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98 relations: Addiction, Administrative Controlled Substances Code Number, Alkaline phosphatase, Amnesia, Analgesic, Anaphylaxis, Anesthesiologist, Apnea, Associated Press, AstraZeneca, Azobenzene, Benzodiazepine, Benzyl alcohol, Biological half-life, Caesarean section, Catecholamine, Conrad Murray, Controlled substance, Corticosteroid, Death of Michael Jackson, Developing country, Diazepam, Diazirine, Dose–response relationship, Drug Enforcement Administration, Drug metabolism, Drug-induced amnesia, Dystonia, Egg lecithin, Electroencephalography, Emulsion, Endocannabinoid system, Epileptic seizure, Food and Drug Administration, Fospropofol, Functional residual capacity, GABA receptor agonist, GABAA receptor, GABAA receptor positive allosteric modulator, Gamma wave, Gamma-Aminobutyric acid, General anaesthesia, Generic drug, Glucuronidation, Glycerol, Health system, Heart arrhythmia, Hyaluronic acid, Hypotension, Hypoventilation, ..., Imperial Chemical Industries, Intensive care unit, Intracranial pressure, Intraocular pressure, Intravenous therapy, Jay Nixon, Ketamine, Kolliphor EL, Lidocaine, Liver, Lorazepam, Magnesium hydroxide, Magnetic resonance imaging, Malignant hyperthermia, Mechanical ventilation, Michael Jackson, Midazolam, Morphine, Myoclonus, Off-label use, Opiate, Opioid, Porphyria, Pregnancy, Priapism, Procedural sedation and analgesia, Prodrug, Propofol infusion syndrome, Radical (chemistry), Respiratory minute volume, Respiratory rate, Scribd, Sodium channel, Sodium hydroxide, Sodium metabisulfite, Sodium thiopental, Soybean oil, Status epilepticus, Synovial fluid, Target controlled infusion, Tidal volume, Tonicity, TRPA1, Vascular resistance, Vasodilation, Veterinary medicine, WebMD, WHO Model List of Essential Medicines. Expand index (48 more) »
Addiction
Addiction is a brain disorder characterized by compulsive engagement in rewarding stimuli despite adverse consequences.
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Administrative Controlled Substances Code Number
Administrative Controlled Substances Code Number (ACSCN) is a number assigned to drugs listed on the schedules created by the Controlled Substances Act (CSA).
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Alkaline phosphatase
Alkaline phosphatase (ALP, ALKP, ALPase, Alk Phos) or basic phosphatase is a homodimeric protein enzyme of 86 kilodaltons.
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Amnesia
Amnesia is a deficit in memory caused by brain damage, disease, or psychological trauma.
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Analgesic
An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.
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Anaphylaxis
Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.
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Anesthesiologist
An anesthesiologist is a physician trained in anesthesia and perioperative medicine.
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Apnea
Apnea or apnoea is suspension of breathing.
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Associated Press
The Associated Press (AP) is a U.S.-based not-for-profit news agency headquartered in New York City.
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AstraZeneca
AstraZeneca plc is an Anglo–Swedish multinational pharmaceutical and biopharmaceutical company.
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Azobenzene
Azobenzene is a chemical compound composed of two phenyl rings linked by a N.
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Benzodiazepine
Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.
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Benzyl alcohol
Benzyl alcohol is an aromatic alcohol with the formula C6H5CH2OH.
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Biological half-life
The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.
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Caesarean section
Caesarean section, also known as C-section or caesarean delivery, is the use of surgery to deliver one or more babies.
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Catecholamine
A catecholamine (CA) is a monoamine, an organic compound that has a catechol (benzene with two hydroxyl side groups at carbons 1 and 2) and a side-chain amine.
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Conrad Murray
Conrad Robert Murray (born February 19, 1953) is an American cardiologist and was the personal physician of Michael Jackson at the time of the singer's death in 2009, in which he was implicated.
