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Chiral pool synthesis

Index Chiral pool synthesis

Chiral pool synthesis is a strategy that aims to improve the efficiency of enantioselective synthesis. [1]

17 relations: Amino acid, Chemical compound, Chirality (chemistry), Chiraphos, Enantiomer, Enantioselective synthesis, Epothilone, Functional group, Journal of Organic Chemistry, Journal of the American Chemical Society, Monosaccharide, Organic synthesis, Paclitaxel, Protecting group, Retrosynthetic analysis, Synthesis (journal), 2,3-Butanediol.

Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

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Chemical compound

A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) composed of atoms from more than one element held together by chemical bonds.

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Chirality (chemistry)

Chirality is a geometric property of some molecules and ions.

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Chiraphos

Chiraphos is a chiral diphosphine employed as a ligand in organometallic chemistry.

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Enantiomer

In chemistry, an enantiomer, also known as an optical isomer (and archaically termed antipode or optical antipode), is one of two stereoisomers that are mirror images of each other that are non-superposable (not identical), much as one's left and right hands are the same except for being reversed along one axis (the hands cannot be made to appear identical simply by reorientation).

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Enantioselective synthesis

Enantioselective synthesis, also called asymmetric synthesis, is a form of chemical synthesis.

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Epothilone

The epothilones are a class of potential cancer drugs.

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Functional group

In organic chemistry, functional groups are specific substituents or moieties within molecules that are responsible for the characteristic chemical reactions of those molecules.

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Journal of Organic Chemistry

The Journal of Organic Chemistry, colloquially known as JOC or J Org, is a peer-reviewed scientific journal for original contributions of fundamental research in all branches of theory and practice in organic and bioorganic chemistry.

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Journal of the American Chemical Society

The Journal of the American Chemical Society (also known as JACS) is a weekly peer-reviewed scientific journal that was established in 1879 by the American Chemical Society.

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Monosaccharide

Monosaccharides (from Greek monos: single, sacchar: sugar), also called simple sugars, are the most basic units of carbohydrates.

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Organic synthesis

Organic synthesis is a special branch of chemical synthesis and is concerned with the intentional construction of organic compounds.

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Paclitaxel

Paclitaxel (PTX), sold under the brand name Taxol among others, is a chemotherapy medication used to treat a number of types of cancer.

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Protecting group

A protecting group or protective group is introduced into a molecule by chemical modification of a functional group to obtain chemoselectivity in a subsequent chemical reaction.

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Retrosynthetic analysis

Retrosynthetic analysis is a technique for solving problems in the planning of organic syntheses.

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Synthesis (journal)

Synthesis is a scientific journal published from 1969 to the present day by Thieme.

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2,3-Butanediol

2,3-Butanediol (HOCHMe)2 has three stereoisomers, all of which are colorless, viscous liquids.

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Chiral pool, Enantiomeric scaffolding.

References

[1] https://en.wikipedia.org/wiki/Chiral_pool_synthesis

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