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MCF-7

Index MCF-7

MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old Caucasian woman. [1]

49 relations: AEE788, Annexin A1, BCAS1, Biosensor, Breast cancer, C-jun, C11orf52, Carboplatin, Cell culture, Cucurbitacin E, D-15414, Dauricine, DNA origami, E-SCREEN, Epoxyeicosatrienoic acid, ERX-11, Fenarimol, Force spectrum microscopy, Free fatty acid receptor 1, Furan fatty acids, Genistin, GPR31, IQGAP1, IRS1, Krtin Nithiyanandam, Leukotriene B4 receptor 2, List of breast cancer cell lines, List of Wayne State University people, MDA-MB-468, MIBE, Mir-19 microRNA precursor family, Mir-205, Mir-26 microRNA precursor family, Mir-618 microRNA precursor family, MRN complex, NCI-60, Nomegestrol acetate, Periostin, Pioneer factor, Plumbagin, RAD51C, Raventoxin, Riceberry, Tolypocladium inflatum, Tricetin, YPEL3, 13-Hydroxyoctadecadienoic acid, 15-Hydroxyeicosatetraenoic acid, 20-Hydroxyeicosatetraenoic acid.

AEE788

AEE788 is a multitargeted human epidermal receptor (HER) 1/2 and vascular endothelial growth factor receptor (VEGFR) 1/2 receptor family tyrosine kinases inhibitor with IC50 of 2, 6, 77, 59 nM for EGFR, ErbB2, KDR, and Flt-1.

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Annexin A1

Annexin A1, also known as lipocortin I, is a protein that is encoded by the ANXA1 gene in humans.

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BCAS1

Breast carcinoma-amplified sequence 1 is a protein that in humans is encoded by the BCAS1 gene.

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Biosensor

A biosensor is an analytical device, used for the detection of an analyte, that combines a biological component with a physicochemical detector.

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Breast cancer

Breast cancer is cancer that develops from breast tissue.

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C-jun

c-Jun is a protein that in humans is encoded by the JUN gene.

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C11orf52

C11orf52 is an uncharacterized protein that in homo sapiens is encoded by the C11orf52 gene.

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Carboplatin

Carboplatin, sold under the trade name Paraplatin among others, is a chemotherapy medication used to treat a number of forms of cancer.

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Cell culture

Cell culture is the process by which cells are grown under controlled conditions, generally outside their natural environment.

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Cucurbitacin E

Cucurbitacin E is a biochemical compound from the family of cucurbitacins.

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D-15414

D-15414 is a nonsteroidal weak estrogen of the 2-phenylindole group which was never marketed.

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Dauricine

Dauricine is a plant metabolite, chemically classified as a phenol, an aromatic ether, and an isoquinoline alkaloid.

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DNA origami

DNA origami is the nanoscale folding of DNA to create non-arbitrary two- and three-dimensional shapes at the nanoscale.

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E-SCREEN

E-SCREEN is a cell proliferation assay based on the enhanced proliferation of human breast cancer cells (MCF-7) in the presence of estrogen active substances.

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Epoxyeicosatrienoic acid

The epoxyeicosatrienoic acids or EETs are signaling molecules formed within various types of cells by the metabolism of arachidonic acid by a specific subset of Cytochrome P450 enzymes termed cytochrome P450 epoxygenases.

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ERX-11

ERX-11, also known as ERα coregulator-binding modulator-11, is a novel antiestrogen and experimental hormonal antineoplastic agent which is being researched for the potential treatment of estrogen receptor-positive breast cancer.

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Fenarimol

Fenarimol, sold under the tradenames Bloc, Rimidin and Rubigan, is a fungicide which acts against rusts, blackspot and mildew fungi.

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Force spectrum microscopy

Force Spectrum Microscopy (FSM) is an application of active microrheology developed to measure aggregate random forces in the cytoplasm.

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Free fatty acid receptor 1

Free fatty acid receptor 1 (FFA1), also known as GPR40, is a class A G-protein coupled receptor that in humans is encoded by the FFAR1 gene.

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Furan fatty acids

Furan fatty acids are a group of fatty acids that contain a furan ring.

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Genistin

Genistin is an isoflavone found in a number of dietary plants like soy and kudzu.

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GPR31

G-protein coupled receptor 31 also known as 12-(S)-HETE receptor is a protein that in humans is encoded by the GPR31 gene.

