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Alcohol (drug)

Index Alcohol (drug)

Alcohol, also known by its chemical name ethanol, is a psychoactive substance or drug that is the active ingredient in alcoholic beverages such as beer, wine, and distilled spirits (hard liquor). [1]

325 relations: Acetaldehyde, Acetaldehyde dehydrogenase, Acetate, Acetic acid, Acetone, Acetyl-CoA, Acetylcholine, Active ingredient, Addiction, Adenosine reuptake inhibitor, Adverse effect, Afghanistan, Alcohol, Alcohol abuse, Alcohol and cancer, Alcohol dehydrogenase, Alcohol dependence, Alcohol detoxification, Alcohol flush reaction, Alcohol intoxication, Alcohol tolerance, Alcoholic drink, Alcoholic liver disease, Alcoholism, Aldehyde, Aldehyde dehydrogenase, Allergen, Allergy, Allosteric modulator, Allosteric regulation, Amnesia, AMPA receptor, Anesthetic, Antidepressant, Antihistamine, Antipsychotic, Antiseptic, Anxiety, Anxiolytic, Arrest, Assault, Asthma, Bangladesh, Bar, Barbiturate, Barley, Beer, Benzodiazepine, Binding site, Bioavailability, ..., Biological half-life, Biological membrane, Biological target, Biotransformation, BK channel, Blood alcohol content, Blood–brain barrier, Bone, Brain, Breathing, Brewing, Bronchoconstriction, CAMK, Cancer, Cannabis, Carbohydrate, Carbon dioxide, Carboxylic acid, Catalase, Central nervous system, Central nervous system depression, Channel blocker, Channel opener, Chemical compound, Chemical formula, Chemical industry, Chemical synapse, Chloral hydrate, Chloralodol, Chloride, Chloroform, Cholesterol, Cirrhosis, Clostridium difficile (bacteria), Cmax (pharmacology), Cocaethylene, Cocaine, Coenzyme A, Cognition, Cognitive deficit, Coma, Combustibility and flammability, Confusion, Cornea, CREB, CYP2E1, Cytochrome P450, Date rape drug, Delirium tremens, Depressant, Dermatitis, Dexmethylphenidate, Diethyl ether, Disease, Disinfectant, Distillation, Distribution (pharmacology), Disulfiram, Dizziness, Domestic violence, Dopamine, Dopamine receptor D1, Dose–response relationship, Downregulation and upregulation, Drinking establishment, Drug overdose, Drug tolerance, Drug withdrawal, Drunk drivers, Dysautonomia, Egypt, Elimination (pharmacology), Emergency department, Empty calorie, Endogeny (biology), Enzyme, Enzyme inducer, Epileptic seizure, Ethanol, Ethchlorvynol, Ethyl glucuronide, Ethyl group, Ethyl sulfate, Ethylene, Ethylene glycol, Euphoria, Fasting, Fat, Fermentation, Festival, Fever, Flumazenil, Formaldehyde, Formic acid, Fuel, G protein-coupled inwardly-rectifying potassium channel, GABAA receptor, GABRD, Gastrointestinal tract, Gene expression, General anaesthetic, Georgia (country), Glutamic acid, Glycine, Glycine receptor, Glycine reuptake inhibitor, Grape juice, Hallucination, Hangover, Happiness, Heart rate, Hepatotoxicity, High-density lipoprotein, Histamine, Hives, Human, Human body weight, Hydration reaction, Hydroxy group, Hypnotic, Hypoventilation, India, Indian reservation, Inhalation, Inhalational anaesthetic, Injection (medicine), Injury, Insomnia, International Agency for Research on Cancer, Intestinal mucosal barrier, Intimate partner violence, Intravenous therapy, Ion channel, Ionotropic glutamate receptor, Iran, Irritation, Isoflurane, Isopropyl alcohol, Kainate receptor, KEGG, Ketone, Kidney, Kuwait, L-type calcium channel, Libya, Life expectancy, Ligand-gated ion channel, Liquid, Liquor, Liver, MAPK/ERK pathway, Marital breakdown, Mechanism of action, Median lethal dose, Memory, Mesolimbic pathway, Metabolic pathway, Metabolism, Metabolite, Methanol, Methylpentynol, Methylphenidate, Metronidazole, Middle East, Mixture, Molar concentration, Molasses, Molecular mass, Mortality rate, Motor control, Murder, N-Butanol, National Institute on Alcohol Abuse and Alcoholism, Natural product, Nausea, Necessity and sufficiency, Neurotoxicity, Neurotransmitter, Nicotinamide adenine dinucleotide, Nicotinic acetylcholine receptor, Nightclub, NMDA receptor, Nonbenzodiazepine, Northern and southern China, Nucleus accumbens, Odor, Opioid, Oral administration, Organic brain syndrome, Paraldehyde, Party, Passive transport, Peptic ulcer disease, Perspiration, Petrochemical, Pharmacodynamics, Phosphorylation, Physical disability, Plasma protein binding, Pleasure, Pliny the Elder, Potency (pharmacology), Primary alcohol, Properties of water, Protein, Protein kinase A, Protein subunit, Psychoactive drug, Psychomotor agitation, Pulmonary edema, Race (human categorization), Rape, Rate equation, Receptor (biochemistry), Recreational drug use, Rectal administration, Redox, Reinforcement, Respiratory failure, Rhinitis, Ro15-4513, Rome, Saccharomyces cerevisiae, Saudi Arabia, Sedation, Sedative, Sense, Sensory loss, Serotonin, Sexual assault, Small intestine, Social behavior, Solvent, Somalia, Stimulant, Stomach, Structural analog, Stupor, Substance dependence, Sudan, Sugar, Sugarcane, Sugarcane juice, Teratology, Tert-Amyl alcohol, Tetrahydrocannabinol, Toxicity, Traffic collision, Transcaucasia, Transparency and translucency, Tremor, Triglyceride, Unconsciousness, United States, Urine, Vapor, Ventral tegmental area, Vineyard, Violent crime, Volatility (chemistry), Voltage-gated calcium channel, Voltage-gated ion channel, Volume of distribution, Vomiting, Water, Wernicke–Korsakoff syndrome, Wine, Winemaking, Yeast, Yemen, Z-drug, Zolpidem, Zopiclone, 5-HT receptor, 5-HT3 receptor. Expand index (275 more) »

