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Zafirlukast

Index Zafirlukast

Zafirlukast is an orally administered leukotriene receptor antagonist (LTRA) used for the chronic treatment of asthma. [1]

27 relations: Accolade (disambiguation), Antileukotriene, Arachidonate 5-lipoxygenase, Aspirin-induced asthma, Asthma, AstraZeneca, ATC code R03, Breast augmentation, Breast implant, Capsular contracture, CYP2C9, Cysteinyl leukotriene receptor 1, Cysteinyl leukotriene receptor 2, Drug interaction, Drug nomenclature, Eicosanoid, Leukotriene, Leukotriene D4, List of cytochrome P450 modulators, List of drugs: Ac, List of drugs: V-Ve, List of drugs: Z, Mast cell, Primidone, Respiratory Pharmacology, Structural scheduling of synthetic cannabinoids, Zileuton.

Accolade (disambiguation)

Accolade is a ceremony to confer knighthood.

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Antileukotriene

An antileukotriene is a drug which functions as a leukotriene-related enzyme inhibitor (arachidonate 5-lipoxygenase) or leukotriene receptor antagonist (cysteinyl leukotriene receptors) and consequently opposes the function of these inflammatory mediators; leukotrienes are produced by the immune system and serve to promote bronchoconstriction, inflammation, microvascular permeability, and mucus secretion in asthma and COPD.

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Arachidonate 5-lipoxygenase

Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is a non-heme iron-containing enzyme (EC 1.13.11.34) that in humans is encoded by the ALOX5 gene.

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Aspirin-induced asthma

Aspirin-induced asthma, also termed Samter's triad, Samter's syndrome, aspirin-exacerbated respiratory disease (AERD), and recently, by an appointed task force of the European Academy of Allergy and Clinical Immunology/World Allergy Organization (EAACI/WAO), Nonsteroidal anti-inflammatory drugs-exacerbated respiratory disease (N-ERD).

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Asthma

Asthma is a common long-term inflammatory disease of the airways of the lungs.

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AstraZeneca

AstraZeneca plc is an Anglo–Swedish multinational pharmaceutical and biopharmaceutical company.

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ATC code R03

R03AK Adrenergics in combination with corticosteroids or other drugs, excl.

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Breast augmentation

Breast augmentation and augmentation mammoplasty (colloquially known as a "boob job") are plastic surgery terms for the breast-implant and the fat-graft mammoplasty approaches used to increase the size, change the shape, and alter the texture of the breasts of a woman.

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Breast implant

A breast implant is a prosthesis used to change the size, shape, and contour of a woman’s breast.

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Capsular contracture

Capsular contracture is a response of the immune system to foreign materials in the human body.

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CYP2C9

Cytochrome P450 2C9 (abbreviated CYP2C9) is an enzyme that in humans is encoded by the CYP2C9 gene.

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Cysteinyl leukotriene receptor 1

Cysteinyl leukotriene receptor 1, also termed CYSLTR1, is a receptor for cysteinyl leukotrienes (LT) (see leukotrienes#Cysteinyl leukotrienes).

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Cysteinyl leukotriene receptor 2

Cysteinyl leukotriene receptor 2, also termed CYSLTR2, is a receptor for cysteinyl leukotrienes (LT) (see leukotrienes#Cysteinyl leukotrienes).

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Drug interaction

A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together.

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Drug nomenclature

Drug nomenclature is the systematic naming of drugs, especially pharmaceutical drugs.

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Eicosanoid

Eicosanoids are signaling molecules made by the enzymatic or non-enzymatic oxidation of arachidonic acid or other polyunsaturated fatty acids (PUFAs) that are, similar to arachidonic acid, 20 carbon units in length.

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Leukotriene

Leukotrienes are a family of eicosanoid inflammatory mediators produced in leukocytes by the oxidation of arachidonic acid (AA) and the essential fatty acid eicosapentaenoic acid (EPA) by the enzyme arachidonate 5-lipoxygenase.

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Leukotriene D4

Leukotriene D4 (LTD4) is one of the leukotrienes.

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List of cytochrome P450 modulators

This is a list of cytochrome P450 modulators, or inhibitors and inducers of cytochrome P450 enzymes.

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List of drugs: Ac

No description.

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List of drugs: V-Ve

No description.

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List of drugs: Z

No description.

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Mast cell

A mast cell (also known as a mastocyte or a labrocyte) is a type of white blood cell.

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Primidone

Primidone (INN, BAN, USP) is an anticonvulsant of the barbiturate class.

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Respiratory Pharmacology

There are several categories of respiratory drugs, each specific to a drug's purpose and mode of action.

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Structural scheduling of synthetic cannabinoids

To combat the illicit synthetic cannabinoid industry many jurisdictions have created a system to control these cannabinoids through their general (or Markush) structure as opposed to their specific identity (or "street name").

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Zileuton

Zileuton (trade name ZYFLO) is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation, used for the maintenance treatment of asthma.

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Redirects here:

ATC code R03DC01, ATCvet code QR03DC01, Accolate, Accoleit, Vanticon.

References

[1] https://en.wikipedia.org/wiki/Zafirlukast

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