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Ziprasidone

Index Ziprasidone

Ziprasidone, sold under the brand name Geodon among others, is an atypical antipsychotic which is used for the treatment of schizophrenia as well as acute mania and mixed states associated with bipolar disorder. [1]

83 relations: Akathisia, Alpha-1A adrenergic receptor, Alpha-2 adrenergic receptor, Amisulpride, Amitriptyline/perphenazine, Amoxapine, Antipsychotic, Aripiprazole, Asenapine, ATC code N05, Atypical antipsychotic, Borderline personality disorder, Chlorpromazine, Controversy surrounding psychiatry, CYP3A4, Dopamine antagonist, Dopaminergic, Drug-induced QT prolongation, Ethics in pharmaceutical sales, Extrapyramidal symptoms, F-15063, Fluvoxamine, Haloperidol, Heath High School shooting, Iloperidone, Intractable pain, Intrusive thought, Isothiazole, List of adrenergic drugs, List of adverse effects of risperidone, List of antipsychotics, List of dopaminergic drugs, List of drugs: G, List of drugs: Z, List of largest civil only pharmaceutical settlements, List of largest pharmaceutical settlements, List of off-label promotion pharmaceutical settlements, List of psychiatric medications, List of psychiatric medications by condition treated, List of psychotropic medications, Long QT syndrome, Lurasidone, Management of Parkinson's disease, Management of schizophrenia, Mania, Mixed affective state, Mood stabilizer, Muscarinic antagonist, Neuroleptic malignant syndrome, Nikki McKibbin, ..., Paliperidone, Paramedic, Paramedics in the United States, Pfizer, Pharmaceutical fraud, Pharmaceutical industry, Pharmaceutical marketing, Piperazine, Porphyria, Potency (pharmacology), Psychiatric medication, Psychomotor agitation, QT interval, Quetiapine, Raphael M. Bonelli, Schizoaffective disorder, Scott Weiland, Serotonin receptor agonist, Sertindole, Somnolence, Sri Siddhartha Medical College, Stefan P. Kruszewski, Suicide of Megan Meier, Texas Medication Algorithm Project, Tourette syndrome, Treatment of bipolar disorder, Treatment of Tourette syndrome, 5-HT receptor, 5-HT1A receptor, 5-HT1B receptor, 5-HT1D receptor, 5-HT2C receptor, 5-HT7 receptor. Expand index (33 more) »

Akathisia

Akathisia is a movement disorder characterized by a feeling of inner restlessness and inability to stay still.

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Alpha-1A adrenergic receptor

The alpha-1A adrenergic receptor (α1A adrenoreceptor), also known as ADRA1A, formerly known also as the alpha-1C adrenergic receptor, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it.

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Alpha-2 adrenergic receptor

The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein.

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Amisulpride

Amisulpride, sold under the brand name Solian among others, is an antipsychotic medication used to treat schizophrenia.

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Amitriptyline/perphenazine

Amitriptyline/perphenazine (Duo-Vil, Etrafon, Triavil, Triptafen) is a formulation that contains the tricyclic antidepressant amitriptyline and the medium-potency typical (first-generation) antipsychotic, perphenazine.

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Amoxapine

Amoxapine, sold under the brand name Asendin among others, is a tetracyclic antidepressant (TeCA), though it is often classified as a tricyclic antidepressant (TCA).

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Antipsychotic

Antipsychotics, also known as neuroleptics or major tranquilizers, are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder.

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Aripiprazole

Aripiprazole, sold under the brand name Abilify among others, is an atypical antipsychotic. It is recommended and primarily used in the treatment of schizophrenia and bipolar disorder. Other uses include as an add-on treatment in major depressive disorder, tic disorders, and irritability associated with autism. According to a Cochrane review, evidence for the oral form in schizophrenia is not sufficient to determine effects on general functioning. Additionally, because many people dropped out of the medication trials before they were completed, the overall strength of the conclusions is low. Side effects include neuroleptic malignant syndrome, a movement disorder known as tardive dyskinesia, and high blood sugar in those with diabetes. In the elderly there is an increased risk of death. It is thus not recommended for use in those with psychosis due to dementia. It is pregnancy category C in the United States and category C in Australia, meaning there is possible evidence of harm to the fetus. It is not recommended for women who are breastfeeding. It is unclear whether it is safe or effective in people less than 18 years old. It is a partial dopamine agonist. Aripiprazole was developed by Otsuka in Japan. In the United States, Otsuka America markets it jointly with Bristol-Myers Squibb. From April 2013 to March 2014, sales of Abilify amounted to almost $6.9 billion.