Acetaldehyde

Acetaldehyde (systematic name ethanal) is an organic chemical compound with the formula CH3CHO, sometimes abbreviated by chemists as MeCHO (Me.

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Acetaldehyde dehydrogenase

Acetaldehyde dehydrogenases are dehydrogenase enzymes which catalyze the conversion of acetaldehyde into acetic acid.

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Acetate

An acetate is a salt formed by the combination of acetic acid with an alkaline, earthy, metallic or nonmetallic and other base.

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Acetic acid

Acetic acid, systematically named ethanoic acid, is a colourless liquid organic compound with the chemical formula CH3COOH (also written as CH3CO2H or C2H4O2).

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Acetone

Acetone (systematically named propanone) is the organic compound with the formula (CH3)2CO.

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Acetyl-CoA

Acetyl-CoA (acetyl coenzyme A) is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism.

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Acetylcholine

Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals, including humans, as a neurotransmitter—a chemical message released by nerve cells to send signals to other cells.

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Active ingredient

An active ingredient (AI) is the ingredient in a pharmaceutical drug that is biologically active.

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Addiction

Addiction is a brain disorder characterized by compulsive engagement in rewarding stimuli despite adverse consequences.

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Adenosine reuptake inhibitor

An adenosine reuptake inhibitor (AdoRI) is a type of drug which acts as a reuptake inhibitor for the purine nucleoside and neurotransmitter adenosine by blocking the action of one or more of the equilibrative nucleoside transporters (ENTs).

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Adverse effect

In medicine, an adverse effect is an undesired harmful effect resulting from a medication or other intervention such as surgery.

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Afghanistan

Afghanistan (Pashto/Dari:, Pashto: Afġānistān, Dari: Afġānestān), officially the Islamic Republic of Afghanistan, is a landlocked country located within South Asia and Central Asia.

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Alcohol

In chemistry, an alcohol is any organic compound in which the hydroxyl functional group (–OH) is bound to a carbon.

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Alcohol abuse

Alcohol abuse is a previous psychiatric diagnosis in which there is recurring harmful use of alcohol despite its negative consequences.

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Alcohol and cancer

Alcoholic beverages are classified by the International Agency for Research on Cancer (IARC) as a Group 1 carcinogen (carcinogenic to humans).

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Alcohol dehydrogenase

Alcohol dehydrogenases (ADH) are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH).

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Alcohol dependence

Alcohol dependence is a previous psychiatric diagnosis in which an individual is physically or psychologically dependent upon alcohol (also known formally as ethanol).

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Alcohol detoxification

Alcohol detoxification, or detox, for individuals with alcohol dependence, is the abrupt cessation of alcohol intake, a process often coupled with substitution of cross-tolerant drugs that have effects similar to the effects of alcohol in order to prevent alcohol withdrawal.

