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82 relations: Aldosterone, Allylestrenol, Étienne-Émile Baulieu, Bicalutamide, Coactivator (genetics), Comparison of bicalutamide with other antiandrogens, COUP-TFI, Dehydroepiandrosterone sulfate, Desogestrel, Diethylstilbestrol, Discovery and development of antiandrogens, EM-5854, Embryonal fyn-associated substrate, Enzyme promiscuity, Epigenetics of depression, Esaxerenone, Estradiol, Estradiol (medication), Estradiol sulfate, Estriol (medication), Estrogen (medication), Estrogen receptor, Estrogen-related receptor beta, Estrogen-related receptor gamma, Ethynylandrostanediol, Finerenone, FKBP52, Genome editing, Ginsenoside, Glucocorticoid receptor, GT198, Guggulsterone, Hormone, Hormone receptor, Hsp90, HSP90AB1, Index of biochemistry articles, Index of genetics articles, List of MeSH codes (D12.776), List of MeSH codes (D12.776.930), List of neurosteroids, List of steroid esters, List of steroid medications available in the United States, List of steroids, Loteprednol, Medrogestone, Medroxyprogesterone acetate, Membrane steroid receptor, Mifepristone, MK-0773, ..., Neurosteroid, Noise-induced hearing loss, Nonsteroidal, Noretynodrel, Norgestimate, Nuclear receptor, Pharmacology of bicalutamide, Posttraumatic stress disorder, PTGES3, Retroprogesterone, RU-59063, Selective progesterone receptor modulator, Selective receptor modulator, Serum response factor, Sex hormone receptor, Sex steroid, Signal transduction, SRA1, Steroid ester, Steroid hormone, Steroid sulfate, Stress (biology), Transcription factor, Trimegestone, Triterpene, Tuberous sclerosis protein, Vinclozolin, Vitamin D, Zinc finger, 18-Methylsegesterone acetate, 4-Androstadienol, 5α-Dihydroethisterone. Expand index (32 more) »
Aldosterone
Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.
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Allylestrenol
Allylestrenol, sold under the brand names Gestanin and Turinal among others, is a progestin medication which is used to treat recurrent and threatened miscarriage and to prevent premature labor in pregnant women.
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Étienne-Émile Baulieu
Étienne-Émile Baulieu (born 12 December 1926) is a French biochemist and endocrinologist who is best known for his research in the field of steroid hormones and their role in reproduction and aging.
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Bicalutamide
Bicalutamide, sold under the brand name Casodex among others, is an antiandrogen medication that is primarily used to treat prostate cancer.
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Coactivator (genetics)
A coactivator is a type of transcriptional coregulator that binds to an activator (a transcription factor) to increase the rate of transcription of a gene or set of genes.
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Comparison of bicalutamide with other antiandrogens
Comparison of the nonsteroidal antiandrogen (NSAA) bicalutamide with other antiandrogens reveals differences between the medications in terms of efficacy, tolerability, safety, and other parameters.
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COUP-TFI
COUP-TF1 (COUP Transcription Factor 1) also known as NR2F1 (Nuclear Receptor subfamily 2, group F, member 1) is a protein that in humans is encoded by the NR2F1 gene.
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Dehydroepiandrosterone sulfate
Dehydroepiandrosterone sulfate, abbreviated as DHEA sulfate or DHEA-S, also known as androstenolone sulfate, is an endogenous androstane steroid that is produced by the adrenal cortex.
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Desogestrel
Desogestrel, sold under the brand names Cerazette and Mircette among many others, is a progestin medication which is used in birth control pills for women.
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Diethylstilbestrol
Diethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is an estrogen medication which is mostly no longer used.
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Discovery and development of antiandrogens
This article is about the discovery and development of antiandrogens, or androgen receptor (AR) antagonists.
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EM-5854
EM-5854 is a steroidal antiandrogen which is or was under development by Endoceutics, Inc.
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Embryonal fyn-associated substrate
Embryonal fyn-associated substrate is a protein that in humans is encoded by the EFS gene.
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Enzyme promiscuity
Enzyme promiscuity is the ability of an enzyme to catalyse a fortuitous side reaction in addition to its main reaction.
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Epigenetics of depression
Major depressive disorder is heavily influenced by environmental and genetic factors.
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Esaxerenone
Esaxerenone (INN) (developmental code names CS-3150, XL-550) is a nonsteroidal antimineralocorticoid which was discovered by Exelixis and is now under development by Daiichi Sankyo Company for the treatment of hypertension, essential hypertension, hyperaldosteronism, and diabetic nephropathies.
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Estradiol
Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.
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Estradiol (medication)
Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.
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Estradiol sulfate
Estradiol sulfate (E2S), or 17β-estradiol 3-sulfate, is a natural, endogenous steroid and an estrogen ester.
