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Metabolomics

Index Metabolomics

Metabolomics is the scientific study of chemical processes involving metabolites, the small molecule intermediates and products of metabolism. [1]

124 relations: Agrophysics, Analytical chemistry, ArrayTrack, Association of Biomolecular Resource Facilities, AstridBio, Benjamin Cravatt III, Bioanalysis (journal), Biochemistry, Bioinformatics, Biological database, Biological Magnetic Resonance Data Bank, Biomarker discovery, BioUML, Botany, Bruce Rittmann, Chelidonine, Chemometrics, Christoph Steinbeck, Comprehensive two-dimensional gas chromatography, CyberCell, Cynthia Larive, Cytomics, Daniel Promislow, David C. Muddiman, David E. Clemmer, Dichlorodiphenyldichloroethane, Douglas Kell, DrugBank, E. Coli Metabolome Database, Eline Slagboom, Enzyme Function Initiative, Exometabolomics, Extrapolation based molecular systems biology, Foodomics, Functional genomics, Gene prediction, Genedata, GeneLab, Genomics, George Delahunty, German Network for Bioinformatics Intrastructure, Glycolysis, Glycomics, Golm Metabolome Database, Hormone, Human Metabolome Database, Human Microbiome Project, In vivo magnetic resonance spectroscopy, Index of biotechnology articles, Ion-mobility spectrometry, ..., Isothermal microcalorimetry, Isotopic ratio outlier analysis, Jeffrey Skolnick, Jenefer Blackwell, Jeremy K. Nicholson, Joanneum Research, Jonathan Dordick, KEGG, Kendrick mass, LECO Corporation, Liquid chromatography–mass spectrometry, List of academic databases and search engines, List of omics topics in biology, Masaru Tomita, Matthew Dalby, Melvin H. Knisely, MetaboAnalyst, MetaboLights, Metabolite, Metabolite damage, Metabolite Set Enrichment Analysis, Metabolome, Metabolomic Pathway Analysis, Metabolomics, Metagenomics, Metallome, METLIN, Molecular medicine, Molecular Systems Biology, Monolithic HPLC column, National Center for Integrative Biomedical Informatics, Natural scientific research in Canada, Network medicine, Neuromuscular-blocking drug, Nuclear magnetic resonance, Nutritional genomics, Omics, Ontology for Biomedical Investigations, OpenMS, Orbitrap, Orthogonal signal correction, Panomics, Paul J. Gemperline, Pedro Pedrosa Mendes, Pennington Biomedical Research Center, Pharmacometabolomics, Phycotoxin, Pinolenic acid, Plants for Human Health Institute, Primary metabolite, Principal component analysis, Promoter activity, Proteomics, Quoats, Rafael Bruschweiler, Rank product, Receiver Operating Characteristic Curve Explorer and Tester, Researchsome, Single-cell analysis, Single-cell variability, Skyline (software), Small Molecule Pathway Database, Substantial equivalence, Surface-assisted laser desorption/ionization, Susmita Datta, Systems biology, Toxicogenomics, Toxin and Toxin-Target Database, Toyohashi University of Technology, Transcriptomics technologies, Translational research informatics, Volcano plot (statistics), W. Ian Lipkin, Yeast Metabolome Database. Expand index (74 more) »

Agrophysics

Agrophysics is a branch of science bordering on agronomy and physics, whose objects of study are the agroecosystem - the biological objects, biotope and biocoenosis affected by human activity, studied and described using the methods of physical sciences.

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Analytical chemistry

Analytical chemistry studies and uses instruments and methods used to separate, identify, and quantify matter.

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ArrayTrack

ArrayTrack is a multi-purpose bioinformatics tool primarily used for microarray data management, analysis, and interpretation.

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Association of Biomolecular Resource Facilities

The Association of Biomolecular Resource Facilities is dedicated to advancing core and research biotechnology laboratories through research, communication, and education.

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AstridBio

AstridBio Ltd. is a privately held Biotechnology company with office in Hungary.

