sri Lankan pharmacologist.

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Sergliflozin etabonate

Sergliflozin etabonate (INN/USAN, codenamed GW869682X) is an investigational anti-diabetic drug being developed by GlaxoSmithKline.

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Seribantumab

Seribantumab (MM-121) (INN) is a monoclonal antibody designed for the treatment of cancer.

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Serlopitant

Serlopitant (INN, codenamed VPD-737) is a drug which acts as an NK1 receptor antagonist.

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Setipiprant

Setipiprant (INN) (developmental code names ACT-129968, KYTH-105) is an investigational drug developed for the treatment of asthma and scalp hair loss.

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Sevelamer

Sevelamer (rINN) is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease.

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Silibinin

Silibinin (INN), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin, and others.

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Silmitasertib

Silmitasertib (INN), codenamed CX-4945, is a small-molecule inhibitor of protein kinase CK2 (casein kinase II), a constitutively active serine/threonine-specific protein kinase that is overexpressed in several types of tumors.

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Silperisone

Silperisone (INN) is a muscle relaxant.

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Siltuximab

Siltuximab (INN, trade name Sylvant; also known as CNTO 328, anti-IL-6 chimeric monoclonal antibody or cCLB8) is a chimeric (made from human and mouse proteins) monoclonal antibody.

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Simeticone

Simeticone (INN), also known as simethicone (USAN), is an anti-foaming agent used to reduce bloating, discomfort or pain caused by excessive gas.

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Simtuzumab

Simtuzumab (INN; formerly GS 6624) is a humanized monoclonal antibody designed for the treatment of fibrosis.

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Siponimod

Siponimod (INN, code name BAF312) is a selective sphingosine-1-phosphate receptor modulator for oral use that is an investigational drug for multiple sclerosis (MS).

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Sirukumab

Sirukumab (INN, USAN) (developmental code name CNTO-136) is a human monoclonal antibody designed for the treatment of rheumatoid arthritis.

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Sitafloxacin

Sitafloxacin (INN; also called DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer.

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Sitagliptin

Sitagliptin (INN;, previously identified as MK-0431 and marketed as the phosphate salt under the trade name Januvia) is an oral antihyperglycemic (antidiabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class.

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Sivelestat

Sivelestat (INN, research name ONO 5046, marketed as Elaspol) is an inhibitor of human neutrophil elastase.

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Sivifene

Sivifene (INN, USAN; developmental code name A-007) is a small-molecule antineoplastic agent and immunomodulator that was under development in the 2000s by Tigris Pharmaceuticals (now Kirax Corporation) as a topical treatment for cutaneous cancer metastases.

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Sodium acetrizoate

Sodium acetrizoate (rINN, trade names Urokon, Triurol and Salpix), the sodium salt of acetrizoic acid, is a high-osmolality, water-soluble, iodine-based radiographic contrast medium no longer in clinical use.

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Sodium apolate

Sodium apolate (INN) or lyapolate sodium (USAN) is a vasoprotective.

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Sodium aurothiomalate

Sodium aurothiomalate (INN, known in the United States as gold sodium thiomalate) is a gold compound that is used for its immunosuppressive anti-rheumatic effects.

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Sodium dichloroisocyanurate

Sodium dichloroisocyanurate (INN: sodium troclosene, troclosenum natricum or NaDCC or SDIC) is a chemical compound widely used as a cleansing agent and disinfectant.

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Sodium oxybate

Sodium oxybate is a prescription medication used to treat two symptoms of narcolepsy: sudden muscle weakness and excessive daytime sleepiness.

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Sodium picosulfate

Sodium picosulfate (INN, also known as sodium picosulphate) is a contact stimulant laxative used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery.

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Sofalcone

Sofalcone (INN) is an oral gastrointestinal medication used in Japan.

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Sofituzumab vedotin

Sofituzumab vedotin (DMUC5754A) (INN) is a monoclonal antibody designed for the treatment of ovarian cancer.

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Solanezumab

Solanezumab (proposed INN, LY2062430) is a monoclonal antibody being investigated by Eli Lilly as a neuroprotector for patients with Alzheimer's disease.

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Solifenacin

Solifenacin (INN, trade name Vesicare) is a medicine of the antimuscarinic class and was developed for treating contraction of overactive bladder with associated problems such as increased urination frequency and urge incontinence.

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Solitomab

Solitomab (INN) (MT110) is an artificial bispecific monoclonal antibody that is being investigated as an anti-cancer drug.

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Sonidegib

Sonidegib (INN), also known as LDE225 and marketed as Odomzo, is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) being developed as an anticancer agent by Novartis.

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Sorbinil

Sorbinil (INN) is an aldose reductase inhibitor being investigated for treatment of diabetic complications including neuropathy and retinopathy.