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Controlled substance
A controlled substance is generally a drug or chemical whose manufacture, possession, or use is regulated by a government, such as illicitly used drugs or prescription medications that are designated a Controlled Drug in the United Kingdom.
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Corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.
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Death of Michael Jackson
On June 25, 2009, Michael Jackson died of acute propofol and benzodiazepine intoxication at his home on North Carolwood Drive in the Holmby Hills neighborhood of Los Angeles.
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Developing country
A developing country (or a low and middle income country (LMIC), less developed country, less economically developed country (LEDC), underdeveloped country) is a country with a less developed industrial base and a low Human Development Index (HDI) relative to other countries.
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Diazepam
Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that typically produces a calming effect.
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Diazirine
Diazirines are a class of organic molecules consisting of a carbon bound to two nitrogen atoms, which are double-bonded to each other, forming a cyclopropene-like ring, 3H-diazirene.
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Dose–response relationship
The dose–response relationship, or exposure–response relationship, describes the change in effect on an organism caused by differing levels of exposure (or doses) to a stressor (usually a chemical) after a certain exposure time, or to a food.
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Drug Enforcement Administration
The Drug Enforcement Administration (DEA) is a United States federal law enforcement agency under the United States Department of Justice, tasked with combating drug smuggling and use within the United States.
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Drug metabolism
Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems.
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Drug-induced amnesia
Drug-induced amnesia is amnesia caused by drugs.
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Dystonia
Dystonia is a neurological movement disorder syndrome in which sustained or repetitive muscle contractions result in twisting and repetitive movements or abnormal fixed postures.
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Egg lecithin
Egg lecithin is a type of lecithin, a group of compounds primarily containing phospholipids, that is derived from eggs.
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Electroencephalography
Electroencephalography (EEG) is an electrophysiological monitoring method to record electrical activity of the brain.
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Emulsion
An emulsion is a mixture of two or more liquids that are normally immiscible (unmixable or unblendable).
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Endocannabinoid system
The endocannabinoid system (ECS) is a biological system composed of endocannabinoids, which are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the mammalian central nervous system (including the brain) and peripheral nervous system.
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Epileptic seizure
An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.
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Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
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Fospropofol
Fospropofol (INN), often used as the disodium salt (trade name Lusedra) is an intravenous sedative-hypnotic agent. It is currently approved for use in sedation of adult patients undergoing diagnostic or therapeutic procedures such as endoscopy.
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Functional residual capacity
Functional Residual Capacity (FRC) is the volume of air present in the lungs at the end of passive expiration.
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GABA receptor agonist
A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects.
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GABAA receptor
The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.
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GABAA receptor positive allosteric modulator
In pharmacology, GABAA receptor positive allosteric modulators are positive allosteric modulator (PAM) molecules that increase the activity of the GABAA receptor protein in the vertebrate central nervous system.
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Gamma wave
A gamma wave is a pattern of neural oscillation in humans with a frequency between 25 and 100 Hz, though 40 Hz is typical.
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Gamma-Aminobutyric acid
gamma-Aminobutyric acid, or γ-aminobutyric acid, or GABA, is the chief inhibitory neurotransmitter in the mammalian central nervous system.
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General anaesthesia
General anaesthesia or general anesthesia (see spelling differences) is a medically induced coma with loss of protective reflexes, resulting from the administration of one or more general anaesthetic agents.
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Generic drug
A generic drug is a pharmaceutical drug that is equivalent to a brand-name product in dosage, strength, route of administration, quality, performance, and intended use, but does not carry the brand name.
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Glucuronidation
Glucuronidation is often involved in drug metabolism of substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids.
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Glycerol
Glycerol (also called glycerine or glycerin; see spelling differences) is a simple polyol compound.
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Health system
A health system, also sometimes referred to as health care system or as healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.
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Heart arrhythmia
Heart arrhythmia (also known as arrhythmia, dysrhythmia, or irregular heartbeat) is a group of conditions in which the heartbeat is irregular, too fast, or too slow.
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Hyaluronic acid
Hyaluronic acid (HA; conjugate base hyaluronate), also called hyaluronan, is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues.
