Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Android™ device!
Install
Faster access than browser!
 

Telomerase

Index Telomerase

Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. [1]

148 relations: -ase, ACD (gene), Adrenocortical carcinoma, Ageing, Alexey Olovnikov, Astragalus, Astragalus propinquus, Biological immortality, Bloomberg Distinguished Professorships, Bryant Villeponteau, Cajal body, Cancer stem cell, Carcinogenesis, Carol W. Greider, Cell culture, Cell division, Cerebroretinal microangiopathy with calcifications and cysts, Child abuse, Cladonia furcata, Clone (cell biology), Complex systems biology, CST Complex, Cycloastragenol, Darwin Awards, DNA, DNA polymerase, DNA replication, DNA-binding domain, Elizabeth Blackburn, Embryonic stem cell, Endothelial colony forming cell, Epithelioid sarcoma, Eternal youth, Eukaryotic DNA replication, Experimental cancer treatment, Frederick Sanger, G-quadruplex, Gambogic acid, Genome (book), Germline, Geron Corporation, Gustav Gaudernack, Handroanthus impetiginosus, Hayflick limit, HBx, HeLa, Helenalin, Heterogeneous ribonucleoprotein particle, Homologous recombination, HTR, ..., Idiopathic pulmonary fibrosis, Immortalised cell line, Immortality, In vitro compartmentalization, Index of genetics articles, Induced pluripotent stem cell, Induced stem cells, Isogenic human disease models, Isotretinoin, Judith Campisi, Juli Feigon, Karen Beemon, Killifish, KLF4, LANA, Life extension, List of Australian Nobel laureates, List of geneticists, List of MeSH codes (D08), List of Nobel laureates in Physiology or Medicine, List of Russian biologists, List of Russian people, List of Russian physicians and psychologists, List of Russian scientists, List of University of California, Berkeley alumni, List of Wesleyan University people, Lobster, LSm, María Blasco Marhuenda, Mary-Lou Pardue, Medical genetics of Jews, Mesothelioma, Michael D. West, Michael Fossel, Microcell-mediated chromosome transfer, Mitochondrial DNA, Mouse-eared bat, Muse cell, Nobel Prize in Physiology or Medicine, Non-coding RNA, Nucleic acid secondary structure, Nucleoprotein, Pancreatic neuroendocrine tumor, Papillomaviridae, Patent Lens, Pediatric ependymoma, Physiology, PIF1 5'-to-3' DNA helicase, PINX1, Planarian, Polysomy, POT1, Protein subunit, Rejuvenation (aging), Reptin, Reverse transcriptase, Richard Lounsbery Award, RNA, RNA world, RNA-dependent RNA polymerase, Senescence, Senotherapeutics, Shantanu Chowdhury, Shelterin, Sierra Sciences, Small nucleolar RNA, SMG6, Subtelomere, Survival of motor neuron, Telomerase reverse transcriptase, Telomerase RNA component, Telomere-binding protein, Telomestatin, TEP1, TERF1, TERF2, TERRA (biology), Tetrahymena, The Hallmarks of Cancer, Thomas Cech, Timeline of senescence research, Timeline of women in science in the United States, Titia de Lange, Transcription (biology), Tumor antigen vaccine, United States – Israel Binational Science Foundation, University of California, Berkeley, University of California, San Francisco, Victorian Honour Roll of Women, Viral eukaryogenesis, Werner syndrome, Wharton's jelly, Wiley Prize, William H. Andrews (biologist), Xenopus, 1984 in science, 2012 in science, 2016 in science. Expand index (98 more) »

-ase

The suffix -ase is used in biochemistry to form names of enzymes.

New!!: Telomerase and -ase · See more »

ACD (gene)

Adrenocortical dysplasia protein homolog is a protein that in humans is encoded by the ACD gene.

New!!: Telomerase and ACD (gene) · See more »

Adrenocortical carcinoma

Adrenocortical carcinoma (ACC, adrenal cortical carcinoma, adrenal cortical cancer, adrenal cortex cancer, etc.) is an aggressive cancer originating in the cortex (steroid hormone-producing tissue) of the adrenal gland.

New!!: Telomerase and Adrenocortical carcinoma · See more »

Ageing

Ageing or aging (see spelling differences) is the process of becoming older.