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Sorivudine

Sorivudine (INN), is a nucleoside analogue antiviral drug, marketed under trade names such as Usevir (Nippon Shoji, Eisai) and Brovavir (BMS).

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Spirorenone

Spirorenone (INN) (developmental code name ZK-35973) is a steroidal antimineralocorticoid of the spirolactone group that was never marketed.

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Spiroxasone

Spiroxasone (INN, USAN) is a synthetic, steroidal antimineralocorticoid of the spirolactone group which was developed as a diuretic and antihypertensive agent but was never marketed.

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Sprifermin

Sprifermin (INN) (developmental code name AS-902330), also known as recombinant human fibroblast growth factor 18 (rhFGF18), is a recombinant form of human fibroblast growth factor 18 (FGF18)http://www.who.int/medicines/publications/druginformation/innlists/INNprepub105.pdf which is under development by Merck and Nordic Bioscience for the treatment of osteoarthritis.

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Sri Lanka National Pharmaceuticals Policy

The Sri Lanka National Pharmaceuticals Policy was established in the 1970s following the submission of a report by Dr S.A. Wickremasinghe and Prof.

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Stercuronium iodide

Stercuronium iodide (INN, USAN) (developmental code names MYC-1080, MYSC-1080) is an aminosteroid neuromuscular blocking agent which was never marketed.

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Stimulant

Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and invigorating, or drugs that have sympathomimetic effects.

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Streptozotocin

Streptozotocin or streptozocin (INN, USP) (STZ) is a naturally occurring alkylating antineoplastic agent that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals.

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Sucroferric oxyhydroxide

Sucroferric oxyhydroxide (INN; trade name Velphoro, by Vifor Fresenius Medical Care Renal Pharma) is a non-calcium, iron-based phosphate binder used for the control of serum phosphorus levels in adult patients with chronic kidney disease (CKD) on haemodialysis (HD) or peritoneal dialysis (PD).

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Sufotidine

Sufotidine (INN, USAN, codenamed AH25352) is a long-acting competitive H2 receptor antagonist which was under development as an antiulcerant by Glaxo (now GlaxoSmithKline).

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Sulbenicillin

Sulbenicillin (INN) is a penicillin antibiotic.

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Sulfafurazole

Sulfafurazole (INN, also known as sulfisoxazole) is a sulfonamide antibacterial with an oxazole substituent.

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Sulfalene

Sulfalene (INN, USAN) or sulfametopyrazine (BAN) is a long-acting sulfonamide antibacterial used for the treatment of chronic bronchitis, urinary tract infections and malaria.

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Sulfamazone

Sulfamazone (INN) is a sulfonamide antibiotic with antipyretic properties.

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Sulfametoxydiazine

Sulfametoxydiazine (INN) or sulfamethoxydiazine (USAN: sulfameter) is a long-acting sulfonamide antibacterial.

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Sulfametrole

Sulfametrole (INN) is a sulfonamide antibacterial.

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Sulfapyridine

Sulfapyridine (INN; also known as sulphapyridine) is a sulfonamide antibacterial medication.

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Sulfiram

Sulfiram (INN) or monosulfiram, trade name Tetmosol, is an ectoparasiticide used in the treatment and prevention of scabies.

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Sulfisomidine

Sulfisomidine (INN), also known as sulphasomidine (BAN until 2003), sulfamethin and sulfaisodimidine, is a sulfonamide antibacterial.

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Suplatast tosilate

Suplatast tosilate (INN) is a Th2 cytokine inhibitor which is used as an antiallergic drug.

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Suptavumab

Suptavumab (REGN2222) (INN) is a humanized monoclonal antibody designed for the prevention of medically attended lower respiratory tract disease due to respiratory syncytial virus.

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Suvratoxumab

Suvratoxumab (INN) (MEDI4893) is a human monoclonal antibody designed for the prevention of nosocomial pneumonia caused by Staphylococcus aureus.

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Tabimorelin

Tabimorelin (INN) (developmental code name NN-703) is a drug which acts as a potent, orally-active agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and growth hormone secretagogue, mimicking the effects of the endogenous peptide agonist ghrelin as a stimulator of growth hormone (GH) release.

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Tadalafil

Tadalafil (INN) is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction (ED) under the name Cialis, and under the name Adcirca for the treatment of pulmonary arterial hypertension.

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Talampanel

Talampanel (INN) (code names GYKI 537773, LY300164) is a drug which has been investigated for the treatment of epilepsy, malignant gliomas and amyotrophic lateral sclerosis (ALS).

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Talaporfin

Talaporfin (INN, also known as aspartyl chlorin, mono-L-aspartyl chlorin e6, NPe6, or LS11) is a photosensitizer used in photodynamic therapy (PDT).

