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12 relations: Acute myeloid leukemia, G protein–coupled receptor, Gene, GNA12, GNA13, Insulin-like growth factor 1 receptor, PLXNB1, Protein, Protein–protein interaction, Rho family of GTPases, RHOA, TEC (gene).
Acute myeloid leukemia
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells.
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G protein–coupled receptor
G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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GNA12
Guanine nucleotide-binding protein subunit alpha-12 is a protein that in humans is encoded by the GNA12 gene.
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GNA13
Guanine nucleotide-binding protein subunit alpha-13 is a protein that in humans is encoded by the GNA13 gene.
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Insulin-like growth factor 1 receptor
The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells.
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PLXNB1
Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1 gene.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Rho family of GTPases
The Rho family of GTPases is a family of small (~21 kDa) signaling G proteins, and is a subfamily of the Ras superfamily.
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RHOA
Ras homolog gene family, member A (RhoA) is a small GTPase protein in the Rho family.
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TEC (gene)
Tyrosine-protein kinase Tec is an enzyme that in humans is encoded by the TEC gene.
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