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Asenapine

Asenapine, sold under the trade names Saphris and Sycrest among others, is an atypical antipsychotic medication used to treat schizophrenia and acute mania associated with bipolar disorder.

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ATC code N05

N05.

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Atypical antipsychotic

The atypical antipsychotics (AAP; also known as second generation antipsychotics (SGAs)) are a group of antipsychotic drugs (antipsychotic drugs in general are also known as major tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) used to treat psychiatric conditions.

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Borderline personality disorder

Borderline personality disorder (BPD), also known as emotionally unstable personality disorder (EUPD), is a long-term pattern of abnormal behavior characterized by unstable relationships with other people, unstable sense of self, and unstable emotions.

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Chlorpromazine

Chlorpromazine (CPZ), marketed under the trade names Thorazine and Largactil among others, is an antipsychotic medication.

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Controversy surrounding psychiatry

As long as psychiatry has existed it has been subject to controversy.

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CYP3A4

Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.

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Dopamine antagonist

A dopamine antagonist (antidopaminergic) is a type of drug which blocks dopamine receptors by receptor antagonism.

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Dopaminergic

Dopaminergic means "related to dopamine" (literally, "working on dopamine"), dopamine being a common neurotransmitter.

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Drug-induced QT prolongation

Drug-induced QT prolongation is seen with a QT interval above 0.45 ms on the ECG and is usually a result of treatment by anti-arrhythmic drugs, such as amiodarone and sotalol, or a number of other drugs that have been reported to cause this problem (e.g., cisapride).

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Ethics in pharmaceutical sales

The ethics involved within pharmaceutical sales is built from the organizational ethics, which is a matter of system compliance, accountability and culture (Grace & Cohen, 2005).

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Extrapyramidal symptoms

Extrapyramidal symptoms (EPS), also known as extrapyramidal side effects (EPSE), are drug-induced movement disorders that include acute and tardive symptoms.

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F-15063

F-15,063 is an orally active potential antipsychotic, and an antagonist at the D2/D3 receptors, partial agonist at the D4 receptor, and agonist at the 5-HT1A receptors.

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Fluvoxamine

Fluvoxamine, sold under the brand name Luvox among others, is a medication which is used primarily for the treatment of obsessive–compulsive disorder (OCD), and is also used to treat major depressive disorder and anxiety disorders such as panic disorder and post-traumatic stress disorder.

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Haloperidol

Haloperidol, marketed under the trade name Haldol among others, is a typical antipsychotic medication.

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Heath High School shooting

The Heath High School shooting occurred at Heath High School in West Paducah, Kentucky, United States, on December 1, 1997.

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Iloperidone

Iloperidone, also known as Fanapt, Fanapta, and previously known as Zomaril, is an atypical antipsychotic for the treatment of schizophrenia.

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Intractable pain

Intractable pain, also known as Intractable Pain Disease or IP, is a severe, constant pain that is not curable by any known means and which causes a bed or house-bound state and early death if not adequately treated, usually with opioids and/or interventional procedures.

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Intrusive thought

An intrusive thought is an unwelcome involuntary thought, image, or unpleasant idea that may become an obsession, is upsetting or distressing, and can feel difficult to manage or eliminate.

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Isothiazole

An isothiazole, or 1,2-thiazole, is a type of organic compound containing a five-membered aromatic ring that consists of three carbon atoms, one nitrogen atom, and one sulfur atom.

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List of adrenergic drugs

This is a list of adrenergic drugs.

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List of adverse effects of risperidone

List of adverse effects of risperidone: Sources:Truven Health Analytics, Inc.

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List of antipsychotics

Following is a list of antipsychotics, sorted by class.