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Taleranol

Taleranol (INN, USAN) (developmental code name P-1560), or teranol, also known as β-zearalanol, is a synthetic, nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp which was never marketed.

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Tamtuvetmab

Tamtuvetmab (AT-005) (INN, trade name Tactress) is a veterinary monoclonal antibody.

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Tanaproget

Tanaproget (INN; developmental code names NSP-989, WAY-166989) is an investigational nonsteroidal progestin.

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Tanezumab

Tanezumab (INN, codenamed RN624) is a monoclonal antibody against nerve growth factor.

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Taribavirin

Taribavirin (rINN; also known as viramidine, codenamed ICN 3142) is an antiviral drug in Phase III human trials, but not yet approved for pharmaceutical use. It is a prodrug of ribavirin, active against a number of DNA and RNA viruses. Taribavirin has better liver-targeting than ribavirin, and has a shorter life in the body due to less penetration and storage in red blood cells. It is expected eventually to be the drug of choice for viral hepatitis syndromes in which ribavirin is active. These include hepatitis C and perhaps also hepatitis B and yellow fever.

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Tavilermide

Tavilermide (INN) (developmental code name MIM-D3) is a selective, small-molecule partial agonist of TrkA, or a nerve growth factor (NGF) mimetic.

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Tavolimab

Tavolimab (MEDI0562, formerly tavolixizumab) (INN) is a chimeric/humanized monoclonal antibody designed for the treatment of cancer.

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Taxane

Taxanes are a class of diterpenes.

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Tecemotide

Tecemotide (INN; emepepimut-S (USAN); formerly known as BLP25 or EMD 531444) is a synthetic lipopeptide that is used as antigen in an investigational therapeutic cancer vaccine (formerly known as Stimuvax, L-BLP25, BLP25 liposomal vaccine or BLP25 liposome vaccine).

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Technetium (99mTc) pintumomab

Technetium (99mTc) pintumomab (INN) is a mouse monoclonal antibody for the imaging of adenocarcinoma.

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Technetium (99mTc) sestamibi

Technetium (99mTc) sestamibi (INN) (commonly sestamibi; USP: technetium Tc 99m sestamibi; trade name Cardiolite) is a pharmaceutical agent used in nuclear medicine imaging.

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Teflurane

Teflurane (INN, USAN, code name Abbott 16900) is a halocarbon drug which was investigated as an inhalational anesthetic but was never marketed.

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Tegafur

Tegafur (INN, BAN, USAN) is a chemotherapeutic prodrug of 5-fluorouracil (5-FU) used in the treatment of cancers.

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Telcagepant

Telcagepant (INN) (code name MK-0974) is a calcitonin gene-related peptide receptor antagonist which was an investigational drug for the acute treatment and prevention of migraine, developed by Merck & Co..

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Telmisartan

Telmisartan (INN) is an angiotensin II receptor antagonist (angiotensin receptor blocker, ARB) used in the management of hypertension.

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Telmisartan/hydrochlorothiazide

Telmisartan/hydrochlorothiazide (INNs, trade names MicardisPlus or Micardis HCT) is an antihypertensive drug combination of an angiotensin II receptor antagonist with hydrochlorothiazide, the most common diuretic to be combined with other blood pressure lowering substances.

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Temoporfin

Temoporfin (INN) is a photosensitizer (based on chlorin) used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck.

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Teneligliptin

Teneligliptin (INN; trade name Tenelia) is a pharmaceutical drug for the treatment of type 2 diabetes mellitus.

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Tenofovir alafenamide

Tenofovir alafenamide (INN/USAN; trade name Vemlidy) is a nucleotide reverse transcriptase inhibitor and a prodrug of tenofovir. It was developed by Gilead Sciences for use in the treatment of HIV infection and chronic hepatitis B, and is applied in the form of tenofovir alafenamide fumarate (TAF). Closely related to the commonly used reverse-transcriptase inhibitor tenofovir disoproxil fumarate (TDF), TAF has greater antiviral activity and better distribution into lymphoid tissues than that agent. Gilead was awarded FDA approval in November 2016 for the drug Vemlidy. Gilead announced a phase 3 clinical trial evaluating a single-tablet regimen combining tenofovir alafenamide with cobicistat, emtricitabine and elvitegravir and developed a coformulation of the drug with cobicistat, emtricitabine and the protease inhibitor darunavir. In a 48-week study comparing elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil (trade name Stribild) to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (trade name Genvoya), the results showed the newer drug to be noninferior to the established agent, but at much lower dosages and with lower incidence of adverse side effects such as impaired kidney function. The FDA approved the TAF-based treatment regimen for treatment of HIV-1 in November 2015. Genvoya is the first TAF-based regimen to receive approval.

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Terbogrel

Terbogrel (INN) blocks thromboxanes and is expected to be useful in treating the vasoconstricting and platelet-aggregating action of this compound.

