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Spindle apparatus

Index Spindle apparatus

In cell biology, the spindle apparatus (or mitotic spindle) refers to the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter cells. [1]

55 relations: African clawed frog, Anaphase, Aneuploidy, Antiparallel (biochemistry), Aster (cell biology), ATP hydrolysis, Aurora A kinase, Aurora B kinase, Aurora kinase, Cell (biology), Cell biology, Cell division, Cell division orientation, Centromere, Centrosome, Chromosome, CLASP1, CLIP1, Cohesin, Cytoskeleton, Drosophila melanogaster, Dynamic instability, Dynein, Ellipsoid, Eukaryote, Fungus, Gamete, Genetics, Hertwig rule, Histone H1, Karyotype, Katanin, Kinesin, Kinetochore, Meiosis, Microtubule, Microtubule nucleation, Microtubule organizing center, Microtubule-associated protein, Mitosis, Nuclear envelope, PLK1, Polo-like kinase, Prometaphase, Protein, Protein dimer, Ran (protein), RCC1, Sister chromatids, Spindle checkpoint, ..., Spindle poison, Spindle pole body, Stathmin, Tubulin, Yeast. Expand index (5 more) »

African clawed frog

The African clawed frog (Xenopus laevis, also known as the xenopus, African clawed toad, African claw-toed frog or the platanna) is a species of African aquatic frog of the family Pipidae.

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Anaphase

Anaphase (from the Greek ἀνά, "up" and φάσις, "stage"), is the stage of mitosis after the metaphase when replicated chromosomes are split and the daughter chromatids are moved to opposite poles of the cell.

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Aneuploidy

Aneuploidy is the presence of an abnormal number of chromosomes in a cell, for example a human cell having 45 or 47 chromosomes instead of the usual 46.

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Antiparallel (biochemistry)

In biochemistry, two biopolymers are antiparallel if they run parallel to each other but with opposite alignments.

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Aster (cell biology)

An aster is a cellular structure shaped like a star, formed around each centrosome during mitosis in an animal cell.

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ATP hydrolysis

ATP hydrolysis is the catabolic reaction process by which chemical energy that has been stored in the high-energy phosphoanhydride bonds in adenosine triphosphate (ATP) is released by splitting these bonds, for example in muscles, by producing work in the form of mechanical energy.

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Aurora A kinase

Aurora kinase A also known as serine/threonine-protein kinase 6 is an enzyme that in humans is encoded by the AURKA gene.

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Aurora B kinase

Aurora B kinase is a protein that functions in the attachment of the mitotic spindle to the centromere.

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Aurora kinase

Aurora kinases are serine/threonine kinases that are essential for cell proliferation.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Cell biology

Cell biology (also called cytology, from the Greek κυτος, kytos, "vessel") is a branch of biology that studies the structure and function of the cell, the basic unit of life.

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Cell division

Cell division is the process by which a parent cell divides into two or more daughter cells.

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Cell division orientation

Cell division orientation is the direction along which the new daughter cells are formed.

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Centromere

The centromere is the specialized DNA sequence of a chromosome that links a pair of sister chromatids (a dyad).

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Centrosome

In cell biology, the centrosome (Latin centrum 'center' + Greek sōma 'body') is an organelle that serves as the main microtubule organizing center (MTOC) of the animal cell as well as a regulator of cell-cycle progression.

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Chromosome

A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.

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CLASP1

Cytoplasmic linker associated protein 1, also known as CLASP1, is a protein which in humans is encoded by the CLASP1 gene.

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CLIP1

CAP-GLY domain containing linker protein 1, also known as CLIP1, is a protein which in humans is encoded by the CLIP1 gene.

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Cohesin

Cohesin is a protein complex that regulates the separation of sister chromatids during cell division, either mitosis or meiosis.

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Cytoskeleton

A cytoskeleton is present in all cells of all domains of life (archaea, bacteria, eukaryotes).

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Drosophila melanogaster

Drosophila melanogaster is a species of fly (the taxonomic order Diptera) in the family Drosophilidae.

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Dynamic instability

Dynamic instability may refer to any of several scientific phenomena.

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Dynein

Dynein is a family of cytoskeletal motor proteins that move along microtubules in cells.

