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Vitamin K antagonist

Index Vitamin K antagonist

Vitamin K antagonists (VKA) are a group of substances that reduce blood clotting by reducing the action of vitamin K. They are used as anticoagulant medications in the prevention of thrombosis, and in pest control, as rodenticides. [1]

34 relations: AVK, Brodifacoum, Bromadiolone, Clorindione, Coumarin, Coumatetralyl, Deep vein thrombosis, Difenacoum, Diphenadione, Discovery and development of direct thrombin inhibitors, Edoxaban, Flocoumafen, Fluindione, Heparin-induced thrombocytopenia, Leaf vegetable, Lornoxicam, Methylphenidate, Phenindione, Phenprocoumon, Phenylbutazone, Prothrombin complex concentrate, Rivaroxaban, SAMe-TT2R2 score, Silver sulfadiazine, Superficial vein thrombosis, Superwarfarin, Tecarfarin, Thrombosis, Tioclomarol, Vitamin K2, VKA, Warfarin necrosis, 1,3-Indandione, 4-Hydroxycoumarins.

AVK

AVK may refer to.

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Brodifacoum

Brodifacoum is a highly lethal 4-hydroxycoumarin vitamin K antagonist anticoagulant poison.

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Bromadiolone

Bromadiolone is a potent anticoagulant rodenticide.

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Clorindione

Clorindione is a vitamin K antagonist.

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Coumarin

Coumarin (2H-chromen-2-one) is a fragrant organic chemical compound in the benzopyrone chemical class, although it may also be seen as a subclass of lactones.

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Coumatetralyl

Coumatetralyl is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type used as a rodenticide.

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Deep vein thrombosis

Deep vein thrombosis (DVT), is the formation of a blood clot in a deep vein, most commonly the legs.

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Difenacoum

Difenacoum is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type.

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Diphenadione

Diphenadione is a vitamin K antagonist that has anticoagulant effects and is used as a rodenticide against rats, mice, voles, ground squirrels and other rodents.

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Discovery and development of direct thrombin inhibitors

Direct thrombin inhibitors (DTIs) are a class of anticoagulant drugs that can be used to prevent and treat embolisms and blood clots caused by various diseases.

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Edoxaban

Edoxaban (DU-176b, trade names Savaysa, Lixiana) is an oral anticoagulant drug which acts as a direct factor Xa inhibitor.

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Flocoumafen

Flocoumafen is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type.

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Fluindione

Fluindione is a vitamin K antagonist.

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Heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant.

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Leaf vegetable

Leaf vegetables, also called leafy greens, salad greens, pot herbs, vegetable greens, or simply greens, are plant leaves eaten as a vegetable, sometimes accompanied by tender petioles and shoots.

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Lornoxicam

Lornoxicam (INN, or chlortenoxicam; trade name Xefo, among others) is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic (pain relieving), anti-inflammatory and antipyretic (fever reducing) properties.

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Methylphenidate

Methylphenidate, sold under various trade names, Ritalin being one of the most commonly known, is a central nervous system (CNS) stimulant of the phenethylamine and piperidine classes that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.

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Phenindione

Phenindione is an anticoagulant which functions as a Vitamin K antagonist.

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Phenprocoumon

Phenprocoumon (marketed under the brand names Marcoumar, Marcumar and Falithrom) is a long-acting oral anticoagulant drug, a derivative of coumarin.

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Phenylbutazone

Phenylbutazone, often referred to as "bute," is a nonsteroidal anti-inflammatory drug (NSAID) for the short-term treatment of pain and fever in animals.

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Prothrombin complex concentrate

Prothrombin complex concentrate (PCC), also known as factor IX complex, is a medication made up of blood clotting factors II, IX, and X. Some versions also contain factor VII.

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Rivaroxaban

Rivaroxaban, sold under the brand name Xarelto, among others, is an oral anticoagulant medication (blood thinner).

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SAMe-TT2R2 score

The SAMe-TT2R2 score is a clinical prediction rule to predict the quality of vitamin K antagonist anticoagulation therapy as measured by time in therapeutic INR range (TTR) (VKA e.g. warfarin).

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Silver sulfadiazine

Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent infection.

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Superficial vein thrombosis

Superficial vein thrombosis (SVT) is a type blood clot in a vein, which forms in a superficial vein near the surface of the body.

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Superwarfarin

Superwarfarins are highly potent vitamin K antagonist anticoagulants that are used as rodenticides.

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Tecarfarin

Tecarfarin is a vitamin K antagonist under development for use as an anticoagulant.

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Thrombosis

Thrombosis (from Ancient Greek θρόμβωσις thrómbōsis "clotting”) is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.

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Tioclomarol

Tioclomarol is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type.

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Vitamin K2

Vitamin K2 or menaquinone has nine related compounds, generally subdivided into the short-chain menaquinones (with MK-4 as the most important member) and the long-chain menaquinones, of which MK-7, MK-8 and MK-9 are nutritionally the most recognized.

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VKA

VKA may refer to.

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Warfarin necrosis

Warfarin-induced skin necrosis (or, more generally, Anticoagulant-induced skin necrosis) is a condition in which skin and subcutaneous tissue necrosis (tissue death) occurs due to acquired protein C deficiency following treatment with anti-vitamin K anticoagulants (4-hydroxycoumarins, such as warfarin).

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1,3-Indandione

1,3-Indandione (indanedione) is an organic compound with the molecular formula C9H6O2.

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4-Hydroxycoumarins

4-Hydroxycoumarins belong to a class of vitamin K antagonist (VKA) anticoagulant drug molecules derived from coumarin by adding a hydroxy group at the 4 position to obtain 4-hydroxycoumarin, then adding a large aromatic substituent at the 3-position (the ring-carbon between the hydroxyl and the carbonyl).

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Redirects here:

Anti-vitamin K, Antivitamin K, Vitamin K antagonists.

References

[1] https://en.wikipedia.org/wiki/Vitamin_K_antagonist

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