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Terfluranol

Terfluranol (INN, BAN) (developmental code name BX-428) is a synthetic, nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol that was developed for the treatment of breast cancer but was never marketed.

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Terguride

Terguride (INN), also known as trans-dihydrolisuride, is a serotonin receptor antagonist and dopamine receptor agonist of the ergoline family.

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Tert-Butylamine

tert-Butylamine is an organic chemical compound with the formula (CH3)3CNH2.

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Tesamorelin

Tesamorelin (INN) (trade name Egrifta) is a synthetic form of growth-hormone-releasing hormone (GHRH) which is used in the treatment of HIV-associated lipodystrophy.

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Tesmilifene

Tesmilifene (INN; developmental code names YMB-1002, BMS-217380-01), also known as N,N-diethyl-2-(4-phenylmethyl)ethanamine (DPPE), is a small-molecule antineoplastic drug and chemopotentiator that was under development by YM BioSciences for the treatment of breast cancer in the 2000s but was never marketed.

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Testosterone ketolaurate

Testosterone ketolaurate (INN, USAN) (brand names Androdurin, Testosid-Depot), or testosterone caprinoylacetate, is an androgen and anabolic steroid and a testosterone ester.

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Tetrabarbital

Tetrabarbital (INN; Butysal, Butysedal, Tetramal) is a barbiturate derivative used as a hypnotic.

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Tetroxoprim

Tetroxoprim (INN) is a derivative of trimethoprim.

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Tetryzoline

Tetryzoline (INN; also known as tetrahydrozoline), a derivative of imidazoline, is found in over-the-counter eye drops and nasal sprays.

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Tezampanel

Tezampanel (INN, USAN) (code names LY-293,558, NGX-424) is a drug originally developed by Eli Lilly which acts as a competitive antagonist of the AMPA and kainate subtypes of the ionotropic glutamate receptor family, with selectivity for the GluR5 subtype of the kainate receptor.

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Tezepelumab

Tezepelumab (MEDI9929, AMG 157) (INN) is a human monoclonal antibody designed for the treatment of asthma and atopic dermatitis.

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Thebacon

Thebacon (INN; pronounced), or dihydrocodeinone enol acetate, is a semisynthetic opioid that is similar to hydrocodone and is most commonly synthesised from thebaine.

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Theodrenaline

Theodrenaline (INN), also known as noradrenalinoethyltheophylline, is a chemical linkage of norepinephrine (noradrenaline) and theophylline used as a cardiac stimulant.

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Thiazinamium metilsulfate

Thiazinamium metilsulfate (INN) or thiazinam is an antihistamine.

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Thioacetazone

Thioacetazone (INN, BAN), also known as amithiozone (USAN), is an oral antibiotic which is used in the treatment of tuberculosis.

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Thiomersal

Thiomersal (INN), or thimerosal (USAN, JAN), is an organomercury compound.

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Thiotepa

Thiotepa (INN, chemical name: N,N′,N′′-triethylenethiophosphoramide) is an alkylating agent used to treat cancer.

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Thiotetrabarbital

Thiotetrabarbital (INN; Thionarcex) is a drug which is a short-acting barbiturate derivative that is used as an anesthetic.

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Thyroid-stimulating hormone

Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, TSH, or hTSH for human TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3) which stimulates the metabolism of almost every tissue in the body.

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Thyrotropin-releasing hormone

Thyrotropin-releasing hormone (TRH), also called thyrotropin-releasing factor (TRF) or thyroliberin, is a releasing hormone, produced by the hypothalamus, that stimulates the release of thyrotropin (thyroid-stimulating hormone or TSH) and prolactin from the anterior pituitary.

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Tiabendazole

Tiabendazole (INN, BAN), thiabendazole (AAN, USAN), TBZ (and the trade names Mintezol, Tresaderm, and Arbotect) is a fungicide and parasiticide.

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Tiamenidine

Tiamenidine (BAN, USAN, INN, also known as thiamenidine, Hoe 440) is a imidazoline compound that shares many of the pharmacological properties of clonidine.

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Tibulizumab

Tibulizumab (LY 3090106) (INN) is a humanized monoclonal antibody designed for the treatment of autoimmune diseases.

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Tienilic acid

Tienilic acid (INN and BAN) or ticrynafen (USAN) is a loop diuretic drug with uric acid-lowering (uricosuric) action, formerly marketed for the treatment of hypertension.

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Tigestol

Tigestol (INN, USAN), also known as 17α-ethynylestr-5(10)-en-17β-ol, is a steroidal progestin of the 19-nortestosterone group that was developed by Organon in the 1960s but was never marketed.

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Tilapertin

Tilapertin (INN) is a drug which is described as an antipsychotic.