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Ellipsoid

An ellipsoid is a surface that may be obtained from a sphere by deforming it by means of directional scalings, or more generally, of an affine transformation.

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Eukaryote

Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).

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Fungus

A fungus (plural: fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms.

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Gamete

A gamete (from Ancient Greek γαμετή gamete from gamein "to marry") is a haploid cell that fuses with another haploid cell during fertilization (conception) in organisms that sexually reproduce.

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Genetics

Genetics is the study of genes, genetic variation, and heredity in living organisms.

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Hertwig rule

Hertwig's rule or 'long axis rule' states that a cell divides along its long axis.

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Histone H1

Histone H1 is one of the five main histone protein families which are components of chromatin in eukaryotic cells.

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Karyotype

A karyotype is the number and appearance of chromosomes in the nucleus of a eukaryotic cell.

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Katanin

Katanin is a microtubule-severing AAA protein.

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Kinesin

A kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells.

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Kinetochore

A kinetochore is a disc-shaped protein structure, found at the centromere of a chromatid, to which microtubules attach during cell division.

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Meiosis

Meiosis (from Greek μείωσις, meiosis, which means lessening) is a specialized type of cell division that reduces the chromosome number by half, creating four haploid cells, each genetically distinct from the parent cell that gave rise to them.

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Microtubule

Microtubules are tubular polymers of tubulin that form part of the cytoskeleton that provides the cytoplasm of eukaryotic cells and some bacteria with structure and shape.

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Microtubule nucleation

In cell biology, microtubule nucleation is the event that initiates de novo formation of microtubules (MTs).

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Microtubule organizing center

The microtubule-organizing center (MTOC) is a structure found in eukaryotic cells from which microtubules emerge.

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Microtubule-associated protein

In cell biology, microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton.

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Mitosis

In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.

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Nuclear envelope

The nuclear envelope, also known as the nuclear membrane, is made up of two lipid bilayer membranes which surrounds the nucleus, and in eukaryotic cells it encases the genetic material.

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PLK1

Serine/threonine-protein kinase PLK1, also known as polo-like kinase 1 (PLK-1) or serine/threonine-protein kinase 13 (STPK13), is an enzyme that in humans is encoded by the PLK1 (polo-like kinase 1) gene.

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Polo-like kinase

Polo-like kinases (Plks) are regulatory serine/threonin kinases of the cell cycle involved in mitotic entry, mitotic exit, spindle formation, cytokinesis, and meiosis.

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Prometaphase

Prometaphase is the phase of mitosis following prophase and preceding metaphase, in eukaryotic somatic cells.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein dimer

In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.

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Ran (protein)

Ran (RAs-related Nuclear protein) also known as GTP-binding nuclear protein Ran is a protein that in humans is encoded by the RAN gene.

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RCC1

Regulator of chromosome condensation 1, also known as RCC1, Ran guanine nucleotide exchange factor and RanGEF, is the name for a human gene and protein.

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Sister chromatids

A sister chromatid refers to the identical copies (chromatids) formed by the replication of a chromosome, with both copies joined together by a common centromere.

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Spindle checkpoint

During the process of cell division, the spindle checkpoint prevents separation of the duplicated chromosomes until each chromosome is properly attached to the spindle apparatus.

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Spindle poison

A spindle poison, also known as a spindle toxin, is a poison that disrupts cell division by affecting the protein threads that connect the centromere regions of chromosomes, known as spindles.

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Spindle pole body

The spindle pole body (SPB) is the microtubule organizing center in yeast cells, functionally equivalent to the centrosome.

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Stathmin

Stathmin, also known as metablastin and oncoprotein 18 is a protein that in humans is encoded by the STMN1 gene.

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Tubulin

Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of the member proteins of that superfamily.

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Yeast

Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom.

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Meiotic spindle, Metaphase plate, Mitotic apparatus, Mitotic spindle, Mitotic spindle apparatus, Mitotic spindles, Nuclear spindle, Spindle (cell), Spindle fiber, Spindle fibers, Spindle pole, The Spindle apparatus, The spindle apparatus.

References

[1] https://en.wikipedia.org/wiki/Spindle_apparatus

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