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Benjamin Cravatt III

Benjamin Franklin Cravatt III is a professor in and chair of the Department of Chemical Physiology at The Scripps Research Institute in La Jolla, California.

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Bioanalysis (journal)

Bioanalysis is a biweekly peer-reviewed scientific journal established in 2009 and published by Future Science.

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Biochemistry

Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms.

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Bioinformatics

Bioinformatics is an interdisciplinary field that develops methods and software tools for understanding biological data.

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Biological database

Biological databases are libraries of life sciences information, collected from scientific experiments, published literature, high-throughput experiment technology, and computational analysis.

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Biological Magnetic Resonance Data Bank

The Biological Magnetic Resonance Data Bank (BioMagResBank or BMRB) is an open access repository of nuclear magnetic resonance (NMR) spectroscopic data from peptides, proteins, nucleic acids and other biologically relevant molecules.

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Biomarker discovery

Biomarker discovery is a medical term describing the process by which biomarkers are discovered.

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BioUML

BioUML is an open-source software platform for the analysis of data from omics sciences research and other advanced computational biology developed by scientists from the Institute of Systems Biology in Novosibirsk, Russia.

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Botany

Botany, also called plant science(s), plant biology or phytology, is the science of plant life and a branch of biology.

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Bruce Rittmann

Bruce E. Rittmann is Regents' Professor of Environmental Engineering and Director of the at the Biodesign Institute of Arizona State University, and a member of both the Civil Engineering and the Chemical Engineering Sections of the National Academy of Engineering.

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Chelidonine

(Chelidonine is an isolate of Papaveraceae with acetylcholinesterase and butyrylcholinesterase inhibitory activity.

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Chemometrics

Chemometrics is the science of extracting information from chemical systems by data-driven means.

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Christoph Steinbeck

Christoph Steinbeck is a chemist born in Neuwied in 1966 and has a professorship for analytical chemistry, cheminformatics and chemometrics at the Friedrich-Schiller-Universität Jena in Thuringia, Germany.

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Comprehensive two-dimensional gas chromatography

Comprehensive Two-dimensional gas chromatography, or GCxGC is a multidimensional gas chromatography technique that was originally described in 1991 by Professor Phillips and his student Liu.

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CyberCell

The CyberCell Database (CCDB) is a freely available, web-accessible database that provides quantitative genomic, proteomic as well metabolomic data on Escherichia coli.

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Cynthia Larive

Cynthia Larive is an American bioanalytical chemist known for developing new instrumentation and analysis techniques involving nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry.

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Cytomics

Cytomics is the study of cell biology (cytology) and biochemistry in cellular systems at the single cell level.

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Daniel Promislow

Daniel Promislow is a biogerontologist and a professor at the University of Washington.

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David C. Muddiman

David C. Muddiman is an American chemist and distinguished professor of chemistry at North Carolina State University in Raleigh, North Carolina.

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David E. Clemmer

David E. Clemmer (February 23, 1965, Alamosa, Colorado -) is an analytical chemist and the Distinguished Professor and Robert and Marjorie Mann Chair of Chemistry at Indiana University in Bloomington, Indiana, where he leads the Clemmer Group.

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Dichlorodiphenyldichloroethane

Dichlorodiphenyldichloroethane (DDD) is an organochlorine insecticide that is slightly irritating to the skin.

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Douglas Kell

Douglas Bruce Kell (born 7 April 1953) is a British biochemist and Professor of Bioanalytical Sciences in the School of Chemistry at the University of Manchester, based in the Manchester Institute of Biotechnology (MIB).

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DrugBank

The DrugBank database is a comprehensive, freely accessible, online database containing information on drugs and drug targets.

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E. Coli Metabolome Database

The E. coli Metabolome Database (ECMDB) is a comprehensive, high-quality, freely accessible, online database of small molecule metabolites found in or produced by Escherichia coli (E. coli strain K12, MG1655).