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Tilisolol

Tilisolol (INN, trade name Selecal) is a beta blocker.

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Tiludronic acid

Tiludronic acid (INN; also known as tiludronate) is a bisphosphonate used for treatment of Paget's disease of bone (osteitis deformans) in human medicine.

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Timepidium bromide

Timepidium bromide (INN) is an anticholinergic.

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Tinabinol

Tinabinol (INN; SP-119) is a synthetic cannabinoid drug and analogue of dronabinol which was patented as an antihypertensive but was never marketed.

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Tioguanine

Tioguanine, also known as thioguanine or 6-thioguanine (6-TG) is a medication used to treat acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), and chronic myeloid leukemia (CML).

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Tiomesterone

Tiomesterone (INN, JAN) (brand names Emdabol, Embadol, Emdabolin, Protabol; former developmental code name StA 307), or thiomesterone (BAN), also known as 1α,7α-bis(acetylthio)-17α-methylandrost-4-en-17β-ol-3-one, is a synthetic, orally active anabolic-androgenic steroid (AAS) and a 17α-alkylated derivative of testosterone.

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Tioxolone

Tioxolone (INN, also spelled thioxolone) is an anti-acne preparation.

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Tipepidine

Tipepidine (INN) (brand names Asverin, Antupex, Asvelik, Asvex, Bitiodin, Cofdenin A, Hustel, Nodal, Sotal), also known as tipepidine hibenzate (JAN), is a synthetic, non-opioid antitussive and expectorant of the thiambutene class.

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Tipifarnib

Tipifarnib (INN, proposed trade name Zarnestra) is a farnesyltransferase inhibitor that is being investigated in patients 65 years of age and older with newly diagnosed acute myeloid leukemia (AML).

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Tirofiban

Tirofiban (INN, trade name Aggrastat) is an antiplatelet drug.

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Tiropramide

Tiropramide (INN) is an antispasmodic.

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Tobramycin/dexamethasone

Tobramycin/dexamethasone (INNs, trade name Tobradex, Tobrason in Jordan) is a prescription medication in the form of eye drops and eye ointment, marketed by Alcon.

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Toceranib

Toceranib is a receptor tyrosine kinase inhibitor and is used in the treatment of canine mast cell tumor also called mastocytoma.

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Tocolytic

Tocolytics (also called anti-contraction medications or labor suppressants) are medications used to suppress premature labor (from the Greek tokos, childbirth, and lytic, capable of dissolving).

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Tofacitinib

Tofacitinib, sold under the brand Xeljanz among others, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.

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Tofogliflozin

Tofogliflozin (INN, USAN, codenamed CSG452) is an experimental drug for the treatment of diabetes mellitus and is being developed by Chugai Pharma in collaboration with Kowa and Sanofi.

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Tolciclate

Tolciclate (INN) is an antifungal medication.

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Tolgabide

Tolgabide INN (SL-81.0142) is a drug which was patented by Synthélabo as an anticonvulsant but was never marketed.

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Tolnaftate

Tolnaftate (INN) is a synthetic thiocarbamate used as an anti-fungal agent that may be sold without medical prescription in most jurisdictions.

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Tolonium chloride

Tolonium chloride (INN, also known as toluidine blue or TBO) is a blue cationic (basic) dye used in histology and sometimes clinically.

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Tolpiprazole

Tolpiprazole (INN, BAN) (developmental code name H-4170) is an anxiolytic drug of the phenylpiperazine group that was never marketed.

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Tolrestat

Tolrestat (INN) (AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications.

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Tolvaptan

Tolvaptan (INN, trade names Samsca and Jinarc) is an aquaretic drug that functions as a selective, competitive vasopressin receptor 2 antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).

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Topiroxostat

Topiroxostat (INN; trade names Topiloric, Uriadec) is a drug for the treatment of gout and hyperuricemia.

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Toripristone

Toripristone (INN) (developmental code name RU-40555) is a synthetic, steroidal antiglucocorticoid as well as antiprogestogen which was never marketed.

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Tranilast

Tranilast (INN, brand name Rizaben) is an antiallergic drug.

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Trazium

Trazium (EGYT-3,615) is an antidepressant drug which was never marketed.

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Trepipam

Trepipam (INN) is a dopamine receptor agonist of the benzazepine group that was never marketed.

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Trevogrumab

Trevogrumab (INN) (REGN1033) is a human monoclonal antibody designed for the treatment of muscle atrophy due to orthopedic disuse and sarcopenia.

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Trichlormethiazide

Trichlormethiazide (INN, currently being sold under the brand names of Achletin, Diu-Hydrin and Triflumen) is a diuretic with properties similar to those of hydrochlorothiazide.

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Triethylenetetramine

Triethylenetetramine, abbreviated TETA and trien and also called trientine (INN), is an organic compound with the formula 2.