New!!: Telomerase and Ageing · See more »

Alexey Olovnikov

Alexey Matveyevich Olovnikov (Алексей Матвеевич Оловников; born 10 October 1936 in Vladivostok, Russia) is a Russian biologist.

New!!: Telomerase and Alexey Olovnikov · See more »

Astragalus

Astragalus is a large genus of about 3,000 species of herbs and small shrubs, belonging to the legume family Fabaceae and the subfamily Faboideae.

New!!: Telomerase and Astragalus · See more »

Astragalus propinquus

Astragalus propinquus (syn. Astragalus membranaceus, commonly known as Mongolian milkvetch in English and as huáng qí, běi qí or huáng huā huáng qí, in Chinese, is a flowering plant in the family Fabaceae. It is one of the 50 fundamental herbs used in traditional Chinese medicine. It is a perennial plant and it is not listed as being threatened.

New!!: Telomerase and Astragalus propinquus · See more »

Biological immortality

Biological immortality (sometimes referred to bio-indefinite mortality) is a state in which the rate of mortality from senescence is stable or decreasing, thus decoupling it from chronological age.

New!!: Telomerase and Biological immortality · See more »

Bloomberg Distinguished Professorships

Bloomberg Distinguished Professorships (BDPs) were established as part of a $350 million gift by Michael Bloomberg, JHU Class of 1964, to Johns Hopkins University in 2013.

New!!: Telomerase and Bloomberg Distinguished Professorships · See more »

Bryant Villeponteau

Bryant Villeponteau is an American scientist, entrepreneur, and longevity expert who has worked in both academia and industry.

New!!: Telomerase and Bryant Villeponteau · See more »

Cajal body

Cajal bodies (CBs) also coiled bodies, are spherical sub-organelles of 0.3–1.0 µm in diameter found in the nucleus of proliferative cells like embryonic cells and tumor cells, or metabolically active cells like neurons.

New!!: Telomerase and Cajal body · See more »

Cancer stem cell

Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample.

New!!: Telomerase and Cancer stem cell · See more »

Carcinogenesis

Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells.

New!!: Telomerase and Carcinogenesis · See more »

Carol W. Greider

Carolyn Widney "Carol" Greider (born April 15, 1961) is an American molecular biologist.

New!!: Telomerase and Carol W. Greider · See more »

Cell culture

Cell culture is the process by which cells are grown under controlled conditions, generally outside their natural environment.

New!!: Telomerase and Cell culture · See more »

Cell division

Cell division is the process by which a parent cell divides into two or more daughter cells.

New!!: Telomerase and Cell division · See more »

Cerebroretinal microangiopathy with calcifications and cysts

Cerebroretinal microangiopathy with calcifications and cysts (CRMCC) is a rare genetic disorder, which affects multiple organs.

New!!: Telomerase and Cerebroretinal microangiopathy with calcifications and cysts · See more »

Child abuse

Child abuse or child maltreatment is physical, sexual, or psychological maltreatment or neglect of a child or children, especially by a parent or other caregiver.

New!!: Telomerase and Child abuse · See more »

Cladonia furcata

Cladonia furcata is a species of lichen in the family Cladoniaceae.

New!!: Telomerase and Cladonia furcata · See more »

Clone (cell biology)

A clone is a group of identical cells that share a common ancestry, meaning they are derived from the same cell.

New!!: Telomerase and Clone (cell biology) · See more »

Complex systems biology

Complex systems biology (CSB) is a branch or subfield of mathematical and theoretical biology concerned with complexity of both structure and function in biological organisms, as well as the emergence and evolution of organisms and species, with emphasis being placed on the complex interactions of, and within, bionetworks, and on the fundamental relations and relational patterns that are essential to life.

New!!: Telomerase and Complex systems biology · See more »

CST Complex

The CST Complex is a cellular multiprotein complex that in budding yeast (Saccharomyces cerevisiae) is composed of the proteins Cdc13, Stn1, and Ten1, whereas in mammals the CST Complex consists of the proteins CTC1, STN1, and TEN1.

New!!: Telomerase and CST Complex · See more »

Cycloastragenol

Cycloastragenol is a molecule isolated from various species in the genus Astragalus that is purported to have telomerase activation activity.