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Hypotension
Hypotension is low blood pressure, especially in the arteries of the systemic circulation.
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Hypoventilation
Hypoventilation (also known as respiratory depression) occurs when ventilation is inadequate (hypo meaning "below") to perform needed gas exchange.
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Imperial Chemical Industries
Imperial Chemical Industries (ICI) was a British chemical company and was, for much of its history, the largest manufacturer in Britain.
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Intensive care unit
Intensive care unit An intensive care unit (ICU), also known as an intensive therapy unit or intensive treatment unit (ITU) or critical care unit (CCU), is a special department of a hospital or health care facility that provides intensive treatment medicine.
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Intracranial pressure
Intracranial pressure (ICP) is the pressure inside the skull and thus in the brain tissue and cerebrospinal fluid (CSF).
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Intraocular pressure
Intraocular pressure (IOP) is the fluid pressure inside the eye.
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Intravenous therapy
Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).
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Jay Nixon
Jeremiah Wilson "Jay" Nixon (born February 13, 1956) is an American politician and lawyer who served as the 55th Governor of Missouri from 2009 to 2017 as a member of the Democratic Party.
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Ketamine
Ketamine, sold under the brand name Ketalar among others, is a medication mainly used for starting and maintaining anesthesia.
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Kolliphor EL
Kolliphor EL, formerly known as Cremophor EL, is the registered trademark of BASF Corp.
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Lidocaine
Lidocaine, also known as xylocaine and lignocaine, is a medication used to numb tissue in a specific area.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Lorazepam
Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication.
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Magnesium hydroxide
Magnesium hydroxide is the inorganic compound with the chemical formula Mg(OH)2.
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Magnetic resonance imaging
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body in both health and disease.
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Malignant hyperthermia
Malignant hyperthermia (MH) is a type of severe reaction that occurs to particular medications used during general anesthesia, among those who are susceptible.
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Mechanical ventilation
Mechanical ventilation is the medical term for artificial ventilation where mechanical means is used to assist or replace spontaneous breathing. This may involve a machine called a ventilator or the breathing may be assisted by an anesthesiologist, certified registered nurse anesthetist, physician, physician assistant, respiratory therapist, paramedic, EMT, or other suitable person compressing a bag or set of bellows. Mechanical ventilation is termed "invasive" if it involves any instrument penetrating the trachea through the mouth, such as an endotracheal tube or the skin, such as a tracheostomy tube. There are two main types: positive pressure ventilation, where air (or another gas mix) is pushed into the trachea, and negative pressure ventilation, where air is, in essence, sucked into the lungs. There are many modes of mechanical ventilation, and their nomenclature has been revised over the decades as the technology has continually developed.
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Michael Jackson
Michael Joseph Jackson (August 29, 1958 – June 25, 2009) was an American singer, songwriter, and dancer.
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Midazolam
Midazolam, marketed under the trade name Versed, among others, is a medication used for anesthesia, procedural sedation, trouble sleeping, and severe agitation.
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Morphine
Morphine is a pain medication of the opiate variety which is found naturally in a number of plants and animals.
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Myoclonus
Myoclonus is a brief, involuntary twitching of a muscle or a group of muscles.
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Off-label use
Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration.
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Opiate
Opiate is a term classically used in pharmacology to mean a drug derived from opium.
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Opioid
Opioids are substances that act on opioid receptors to produce morphine-like effects.
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Porphyria
Porphyria is a group of diseases in which substances called porphyrins build up, negatively affecting the skin or nervous system.
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Pregnancy
Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.
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Priapism
Priapism is a condition in which a penis remains erect for hours in the absence of stimulation or after stimulation has ended.
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Procedural sedation and analgesia
Procedural sedation and analgesia, previously referred to as conscious sedation, is defined as "a technique of administering sedatives or dissociative agents with or without analgesics to induce a state that allows the patient to tolerate unpleasant procedures while maintaining cardiorespiratory function.".
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Prodrug
A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.
