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23 relations: Alpha helix, Antiparallel (biochemistry), AP2B1, Beta sheet, C-terminus, Cyclin B2, Disulfide, Endoglin, Gene, Heat shock protein 90kDa alpha (cytosolic), member A1, Hereditary hemorrhagic telangiectasia, Loeys–Dietz syndrome, Marfan syndrome, N-terminus, Protein folding, Protein kinase domain, Protein–protein interaction, Serine/threonine-specific protein kinase, STRAP, TGF beta receptor, TGF beta receptor 1, Transforming growth factor, beta 3, Tumor suppressor.
Alpha helix
The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.
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Antiparallel (biochemistry)
In biochemistry, two biopolymers are antiparallel if they run parallel to each other but with opposite alignments.
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AP2B1
AP-2 complex subunit beta is a protein that in humans is encoded by the AP2B1 gene.
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Beta sheet
The β-sheet (also β-pleated sheet) is a common motif of regular secondary structure in proteins.
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C-terminus
The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).
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Cyclin B2
G2/mitotic-specific cyclin-B2 is a protein that in humans is encoded by the CCNB2 gene.
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Disulfide
In chemistry, a disulfide refers to a functional group with the structure R−S−S−R′.
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Endoglin
Endoglin (ENG) is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Heat shock protein 90kDa alpha (cytosolic), member A1
Heat shock protein HSP 90-alpha is a protein that in humans is encoded by the HSP90AA1 gene.
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Hereditary hemorrhagic telangiectasia
Hereditary hemorrhagic telangiectasia (HHT), also known as Osler–Weber–Rendu disease and Osler–Weber–Rendu syndrome, is a rare autosomal dominant genetic disorder that leads to abnormal blood vessel formation in the skin, mucous membranes, and often in organs such as the lungs, liver, and brain.
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Loeys–Dietz syndrome
Loeys–Dietz syndrome (LDS) is an autosomal dominant genetic connective tissue disorder.
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Marfan syndrome
Marfan syndrome (MFS) is a genetic disorder of the connective tissue.
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
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Protein folding
Protein folding is the physical process by which a protein chain acquires its native 3-dimensional structure, a conformation that is usually biologically functional, in an expeditious and reproducible manner.
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Protein kinase domain
The protein kinase domain is a structurally conserved protein domain containing the catalytic function of protein kinases.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Serine/threonine-specific protein kinase
A serine/threonine protein kinase is a kinase enzyme that phosphorylates the OH group of serine or threonine (which have similar sidechains).
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STRAP
Serine-threonine kinase receptor-associated protein is an enzyme that in humans is encoded by the STRAP gene.
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TGF beta receptor
Transforming growth factor beta (TGFβ) receptors are single pass serine/threonine kinase receptors.
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TGF beta receptor 1
Transforming growth factor beta receptor I (activin A receptor type II-like kinase, 53kDa) is a membrane-bound receptor protein for the TGF beta superfamily of signaling ligands.
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Transforming growth factor, beta 3
Transforming growth factor beta-3 is a protein that in humans is encoded by the TGFB3 gene.
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Tumor suppressor
A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer.
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Redirects here:
AAT3, Aat3, FAA3, Faa3, HNPCC6, Hnpcc6, MFS2, Mfs2, RIIC, Riic, TAAD2, TGFBR2, TGFBR2 (gene), TGFR-2, TGFbeta-RII, TGFβR2, TGFβRII, Taad2, Tgfbeta-rii, Tgfr-2.
References
[1] https://en.wikipedia.org/wiki/TGF_beta_receptor_2