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Eline Slagboom

P.

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Enzyme Function Initiative

The Enzyme Function Initiative (EFI) is a large-scale collaborative project aiming to develop and disseminate a robust strategy to determine enzyme function through an integrated sequence–structure-based approach.

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Exometabolomics

Exometabolomics, also known as 'metabolic footprinting', is the study of extracellular metabolites and is a sub-field of metabolomics.

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Extrapolation based molecular systems biology

Extrapolation based Molecular Systems Biology is the utilization of molecular data from one or many sub-cellular levels to indirectly infer the remaining components of a sub-cellular system via statistical algorithms and priori biological knowledge.

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Foodomics

Foodomics was defined in 2009 as "a discipline that studies the Food and Nutrition domains through the application and integration of advanced -omics technologies to improve consumer's well-being, health, and knowledge".

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Functional genomics

Functional genomics is a field of molecular biology that attempts to make use of the vast wealth of data given by genomic and transcriptomic projects (such as genome sequencing projects and RNA sequencing) to describe gene (and protein) functions and interactions.

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Gene prediction

In computational biology, gene prediction or gene finding refers to the process of identifying the regions of genomic DNA that encode genes.

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Genedata

Genedata is a bioinformatics solution provider headquartered in Basel, Switzerland.

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GeneLab

GeneLab is an open-access, collaborative analysis platform for space bioscience research.

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Genomics

Genomics is an interdisciplinary field of science focusing on the structure, function, evolution, mapping, and editing of genomes.

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George Delahunty

George B. Delahunty (born May 5, 1952) is an American physiologist and endocrinologist.

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German Network for Bioinformatics Intrastructure

The 'German Network for Bioinformatics Infrastructure – de.NBI' is a national, academic and non-profit infrastructure supported by the Federal Ministry of Education and Research providing bioinformatics services to users in life sciences research and biomedicine in Germany and Europe.

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Glycolysis

Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+.

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Glycomics

Glycomics is the comprehensive study of glycomes (the entire complement of sugars, whether free or present in more complex molecules of an organism), including genetic, physiologic, pathologic, and other aspects.

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Golm Metabolome Database

The Golm Metabolome Database (GMD) is a gas chromatography (GC) – mass spectrometry (MS) reference library dedicated to metabolite profiling experiments and comprises mass spectral and retention index (RI) information for non-annotated mass spectral tags (MSTs, mass spectral information with retention time attached indices) together with data of a multitude of already identified metabolites and reference substances.

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Hormone

A hormone (from the Greek participle “ὁρμῶ”, "to set in motion, urge on") is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour.

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Human Metabolome Database

The Human Metabolome Database (HMDB) is a comprehensive, high-quality, freely accessible, online database of small molecule metabolites found in the human body.

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Human Microbiome Project

The Human Microbiome Project (HMP) was a United States National Institutes of Health (NIH) research initiative to improve understanding of the microbial flora involved in human health and disease.

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In vivo magnetic resonance spectroscopy

In vivo magnetic resonance spectroscopy (MRS) is a specialized technique associated with magnetic resonance imaging (MRI).

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Index of biotechnology articles

Biotechnology is a technology based on biology, especially when used in agriculture, food science, and medicine.

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Ion-mobility spectrometry

Ion-mobility spectrometry (IMS) is an analytical technique used to separate and identify ionized molecules in the gas phase based on their mobility in a carrier buffer gas.

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Isothermal microcalorimetry

Isothermal microcalorimetry (IMC) is a laboratory method for real-time monitoring and dynamic analysis of chemical, physical and biological processes.

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Isotopic ratio outlier analysis

Isotopic ratio outlier analysis (IROA) is a stable isotopic labeling technique that utilizes the creation of distinct signatures in the molecules of a biological sample for identification and quantification.

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Jeffrey Skolnick

Jeffrey Skolnick is an American computational biologist.