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Alcohol flush reaction

Alcohol flush reaction is a condition in which a person develops flushes or blotches associated with erythema on the face, neck, shoulders, and in some cases, the entire body after consuming alcoholic beverages.

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Alcohol intoxication

Alcohol intoxication, also known as drunkenness or alcohol poisoning, is negative behavior and physical effects due to the recent drinking of ethanol (alcohol).

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Alcohol tolerance

Alcohol tolerance refers to the bodily responses to the functional effects of ethanol in alcoholic beverages.

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Alcoholic drink

An alcoholic drink (or alcoholic beverage) is a drink that contains ethanol, a type of alcohol produced by fermentation of grains, fruits, or other sources of sugar.

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Alcoholic liver disease

Alcoholic liver disease is a term that encompasses the liver manifestations of alcohol overconsumption, including fatty liver, alcoholic hepatitis, and chronic hepatitis with liver fibrosis or cirrhosis.

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Alcoholism

Alcoholism, also known as alcohol use disorder (AUD), is a broad term for any drinking of alcohol that results in mental or physical health problems.

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Aldehyde

An aldehyde or alkanal is an organic compound containing a functional group with the structure −CHO, consisting of a carbonyl center (a carbon double-bonded to oxygen) with the carbon atom also bonded to hydrogen and to an R group, which is any generic alkyl or side chain.

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Aldehyde dehydrogenase

Aldehyde dehydrogenases are a group of enzymes that catalyse the oxidation of aldehydes.

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Allergen

An allergen is a type of antigen that produces an abnormally vigorous immune response in which the immune system fights off a perceived threat that would otherwise be harmless to the body.

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Allergy

Allergies, also known as allergic diseases, are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment.

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Allosteric modulator

In biochemistry and pharmacology, an allosteric modulator (allo- from the Greek meaning "other") is a substance which indirectly influences (modulates) the effects of a primary ligand that directly activates or deactivates the function of a target protein.

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Allosteric regulation

In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule at a site other than the enzyme's active site.

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Amnesia

Amnesia is a deficit in memory caused by brain damage, disease, or psychological trauma.

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AMPA receptor

The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (also known as AMPA receptor, AMPAR, or quisqualate receptor) is an ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the central nervous system (CNS).

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Anesthetic

An anesthetic (or anaesthetic) is a drug to prevent pain during surgery, completely blocking any feeling as opposed to an analgesic.

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Antidepressant

Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.

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Antihistamine

Antihistamines are drugs which treat allergic rhinitis and other allergies.

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Antipsychotic

Antipsychotics, also known as neuroleptics or major tranquilizers, are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder.

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Antiseptic

Antiseptics (from Greek ἀντί anti, "against" and σηπτικός sēptikos, "putrefactive") are antimicrobial substances that are applied to living tissue/skin to reduce the possibility of infection, sepsis, or putrefaction.

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Anxiety

Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behaviour such as pacing back and forth, somatic complaints, and rumination.

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Anxiolytic

An anxiolytic (also antipanic or antianxiety agent) is a medication or other intervention that inhibits anxiety.

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Arrest

An arrest is the act of apprehending a person and taking them into custody, usually because they have been suspected of committing or planning a crime.

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Assault

An assault is the act of inflicting physical harm or unwanted physical contact upon a person or, in some specific legal definitions, a threat or attempt to commit such an action.

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Asthma

Asthma is a common long-term inflammatory disease of the airways of the lungs.

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Bangladesh

Bangladesh (বাংলাদেশ, lit. "The country of Bengal"), officially the People's Republic of Bangladesh (গণপ্রজাতন্ত্রী বাংলাদেশ), is a country in South Asia.

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Bar

A bar (also known as a saloon or a tavern or sometimes a pub or club, referring to the actual establishment, as in pub bar or savage club etc.) is a retail business establishment that serves alcoholic beverages, such as beer, wine, liquor, cocktails, and other beverages such as mineral water and soft drinks and often sell snack foods such as crisps (potato chips) or peanuts, for consumption on premises.

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Barbiturate

A barbiturate is a drug that acts as a central nervous system depressant, and can therefore produce a wide spectrum of effects, from mild sedation to death.

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Barley

Barley (Hordeum vulgare), a member of the grass family, is a major cereal grain grown in temperate climates globally.

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Beer

Beer is one of the oldest and most widely consumed alcoholic drinks in the world, and the third most popular drink overall after water and tea.

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Benzodiazepine

Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.

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Binding site

In biochemistry, a binding site is a region on a protein or piece of DNA or RNA to which ligands (specific molecules and/or ions) may form a chemical bond.

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Bioavailability

In pharmacology, bioavailability (BA or F) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.

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Biological half-life

The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.