New!!: Telomerase and Cycloastragenol · See more »

Darwin Awards

The Darwin Awards are a tongue-in-cheek honor, originating in Usenet newsgroup discussions around 1985.

New!!: Telomerase and Darwin Awards · See more »

DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

New!!: Telomerase and DNA · See more »

DNA polymerase

DNA polymerases are enzymes that synthesize DNA molecules from deoxyribonucleotides, the building blocks of DNA.

New!!: Telomerase and DNA polymerase · See more »

DNA replication

In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.

New!!: Telomerase and DNA replication · See more »

DNA-binding domain

A DNA-binding domain (DBD) is an independently folded protein domain that contains at least one structural motif that recognizes double- or single-stranded DNA.

New!!: Telomerase and DNA-binding domain · See more »

Elizabeth Blackburn

Elizabeth Helen Blackburn, (born 26 November 1948) is an Australian-American Nobel laureate who is currently the President of the Salk Institute for Biological Studies.

New!!: Telomerase and Elizabeth Blackburn · See more »

Embryonic stem cell

Embryonic stem cells (ES cells or ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre-implantation embryo.

New!!: Telomerase and Embryonic stem cell · See more »

Endothelial colony forming cell

Endothelial colony forming cells (or ECFCs) are adult endothelial progenitor cells capable of differentiating to regenerate endothelial cell populations.

New!!: Telomerase and Endothelial colony forming cell · See more »

Epithelioid sarcoma

Epithelioid sarcoma is a rare soft tissue sarcoma arising from mesenchymal tissue and characterized by epithelioid-like features.

New!!: Telomerase and Epithelioid sarcoma · See more »

Eternal youth

Eternal youth is the concept of human physical immortality free of ageing.

New!!: Telomerase and Eternal youth · See more »

Eukaryotic DNA replication

Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to once per cell cycle.

New!!: Telomerase and Eukaryotic DNA replication · See more »

Experimental cancer treatment

Experimental cancer treatments are medical therapies intended or claimed to treat cancer by improving on, supplementing or replacing conventional methods (surgery, chemotherapy, radiation, and immunotherapy).

New!!: Telomerase and Experimental cancer treatment · See more »

Frederick Sanger

Frederick Sanger (13 August 1918 – 19 November 2013) was a British biochemist who twice won the Nobel Prize in Chemistry, one of only two people to have done so in the same category (the other is John Bardeen in physics), the fourth person overall with two Nobel Prizes, and the third person overall with two Nobel Prizes in the sciences.

New!!: Telomerase and Frederick Sanger · See more »

G-quadruplex

In molecular biology, G-quadruplex secondary structures are formed in nucleic acids by sequences that are rich in guanine.

New!!: Telomerase and G-quadruplex · See more »

Gambogic acid

Gambogic acid is a xanthonoid that is derived from the brownish or orange resin from Garcinia hanburyi.

New!!: Telomerase and Gambogic acid · See more »

Genome (book)

Genome: The Autobiography of a Species in 23 Chapters is a 1999 popular science book by the science writer Matt Ridley, published by Fourth Estate.

New!!: Telomerase and Genome (book) · See more »

Germline

In biology and genetics, the germline in a multicellular organism is the population of its bodily cells that are so differentiated or segregated that in the usual processes of reproduction they may pass on their genetic material to the progeny.

New!!: Telomerase and Germline · See more »

Geron Corporation

Geron Corporation is a biotechnology company located in Menlo Park, California, which specializes in developing and commercializing therapeutic products for cancer that inhibit telomerase.

New!!: Telomerase and Geron Corporation · See more »

Gustav Gaudernack

Professor Gustav Gaudernack is one of the leading scientists in the development of cancer vaccines and cancer immunotherapy.

New!!: Telomerase and Gustav Gaudernack · See more »

Handroanthus impetiginosus

Handroanthus impetiginosus, pink ipê, pink lapacho, or pink trumpet tree is a native tree of family Bignoniaceae of the Americas, distributed from northern Mexico south to northern Argentina.

New!!: Telomerase and Handroanthus impetiginosus · See more »

Hayflick limit

The Hayflick limit or Hayflick phenomenon is the number of times a normal human cell population will divide before cell division stops.