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Trimedoxime bromide

Trimedoxime bromide (INN), also known as dipyroxime or TMB-4, is an oxime used in the treatment of organophosphate poisoning.

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Trimetaphan camsilate

Trimetaphan camsilate (INN) or trimethaphan camsylate (USAN), trade name Arfonad, is a drug that counteracts cholinergic transmission at the ganglion type of nicotinic receptors of the autonomic ganglia and therefore blocks both the sympathetic nervous system and the parasympathetic nervous system.

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Trimethoprim/polymyxin

The drug combination trimethoprim/polymyxin (INNs, trade name Polytrim) is an antimicrobial solution for topical ophthalmic use in the treatment of acute bacterial conjunctivitis and blepharoconjunctivitis.

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Trioxifene

Trioxifene (INN) (developmental code name LY-133,314), or as the salt trioxifene mesylate (USAN), is a selective estrogen receptor modulator (SERM) with competitive binding activity against estradiol for the ERα and antagonistic activity against ERα-mediated gene expression, that was under preclinical and clinical development by Eli Lilly and Company for breast cancer and prostate cancer, but was abandoned.

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Tripamide

Tripamide (INN) is a diuretic.

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Triparanol

Triparanol (INN, BAN) (brand and developmental code names MER/29, as well as many other brand names), patented in 1959 and introduced in the United States in 1960, was the first synthetic cholesterol-lowering drug.

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Triplatin tetranitrate

Triplatin tetranitrate (rINN; also known as BBR3464) is a platinum-based cytotoxic drug that underwent clinical trials for the treatment of human cancer.

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Trofosfamide

Trofosfamide (INN) is a nitrogen mustard alkylating agent.

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Tropanserin

Tropanserin (INN; MDL-72,422) is a drug which acts as a potent and selective 5-HT3 receptor antagonist.

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Tropisetron

Tropisetron (INN) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia.

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Trospium chloride

Trospium chloride (INN) is used to treat overactive bladder.

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Tulobuterol

Tulobuterol (INN) is a long-acting beta2-adrenergic receptor agonist, marketed in Japan as a transdermal patch under the name Hokunalin tape (ホクナリンテープ).

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Tumor necrosis factor alpha

Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.

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Tybamate

Tybamate (INN; Solacen, Tybatran, Effisax) is an anxiolytic of the carbamate family.

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Ubenimex

Ubenimex (INN), also known more commonly as bestatin, is a competitive, reversible protease inhibitor.

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Ufenamate

Ufenamate (INN) is a topical analgesic.

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Ulimorelin

Ulimorelin (INN, USAN) (developmental code name TZP-101) is a drug with a modified cyclic peptide structure which acts as a selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR-1a).

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Ulobetasol

Ulobetasol (INN) or halobetasol (USAN) is a corticosteroid used to treat psoriasis.

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Ulocuplumab

Ulocuplumab (MDX-1338) (INN) is a monoclonal antibody designed for the treatment of hematologic malignancies.

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Umirolimus

Umirolimus (INN/USAN), is a macrocyclic lactone, a highly lipophilic derivative of sirolimus, an immunosuppressant.

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United States Adopted Name

United States Adopted Names are unique nonproprietary names assigned to pharmaceuticals marketed in the United States.

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Unoprostone

Unoprostone (INN) is a prostaglandin analogue.

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Uramustine

Uramustine (INN) or uracil mustard is a chemotherapy drug which belongs to the class of alkylating agents.

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Uridine triacetate

Uridine triacetate (INN), formerly known as vistonuridine, is an orally active tri-acetylated prodrug of uridine used.

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Ursodeoxycholic acid

Ursodeoxycholic acid (INN, BAN and AAN), also known as ursodiol (USAN) and the abbreviation UDCA, from the root-word for bear urso, as bear bile contains the substance, is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria.

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Vaborbactam

Vaborbactam (INN) is a non-β-lactam β-lactamase inhibitor discovered by Rempex Pharmaceuticals, a subsidiary of The Medicines Company.

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Valbenazine

Valbenazine, sold under the trade name Ingrezza, is a medication used to treat tardive dyskinesia.

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Valnoctamide

Valnoctamide (INN, USAN) has been used in France as a sedative-hypnotic since 1964.

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Valperinol

Valperinol (INN; GA 30-905) is a drug which acts as a calcium channel blocker.

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Valsartan/hydrochlorothiazide

Valsartan/hydrochlorothiazide (INNs, trade name Co-vasotec) is an antihypertensive drug combination of an angiotensin II receptor antagonist with hydrochlorothiazide, the most common diuretic to be combined with other blood pressure lowering substances.

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Vandetanib

Vandetanib (INN, trade name Caprelsa) is an anti-cancer drug that is used for the treatment of certain tumours of the thyroid gland.

