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19 relations: Arthritis Research & Therapy, AU-rich element, Cytokine, Gene, Messenger RNA, MicroRNA, Mir-29 microRNA precursor, Nuclear pore, Nucleoporin 214, Post-transcriptional regulation, Protein, Protein kinase, Protein–protein interaction, Subcellular localization, Tumor necrosis factor alpha, YWHAH, ZFP36L1, 12-O-Tetradecanoylphorbol-13-acetate, 14-3-3 protein.
Arthritis Research & Therapy
Arthritis Research & Therapy, formerly Arthritis Research, is a peer-reviewed open access medical journal covering the field of cellular and molecular mechanisms of arthritis, musculoskeletal conditions, and systemic autoimmune rheumatic diseases.
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AU-rich element
Adenylate-uridylate-rich elements (AU-rich elements; AREs) are found in the 3' untranslated region (UTR) of many messenger RNAs (mRNAs) that code for proto-oncogenes, nuclear transcription factors, and cytokines.
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Cytokine
Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Messenger RNA
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
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MicroRNA
A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression.
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Mir-29 microRNA precursor
The miR-29 microRNA precursor, or pre-miRNA, is a small RNA molecule in the shape of a stem-loop or hairpin.
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Nuclear pore
Nuclear pore complexes are large protein complexes that span the nuclear envelope, which is the double membrane surrounding the eukaryotic cell nucleus.
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Nucleoporin 214
Nucleoporin 214 (Nup2014) is a protein that in humans is encoded by the NUP214 gene.
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Post-transcriptional regulation
Italic textÀ Post-transcriptional regulation is the control of gene expression at the RNA level, therefore between the transcription and the translation of the gene.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein kinase
A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation).
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Subcellular localization
The cells of eukaryotic organisms are elaborately subdivided into functionally-distinct membrane-bound compartments.
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Tumor necrosis factor alpha
Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.
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YWHAH
14-3-3 protein eta is a protein that in humans is encoded by the YWHAH gene.
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ZFP36L1
Butyrate response factor 1 is a protein that in humans is encoded by the ZFP36L1 gene.
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12-O-Tetradecanoylphorbol-13-acetate
12-O-Tetradecanoylphorbol-13-acetate (TPA), also commonly known as tetradecanoylphorbol acetate, tetradecanoyl phorbol acetate, and phorbol 12-myristate 13-acetate (PMA), is a diester of phorbol and a potent tumor promoter often employed in biomedical research to activate the signal transduction enzyme protein kinase C (PKC).
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14-3-3 protein
14-3-3 proteins are a family of conserved regulatory molecules that are expressed in all eukaryotic cells.
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Tristetraprolin, ZFP36 (gene).
