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31 relations: Acetylcholinesterase, Anaphylaxis, Atopic dermatitis, Autotransplantation, Basophil, CCL17, CCL2, CCL5, CD4, Contraindication, Cytotoxic T cell, Danazol, Diphenhydramine, Fabry disease, Hives, Human body temperature, Hypohidrosis, Idiopathic disease, Idiopathic pure sudomotor failure, Immunoglobulin E, Methacholine, Miliaria, Minor test, Muscarinic acetylcholine receptor M3, Neurological disorder, Omalizumab, Perspiration, Physical urticaria, Propranolol, Topical medication, Zileuton.
Acetylcholinesterase
Acetylcholinesterase, encoded by HGNC gene ACHE; EC 3.1.1.7) is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
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Anaphylaxis
Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.
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Atopic dermatitis
Atopic dermatitis (AD), also known as atopic eczema, is a type of inflammation of the skin (dermatitis).
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Autotransplantation
Autotransplantation is the transplantation of organs, tissues, or even particular proteins from one part of the body to another in the same person (auto- meaning "self" in Greek).
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Basophil
Basophils are a type of white blood cells.
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CCL17
Chemokine (C-C motif) ligand 17 (CCL17) (also known as TARC) is a small cytokine belonging to the CC chemokine family is also known as thymus and activation regulated chemokine (TARC).
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CCL2
For the ICAO airport code see Candle Lake Airpark, for the diradical compound see Dichlorocarbene. The chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemoattractant protein 1 (MCP1) and small inducible cytokine A2.
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CCL5
Chemokine (C-C motif) ligand 5 (also CCL5) is a protein which in humans is encoded by the CCL5 gene.
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CD4
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells.
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Contraindication
In medicine, a contraindication is a condition or factor that serves as a reason to withhold a certain medical treatment due to the harm that it would cause the patient.
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Cytotoxic T cell
A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways.
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Danazol
Danazol, sold under the brand name Danocrine among others, is a medication which is used in the treatment of endometriosis, fibrocystic breast disease, hereditary angioedema, and other conditions.
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Diphenhydramine
Diphenhydramine is an antihistamine mainly used to treat allergies.
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Fabry disease
Fabry disease is a rare genetic disease.
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Hives
Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps.
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Human body temperature
Normal human body temperature, also known as normothermia or euthermia, is the typical temperature range found in humans.
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Hypohidrosis
Hypohidrosis is diminished sweating in response to appropriate stimuli.
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Idiopathic disease
An idiopathic disease is any disease with an unknown cause or mechanism of apparently spontaneous origin.
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Idiopathic pure sudomotor failure
Idiopathic pure sudomotor failure (IPSF) is the most common cause of a rare disorder known as acquired idiopathic generalized anhidrosis (AIGA), a clinical syndrome characterized by generalized decrease or absence of sweating without other autonomic and somatic nervous dysfunctions and without persistent organic cutaneous lesions.
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Immunoglobulin E
Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals.
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Methacholine
Methacholine (INN, USAN) (trade name Provocholine) is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system.
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Miliaria
Miliaria, also called "sweat rash", is a skin disease marked by small and itchy rashes.
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Minor test
The Minor test (starch-iodine test) described by Minor in 1928 is a qualitative test used to evaluate sudomotor function (sweating).
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Muscarinic acetylcholine receptor M3
The muscarinic acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded by the human gene CHRM3.
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Neurological disorder
A neurological disorder is any disorder of the nervous system.
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Omalizumab
Omalizumab, sold under the trade name Xolair, is a medication originally designed to reduce sensitivity to allergens.
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Perspiration
Perspiration, also known as sweating, is the production of fluids secreted by the sweat glands in the skin of mammals.
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Physical urticaria
Physical urticaria is a distinct subgroup of the urticaria that are induced by an exogenous physical stimulus rather than occurring spontaneously.
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Propranolol
Propranolol, sold under the brand name Inderal among others, is a medication of the beta blocker type. It is used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors. It is used to prevent migraine headaches, and to prevent further heart problems in those with angina or previous heart attacks. It can be taken by mouth or by injection into a vein. The formulation that is taken by mouth comes in short-acting and long-acting versions. Propranolol appears in the blood after 30 minutes and has a maximum effect between 60 and 90 minutes when taken by mouth. Common side effects include nausea, abdominal pain, and constipation. It should not be used in those with an already slow heart rate and most of those with heart failure. Quickly stopping the medication in those with coronary artery disease may worsen symptoms. It may worsen the symptoms of asthma. Caution is recommended in those with liver or kidney problems. Propranolol may cause harmful effects in the baby if taken during pregnancy. Its use during breastfeeding is probably safe, but the baby should be monitored for side effects. It is a non-selective beta blocker which works by blocking β-adrenergic receptors. Propranolol was discovered in 1964. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Propranolol is available as a generic medication. The wholesale cost in the developing world is between 0.24 and 2.16 per month as of 2014. In the United States it costs about $15 per month at a typical dose.
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Topical medication
A topical medication is a medication that is applied to a particular place on or in the body.
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Zileuton
Zileuton (trade name ZYFLO) is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation, used for the maintenance treatment of asthma.
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References
[1] https://en.wikipedia.org/wiki/Cholinergic_urticaria