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Estriol (medication)
Estriol, sold under the brand name Ovestin among others, is an estrogen medication and naturally occurring steroid hormone which is used in menopausal hormone therapy.
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Estrogen (medication)
An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
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Estrogen receptor
Estrogen receptors (ERs) are a group of proteins found inside cells.
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Estrogen-related receptor beta
Estrogen-related receptor beta (ERR-β), also known as NR3B2 (nuclear receptor subfamily 3, group B, member 2), is a nuclear receptor that in humans is encoded by the ESRRB (EStrogen Related Receptor Beta) gene.
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Estrogen-related receptor gamma
Estrogen-related receptor gamma (ERR-gamma), also known as NR3B3 (nuclear receptor subfamily 3, group B, member 3), is a nuclear receptor that in humans is encoded by the ESRRG (EStrogen Related Receptor Gamma) gene.
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Ethynylandrostanediol
Ethynylandrostanediol (developmental code name HE-3235), or 17α-ethynyl-5α-androstane-3α,17β-diol, also known as Apoptone, is a synthetic, orally active, 17α-substituted analogue of the androstanediols which was under development for the treatment of prostate cancer and breast cancer but was discontinued.
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Finerenone
Finerenone (INN, USAN) (developmental code name BAY-94-8862) is a nonsteroidal antimineralocorticoid that is in phase III clinical trials for the treatment of chronic heart failure.
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FKBP52
FK506-binding protein 4 is a protein that in humans is encoded by the FKBP4 gene.
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Genome editing
Genome editing, or genome engineering is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism.
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Ginsenoside
Ginsenosides or panaxosides are a class of natural product steroid glycosides and triterpene saponins.
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Glucocorticoid receptor
The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind.
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GT198
GT198 is a human oncogene (gene symbol PSMC3IP, alias TBPIP or Hop2) located within the BRCA1 locus at chromosome 17q21.
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Guggulsterone
Guggulsterone is a phytosteroid found in the resin of the guggul plant, Commiphora mukul.
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Hormone
A hormone (from the Greek participle “ὁρμῶ”, "to set in motion, urge on") is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour.
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Hormone receptor
A hormone receptor is a receptor molecule that binds to a specific hormone.
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Hsp90
Hsp90 (heat shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation.
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HSP90AB1
Heat shock protein HSP 90-beta also called HSP90beta is a protein that in humans is encoded by the HSP90AB1 gene.
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Index of biochemistry articles
Biochemistry is the study of the chemical processes in living organisms.
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Index of genetics articles
Genetics (from Ancient Greek γενετικός genetikos, “genite” and that from γένεσις genesis, “origin”), a discipline of biology, is the science of heredity and variation in living organisms.
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List of MeSH codes (D12.776)
This is part of the list of the "D" codes for MeSH.
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List of MeSH codes (D12.776.930)
This is a sub-part (transcription factors only) of List of MeSH codes (D12.776), itself a part of the list of the "D" codes for MeSH.
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List of neurosteroids
This is a list of neurosteroids, or natural and synthetic steroids that are active on the mammalian nervous system through receptors other than steroid hormone receptors.
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List of steroid esters
List of steroid esters may refer to.
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List of steroid medications available in the United States
List of steroid medications available in the United States may refer to.
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List of steroids
List of steroids may refer to.
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Loteprednol
Loteprednol (as the ester loteprednol etabonate) is a corticosteroid used to treat inflammations of the eye.
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Medrogestone
Medrogestone, sold under the brand name Colprone among others, is a progestin medication which has been used in menopausal hormone therapy and in the treatment of gynecological disorders.
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Medroxyprogesterone acetate
Medroxyprogesterone acetate (MPA), sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type.
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Membrane steroid receptor
Membrane steroid receptors (mSRs), also called extranuclear steroid receptors, are a class of cell surface receptors activated by endogenous steroids that mediate rapid, non-genomic signaling via modulation of intracellular signaling cascades.
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Mifepristone
Mifepristone, also known as RU-486, is a medication typically used in combination with misoprostol, to bring about an abortion.
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MK-0773
MK-0773, also known as PF-05314882, is a steroidal, orally active selective androgen receptor modulator (SARM) that was under development by Merck and GTx for the treatment of sarcopenia (loss of muscle mass) in women and men.
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Neurosteroid
Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors.
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Noise-induced hearing loss
Noise-induced hearing loss (NIHL) is hearing impairment resulting from exposure to loud sound.
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Nonsteroidal
Nonsteroidal is a term which is used to describe a compound that is not a steroid.