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Biological membrane

A biological membrane or biomembrane is an enclosing or separating membrane that acts as a selectively permeable barrier within living things.

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Biological target

A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.

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Biotransformation

Biotransformation is the chemical modification (or modifications) made by an organism on a chemical compound.

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BK channel

BK channels (Big Potassium), also known as Maxi-K, slo1, or Kcal.1, are voltage-gated potassium channels that conduct large amounts of potassium ions (K+) across the cell membrane, hence their name, Big Potassium.

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Blood alcohol content

Blood alcohol content (BAC), also called blood alcohol concentration, blood ethanol concentration, or blood alcohol level, is most commonly used as a metric of alcohol intoxication for legal or medical purposes.

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Blood–brain barrier

The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).

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Bone

A bone is a rigid organ that constitutes part of the vertebrate skeleton.

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Brain

The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.

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Breathing

Breathing (or respiration, or ventilation) is the process of moving air into and out of the lungs to facilitate gas exchange with the internal environment, mostly by bringing in oxygen and flushing out carbon dioxide.

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Brewing

Brewing is the production of beer by steeping a starch source (commonly cereal grains, the most popular of which is barley) in water and fermenting the resulting sweet liquid with yeast.

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Bronchoconstriction

Bronchoconstriction is the constriction of the airways in the lungs due to the tightening of surrounding smooth muscle, with consequent coughing, wheezing, and shortness of breath.

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CAMK

CAMK, also written as CaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Cannabis

Cannabis is a genus of flowering plants in the family Cannabaceae.

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Carbohydrate

A carbohydrate is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water); in other words, with the empirical formula (where m may be different from n).

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Carbon dioxide

Carbon dioxide (chemical formula) is a colorless gas with a density about 60% higher than that of dry air.

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Carboxylic acid

A carboxylic acid is an organic compound that contains a carboxyl group (C(.

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Catalase

Catalase is a common enzyme found in nearly all living organisms exposed to oxygen (such as bacteria, plants, and animals).

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Central nervous system depression

Central nervous system depression or CNS depression refers to physiological depression of the central nervous system that can result in decreased rate of breathing, decreased heart rate, and loss of consciousness possibly leading to coma or death.

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Channel blocker

A channel blocker is the biological mechanism in which a particular molecule is used to prevent the opening of ion channels in order to produce a physiological response in a cell.

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Channel opener

A channel opener, also known as a channel activator, is a type of drug which facilitates ion flow through ion channels.

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Chemical compound

A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) composed of atoms from more than one element held together by chemical bonds.

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Chemical formula

A chemical formula is a way of presenting information about the chemical proportions of atoms that constitute a particular chemical compound or molecule, using chemical element symbols, numbers, and sometimes also other symbols, such as parentheses, dashes, brackets, commas and plus (+) and minus (−) signs.

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Chemical industry

The chemical industry comprises the companies that produce industrial chemicals.

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Chemical synapse

Chemical synapses are biological junctions through which neurons' signals can be exchanged to each other and to non-neuronal cells such as those in muscles or glands.

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Chloral hydrate

Chloral hydrate is a geminal diol with the formula C2H3Cl3O2.

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Chloralodol

Chloralodol (Chlorhexadol) is a hypnotic/sedative.

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Chloride

The chloride ion is the anion (negatively charged ion) Cl−.

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Chloroform

Chloroform, or trichloromethane, is an organic compound with formula CHCl3.

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Cholesterol

Cholesterol (from the Ancient Greek chole- (bile) and stereos (solid), followed by the chemical suffix -ol for an alcohol) is an organic molecule.

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Cirrhosis

Cirrhosis is a condition in which the liver does not function properly due to long-term damage.

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Clostridium difficile (bacteria)

Clostridium difficile (etymology and pronunciation), also known as C. difficile, C. diff, or sometimes CDF/cdf, is a species of Gram-positive spore-forming bacterium.

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Cmax (pharmacology)

Cmax is the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administrated and before the administration of a second dose.

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Cocaethylene

Cocaethylene (ethylbenzoylecgonine) is the ethyl ester of benzoylecgonine.

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Cocaine

Cocaine, also known as coke, is a strong stimulant mostly used as a recreational drug.

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Coenzyme A

Coenzyme A (CoA,SCoA,CoASH) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle.

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Cognition

Cognition is "the mental action or process of acquiring knowledge and understanding through thought, experience, and the senses".

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Cognitive deficit

Cognitive deficit or cognitive impairment is an inclusive term to describe any characteristic that acts as a barrier to the cognition process.

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Coma

Coma is a state of unconsciousness in which a person cannot be awaken; fails to respond normally to painful stimuli, light, or sound; lacks a normal wake-sleep cycle; and does not initiate voluntary actions.