New!!: Telomerase and Hayflick limit · See more »

HBx

HBx is a hepatitis B viral protein.

New!!: Telomerase and HBx · See more »

HeLa

HeLa (also Hela or hela) is a cell type in an immortal cell line used in scientific research.

New!!: Telomerase and HeLa · See more »

Helenalin

Helenalin, or(±)-4-Hydroxy-4a,8-dimethyl-3,3a,4a,7a,8,9,9a-octahydroazulenofuran-2,5-dione, is a toxic sesquiterpene lactone which can be found in several plants such as Arnica montana and Arnica chamissonis subsp.

New!!: Telomerase and Helenalin · See more »

Heterogeneous ribonucleoprotein particle

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are complexes of RNA and protein present in the cell nucleus during gene transcription and subsequent post-transcriptional modification of the newly synthesized RNA (pre-mRNA).

New!!: Telomerase and Heterogeneous ribonucleoprotein particle · See more »

Homologous recombination

Homologous recombination is a type of genetic recombination in which nucleotide sequences are exchanged between two similar or identical molecules of DNA.

New!!: Telomerase and Homologous recombination · See more »

HTR

HTR may refer to.

New!!: Telomerase and HTR · See more »

Idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a type of chronic lung disease characterized by a progressive and irreversible decline in lung function.

New!!: Telomerase and Idiopathic pulmonary fibrosis · See more »

Immortalised cell line

An immortalized cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division.

New!!: Telomerase and Immortalised cell line · See more »

Immortality

Immortality is eternal life, being exempt from death, unending existence.

New!!: Telomerase and Immortality · See more »

In vitro compartmentalization

In vitro compartmentalization (IVC) is an emulsion-based technology that generates cell-like compartments in vitro.

New!!: Telomerase and In vitro compartmentalization · See more »

Index of genetics articles

Genetics (from Ancient Greek γενετικός genetikos, “genite” and that from γένεσις genesis, “origin”), a discipline of biology, is the science of heredity and variation in living organisms.

New!!: Telomerase and Index of genetics articles · See more »

Induced pluripotent stem cell

Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from adult cells.

New!!: Telomerase and Induced pluripotent stem cell · See more »

Induced stem cells

Induced stem cells (iSC) are stem cells derived from somatic, reproductive, pluripotent or other cell types by deliberate epigenetic reprogramming.

New!!: Telomerase and Induced stem cells · See more »

Isogenic human disease models

Isogenic human disease models are a family of cells that are selected or engineered to accurately model the genetics of a specific patient population, in vitro.

New!!: Telomerase and Isogenic human disease models · See more »

Isotretinoin

Isotretinoin, also known as 13-cis-retinoic acid (and colloquially referred to by its former brand name Accutane or Roaccutane), is a medication primarily used to treat severe acne.

New!!: Telomerase and Isotretinoin · See more »

Judith Campisi

Judith Campisi is a professor of biogerontology at the Buck Institute for Research on Aging.

New!!: Telomerase and Judith Campisi · See more »

Juli Feigon

Juli Feigon is a Distinguished Professor of Biochemistry at the University of California, Los Angeles, where she has been a faculty member since 1985.

New!!: Telomerase and Juli Feigon · See more »

Karen Beemon

Karen Beemon is an American molecular biologist whose research focuses primarily on viruses, RNA, and the genetic causes of cancer.

New!!: Telomerase and Karen Beemon · See more »

Killifish

A killifish is any of various oviparous (egg-laying) cyprinodontiform fish (including families Aplocheilidae, Cyprinodontidae, Fundulidae, Profundulidae and Valenciidae).

New!!: Telomerase and Killifish · See more »

KLF4

Kruppel-like factor 4 (KLF4; gut-enriched Krüppel-like factor or GKLF) is a zinc-finger transcription factor, and it was first identified in 1996.

New!!: Telomerase and KLF4 · See more »

LANA

The latency-associated nuclear antigen (LANA-1) or latent nuclear antigen (LNA, LNA-1), is a Kaposi's sarcoma-associated herpesvirus (KSHV) latent protein initially found by Moore and colleagues as a speckled nuclear antigen present in primary effusion lymphoma cells that reacts with antibodies from patients with KS.