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Vandortuzumab vedotin

Vandortuzumab vedotin (RG7450) (INN) is a humanized monoclonal antibody designed for the treatment of cancer.

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Vanucizumab

Vanucizumab (RG7221) (INN) is an experimental humanized monoclonal antibody designed for the treatment of cancer.

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Vardenafil

Vardenafil (INN) is a PDE5 inhibitor used for treating erectile dysfunction that is sold under the trade names Levitra (Bayer AG, GSK, and SP), Staxyn in India, and Vivanza in Italy.

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Varlilumab

Varlilumab (CDX-1127) (INN) is a monoclonal antibody designed for immunotherapy for solid tumors and hematologic malignancies.

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Vatalanib

Vatalanib (INN, codenamed PTK787 or PTK/ZK) is a small molecule protein kinase inhibitor that inhibits angiogenesis.

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Vedaclidine

Vedaclidine (INN, codenamed LY-297,802, NNC 11-1053) is a novel analgesic drug which acts as a mixed agonist–antagonist at muscarinic acetylcholine receptors, being a potent and selective agonist for the M1 and M4 subtypes, yet an antagonist at the M2, M3 and M5 subtypes.

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Velusetrag

Velusetrag (INN, USAN; previously known as TD-5108) is an experimental drug candidate for the treatment of gastric neuromuscular disorders including gastroparesis, and lower gastrointestinal motility disorders including chronic idiopathic constipation and irritable bowel syndrome.

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Vemurafenib

Vemurafenib (INN, marketed as Zelboraf) is a B-Raf enzyme inhibitor developed by Plexxikon (now part of Daiichi-Sankyo) and Genentech for the treatment of late-stage melanoma.

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Venetoclax

Venetoclax (INN, trade name Venclexta in the US and Venclyxto in Europe) is a small molecule oral drug that treats chronic lymphocytic leukemia (CLL) in those with a specific chromosomal abnormality.

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Vernakalant

Vernakalant (INN; codenamed RSD1235, proposed tradenames Kynapid and Brinavess) is an investigational drug under regulatory review for the acute conversion of atrial fibrillation.

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Vesnarinone

Vesnarinone (INN) is a cardiotonic agent.

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Vestipitant

Vestipitant (INN) is a drug developed by GlaxoSmithKline which acts as a selective antagonist for the NK1 receptor.

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Vilanterol

Vilanterol (INN, USAN) is an ultra-long-acting β2 adrenoreceptor agonist (ultra-LABA), which was approved in May 2013 in combination with fluticasone furoate for sale as Breo Ellipta by GlaxoSmithKline for the treatment of chronic obstructive pulmonary disease (COPD).

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Vilaprisan

Vilaprisan (INN, USAN) (developmental code name BAY-1002670) is a synthetic, steroidal selective progesterone receptor modulator (SPRM) which is under development by Bayer HealthCare Pharmaceuticals for the treatment of endometriosis and uterine fibroids.

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Vinflunine

Vinflunine (INN, trade name Javlor) is a novel fluorinated ''vinca'' alkaloid derivative undergoing research for the treatment of bladder cancer.

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Viqualine

Viqualine (INN) (developmental code name PK-5078) is an antidepressant and anxiolytic drug that was never marketed.

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Vobarilizumab

Vobarilizumab (ALX0061) (INN) is a humanized monoclonal antibody designed for the treatment of inflammatory autoimmune diseases.

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Voglibose

Voglibose (INN and USAN, trade name Voglib, marketed by Mascot Health Series) is an alpha-glucosidase inhibitor used for lowering post-prandial blood glucose levels in people with diabetes mellitus.

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Volanesorsen

Volanesorsen (INN, codenamed ISIS 304801, previously known as ISIS-APOCIIIRx) is a triglyceride-reducing drug.

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Volinanserin

Volinanserin (INN) (developmental code name MDL-100,907) is a highly selective 5-HT2A receptor antagonist that is frequently used in scientific research to investigate the function of the 5-HT2A receptor.

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Volixibat

Volixibat (INN; development code SHP626) is a medication under development as a possible treatment for nonalcoholic steatohepatitis (NASH), the most severe form of non-alcoholic fatty liver disease (NAFLD).

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Vorinostat

Vorinostat (rINN) also known as suberanilohydroxamic acid (suberoyl+anilide+hydroxamic acid abbreviated as SAHA) is a member of a larger class of compounds that inhibit histone deacetylases (HDAC).

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Vosoritide

Vosoritide (INN, codenamed BMN-111) is an experimental drug for the treatment of achondroplasia, the most common cause of dwarfism.

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Xantocillin

Xantocillin (INN), also known as xanthocillin X or ophthocillin, was the first reported natural product found to contain the isocyanide functional group.

