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Auxotrophy

Index Auxotrophy

Auxotrophy (αὐξάνω "to increase"; τροφή "nourishment") is the inability of an organism to synthesize a particular organic compound required for its growth (as defined by IUPAC). [1]

30 relations: Ames test, Amino acid, Autotroph, Bradytroph, Edward Tatum, Escherichia coli, Essential amino acid, Essential fatty acid, Esther Lederberg, Eukaryote, Genetics, George Beadle, Histidine, International Union of Pure and Applied Chemistry, Methionine, Molecular genetics, Mutation, Nobel Prize, Nutrient, One gene–one enzyme hypothesis, Organic compound, Orotidine 5'-phosphate decarboxylase, Protein, Replica plating, Salmonella enterica subsp. enterica, Strain (biology), Uracil, Vitamin, Wild type, Yeast.

Ames test

The Ames test is a widely employed method that uses bacteria to test whether a given chemical can cause mutations in the DNA of the test organism.

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Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

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Autotroph

An autotroph ("self-feeding", from the Greek autos "self" and trophe "nourishing") or producer, is an organism that produces complex organic compounds (such as carbohydrates, fats, and proteins) from simple substances present in its surroundings, generally using energy from light (photosynthesis) or inorganic chemical reactions (chemosynthesis).

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Bradytroph

A bradytroph is a strain of an organism that exhibits slow growth in the absence of an external source of a particular metabolite.

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Edward Tatum

Edward Lawrie Tatum (December 14, 1909 – November 5, 1975) was an American geneticist.

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Escherichia coli

Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).

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Essential amino acid

An essential amino acid, or indispensable amino acid, is an amino acid that cannot be synthesized ''de novo'' (from scratch) by the organism, and thus must be supplied in its diet.

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Essential fatty acid

Essential fatty acids, or EFAs, are fatty acids that humans and other animals must ingest because the body requires them for good health but cannot synthesize them.

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Esther Lederberg

Esther Miriam Zimmer Lederberg (December 18, 1922 – November 11, 2006) was an American microbiologist and a pioneer of bacterial genetics.

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Eukaryote

Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).

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Genetics

Genetics is the study of genes, genetic variation, and heredity in living organisms.

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George Beadle

George Wells Beadle (October 22, 1903 – June 9, 1989) was an American scientist in the field of genetics, and Nobel Prize in Physiology or Medicine Nobel laureate who with Edward Tatum discovered the role of genes in regulating biochemical events within cells in 1958.

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Histidine

Histidine (symbol His or H) is an α-amino acid that is used in the biosynthesis of proteins.

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International Union of Pure and Applied Chemistry

The International Union of Pure and Applied Chemistry (IUPAC) is an international federation of National Adhering Organizations that represents chemists in individual countries.

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Methionine

Methionine (symbol Met or M) is an essential amino acid in humans.

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Molecular genetics

Molecular genetics is the field of biology that studies the structure and function of genes at a molecular level and thus employs methods of both molecular biology and genetics.

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Mutation

In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.

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Nobel Prize

The Nobel Prize (Swedish definite form, singular: Nobelpriset; Nobelprisen) is a set of six annual international awards bestowed in several categories by Swedish and Norwegian institutions in recognition of academic, cultural, or scientific advances.

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Nutrient

A nutrient is a substance used by an organism to survive, grow, and reproduce.

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One gene–one enzyme hypothesis

The one gene–one enzyme hypothesis is the idea that genes act through the production of enzymes, with each gene responsible for producing a single enzyme that in turn affects a single step in a metabolic pathway.

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Organic compound

In chemistry, an organic compound is generally any chemical compound that contains carbon.

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Orotidine 5'-phosphate decarboxylase

Orotidine 5'-phosphate decarboxylase (OMP decarboxylase) or orotidylate decarboxylase is an enzyme involved in pyrimidine biosynthesis.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Replica plating

Replica plating is a microbiological technique in which one or more secondary Petri plates containing different solid (agar-based) selective growth media (lacking nutrients or containing chemical growth inhibitors such as antibiotics) are inoculated with the same colonies of microorganisms from a primary plate (or master dish), reproducing the original spatial pattern of colonies.

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Salmonella enterica subsp. enterica

Salmonella enterica subsp.

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Strain (biology)

In biology, a strain is a low-level taxonomic rank used at the intraspecific level (within a species).

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Uracil

Uracil (U) is one of the four nucleobases in the nucleic acid of RNA that are represented by the letters A, G, C and U. The others are adenine (A), cytosine (C), and guanine (G).

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Vitamin

A vitamin is an organic molecule (or related set of molecules) which is an essential micronutrient - that is, a substance which an organism needs in small quantities for the proper functioning of its metabolism - but cannot synthesize it (either at all, or in sufficient quantities), and therefore it must be obtained through the diet.

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Wild type

Wild type (WT) refers to the phenotype of the typical form of a species as it occurs in nature.

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Yeast

Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom.

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Auxotroph, Auxotrophic, Auxotrophic mutant, Auxotrophs, Prototroph, Prototrophic, Prototrophy.

References

[1] https://en.wikipedia.org/wiki/Auxotrophy

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