New!!: Telomerase and LANA · See more »

Life extension

Life extension science, also known as anti-aging medicine, indefinite life extension, experimental gerontology, and biomedical gerontology, is the study of slowing down or reversing the processes of aging to extend both the maximum and average lifespan.

New!!: Telomerase and Life extension · See more »

List of Australian Nobel laureates

Since 1915 there have been sixteen Australian winners of the Nobel Prize.

New!!: Telomerase and List of Australian Nobel laureates · See more »

List of geneticists

This is a list of people who have made notable contributions to genetics.

New!!: Telomerase and List of geneticists · See more »

List of MeSH codes (D08)

This is the fourth part of the list of the "D" codes for MeSH.

New!!: Telomerase and List of MeSH codes (D08) · See more »

List of Nobel laureates in Physiology or Medicine

The Nobel Prize in Physiology or Medicine (Nobelpriset i fysiologi eller medicin) is awarded annually by the Swedish Karolinska Institute to scientists and doctors in the various fields of physiology or medicine.

New!!: Telomerase and List of Nobel laureates in Physiology or Medicine · See more »

List of Russian biologists

This list of Russian biologists includes the famous biologists from the Russian Federation, the Soviet Union, the Russian Empire and other predecessor states of Russia.

New!!: Telomerase and List of Russian biologists · See more »

List of Russian people

This is a list of people associated with the modern Russian Federation, the Soviet Union, Imperial Russia, Russian Tsardom, the Grand Duchy of Moscow, and other predecessor states of Russia.

New!!: Telomerase and List of Russian people · See more »

List of Russian physicians and psychologists

This list of Russian physicians and psychologists includes the famous physicians and psychologists, medical scientists and medical doctors from the Russian Federation, the Soviet Union, the Russian Empire and other predecessor states of Russia.

New!!: Telomerase and List of Russian physicians and psychologists · See more »

List of Russian scientists

Alona Soschen.

New!!: Telomerase and List of Russian scientists · See more »

List of University of California, Berkeley alumni

This page lists notable alumni and students of the University of California, Berkeley.

New!!: Telomerase and List of University of California, Berkeley alumni · See more »

List of Wesleyan University people

This is a partial list of notable people affiliated with Wesleyan University.

New!!: Telomerase and List of Wesleyan University people · See more »

Lobster

Lobsters comprise a family (Nephropidae, sometimes also Homaridae) of large marine crustaceans.

New!!: Telomerase and Lobster · See more »

LSm

In molecular biology, LSm proteins are a family of RNA-binding proteins found in virtually every cellular organism.

New!!: Telomerase and LSm · See more »

María Blasco Marhuenda

María Antonia Blasco Marhuenda (born 1965), known as María Blasco, is a Spanish molecular biologist.

New!!: Telomerase and María Blasco Marhuenda · See more »

Mary-Lou Pardue

Mary-Lou Pardue is an American geneticist who is an emeritus professor in the Department of Biology at the Massachusetts Institute of Technology, which she originally joined in 1972.

New!!: Telomerase and Mary-Lou Pardue · See more »

Medical genetics of Jews

The medical genetics of Jews is the study, screening, and treatment of genetic disorders more common in particular Jewish populations than in the population as a whole.

New!!: Telomerase and Medical genetics of Jews · See more »

Mesothelioma

Mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the internal organs (known as the mesothelium).

New!!: Telomerase and Mesothelioma · See more »

Michael D. West

Michael D. West is a gerontologist, and a pioneer in stem cells, cellular aging and telomerase.

New!!: Telomerase and Michael D. West · See more »

Michael Fossel

Michael B. Fossel, M.D., Ph.D. (born 1950, Greenwich, Connecticut) was a professor of clinical medicine at Michigan State University and is the author of several books on aging, who is best known for his views on telomerase therapy as a possible treatment for cellular senescence.

New!!: Telomerase and Michael Fossel · See more »

Microcell-mediated chromosome transfer

Microcell Mediated Chromosome Transfer (or MMCT) is a technique used in cell biology and genetics to transfer a chromosome from a defined donor cell line into a recipient cell line.

New!!: Telomerase and Microcell-mediated chromosome transfer · See more »

Mitochondrial DNA

Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, adenosine triphosphate (ATP).