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Xorphanol

Xorphanol (INN) (developmental code name TR-5379 or TR-5379M), also known as xorphanol mesylate (USAN), is an opioid analgesic of the morphinan family that was never marketed.

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Zafuleptine

Zafuleptine (INN) (proposed brand name Thymeon) is an antidepressant developed in the mid-1970s which, despite apparently having a chosen brand name, was never marketed.

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Zatuximab

Zatuximab (INN) is a chimeric monoclonal antibody designed for the treatment of cancer.

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Zenazocine

Zenazocine (INN; WIN-42,964) is an opioid analgesic of the benzomorphan family which made it to phase II clinical trials before development was ultimately halted and it was never marketed.

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Zibotentan

Zibotentan (INN) (earlier code name ZD4054) is an anti-cancer candidate in development by AstraZeneca.

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Zimelidine

Zimelidine (INN, BAN) (brand names Zimeldine, Normud, Zelmid) was one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants to be marketed.

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Zindoxifene

Zindoxifene (INN; former developmental code names D-16726, NSC-341952) is a nonsteroidal selective estrogen receptor modulator (SERM) that was under development in the 1980s and early 1990s for the treatment of breast cancer but was not marketed.

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Zofenopril

Zofenopril (INN) is a medication that protects the heart and helps reduce high blood pressure.

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Zonampanel

Zonampanel (INN, code name YM872) is a quinoxalinedione derivative drug and competitive antagonist of the AMPA receptor which was being investigated by Yamanouchi/Astellas Pharma as a neuroprotective drug for the treatment of ischemic stroke but never completed clinical trials.

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Zorubicin

Zorubicin (INN) is an anthracycline.

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Zotarolimus

Zotarolimus (INN, codenamed ABT-578) is an immunosuppressant.

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Zoxazolamine

Zoxazolamine (INN, USAN, BAN) (brand name Contrazole, Deflexol, Flexin, Miazol, Uri-Boi, Zoxamine, Zoxine) is a muscle relaxant that is no longer marketed.

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Zuclomifene

Zuclomifene (INN; or zuclomiphene (USAN)) is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group that was never marketed.

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1,1,1,2,3,3,3-Heptafluoropropane

1,1,1,2,3,3,3-Heptafluoropropane, also called heptafluoropropane, FM200, HFC-227 or HFC-227ea (ISO name), as well as apaflurane (INN), is a colourless, odourless gaseous halocarbon commonly used as a gaseous fire suppression agent.

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1,1,1,2-Tetrafluoroethane

1,1,1,2-Tetrafluoroethane (also known as norflurane (INN), R-134a, Freon 134a, Forane 134a, Genetron 134a, Florasol 134a, Suva 134a, or HFC-134a) is a haloalkane refrigerant with thermodynamic properties similar to R-12 (dichlorodifluoromethane) but with insignificant ozone depletion potential and a somewhat lower global warming potential (1,430, compared to R-12's GWP of 10,900).

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1,2-Dichlorotetrafluoroethane

1,2-Dichlorotetrafluoroethane, or R-114, also known as cryofluorane (INN), is a chlorofluorocarbon (CFC) with the molecular formula ClF2CCF2Cl.

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11-Deoxycorticosterone

11-Deoxycorticosterone (DOC), or simply deoxycorticosterone, also known as 21-hydroxyprogesterone, as well as desoxycortone (INN), deoxycortone, and cortexone, is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone.

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11-Deoxycortisol

11-Deoxycortisol, also known as cortodoxone (INN) or cortexolone, as well as 17α,21-dihydroxyprogesterone or 17α,21-dihydroxypregn-4-ene-3,20-dione, is a glucocorticoid steroid hormone.

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2,5-Dimethoxy-4-bromoamphetamine

Dimethoxybromoamphetamine (DOB), also known as brolamfetamine (INN) and bromo-DMA, is a psychedelic drug and substituted amphetamine of the phenethylamine class of compounds.

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3,4-Methylenedioxyamphetamine

3,4-Methylenedioxyamphetamine (MDA), is an empathogen-entactogen, psychostimulant, and psychedelic drug of the amphetamine family that is encountered mainly as a recreational drug.

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4-Aminopyridine

4-Aminopyridine (4-AP, fampridine, dalfampridine) is an organic compound with the chemical formula C5H4N–NH2.

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Redirects here:

Drug naming, INNM, International Non-proprietary Name, International Nonproprietary Name, Modified INN, PINN, Proposed International Nonproprietary Name, Recommended International Non-Proprietary Name, Recommended International Non-proprietary Name, Recommended International Non-proprietary Names, Recommended International Nonproprietary Name, Recommended International Nonproprietary Names, Recommended international non-proprietary name.

References

[1] https://en.wikipedia.org/wiki/International_nonproprietary_name

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