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11 relations: Androgen receptor, Chemoradiotherapy, LNCaP, Metastasis, Osteolysis, PC3, Prostate cancer, Prostate-specific antigen, Retrovirus, Transfection, Xenotransplantation.
Androgen receptor
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
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Chemoradiotherapy
Chemoradiotherapy (CRT, CRTx) is the combination of chemotherapy and radiotherapy to treat cancer.
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LNCaP
LNCaP cells are a cell line of human cells commonly used in the field of oncology.
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Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.
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Osteolysis
Osteolysis is an active resorption of bone matrix by osteoclasts and can be interpreted as the reverse of ossification.
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PC3
PC3 (PC-3) is a human prostate cancer cell line used in prostate cancer research and drug development.
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Prostate cancer
Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system.
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Prostate-specific antigen
Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus. PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia.
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Retrovirus
A retrovirus is a single-stranded positive-sense RNA virus with a DNA intermediate and, as an obligate parasite, targets a host cell.
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Transfection
Transfection is the process of deliberately introducing naked or purified nucleic acids into eukaryotic cells.
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Xenotransplantation
Xenotransplantation (xenos- from the Greek meaning "foreign"), is the transplantation of living cells, tissues or organs from one species to another.
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