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Force spectrum microscopy

Index Force spectrum microscopy

Force Spectrum Microscopy (FSM) is an application of active microrheology developed to measure aggregate random forces in the cytoplasm. [1]

23 relations: Actin, Adenosine triphosphate, Bacteria, Brownian motion, Cancer, Cytoplasm, Cytoskeleton, David A. Weitz, Elasticity (physics), Flow tracer, Fourier transform, Hooke's law, List of breast cancer cell lines, Macromolecular crowding, Malignancy, MCF-7, Mean squared displacement, Metastasis, Microrheology, Myosin, Optical tweezers, Polyethylene glycol, Vesicle (biology and chemistry).

Actin

Actin is a family of globular multi-functional proteins that form microfilaments.

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Adenosine triphosphate

Adenosine triphosphate (ATP) is a complex organic chemical that participates in many processes.

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Bacteria

Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

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Brownian motion

Brownian motion or pedesis (from πήδησις "leaping") is the random motion of particles suspended in a fluid (a liquid or a gas) resulting from their collision with the fast-moving molecules in the fluid.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Cytoplasm

In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.

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Cytoskeleton

A cytoskeleton is present in all cells of all domains of life (archaea, bacteria, eukaryotes).

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David A. Weitz

David A. Weitz (born October 3, 1951) is a Canadian/American physicist and Mallinckrodt Professor of Physics & Applied Physics and professor of Systems Biology at Harvard University.

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Elasticity (physics)

In physics, elasticity (from Greek ἐλαστός "ductible") is the ability of a body to resist a distorting influence and to return to its original size and shape when that influence or force is removed.

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Flow tracer

A flow tracer is any fluid property used to track flow.

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Fourier transform

The Fourier transform (FT) decomposes a function of time (a signal) into the frequencies that make it up, in a way similar to how a musical chord can be expressed as the frequencies (or pitches) of its constituent notes.

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Hooke's law

Hooke's law is a principle of physics that states that the force needed to extend or compress a spring by some distance scales linearly with respect to that distance.

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List of breast cancer cell lines

Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease.

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Macromolecular crowding

The phenomenon of macromolecular crowding alters the properties of molecules in a solution when high concentrations of macromolecules such as proteins are present.

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Malignancy

Malignancy is the tendency of a medical condition to become progressively worse.

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MCF-7

MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old Caucasian woman.

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Mean squared displacement

In statistical mechanics, the mean squared displacement (MSD, also mean square displacement, average squared displacement, or mean square fluctuation) is a measure of the deviation of the position of a particle with respect to a reference position over time.

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Metastasis

Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.

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Microrheology

Microrheology is a technique used to measure the rheological properties of a medium, such as microviscosity, via the measurement of the trajectory of a flow tracer (a micrometre-sized particle).

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Myosin

Myosins are a superfamily of motor proteins best known for their roles in muscle contraction and in a wide range of other motility processes in eukaryotes.

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Optical tweezers

Optical tweezers (originally called "single-beam gradient force trap") are scientific instruments that use a highly focused laser beam to provide an attractive or repulsive force (typically on the order of piconewtons), depending on the relative refractive index between particle and surrounding medium, to physically hold and move microscopic objects similar to tweezers.

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Polyethylene glycol

Polyethylene glycol (PEG) is a polyether compound with many applications from industrial manufacturing to medicine.

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Vesicle (biology and chemistry)

In cell biology, a vesicle is a small structure within a cell, or extracellular, consisting of fluid enclosed by a lipid bilayer.

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References

[1] https://en.wikipedia.org/wiki/Force_spectrum_microscopy

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