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List of dopaminergic drugs

This is a list of dopaminergic drugs.

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List of drugs: G

No description.

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List of drugs: Z

No description.

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List of largest civil only pharmaceutical settlements

The following is a list of the 21 largest civil settlements, reached between the United States Department of Justice and pharmaceutical companies from 2001 to 2017, ordered by the size of the total civil settlement.

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List of largest pharmaceutical settlements

The following is a list of the 20 largest settlements reached between the United States Department of Justice and pharmaceutical companies from 1991 to 2012, ordered by the size of the total settlement.

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List of off-label promotion pharmaceutical settlements

The following are settlements reached with US authorities against pharmaceutical companies to resolve allegations of "off-label" promotion of drugs.

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List of psychiatric medications

This is an alphabetical list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress.

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List of psychiatric medications by condition treated

This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress.

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List of psychotropic medications

List of medications which are used to treat psychiatric conditions that are on the market in the United States (this list is incomplete; the title of the entry is "List of Psychotropic Medications" and what follows is a list of psychiatric drugs - not all psychotropic agents are used to treat psychiatric conditions. A couple of examples are 'Tramadol' and 'Morphine').

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Long QT syndrome

Long QT syndrome (LQTS) is a condition which affects repolarization of the heart after a heartbeat.

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Lurasidone

Lurasidone (trade name Latuda) is an atypical antipsychotic developed by Dainippon Sumitomo Pharma and marketed by Sunovion in the U.S. It has been an FDA approved treatment for schizophrenia since 2010 and for treating depressive episodes in adults with bipolar I disorder since 2013.

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Management of Parkinson's disease

Management of Parkinson's disease (PD), due to its chronic nature, requires a broad-based program including patient and family education, support group services, general wellness maintenance, exercise, and nutrition.

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Management of schizophrenia

Management of schizophrenia usually involved many aspects including psychological, pharmacological, social, educational, and employment-related interventions directed to recovery, reducing the impact of the disease on quality of life, social functioning, and longevity.

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Mania

Mania, also known as manic syndrome, is a state of abnormally elevated arousal, affect, and energy level, or "a state of heightened overall activation with enhanced affective expression together with lability of affect." Although mania is often conceived as a "mirror image" to depression, the heightened mood can be either euphoric or irritable; indeed, as the mania intensifies, irritability can be more pronounced and result in violence, or anxiety.

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Mixed affective state

Traditionally, a mixed affective state, formerly known as a mixed-manic or mixed episode, has been defined as a state wherein features unique to both depression and mania—such as despair, fatigue, morbid or suicidal ideation, racing thoughts, pressure of activity, and heightened irritability—occur either simultaneously or in very short succession.

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Mood stabilizer

A mood stabilizer is a psychiatric pharmaceutical drug used to treat mood disorders characterized by intense and sustained mood shifts, typically bipolar disorder type I or type II, borderline personality disorder (BPD) and schizophrenia.

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Muscarinic antagonist

A muscarinic receptor antagonist (MRA) is a type of anticholinergic agent that blocks the activity of the muscarinic acetylcholine receptor.

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Neuroleptic malignant syndrome

Neuroleptic malignant syndrome (NMS) is a life-threatening reaction that occasionally occurs in response to neuroleptic or antipsychotic medication.

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Nikki McKibbin

Katherine Nicole "Nikki" McKibbin (born September 28, 1978) is an American rock music singer-songwriter who finished third in the debut season of the reality television series American Idol.

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Paliperidone

Paliperidone, sold under the trade name Invega among others, is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications.

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Paramedic

A paramedic is a healthcare professional who responds to medical emergencies outside of a hospital.

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Paramedics in the United States

In the United States, the paramedic is a paraprofessional whose primary focus is to provide advanced emergency medical care for critical and emergency patients who access Emergency Medical Services (EMS).

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Pfizer

Pfizer Inc. is an American pharmaceutical conglomerate headquartered in New York City, with its research headquarters in Groton, Connecticut.

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Pharmaceutical fraud

Pharmaceutical fraud involves activities that result in false claims to insurers or programs such as Medicare in the United States or equivalent state programs for financial gain to a pharmaceutical company.