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Jenefer Blackwell

Jenefer Blackwell is a Professor of Molecular Parasitology at the Telethon Kids Institute in the University of Western Australia.

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Jeremy K. Nicholson

Jeremy K. Nicholson is a professor of biological chemistry and head of the Department of Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics at the Imperial College London.

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Joanneum Research

JOANNEUM RESEARCH Forschungsgesellschaft mbH is one of the largest non-academic research institutes in Austria.

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Jonathan Dordick

Jonathan S. Dordick (born January 15, 1959) is the Howard P. Isermann Professor of Biochemical Engineering at Rensselaer Polytechnic Institute.

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KEGG

KEGG (Kyoto Encyclopedia of Genes and Genomes) is a collection of databases dealing with genomes, biological pathways, diseases, drugs, and chemical substances.

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Kendrick mass

The Kendrick mass is defined by setting the mass of a chosen molecular fragment, typically CH2, to an integer value in atomic mass units.

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LECO Corporation

LECO Corporation, founded in 1936 by Carl Schultz and George Krasl, operates its analytical instrumentation research and development, and manufacturing from its headquarters located in St. Joseph, Michigan.

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Liquid chromatography–mass spectrometry

Liquid chromatography–mass spectrometry (LC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS).

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List of academic databases and search engines

This page contains a representative list of major databases and search engines useful in an academic setting for finding and accessing articles in academic journals, repositories, archives, or other collections of scientific and other articles.

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List of omics topics in biology

Inspired by the terms genome and genomics, other words to describe complete biological datasets, mostly sets of biomolecules originating from one organism, have been coined with the suffix -ome and -omics.

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Masaru Tomita

is a Japanese molecular biologist and computer scientist, best known as the director of the E-Cell simulation environment software and/or the inventor of GLR parser algorithm.

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Matthew Dalby

Matthew John Dalby FRSE FRSB is Professor of Cell Engineering at the University of Glasgow.

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Melvin H. Knisely

Melvin Henry Knisely (17 June 1904 - 30 March 1975), was an American physiologist who first observed the pathological clumping of red and white cells, in vivo, at the capillary level.

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MetaboAnalyst

MetaboAnalyst is a set of online tools for metabolomic data analysis and interpretation, created by members of the Wishart Research Group at the University of Alberta.

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MetaboLights

MetaboLights is a data repository founded in 2012 for cross-species and cross-platform metabolomic studies that provides primary research data and meta data for metabolomic studies as well as a knowledge base for properties of individual metabolites.

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Metabolite

A metabolite is the intermediate end product of metabolism.

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Metabolite damage

Metabolite damage can occur through enzyme promiscuity or spontaneous chemical reactions.

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Metabolite Set Enrichment Analysis

Metabolite Set Enrichment Analysis (MSEA) is a method designed to help metabolomics researchers identify and interpret patterns of metabolite concentration changes in a biologically meaningful way.

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Metabolome

The metabolome refers to the complete set of small-molecule chemicals found within a biological sample.

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Metabolomic Pathway Analysis

Metabolomic Pathway Analysis, shortened to MetPA, is a freely available, user-friendly web server to assist with the identification analysis and visualization of metabolic pathways using metabolomic data.

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Metabolomics

Metabolomics is the scientific study of chemical processes involving metabolites, the small molecule intermediates and products of metabolism.

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Metagenomics

Metagenomics is the study of genetic material recovered directly from environmental samples.

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Metallome

In biochemistry, the metallome distribution of free metal ions in every one of cellular compartments.

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METLIN

The METLIN Metabolomics Database is a repository of metabolite information as well as tandem mass spectrometry data.

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Molecular medicine

Molecular medicine is a broad field, where physical, chemical, biological, bioinformatics and medical techniques are used to describe molecular structures and mechanisms, identify fundamental molecular and genetic errors of disease, and to develop molecular interventions to correct them.

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Molecular Systems Biology

Molecular Systems Biology is an open-access peer-reviewed scientific journal publishing research within systems biology at the molecular level, including genomics, proteomics, metabolomics, microbial systems, the integration of cell signaling and regulatory networks, and synthetic biology.

