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HMB-45

Index HMB-45

HMB-45 is a monoclonal antibody that reacts against an antigen present in melanocytic tumors such as melanomas, and stands for Human Melanoma Black. [1]

13 relations: Abcam, Anatomical pathology, Angiomyolipoma, List of histologic stains that aid in diagnosis of cutaneous conditions, Melanocyte, Melanoma, Monoclonal antibody, Neoplasm, Nevus, PMEL (gene), Sarcoma, Schwannoma, Tuberous sclerosis.

Abcam

Abcam is a life-science e-commerce company which facilitates public customer feedback on products using reviews and ratings submitted by customers.

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Anatomical pathology

Anatomical pathology (Commonwealth) or Anatomic pathology (U.S.) is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination of organs and tissues.

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Angiomyolipoma

Angiomyolipomas are the most common benign tumour of the kidney.

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List of histologic stains that aid in diagnosis of cutaneous conditions

A number of histologic stains are used in the field of dermatology that aid in the diagnosis of conditions of or affecting the human integumentary system.

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Melanocyte

Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), the inner ear, vaginal epithelium, meninges, bones, and heart.

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Melanoma

Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes.

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Monoclonal antibody

Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell.

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Neoplasm

Neoplasia is a type of abnormal and excessive growth of tissue.

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Nevus

Nevus (or nevi if multiple) is a nonspecific medical term for a visible, circumscribed, chronic lesion of the skin or mucosa.

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PMEL (gene)

Melanocyte protein PMEL also known as premelanosome protein (PMEL) or silver locus protein homolog (SILV) is a protein that in humans is encoded by the PMEL gene.

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Sarcoma

A sarcoma is a cancer that arises from transformed cells of mesenchymal origin.

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Schwannoma

A schwannoma is a usually benign nerve sheath tumor composed of Schwann cells, which normally produce the insulating myelin sheath covering peripheral nerves.

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Tuberous sclerosis

Tuberous sclerosis, or tuberous sclerosis complex (TSC), or epiloia (acronym of "epilepsy, low intelligence, adenoma sebaceum"), is a rare multisystem genetic disease that causes benign tumors to grow in the brain and on other vital organs such as the kidneys, heart, liver, eyes, lungs, and skin.

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Redirects here:

HMB45, Human Melanoma Black.

References

[1] https://en.wikipedia.org/wiki/HMB-45

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