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Combustibility and flammability

Flammable materials are those that ignite more easily than other materials, whereas those that are harder to ignite or burn less vigorously are combustible.

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Confusion

Confusion (from Latin confusĭo, -ōnis, from confundere: "to pour together;" "to mingle together;" "to confuse") is the state of being bewildered or unclear in one’s mind about something.

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Cornea

The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber.

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CREB

CREB (cAMP response element-binding protein) is a cellular transcription factor.

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CYP2E1

Cytochrome P450 2E1 (abbreviated CYP2E1) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body.

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Cytochrome P450

Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.

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Date rape drug

A date rape drug, also referred to as a predator drug, is any drug that is an incapacitating agent which, when administered to another person, incapacitates the person and renders them vulnerable to a drug facilitated sexual assault (DFSA), including rape.

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Delirium tremens

Delirium tremens (DTs) is a rapid onset of confusion usually caused by withdrawal from alcohol.

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Depressant

A depressant, or central depressant, is a drug that lowers neurotransmission levels, which is to depress or reduce arousal or stimulation, in various areas of the brain.

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Dermatitis

Dermatitis, also known as eczema, is a group of diseases that results in inflammation of the skin.

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Dexmethylphenidate

Dexmethylphenidate, sold under the trade names Focalin among others, is a central nervous system (CNS) stimulant used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.

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Diethyl ether

Diethyl ether, or simply ether, is an organic compound in the ether class with the formula, sometimes abbreviated as (see Pseudoelement symbols).

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Disease

A disease is any condition which results in the disorder of a structure or function in an organism that is not due to any external injury.

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Disinfectant

Disinfectants are antimicrobial agents that are applied to the surface of non-living objects to destroy microorganisms that are living on the objects.

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Distillation

Distillation is the process of separating the components or substances from a liquid mixture by selective boiling and condensation.

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Distribution (pharmacology)

Distribution in pharmacology is a branch of pharmacokinetics which describes the reversible transfer of a drug from one location to another within the body.

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Disulfiram

Disulfiram (sold under the trade names Antabuse and Antabus) is a drug used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol).

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Dizziness

Dizziness is an impairment in spatial perception and stability.

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Domestic violence

Domestic violence (also named domestic abuse or family violence) is violence or other abuse by one person against another in a domestic setting, such as in marriage or cohabitation.

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Dopamine

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.

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Dopamine receptor D1

Dopamine receptor D1, also known as DRD1, is a protein that in humans is encoded by the DRD1 gene.

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Dose–response relationship

The dose–response relationship, or exposure–response relationship, describes the change in effect on an organism caused by differing levels of exposure (or doses) to a stressor (usually a chemical) after a certain exposure time, or to a food.

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Downregulation and upregulation

In the biological context of organisms' production of gene products, downregulation is the process by which a cell decreases the quantity of a cellular component, such as RNA or protein, in response to an external stimulus.

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Drinking establishment

A drinking establishment is a business whose primary function is the serving of alcoholic beverages for consumption on the premises.

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Drug overdose

The term drug overdose (or simply overdose or OD) describes the ingestion or application of a drug or other substance in quantities greater than are recommended or generally practiced.

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Drug tolerance

Drug tolerance is a pharmacological concept describing subjects' reduced reaction to a drug following its repeated use.

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Drug withdrawal

Drug withdrawal is the group of symptoms that occur upon the abrupt discontinuation or decrease in intake of medications or recreational drugs.

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Drunk drivers

People driving under the influence of alcohol are commonly referred to as drunk drivers, or drink-drivers.

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Dysautonomia

Dysautonomia or autonomic dysfunction is a condition in which the autonomic nervous system (ANS) does not work properly.

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Egypt

Egypt (مِصر, مَصر, Khēmi), officially the Arab Republic of Egypt, is a transcontinental country spanning the northeast corner of Africa and southwest corner of Asia by a land bridge formed by the Sinai Peninsula.

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Elimination (pharmacology)

In pharmacology the elimination or excretion of a drug is understood to be any one of a number of processes by which a drug is eliminated (that is, cleared and excreted) from an organism either in an unaltered form (unbound molecules) or modified as a metabolite.

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Emergency department

An emergency department (ED), also known as an accident & emergency department (A&E), emergency room (ER), emergency ward (EW) or casualty department, is a medical treatment facility specializing in emergency medicine, the acute care of patients who present without prior appointment; either by their own means or by that of an ambulance.

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Empty calorie

In human nutrition, the term empty calories applies to foods and beverages composed primarily or solely of sugar, fats or oils, or alcohol-containing beverages.