New!!: Telomerase and Mitochondrial DNA · See more »

Mouse-eared bat

The mouse-eared bats (Myotis) are a diverse and widespread genus of bats within the family Vespertilionidae.

New!!: Telomerase and Mouse-eared bat · See more »

Muse cell

A muse cell (multi-lineage differentiating stress enduring cell) is a endogenous non-tumorigenic pluripotent stem cell.

New!!: Telomerase and Muse cell · See more »

Nobel Prize in Physiology or Medicine

The Nobel Prize in Physiology or Medicine (Nobelpriset i fysiologi eller medicin), administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the fields of life sciences and medicine.

New!!: Telomerase and Nobel Prize in Physiology or Medicine · See more »

Non-coding RNA

A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein.

New!!: Telomerase and Non-coding RNA · See more »

Nucleic acid secondary structure

Nucleic acid secondary structure is the basepairing interactions within a single nucleic acid polymer or between two polymers.

New!!: Telomerase and Nucleic acid secondary structure · See more »

Nucleoprotein

Nucleoproteins are any proteins that are structurally associated with nucleic acids, either DNA or RNA.

New!!: Telomerase and Nucleoprotein · See more »

Pancreatic neuroendocrine tumor

Pancreatic neuroendocrine tumors (PanNETs, PETs, or PNETs), often referred to as "islet cell tumors", or "pancreatic endocrine tumors" are neuroendocrine neoplasms that arise from cells of the endocrine (hormonal) and nervous system within the pancreas.

New!!: Telomerase and Pancreatic neuroendocrine tumor · See more »

Papillomaviridae

Papillomaviridae is an ancient taxonomic family of non-enveloped DNA viruses, collectively known as papillomaviruses.

New!!: Telomerase and Papillomaviridae · See more »

Patent Lens

The Patent Lens was an online patent search facility and knowledge resource, provided by CAMBIA, an independent, international non-profit organization dedicated to democratizing innovation.

New!!: Telomerase and Patent Lens · See more »

Pediatric ependymoma

Pediatric ependymomas are similar in nature to the adult form of ependymoma in that they are thought to arise from radial glial cells lining the ventricular system.

New!!: Telomerase and Pediatric ependymoma · See more »

Physiology

Physiology is the scientific study of normal mechanisms, and their interactions, which work within a living system.

New!!: Telomerase and Physiology · See more »

PIF1 5'-to-3' DNA helicase

PIF1 5'-to-3' DNA helicase is a protein that in humans is encoded by the PIF1 gene.

New!!: Telomerase and PIF1 5'-to-3' DNA helicase · See more »

PINX1

PIN2/TERF1-interacting telomerase inhibitor 1, also known as PINX1, is a human gene.

New!!: Telomerase and PINX1 · See more »

Planarian

A planarian is one of many flatworms of the Turbellaria class.

New!!: Telomerase and Planarian · See more »

Polysomy

Polysomy is a condition found in many species, including fungi, plants, insects, and mammals, in which an organism has at least one more chromosome than normal, i.e., there may be three or more copies of the chromosome rather than the expected two copies.

New!!: Telomerase and Polysomy · See more »

POT1

Protection of telomeres protein 1 is a protein that in humans is encoded by the POT1 gene.

New!!: Telomerase and POT1 · See more »

Protein subunit

In structural biology, a protein subunit is a single protein molecule that assembles (or "coassembles") with other protein molecules to form a protein complex.

New!!: Telomerase and Protein subunit · See more »

Rejuvenation (aging)

Rejuvenation is a medical discipline focused on the practical reversal of the aging process.

New!!: Telomerase and Rejuvenation (aging) · See more »

Reptin

Reptin is a tumor repressor protein that is a member of the ATPases Associated with various cellular Activities (AAA+) helicase family and regulates KAI1.

New!!: Telomerase and Reptin · See more »

Reverse transcriptase

A reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription.

New!!: Telomerase and Reverse transcriptase · See more »

Richard Lounsbery Award

The Richard Lounsbery Award is given to American and French scientists, 45 years or younger, in recognition of "extraordinary scientific achievement in biology and medicine." The Award alternates between French and American scientists, and is awarded by the National Academy of Sciences and the French Academy of Sciences in alternating years to a scientist from the other country.

