Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Androidâ„¢ device!
Free
Faster access than browser!
 

HLA-DO

Index HLA-DO

Human leukocyte histocompatibility complex DO (HLA-DO) is an intracellular, dimeric non-classical Major Histocompatibility Complex (MHC) class II protein composed of α- and β-subunits which interact with HLA-DM in order to fine tune immunodominant epitope selection. [1]

28 relations: Antigen, B cell, Catalysis, Chaperone (protein), Competitive inhibition, Critical Reviews in Immunology, Dendritic cell, Epitope, Exogenous bacteria, Fibroblast, HLA-DM, HLA-DOA, HLA-DOB, Homology (biology), Immunodominance, Interferon gamma, Major histocompatibility complex, MHC class II, N-terminus, Oligopeptide, Phagocytosis, Polymorphism (biology), Protein, Protein dimer, Receptor-mediated endocytosis, Thymus, Transfection, X-ray crystallography.

Antigen

In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.

New!!: HLA-DO and Antigen · See more »

B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.

New!!: HLA-DO and B cell · See more »

Catalysis

Catalysis is the increase in the rate of a chemical reaction due to the participation of an additional substance called a catalysthttp://goldbook.iupac.org/C00876.html, which is not consumed in the catalyzed reaction and can continue to act repeatedly.

New!!: HLA-DO and Catalysis · See more »

Chaperone (protein)

In molecular biology, molecular chaperones are proteins that assist the covalent folding or unfolding and the assembly or disassembly of other macromolecular structures.

New!!: HLA-DO and Chaperone (protein) · See more »

Competitive inhibition

Competitive inhibition is a form of enzyme inhibition where binding of an inhibitor prevents binding of the target molecule of the enzyme, also known as the substrate.

New!!: HLA-DO and Competitive inhibition · See more »

Critical Reviews in Immunology

Critical Reviews in Immunology is a bimonthly scientific journal published by Begell House covering the field of immunology.

New!!: HLA-DO and Critical Reviews in Immunology · See more »

Dendritic cell

Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells) of the mammalian immune system.

New!!: HLA-DO and Dendritic cell · See more »

Epitope

An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells.

New!!: HLA-DO and Epitope · See more »

Exogenous bacteria

Exogenous bacteria are microorganisms introduced to closed biological systems from the external world.

New!!: HLA-DO and Exogenous bacteria · See more »

Fibroblast

A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.

New!!: HLA-DO and Fibroblast · See more »

HLA-DM

HLA-DM (human leukocyte antigen DM) is an intracellular protein involved in the mechanism of antigen presentation on antigen presenting cells (APCs) of the immune system.

New!!: HLA-DO and HLA-DM · See more »

HLA-DOA

HLA class II histocompatibility antigen, DO alpha chain is a protein that in humans is encoded by the HLA-DOA gene.

New!!: HLA-DO and HLA-DOA · See more »

HLA-DOB

HLA class II histocompatibility antigen, DO beta chain is a protein that in humans is encoded by the HLA-DOB gene.

New!!: HLA-DO and HLA-DOB · See more »

Homology (biology)

In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.

New!!: HLA-DO and Homology (biology) · See more »

Immunodominance

Immunodominance is the immunological phenomenon in which immune responses are mounted against only a few of the antigenic peptides out of the many produced.

New!!: HLA-DO and Immunodominance · See more »

Interferon gamma

Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons.

New!!: HLA-DO and Interferon gamma · See more »

Major histocompatibility complex

The major histocompatibility complex (MHC) is a set of cell surface proteins essential for the acquired immune system to recognize foreign molecules in vertebrates, which in turn determines histocompatibility.

New!!: HLA-DO and Major histocompatibility complex · See more »

MHC class II

MHC class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells.

New!!: HLA-DO and MHC class II · See more »

N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.

New!!: HLA-DO and N-terminus · See more »

Oligopeptide

An oligopeptide, often just called peptide (oligo-, "a few"), consists of two to twenty amino acids and can include dipeptides, tripeptides, tetrapeptides, and pentapeptides.

New!!: HLA-DO and Oligopeptide · See more »

Phagocytosis

In cell biology, phagocytosis is the process by which a cell—often a phagocyte or a protist—engulfs a solid particle to form an internal compartment known as a phagosome.

New!!: HLA-DO and Phagocytosis · See more »

Polymorphism (biology)

Polymorphism in biology and zoology is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.

New!!: HLA-DO and Polymorphism (biology) · See more »

Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

New!!: HLA-DO and Protein · See more »

Protein dimer

In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.

New!!: HLA-DO and Protein dimer · See more »

Receptor-mediated endocytosis

Receptor-mediated endocytosis (RME), also called clathrin-mediated endocytosis, is a process by which cells absorb metabolites, hormones, other proteins – and in some cases viruses – by the inward budding of plasma membrane vesicles containing proteins with receptor sites specific to the molecules being absorbed (endocytosis).

New!!: HLA-DO and Receptor-mediated endocytosis · See more »

Thymus

The thymus is a specialized primary lymphoid organ of the immune system.

New!!: HLA-DO and Thymus · See more »

Transfection

Transfection is the process of deliberately introducing naked or purified nucleic acids into eukaryotic cells.

New!!: HLA-DO and Transfection · See more »

X-ray crystallography

X-ray crystallography is a technique used for determining the atomic and molecular structure of a crystal, in which the crystalline atoms cause a beam of incident X-rays to diffract into many specific directions.

New!!: HLA-DO and X-ray crystallography · See more »

References

[1] https://en.wikipedia.org/wiki/HLA-DO

OutgoingIncoming
Hey! We are on Facebook now! »