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Gamma-Amino-beta-hydroxybutyric acid

Index Gamma-Amino-beta-hydroxybutyric acid

γ-Amino-β-hydroxybutyric acid (GABOB), also known as β-hydroxy-γ-aminobutyric acid (β-hydroxy-GABA), and sold under the brand name Gamibetal among others, is an anticonvulsant which is used for the treatment of epilepsy in Europe, Japan, and Mexico. [1]

26 relations: Adjuvant, Agonist, Anticonvulsant, Baclofen, Blood–brain barrier, Central nervous system, Endogeny (biology), Epilepsy, Europe, GABA analogue, GABA receptor agonist, GABAA receptor, GABAB receptor, Japan, Metabolite, Mexico, Neurotransmitter, Partial agonist, Phenibut, Potency (pharmacology), Pregabalin, Racemic mixture, Stereoisomerism, Stereoselectivity, Structural analog, Trademark distinctiveness.

Adjuvant

An adjuvant is a pharmacological or immunological agent that modifies the effect of other agents.

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Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Anticonvulsant

Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.

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Baclofen

Baclofen, sold under the brand name Lioresal among others, is a medication used to treat spasticity.

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Blood–brain barrier

The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Endogeny (biology)

Endogenous substances and processes are those that originate from within an organism, tissue, or cell.

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Epilepsy

Epilepsy is a group of neurological disorders characterized by epileptic seizures.

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Europe

Europe is a continent located entirely in the Northern Hemisphere and mostly in the Eastern Hemisphere.

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GABA analogue

A GABA analogue is a compound which is an analogue or derivative of the neurotransmitter gamma-Aminobutyric acid (GABA) (the IUPAC of which is 4-aminobutanoic acid).

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GABA receptor agonist

A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects.

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GABAA receptor

The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.

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GABAB receptor

GABAB receptors (GABABR) are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA) that are linked via G-proteins to potassium channels.

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Japan

Japan (日本; Nippon or Nihon; formally 日本国 or Nihon-koku, lit. "State of Japan") is a sovereign island country in East Asia.

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Metabolite

A metabolite is the intermediate end product of metabolism.

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Mexico

Mexico (México; Mēxihco), officially called the United Mexican States (Estados Unidos Mexicanos) is a federal republic in the southern portion of North America.

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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission.

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Partial agonist

In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.

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Phenibut

Phenibut, sold under the brand names Anvifen, Fenibut, and Noofen among others, is a central nervous system depressant with anxiolytic and sedative effects which is used in the treatment of anxiety, insomnia, and for a variety of other indications.

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Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

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Pregabalin

Pregabalin, marketed under the brand name Lyrica among others, is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder.

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Racemic mixture

In chemistry, a racemic mixture, or racemate, is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule.

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Stereoisomerism

In stereochemistry, stereoisomers are isomeric molecules that have the same molecular formula and sequence of bonded atoms (constitution), but differ in the three-dimensional orientations of their atoms in space.

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Stereoselectivity

In chemistry, stereoselectivity is the property of a chemical reaction in which a single reactant forms an unequal mixture of stereoisomers during the non-stereospecific creation of a new stereocenter or during the non-stereospecific transformation of a pre-existing one.

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Structural analog

A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.

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Trademark distinctiveness

Trademark distinctiveness is an important concept in the law governing trademarks and service marks.

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Redirects here:

Aminoxan, Bogil, Bussamina, Buxamina, Buxamine, Diastal, GABOB, Gabimex, Gabomade, Gaboril, Gamalate, Gamibetal, Gamma-amino-beta-hydroxybutyric acid, Kolpo, Β-Hydroxy-GABA, Β-Hydroxy-γ-aminobutyrate, Β-Hydroxy-γ-aminobutyric acid, Β-hydroxy-GABA, Β-hydroxy-γ-aminobutyrate, Β-hydroxy-γ-aminobutyric acid, Γ-Amino-β-hydroxybutyrate, Γ-Amino-β-hydroxybutyric acid, Γ-amino-β-hydroxybutyrate, Γ-amino-β-hydroxybutyric acid.

References

[1] https://en.wikipedia.org/wiki/Gamma-Amino-beta-hydroxybutyric_acid

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