New!!: Telomerase and Richard Lounsbery Award · See more »

RNA

Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.

New!!: Telomerase and RNA · See more »

RNA world

The RNA world is a hypothetical stage in the evolutionary history of life on Earth, in which self-replicating RNA molecules proliferated before the evolution of DNA and proteins.

New!!: Telomerase and RNA world · See more »

RNA-dependent RNA polymerase

RNA-dependent RNA polymerase (RdRP), (RDR), or RNA replicase, is an enzyme that catalyzes the replication of RNA from an RNA template.

New!!: Telomerase and RNA-dependent RNA polymerase · See more »

Senescence

Senescence or biological ageing is the gradual deterioration of function characteristic of most complex lifeforms, arguably found in all biological kingdoms, that on the level of the organism increases mortality after maturation.

New!!: Telomerase and Senescence · See more »

Senotherapeutics

Senotherapeutics is an early-stage basic research field for development of possible therapeutic agents and strategies to specifically target cellular senescence, an altered cell state associated with ageing and age-related diseases.

New!!: Telomerase and Senotherapeutics · See more »

Shantanu Chowdhury

Shantanu Chowdhury (born 1968) is an Indian structural biologist and a professor at Institute of Genomics and Integrative Biology of the Council of Scientific and Industrial Research.

New!!: Telomerase and Shantanu Chowdhury · See more »

Shelterin

Shelterin (also called telosome) is a protein complex known to protect telomeres in many eukaryotes from DNA repair mechanisms, as well as regulate telomerase activity.

New!!: Telomerase and Shelterin · See more »

Sierra Sciences

Sierra Sciences, LLC is a biotechnology company founded by William H. Andrews, former director of molecular biology at Geron Corporation.

New!!: Telomerase and Sierra Sciences · See more »

Small nucleolar RNA

Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs.

New!!: Telomerase and Small nucleolar RNA · See more »

SMG6

Telomerase-binding protein EST1A is an enzyme that in humans is encoded by the SMG6 gene on chromosome 17.

New!!: Telomerase and SMG6 · See more »

Subtelomere

Subtelomeres are segments of DNA between telomeric caps and chromatin.

New!!: Telomerase and Subtelomere · See more »

Survival of motor neuron

Survival of motor neuron or survival motor neuron (SMN) is a protein that in humans is encoded by the SMN1 and SMN2 genes.

New!!: Telomerase and Survival of motor neuron · See more »

Telomerase reverse transcriptase

Telomerase reverse transcriptase (abbreviated to TERT, or hTERT in humans) is a catalytic subunit of the enzyme telomerase, which, together with the telomerase RNA component (TERC), comprises the most important unit of the telomerase complex.

New!!: Telomerase and Telomerase reverse transcriptase · See more »

Telomerase RNA component

| Name.

New!!: Telomerase and Telomerase RNA component · See more »

Telomere-binding protein

Telomere-binding proteins (also known as TERF, TRBF, TRF) function to bind telomeric DNA in various species.

New!!: Telomerase and Telomere-binding protein · See more »

Telomestatin

Telomestatin is a macrocyclic chemical compound that acts by inhibiting the telomerase activity of in vitro cancer cells.

New!!: Telomerase and Telomestatin · See more »

TEP1

Telomerase protein component 1 is an enzyme that in humans is encoded by the TEP1 gene.

New!!: Telomerase and TEP1 · See more »

TERF1

Telomeric repeat-binding factor 1 is a protein that in humans is encoded by the TERF1 gene.

New!!: Telomerase and TERF1 · See more »

TERF2

Telomeric repeat-binding factor 2 is a protein that is present at telomeres throughout the cell cycle.

New!!: Telomerase and TERF2 · See more »

TERRA (biology)

TERRA in biology is an abbreviation for "TElomeric Repeat-containing RNA".

New!!: Telomerase and TERRA (biology) · See more »

Tetrahymena

Tetrahymena is a genus of free-living ciliates that can also switch from commensalistic to pathogenic modes of survival.

New!!: Telomerase and Tetrahymena · See more »

The Hallmarks of Cancer

"The Hallmarks of Cancer" is a seminal peer-reviewed article published in the journal Cell in January 2000 by the cancer researchers Douglas Hanahan and Robert Weinberg.