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Endogeny (biology)

Endogenous substances and processes are those that originate from within an organism, tissue, or cell.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Enzyme inducer

An enzyme inducer is a type of drug that increases the metabolic activity of an enzyme either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme.

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Epileptic seizure

An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.

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Ethanol

Ethanol, also called alcohol, ethyl alcohol, grain alcohol, and drinking alcohol, is a chemical compound, a simple alcohol with the chemical formula.

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Ethchlorvynol

Ethchlorvynol is a GABA-ergic sedative and hypnotic/soporific medication developed by Pfizer in the 1950s.

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Ethyl glucuronide

Ethyl glucuronide (EtG) is a metabolite of ethanol which is formed in the body by glucuronidation following exposure to ethanol, usually from drinking alcoholic beverages.

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Ethyl group

In chemistry, an ethyl group is an alkyl substituent derived from ethane (C2H6).

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Ethyl sulfate

Ethyl sulfate (IUPAC name: ethyl hydrogen sulfate), also known as sulfovinic acid, is an organic chemical compound used as an intermediate in the production of ethanol from ethylene.

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Ethylene

Ethylene (IUPAC name: ethene) is a hydrocarbon which has the formula or H2C.

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Ethylene glycol

Ethylene glycol (IUPAC name: ethane-1,2-diol) is an organic compound with the formula (CH2OH)2.

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Euphoria

Euphoria is an affective state in which a person experiences pleasure or excitement and intense feelings of well-being and happiness.

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Fasting

Fasting is the willing abstinence or reduction from some or all food, drink, or both, for a period of time.

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Fat

Fat is one of the three main macronutrients, along with carbohydrate and protein.

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Fermentation

Fermentation is a metabolic process that consumes sugar in the absence of oxygen.

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Festival

A festival is an event ordinarily celebrated by a community and centering on some characteristic aspect of that community and its religion or cultures.

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Fever

Fever, also known as pyrexia and febrile response, is defined as having a temperature above the normal range due to an increase in the body's temperature set-point.

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Flumazenil

Flumazenil (also known as flumazepil, code name Ro 15-1788) is a selective benzodiazepine receptor antagonist available by injection and intranasal.

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Formaldehyde

No description.

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Formic acid

Formic acid, systematically named methanoic acid, is the simplest carboxylic acid.

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Fuel

A fuel is any material that can be made to react with other substances so that it releases energy as heat energy or to be used for work.

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G protein-coupled inwardly-rectifying potassium channel

The G protein-coupled inwardly-rectifying potassium channels (GIRKs) are a family of inward-rectifier potassium ion channels which are activated (opened) via a signal transduction cascade starting with ligand-stimulated G protein-coupled receptors (GPCRs).

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GABAA receptor

The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.

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GABRD

Gamma-aminobutyric acid receptor subunit delta is a protein that in humans is encoded by the GABRD gene.

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Gastrointestinal tract

The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.

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Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.

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General anaesthetic

General anaesthetics (or anesthetics, see spelling differences) are often defined as compounds that induce a reversible loss of consciousness in humans or loss of righting reflex in animals.

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Georgia (country)

Georgia (tr) is a country in the Caucasus region of Eurasia.

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Glutamic acid

Glutamic acid (symbol Glu or E) is an α-amino acid with formula.

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Glycine

Glycine (symbol Gly or G) is the amino acid that has a single hydrogen atom as its side chain.

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Glycine receptor

The glycine receptor (abbreviated as GlyR or GLR) is the receptor of the amino acid neurotransmitter glycine.

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Glycine reuptake inhibitor

A glycine reuptake inhibitor (GRI) is a type of drug which inhibits the reuptake of the neurotransmitter glycine by blocking one or more of the glycine transporters (GlyTs).

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Grape juice

Grape juice is obtained from crushing and blending grapes into a liquid.

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Hallucination

A hallucination is a perception in the absence of external stimulus that has qualities of real perception.

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Hangover

A hangover is the experience of various unpleasant physiological and psychological effects following the consumption of alcohol, such as wine, beer and distilled spirits.

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Happiness

In psychology, happiness is a mental or emotional state of well-being which can be defined by positive or pleasant emotions ranging from contentment to intense joy.

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Heart rate

Heart rate is the speed of the heartbeat measured by the number of contractions of the heart per minute (bpm).

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Hepatotoxicity

Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.

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High-density lipoprotein

High-density lipoproteins (HDL) are one of the five major groups of lipoproteins.

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Histamine

Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus.

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Hives

Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps.

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Human

Humans (taxonomically Homo sapiens) are the only extant members of the subtribe Hominina.