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IQGAP1

Ras GTPase-activating-like protein IQGAP1 (IQGAP1) also known as p195 is a ubiquitously expressed protein that in humans is encoded by the IQGAP1 gene.

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IRS1

Insulin receptor substrate 1 (IRS-1) is a signaling adapter protein that in humans is encoded by the IRS-1 gene.

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Krtin Nithiyanandam

Krtin Nithiyanandam is a British student, scientist, and inventor.

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Leukotriene B4 receptor 2

Leukotriene B4 receptor 2, also known as BLT2, BLT2 receptor, and BLTR2, is a Integral membrane protein that is encoded by the LTB4R2 gene in humans and the Ltbr2 gene in mice.

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List of breast cancer cell lines

Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease.

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List of Wayne State University people

The following is a list of people related to Wayne State University.

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MDA-MB-468

MDA-MB-468 is a cell line that was isolated from a 51-year-old female human in 1977, and is commonly used in breast cancer research.

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MIBE

MIBE is a synthetic, nonsteroidal antiestrogen that acts as a dual antagonist of the ERα and the GPER.

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Mir-19 microRNA precursor family

There are 89 known sequences today in the microRNA 19 (miR-19) family but it will change quickly.

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Mir-205

In molecular biology miR-205 microRNA is a short RNA molecule.

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Mir-26 microRNA precursor family

The miR-26 microRNA is a small non-coding RNA that is involved in regulating gene expression.

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Mir-618 microRNA precursor family

mir-618 microRNA is a short non-coding RNA molecule belonging both to the family of microRNAs and to that of small interfering RNAs (siRNAs).

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MRN complex

The MRN complex (MRX complex in yeast) is a protein complex consisting of Mre11, Rad50 and Nbs1 (also known as Nibrin in humans and as Xrs2 in yeast).

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NCI-60

The NCI-60 cancer cell line panel is a group of 60 human cancer cell lines used by the National Cancer Institute (NCI) for the screening of compounds to detect potential anticancer activity.

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Nomegestrol acetate

Nomegestrol acetate (NOMAC), sold under the brand names Lutenyl and Zoely among others, is a progestin medication which is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders.

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Periostin

Periostin (POSTN, PN, or osteoblast-specific factor OSF-2) is a protein that in humans is encoded by the POSTN gene.

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Pioneer factor

Pioneer factors are transcription factors that can directly bind condensed chromatin.

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Plumbagin

Plumbagin or 5-hydroxy-2-methyl-1,4-naphthoquinone is an organic compound with the chemical formula.

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RAD51C

RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene.

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Raventoxin

Raventoxins are neurotoxins from the venom of the spider Macrothele raveni.

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Riceberry

Riceberry (ข้าวไรซ์เบอร์รี่) is a registered rice variety from Thailand, a cross-breed of Jao Hom Nin (JHN), a local non-glutinous purple rice and Khoa Dawk Mali 105 (hom mali rice).

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Tolypocladium inflatum

Tolypocladium inflatum is an ascomycete fungus originally isolated from a Norwegian soil sample that, under certain conditions, produces the immunosuppressant drug ciclosporin.

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Tricetin

Tricetin is a flavone, a type of flavonoid.

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YPEL3

Yippee-like 3 (Drosophila) is a protein that in humans is encoded by the YPEL3 gene.

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13-Hydroxyoctadecadienoic acid

13-Hydroxyoctadecadienoic acid (13-HODE) is the commonly used term for 13(S)-hydroxy-9Z,11E-octadecadienoic acid (13(S)-HODE).

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15-Hydroxyeicosatetraenoic acid

15-Hydroxyeicosatetraenoic acid (also termed 15-HETE, 15(S)-HETE, and 15S-HETE) is an eicosanoid, i.e. a metabolite of arachidonic acid.

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20-Hydroxyeicosatetraenoic acid

20-Hydroxyeicosatetraenoic acid, also known as 20-HETE or 20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid, is an eicosanoid metabolite of arachidonic acid that has a wide range of effects on the vascular system including the regulation of vascular tone, blood flow to specific organs, sodium and fluid transport in the kidney, and vascular pathway remodeling.

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Redirects here:

MCF 7, MCF7.

References

[1] https://en.wikipedia.org/wiki/MCF-7

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