New!!: Telomerase and The Hallmarks of Cancer · See more »

Thomas Cech

Thomas Robert Cech (born December 8, 1947) is an American chemist who shared the 1989 Nobel Prize in Chemistry with Sidney Altman, for their discovery of the catalytic properties of RNA.

New!!: Telomerase and Thomas Cech · See more »

Timeline of senescence research

This page is a timeline of senescence research, including major theories, breakthroughs and organizations.

New!!: Telomerase and Timeline of senescence research · See more »

Timeline of women in science in the United States

This is a timeline of women in science in the United States.

New!!: Telomerase and Timeline of women in science in the United States · See more »

Titia de Lange

Titia de Lange (born 11 November 1955, in Rotterdam) is an American Cancer Society professor and head of Laboratory Cell Biology and Genetics at Rockefeller University.

New!!: Telomerase and Titia de Lange · See more »

Transcription (biology)

Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.

New!!: Telomerase and Transcription (biology) · See more »

Tumor antigen vaccine

According to the National Cancer Institute, a tumor antigen vaccine is a "vaccine made of cancer cells, parts of cancer cells, or pure tumor antigens (substances isolated from tumor cells)".

New!!: Telomerase and Tumor antigen vaccine · See more »

United States – Israel Binational Science Foundation

The United States-Israel Binational Science Foundation (BSF) is a grant-awarding institution that promotes collaborative research in a wide range of basic and applied scientific disciplines, established in 1972 by an agreement between the governments of the United States and Israel.

New!!: Telomerase and United States – Israel Binational Science Foundation · See more »

University of California, Berkeley

The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public research university in Berkeley, California.

New!!: Telomerase and University of California, Berkeley · See more »

University of California, San Francisco

The University of California, San Francisco (UCSF), is a research university located in San Francisco, California and part of the University of California system.

New!!: Telomerase and University of California, San Francisco · See more »

Victorian Honour Roll of Women

The Victorian Honour Roll of Women was established in 2001 to recognise the achievements of women from the Australian state of Victoria.

New!!: Telomerase and Victorian Honour Roll of Women · See more »

Viral eukaryogenesis

Viral eukaryogenesis is the hypothesis that the cell nucleus of eukaryotic life forms evolved from a large DNA virus in a form of endosymbiosis within a methanogenic archaeon.

New!!: Telomerase and Viral eukaryogenesis · See more »

Werner syndrome

Werner syndrome (WS), also known as "adult progeria",James, William; Berger, Timothy; Elston, Dirk (2005).

New!!: Telomerase and Werner syndrome · See more »

Wharton's jelly

Wharton's jelly (substantia gelatinea funiculi umbilicalis) is a gelatinous substance within the umbilical cord also present in vitreous humor of the eyeball, largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate).

New!!: Telomerase and Wharton's jelly · See more »

Wiley Prize

The Wiley Prize in Biomedical Sciences is intended to recognize breakthrough research in pure or applied life science research that is distinguished by its excellence, originality and impact on our understanding of biological systems and processes.

New!!: Telomerase and Wiley Prize · See more »

William H. Andrews (biologist)

William Henry Andrews, Ph.D. (born December 10, 1951) is an American molecular biologist and gerontologist whose career has centered on searching for a cure for human aging.

New!!: Telomerase and William H. Andrews (biologist) · See more »

Xenopus

Xenopus (Gk., ξενος, xenos.

New!!: Telomerase and Xenopus · See more »

1984 in science

The year 1984 in science and technology involved some significant events.

New!!: Telomerase and 1984 in science · See more »

2012 in science

The year 2012 involved many significant scientific events and discoveries, including the first orbital rendezvous by a commercial spacecraft, the discovery of a particle highly similar to the long-sought Higgs boson, and the near-eradication of guinea worm disease.

New!!: Telomerase and 2012 in science · See more »

2016 in science

A number of significant scientific events occurred in 2016.

New!!: Telomerase and 2016 in science · See more »

Redirects here:

Telomerisation, Telomerisation reaction.

References

[1] https://en.wikipedia.org/wiki/Telomerase

OutgoingIncoming
Hey! We are on Facebook now! »