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Human body weight

Human body weight refers to a person's mass or weight.

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Hydration reaction

In chemistry, a hydration reaction is a chemical reaction in which a substance combines with water.

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Hydroxy group

A hydroxy or hydroxyl group is the entity with the formula OH.

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Hypnotic

Hypnotic (from Greek Hypnos, sleep) or soporific drugs, commonly known as sleeping pills, are a class of psychoactive drugs whose primary function is to induce sleep and to be used in the treatment of insomnia (sleeplessness), or surgical anesthesia.

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Hypoventilation

Hypoventilation (also known as respiratory depression) occurs when ventilation is inadequate (hypo meaning "below") to perform needed gas exchange.

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India

India (IAST), also called the Republic of India (IAST), is a country in South Asia.

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Indian reservation

An Indian reservation is a legal designation for an area of land managed by a federally recognized Native American tribe under the U.S. Bureau of Indian Affairs rather than the state governments of the United States in which they are physically located.

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Inhalation

Inhalation (also known as inspiration) happens when oxygen from the air enters the lungs.

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Inhalational anaesthetic

An inhalational anaesthetic is a chemical compound possessing general anaesthetic properties that can be delivered via inhalation.

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Injection (medicine)

Injection (often referred to as a "shot" in US English, or a "jab" in UK English) is the act of putting a liquid, especially a drug, into a person's body using a needle (usually a hypodermic needle) and a syringe.

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Injury

Injury, also known as physical trauma, is damage to the body caused by external force.

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Insomnia

Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping.

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International Agency for Research on Cancer

The International Agency for Research on Cancer (IARC; Centre International de Recherche sur le Cancer, CIRC) is an intergovernmental agency forming part of the World Health Organization of the United Nations.

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Intestinal mucosal barrier

The intestinal mucosal barrier, also referred to as intestinal barrier, refers to the property of the intestinal mucosa that ensures adequate containment of undesirable luminal contents within the intestine while preserving the ability to absorb nutrients.

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Intimate partner violence

Intimate partner violence (IPV) is domestic violence by a current or former spouse or partner in an intimate relationship against the other spouse or partner.

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Intravenous therapy

Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).

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Ion channel

Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore.

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Ionotropic glutamate receptor

Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate.

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Iran

Iran (ایران), also known as Persia, officially the Islamic Republic of Iran (جمهوری اسلامی ایران), is a sovereign state in Western Asia. With over 81 million inhabitants, Iran is the world's 18th-most-populous country. Comprising a land area of, it is the second-largest country in the Middle East and the 17th-largest in the world. Iran is bordered to the northwest by Armenia and the Republic of Azerbaijan, to the north by the Caspian Sea, to the northeast by Turkmenistan, to the east by Afghanistan and Pakistan, to the south by the Persian Gulf and the Gulf of Oman, and to the west by Turkey and Iraq. The country's central location in Eurasia and Western Asia, and its proximity to the Strait of Hormuz, give it geostrategic importance. Tehran is the country's capital and largest city, as well as its leading economic and cultural center. Iran is home to one of the world's oldest civilizations, beginning with the formation of the Elamite kingdoms in the fourth millennium BCE. It was first unified by the Iranian Medes in the seventh century BCE, reaching its greatest territorial size in the sixth century BCE, when Cyrus the Great founded the Achaemenid Empire, which stretched from Eastern Europe to the Indus Valley, becoming one of the largest empires in history. The Iranian realm fell to Alexander the Great in the fourth century BCE and was divided into several Hellenistic states. An Iranian rebellion culminated in the establishment of the Parthian Empire, which was succeeded in the third century CE by the Sasanian Empire, a leading world power for the next four centuries. Arab Muslims conquered the empire in the seventh century CE, displacing the indigenous faiths of Zoroastrianism and Manichaeism with Islam. Iran made major contributions to the Islamic Golden Age that followed, producing many influential figures in art and science. After two centuries, a period of various native Muslim dynasties began, which were later conquered by the Turks and the Mongols. The rise of the Safavids in the 15th century led to the reestablishment of a unified Iranian state and national identity, with the country's conversion to Shia Islam marking a turning point in Iranian and Muslim history. Under Nader Shah, Iran was one of the most powerful states in the 18th century, though by the 19th century, a series of conflicts with the Russian Empire led to significant territorial losses. Popular unrest led to the establishment of a constitutional monarchy and the country's first legislature. A 1953 coup instigated by the United Kingdom and the United States resulted in greater autocracy and growing anti-Western resentment. Subsequent unrest against foreign influence and political repression led to the 1979 Revolution and the establishment of an Islamic republic, a political system that includes elements of a parliamentary democracy vetted and supervised by a theocracy governed by an autocratic "Supreme Leader". During the 1980s, the country was engaged in a war with Iraq, which lasted for almost nine years and resulted in a high number of casualties and economic losses for both sides. According to international reports, Iran's human rights record is exceptionally poor. The regime in Iran is undemocratic, and has frequently persecuted and arrested critics of the government and its Supreme Leader. Women's rights in Iran are described as seriously inadequate, and children's rights have been severely violated, with more child offenders being executed in Iran than in any other country in the world. Since the 2000s, Iran's controversial nuclear program has raised concerns, which is part of the basis of the international sanctions against the country. The Joint Comprehensive Plan of Action, an agreement reached between Iran and the P5+1, was created on 14 July 2015, aimed to loosen the nuclear sanctions in exchange for Iran's restriction in producing enriched uranium. Iran is a founding member of the UN, ECO, NAM, OIC, and OPEC. It is a major regional and middle power, and its large reserves of fossil fuels – which include the world's largest natural gas supply and the fourth-largest proven oil reserves – exert considerable influence in international energy security and the world economy. The country's rich cultural legacy is reflected in part by its 22 UNESCO World Heritage Sites, the third-largest number in Asia and eleventh-largest in the world. Iran is a multicultural country comprising numerous ethnic and linguistic groups, the largest being Persians (61%), Azeris (16%), Kurds (10%), and Lurs (6%).