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Monolithic HPLC column

A monolithic HPLC column, or monolithic column, is a column used in high-performance liquid chromatography (HPLC).

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National Center for Integrative Biomedical Informatics

The National Center for Integrative Biomedical Informatics (NCIBI) is one of seven National Centers for Biomedical Computing funded by the National Institutes of Health's (NIH) Roadmap for Medical Research.

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Natural scientific research in Canada

This article outlines the history of natural scientific research in Canada, including physics, astronomy, space science, geology, oceanography, chemistry, biology, and medical research.

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Network medicine

Network medicine is the application of network science towards identifying, preventing, and treating diseases.

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Neuromuscular-blocking drug

Neuromuscular-blocking drugs block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles.

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Nuclear magnetic resonance

Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a magnetic field absorb and re-emit electromagnetic radiation.

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Nutritional genomics

Nutritional genomics is a science studying the relationship between human genome, nutrition and health.

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Omics

The English-language neologism omics informally refers to a field of study in biology ending in -omics, such as genomics, proteomics or metabolomics.

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Ontology for Biomedical Investigations

The Ontology for Biomedical Investigations (OBI) is an open-access, integrated ontology for the description of biological and clinical investigations.

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OpenMS

OpenMS is an open-source project for data analysis and processing in protein mass spectrometry and is released under the 3-clause BSD licence.

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Orbitrap

In mass spectrometry, Orbitrap is an ion trap mass analyzer consisting of an outer barrel-like electrode and a coaxial inner spindle-like electrode that traps ions in an orbital motion around the spindle.

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Orthogonal signal correction

Orthogonal Signal Correction (OSC) is a spectral preprocessing technique that removes variation from a data matrix X that is orthogonal to the response matrix Y. OSC was introduced by researchers at the University of Umea in 1998 and has since found applications in domains including metabolomics.

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Panomics

"Panomics" or 'pan-omics' refers to the range of molecular biology technologies including genomics, proteomics, metabolomics, transcriptomics, and so forth, or the integration of their combined use.

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Paul J. Gemperline

Dr.

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Pedro Pedrosa Mendes

Pedro Pedrosa Mendes is a Professor of Computational Systems Biology in the School of Computer Science at the University of Manchester.

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Pennington Biomedical Research Center

The Pennington Biomedical Research Center, located in Baton Rouge, Louisiana, is a campus of the Louisiana State University System and conducts clinical, basic, and population science research.

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Pharmacometabolomics

Pharmacometabolomics, also known as pharmacometabonomics, is a field which stems from metabolomics, the quantification and analysis of metabolites produced by the body.

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Phycotoxin

Phycotoxins (from Greek, phykos, "seaweed"; and toxikon, "toxin") are complex allelopathic chemicals produced by eukaryotic and prokaryotic algal secondary metabolic pathways.

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Pinolenic acid

Pinolenic acid (often misspelled as pinoleic acid) is a fatty acid contained in Siberian Pine nuts, Korean Pine nuts and the seeds of other pines (Pinus species).

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Plants for Human Health Institute

The Plants for Human Health Institute (PHHI) is a North Carolina State University research and education organization located at the North Carolina Research Campus in Kannapolis, North Carolina, United States.

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Primary metabolite

A primary metabolite is a kind of metabolite that is directly involved in normal growth, development, and reproduction.

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Principal component analysis

Principal component analysis (PCA) is a statistical procedure that uses an orthogonal transformation to convert a set of observations of possibly correlated variables into a set of values of linearly uncorrelated variables called principal components.

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Promoter activity

Promoter activity is a term that encompasses several meanings around the process of gene expression from regulatory sequences —promoters and enhancers.

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Proteomics

Proteomics is the large-scale study of proteins.

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Quoats

Quoats is a LINK research project funded by government, levy boards and industry groups that aims to develop and apply state-of-the-art genomic and metabolomic tools for the genetic improvement of oats.