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Pharmaceutical industry

The pharmaceutical industry (or medicine industry) is the commercial industry that discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as different types of medicine and medications.

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Pharmaceutical marketing

Pharmaceutical marketing, sometimes called medico-marketing or pharma marketing in some countries, is the business of advertising or otherwise promoting the sale of pharmaceutical drugs.

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Piperazine

Piperazine is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring.

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Porphyria

Porphyria is a group of diseases in which substances called porphyrins build up, negatively affecting the skin or nervous system.

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Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

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Psychiatric medication

A psychiatric medication is a licensed psychoactive drug taken to exert an effect on the chemical makeup of the brain and nervous system.

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Psychomotor agitation

Psychomotor agitation is a set of signs and symptoms that stem from mental tension and anxiety.

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QT interval

In cardiology, the QT interval is a measure of the time between the start of the Q wave and the end of the T wave in the heart's electrical cycle.

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Quetiapine

Quetiapine, marketed as Seroquel among other names, is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.

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Raphael M. Bonelli

Raphael M. Bonelli (born September 10, 1968 in Schärding in Austria) is an Austrian professor of psychiatry, neurology and psychotherapy at the Sigmund Freud University Vienna.

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Schizoaffective disorder

Schizoaffective disorder (SZA, SZD or SAD) is a mental disorder characterized by abnormal thought processes and deregulated emotions.

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Scott Weiland

Scott Richard Weiland (né Kline, October 27, 1967 – December 3, 2015) was an American musician, singer and songwriter.

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Serotonin receptor agonist

A serotonin receptor agonist is an agonist of one or more serotonin receptors.

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Sertindole

Sertindole (brand names: Serdolect and Serlect) is an antipsychotic medication.

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Somnolence

Somnolence (alternatively "sleepiness" or "drowsiness") is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia).

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Sri Siddhartha Medical College

Sri Siddhartha Medical College (SSMC) was started in the year 1988 by Sri Siddhartha Educational Society (SSES).

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Stefan P. Kruszewski

Stefan Philip Kruszewski is an American clinical and forensic psychiatrist, active as a whistleblower in medically related cases.

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Suicide of Megan Meier

Megan Taylor Meier (November 6, 1992 – October 17, 2006) was an American teenager who died by suicide by hanging herself three weeks before her 14th birthday.

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Texas Medication Algorithm Project

The Texas Medication Algorithm Project (TMAP) is a controversial decision-tree medical algorithm, the design of which was based on the expert opinions of mental health specialists.

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Tourette syndrome

Tourette syndrome (TS or simply Tourette's) is a common neuropsychiatric disorder with onset in childhood, characterized by multiple motor tics and at least one vocal (phonic) tic.

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Treatment of bipolar disorder

The emphasis of the treatment of bipolar disorder is on effective management of the long-term course of the illness, which can involve treatment of emergent symptoms.

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Treatment of Tourette syndrome

Tourette syndrome (also Tourette's syndrome or TS) is an inherited neuropsychiatric disorder with onset in childhood, characterized by the presence of motor and phonic tics.

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5-HT receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems.

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5-HT1A receptor

The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptor (5-HT receptor) that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

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5-HT1B receptor

5-hydroxytryptamine receptor 1B also known as the 5-HT1B receptor is a protein that in humans is encoded by the HTR1B gene.

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5-HT1D receptor

5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it.

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5-HT2C receptor

The 5-HT2C receptor is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

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5-HT7 receptor

The 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) The 5-HT7 receptor is coupled to Gs (stimulates the production of the intracellular signaling molecule cAMP) and is expressed in a variety of human tissues, particularly in the brain, the gastrointestinal tract, and in various blood vessels.

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Redirects here:

ATC code N05AE04, ATCvet code QN05AE04, C21H21ClN4OS, Geodom, Geodon, Zaprasidone, Zeldox, Ziprasadone, Ziprasidone Hydrochloride, Ziprasidone hydrochloride, Ziprasidone mesylate.

References

[1] https://en.wikipedia.org/wiki/Ziprasidone

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