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Noretynodrel
Noretynodrel, or norethynodrel, sold under the brand name Enovid among others, is a progestin medication which was previously used in birth control pills and in the treatment of gynecological disorders but is now no longer marketed. It was available both alone and in combination with an estrogen. The medication is taken by mouth. Noretynodrel is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It is a relatively weak progestogen. The medication has weak estrogenic activity, no or only very weak androgenic activity, and no other important hormonal activity. It is a prodrug of various active metabolites in the body, such as norethisterone among others. Noretynodrel was introduced for medical use in 1957. It was specifically approved at this time in combination with mestranol for the treatment of gynecological and menstrual disorders. Subsequently, in 1960, this formulation was approved for use as a birth control pill. It was the first birth control pill to be introduced, and was followed by birth control pills containing norethisterone and other progestins shortly thereafter. Due to its nature as a relatively weak progestogen, noretynodrel is no longer used in medicine. As such, it is no longer marketed.
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Norgestimate
Norgestimate, sold under the brand names Ortho Tri-Cyclen and Previfem among others, is a progestin medication which is used in birth control pills for women and in menopausal hormone therapy.
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Nuclear receptor
In the field of molecular biology, nuclear receptors are a class of proteins found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules.
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Pharmacology of bicalutamide
The pharmacology of bicalutamide, a nonsteroidal antiandrogen (NSAA), has been well-characterized.
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Posttraumatic stress disorder
Posttraumatic stress disorder (PTSD)Acceptable variants of this term exist; see the Terminology section in this article.
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PTGES3
Prostaglandin E synthase 3 (cytosolic) is an enzyme that in humans is encoded by the PTGES3 gene.
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Retroprogesterone
Retroprogesterone, also known as 9β,10α-progesterone or as 9β,10α-pregn-4-ene-3,20-dione, is a progestin which was never marketed.
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RU-59063
RU-59063 is a nonsteroidal androgen or selective androgen receptor modulator (SARM) which was first described in 1994 and was never marketed.
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Selective progesterone receptor modulator
A selective progesterone receptor modulator (SPRM) is an agent that acts on the progesterone receptor.
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Selective receptor modulator
In the field of pharmacology, a selective receptor modulator or SRM is a type of drug that has different effects in different tissues.
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Serum response factor
Serum response factor, also known as SRF, is a transcription factor protein.
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Sex hormone receptor
The sex hormone receptors, or sex steroid receptors, are a group of steroid hormone receptors that interact with the sex hormones, the androgens, estrogens, and progestogens, as well as with sex-hormonal agents such as anabolic steroids, progestins, and antiestrogens.
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Sex steroid
Sex steroids, also known as gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate androgen or estrogen receptors.
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Signal transduction
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.
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SRA1
Steroid receptor RNA activator 1 also known as steroid receptor RNA activator protein (SRAP) is a protein that in humans is encoded by the SRA1 gene.
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Steroid ester
A steroid ester is an ester of a steroid.
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Steroid hormone
A steroid hormone is a steroid that acts as a hormone.
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Steroid sulfate
Steroid sulfates are endogenous sulfate esters of steroids.
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Stress (biology)
Physiological or biological stress is an organism's response to a stressor such as an environmental condition.
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Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
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Trimegestone
Trimegestone, sold under the brand names Ondeva and Totelle among others, is a progestin medication which is used in menopausal hormone therapy and in the prevention of postmenopausal osteoporosis.
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Triterpene
Triterpenes are a class of chemical compounds composed of three terpene units with the molecular formula C30H48; they may also be thought of as consisting of six isoprene units.
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Tuberous sclerosis protein
Tuberous sclerosis proteins 1 and 2, also known as TSC1 (hamartin) and TSC2 (tuberin), form a protein-complex.
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Vinclozolin
Vinclozolin (trade names Ronilan, Curalan, Vorlan, Touche) is a common dicarboximide fungicide used to control diseases, such as blights, rots and molds in vineyards, and on fruits and vegetables such as raspberries, lettuce, kiwi, snap beans, and onions.
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Vitamin D
Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and multiple other biological effects.
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Zinc finger
A zinc finger is a small protein structural motif that is characterized by the coordination of one or more zinc ions (Zn2+) in order to stabilize the fold.
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18-Methylsegesterone acetate
18-Methylsegesterone acetate (18-methyl-SGA; also known as 18-methylnestorone) is a progestin medication of the 19-norprogesterone group which was never marketed.
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4-Androstadienol
4-Androstadienol (developmental code name PH94B; tentative commercial name Aloradine or Aloradine IN), also known as 4,16-androstadien-3β-ol, is a pherine or synthetic pheromone which is under development by Pherin Pharmaceuticals, Inc.
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5α-Dihydroethisterone
5α-Dihydroethisterone (5α-DHET; developmental code name HE-3562) is an active metabolite of the formerly clinically used but now-discontinued progestin ethisterone and the experimental and never-marketed hormonal antineoplastic agent ethynylandrostanediol (HE-3235).
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Glucocorticoid receptors, Receptors, steroid, Steroid hormone receptors, Steroid receptor, Steroid receptors.
References
[1] https://en.wikipedia.org/wiki/Steroid_hormone_receptor