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Rafael Bruschweiler

Rafael Brüschweiler is a scientist who studies nuclear magnetic resonance (NMR).

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Rank product

The rank product is a biologically motivated test for the detection of differentially expressed genes in replicated microarray experiments.

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Receiver Operating Characteristic Curve Explorer and Tester

Receiver Operating Characteristic Curve Explorer and Tester (ROCCET) is an open-access web server for performing biomarker analysis using ROC (Receiver Operating Characteristic) curve analyses on metabolomic data sets.

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Researchsome

Researchsome belongs to the -omics set of words, which comprises genomics, proteomics, metabolomics and related words dealing with scientific research, mostly in the biological sciences and related disciplines, like bioinformatics.

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Single-cell analysis

In the field of cellular biology, single-cell analysis is the study of genomics, transcriptomics, proteomics and metabolomics at the single cell level.

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Single-cell variability

In cell biology, single-cell variability occurs when individual cells in an otherwise similar population differ in shape, size, position in the cell cycle, or molecular-level characteristics.

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Skyline (software)

Skyline is an open source software for targeted proteomics and metabolomics data analysis.

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Small Molecule Pathway Database

The Small Molecule Pathway Database (SMPDB) is a comprehensive, high-quality, freely accessible, online database containing more than 600 small molecule (i.e. metabolic) pathways found in humans.

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Substantial equivalence

In food safety, the concept of substantial equivalence holds that the safety of a new food, particularly one that has been genetically modified (GM), may be assessed by comparing it with a similar traditional food that has proven safe in normal use over time.

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Surface-assisted laser desorption/ionization

Surface-assisted laser desorption/ionization (SALDI) is a soft laser desorption technique used for mass spectrometry analysis of biomolecules, polymers, and small organic molecules.

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Susmita Datta

Susmita Datta is an Indian biostatistician.

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Systems biology

Systems biology is the computational and mathematical modeling of complex biological systems.

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Toxicogenomics

Toxicogenomics is a subdiscipline of pharmacology that deals with the collection, interpretation, and storage of information about gene and protein activity within a particular cell or tissue of an organism in response to exposure to toxic substances.

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Toxin and Toxin-Target Database

The Toxin and Toxin-Target Database (T3DB), also known as the Toxic Exposome Database, is a freely accessible online database of common substances that are toxic to humans, along with their protein, DNA or organ targets.

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Toyohashi University of Technology

Toyohashi University of Technology (豊橋技術科学大学; Toyohashi Gijutsu Kagaku Daigaku), often abbreviated to Toyohashi Tech, or TUT, is a national engineering university located in Toyohashi, Aichi, Japan.

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Transcriptomics technologies

Transcriptomics technologies are the techniques used to study an organism’s transcriptome, the sum of all of its RNA transcripts.

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Translational research informatics

Translational research informatics (TRI) is a sister domain to or a sub-domain of biomedical informatics or medical informatics concerned with the application of informatics theory and methods to translational research.

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Volcano plot (statistics)

In statistics, a volcano plot is a type of scatter-plot that is used to quickly identify changes in large data sets composed of replicate data.

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W. Ian Lipkin

W. Ian Lipkin (born 1952) is the John Snow Professor of Epidemiology at the Mailman School of Public Health at Columbia University and Professor of Neurology and Pathology at the College of Physicians and Surgeons at Columbia University. Lipkin is also Director of the Center for Infection and Immunity, an academic laboratory for microbe hunting in acute and chronic diseases.

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Yeast Metabolome Database

The Yeast Metabolome Database (YMDB) is a comprehensive, high-quality, freely accessible, online database of small molecule metabolites found in or produced by Saccharomyces cerevisiae (Baker’s yeast).

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Metabolite profiling, Metabolomic, Metabonome, Metabonomics, 代谢物组学.

References

[1] https://en.wikipedia.org/wiki/Metabolomics

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