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35 relations: Cardiotrophin 1, Ciliary neurotrophic factor, Cytokine, ELP2, Glycoprotein 130, GRB2, IL-2 receptor, IL2RB, Interferon, Interleukin 10, Interleukin 10 receptor, alpha subunit, Interleukin 11, Interleukin 13, Interleukin 15, Interleukin 4, Interleukin 6, Interleukin 7, Interleukin 9, IRS1, Leptin, Leukemia inhibitory factor, Metastasis, Neurotrophin, Oncostatin M, Protein–protein interaction, PTPN11, Receptor for activated C kinase 1, STAM2, STAT3, STAT5A, STAT5B, Tumor necrosis factor receptor 1, Type I cytokine receptor, Type II cytokine receptor, Tyrosine kinase.
Cardiotrophin 1
Cardiotrophin-1 (CT-1) is a cytokine.
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Ciliary neurotrophic factor
Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene.
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Cytokine
Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.
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ELP2
Elongator complex protein 2 is a protein that in humans is encoded by the ELP2 gene.
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Glycoprotein 130
Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta or CD130) is a transmembrane protein which is the founding member of the class of all cytokine receptors.
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GRB2
Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein involved in signal transduction/cell communication.
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IL-2 receptor
The interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2.
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IL2RB
Interleukin-2 receptor subunit beta is a protein that in humans is encoded by the IL2RB gene.
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Interferon
Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to the presence of several pathogens, such as viruses, bacteria, parasites, and also tumor cells.
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Interleukin 10
Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine.
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Interleukin 10 receptor, alpha subunit
Interleukin 10 receptor, alpha subunit is a subunit for the interleukin-10 receptor.
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Interleukin 11
Interleukin 11 (IL-11) is a protein that in humans is encoded by the IL11 gene.
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Interleukin 13
Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene.
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Interleukin 15
Interleukin-15 (IL-15) is a cytokine with structural similarity to Interleukin-2 (IL-2).
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Interleukin 4
The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells.
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Interleukin 6
Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine.
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Interleukin 7
Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene.
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Interleukin 9
Interleukin 9, also known as IL-9, is a pleiotropic cytokine (cell signalling molecule) belonging to the group of interleukins.
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IRS1
Insulin receptor substrate 1 (IRS-1) is a signaling adapter protein that in humans is encoded by the IRS-1 gene.
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Leptin
Leptin (from Greek λεπτός leptos, "thin"), "the hormone of energy expenditure", is a hormone predominantly made by adipose cells that helps to regulate energy balance by inhibiting hunger.
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Leukemia inhibitory factor
Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation.
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Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.
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Neurotrophin
Neurotrophins are a family of proteins that induce the survival, development, and function of neurons.
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Oncostatin M
Oncostatin M, also known as OSM, is a protein that in humans is encoded by the OSM gene.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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PTPN11
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) also known as protein-tyrosine phosphatase 1D (PTP-1D), SHP-2, or protein-tyrosine phosphatase 2C (PTP-2C) is an enzyme that in humans is encoded by the PTPN11 gene.
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Receptor for activated C kinase 1
Receptor for activated C kinase 1 (RACK1), also known as guanine nucleotide-binding protein subunit beta-2-like 1 (GNB2L1), is a 35 kDa protein that in humans is encoded by the RACK1 gene.
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STAM2
Signal transducing adapter molecule 2 is a protein that in humans is encoded by the STAM2 gene.
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STAT3
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene.
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STAT5A
Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene.
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STAT5B
Signal transducer and activator of transcription 5B is a protein that in humans is encoded by the STAT5B gene.
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Tumor necrosis factor receptor 1
Tumor necrosis factor receptor 1 (TNFR1), also known as tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) and CD120a, is a ubiquitous membrane receptor that binds tumor necrosis factor-alpha (TNFα).
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Type I cytokine receptor
Type I cytokine receptors are transmembrane receptors expressed on the surface of cells that recognize and respond to cytokines with four α-helical strands.
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Type II cytokine receptor
Type II cytokine receptors are transmembrane proteins that are expressed on the surface of certain cells, which bind and respond to a select group of cytokines.
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Tyrosine kinase
A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to a protein in a cell.
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Redirects here:
JAK1, JAK1 (gene), JAK1A, JAK1B, Jak1a, Jak1b.
References
[1] https://en.wikipedia.org/wiki/Janus_kinase_1