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Propofol infusion syndrome
Propofol infusion syndrome (PRIS) is a rare syndrome which affects patients undergoing long-term treatment with high doses of the anaesthetic and sedative drug propofol.
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Radical (chemistry)
In chemistry, a radical (more precisely, a free radical) is an atom, molecule, or ion that has an unpaired valence electron.
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Respiratory minute volume
Respiratory minute volume (or minute ventilation or minute volume) is the volume of gas inhaled (inhaled minute volume) or exhaled (exhaled minute volume) from a person's lungs per minute.
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Respiratory rate
The respiratory rate is the rate at which breathing occurs.
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Scribd
Scribd is a digital library, e-book and audiobook subscription service that includes one million titles.
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Sodium channel
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
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Sodium hydroxide
Sodium hydroxide, also known as lye, is an inorganic compound with the formula NaOH. It is a white solid ionic compound consisting of sodium cations and hydroxide anions. Sodium hydroxide is a highly caustic base and alkali that decomposes proteins at ordinary ambient temperatures and may cause severe chemical burns. It is highly soluble in water, and readily absorbs moisture and carbon dioxide from the air. It forms a series of hydrates NaOH·n. The monohydrate NaOH· crystallizes from water solutions between 12.3 and 61.8 °C. The commercially available "sodium hydroxide" is often this monohydrate, and published data may refer to it instead of the anhydrous compound. As one of the simplest hydroxides, it is frequently utilized alongside neutral water and acidic hydrochloric acid to demonstrate the pH scale to chemistry students. Sodium hydroxide is used in many industries: in the manufacture of pulp and paper, textiles, drinking water, soaps and detergents, and as a drain cleaner. Worldwide production in 2004 was approximately 60 million tonnes, while demand was 51 million tonnes.
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Sodium metabisulfite
Sodium metabisulfite or sodium pyrosulfite (IUPAC spelling; Br. E. sodium metabisulphite or sodium pyrosulphite) is an inorganic compound of chemical formula Na2S2O5.
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Sodium thiopental
Sodium thiopental, also known as Sodium Pentothal (a trademark of Abbott Laboratories, not to be confused with pentobarbital), thiopental, thiopentone, or Trapanal (also a trademark), is a rapid-onset short-acting barbiturate general anesthetic that is an analogue of thiobarbital.
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Soybean oil
Soybean oil is a vegetable oil extracted from the seeds of the soybean (Glycine max).
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Status epilepticus
Status epilepticus (SE) is a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to normal between them.
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Synovial fluid
Synovial fluid, also called synovia,help 1 is a viscous, non-Newtonian fluid found in the cavities of synovial joints.
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Target controlled infusion
Target-controlled infusion (TCI) automates the dosing of intravenous drugs during surgery.
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Tidal volume
Tidal volume (symbol VT or TV) is the lung volume representing the normal volume of air displaced between normal inhalation and exhalation when extra effort is not applied.
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Tonicity
Tonicity is a measure of the effective osmotic pressure gradient, as defined by the water potential of two solutions separated by a semipermeable membrane.
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TRPA1
Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1 or TRPA1, is a protein that in humans is encoded by the TRPA1 (and in other species by the Trpa1) gene.
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Vascular resistance
Vascular resistance is the resistance that must be overcome to push blood through the circulatory system and create flow.
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Vasodilation
Vasodilation is the widening of blood vessels.
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Veterinary medicine
Veterinary medicine is the branch of medicine that deals with the prevention, diagnosis and treatment of disease, disorder and injury in non-human animals.
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WebMD
WebMD is an American corporation known primarily as an online publisher of news and information pertaining to human health and well-being.
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WHO Model List of Essential Medicines
The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
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Redirects here:
2,6-diisopropylphenol, ATC code N01AX10, ATCvet code QN01AX10, Deprivan, Diprivan, Disoprivan, Disoprofol, Milk of amnesia, Propafol, Propofal, Propofol phosphate, Propophol, Rapinovet.
References
[1] https://en.wikipedia.org/wiki/Propofol