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Irritation

Irritation, in biology and physiology, is a state of inflammation or painful reaction to allergy or cell-lining damage.

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Isoflurane

Isoflurane, sold under the trade name Forane among others, is a general anesthetic.

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Isopropyl alcohol

Isopropyl alcohol (IUPAC name propan-2-ol; commonly called isopropanol) is a compound with the chemical formula C3H8O.

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Kainate receptor

Kainate receptors, or kainic acid receptors (KARs), are ionotropic receptors that respond to the neurotransmitter glutamate.

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KEGG

KEGG (Kyoto Encyclopedia of Genes and Genomes) is a collection of databases dealing with genomes, biological pathways, diseases, drugs, and chemical substances.

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Ketone

In chemistry, a ketone (alkanone) is an organic compound with the structure RC(.

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Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

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Kuwait

Kuwait (الكويت, or), officially the State of Kuwait (دولة الكويت), is a country in Western Asia.

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L-type calcium channel

The L-type calcium channel (also known as the dihydropyridine channel, or DHP channel) is part of the high-voltage activated family of voltage-dependent calcium channel.

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Libya

Libya (ليبيا), officially the State of Libya (دولة ليبيا), is a sovereign state in the Maghreb region of North Africa, bordered by the Mediterranean Sea to the north, Egypt to the east, Sudan to the southeast, Chad and Niger to the south and Algeria and Tunisia to the west.

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Life expectancy

Life expectancy is a statistical measure of the average time an organism is expected to live, based on the year of its birth, its current age and other demographic factors including gender.

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Ligand-gated ion channel

Ligand-gated ion channels (LICs, LGIC), also commonly referred as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow ions such as Na+, K+, Ca2+, and/or Cl− to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand), such as a neurotransmitter.

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Liquid

A liquid is a nearly incompressible fluid that conforms to the shape of its container but retains a (nearly) constant volume independent of pressure.

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Liquor

Liquor (also hard liquor, hard alcohol, or spirits) is an alcoholic drink produced by distillation of grains, fruit, or vegetables that have already gone through alcoholic fermentation.

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Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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MAPK/ERK pathway

The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in the nucleus of the cell.

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Marital breakdown

Marital breakdown refers to the common process whereby the relationship between a married couple erodes, such that they cannot ordinarily restore their relationship.

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Mechanism of action

In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect.

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Median lethal dose

In toxicology, the median lethal dose, LD50 (abbreviation for "lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 is a measure of the lethal dose of a toxin, radiation, or pathogen.

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Memory

Memory is the faculty of the mind by which information is encoded, stored, and retrieved.

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Mesolimbic pathway

The mesolimbic pathway, sometimes referred to as the reward pathway, is a dopaminergic pathway in the brain.

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Metabolic pathway

In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell.

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Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.

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Metabolite

A metabolite is the intermediate end product of metabolism.

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Methanol

Methanol, also known as methyl alcohol among others, is a chemical with the formula CH3OH (a methyl group linked to a hydroxyl group, often abbreviated MeOH).

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Methylpentynol

Methylpentynol (Methylparafynol, Dormison, Atemorin, Oblivon) is a tertiary hexanol with hypnotic/sedative and anticonvulsant effects and an exceptionally low therapeutic index.

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Methylphenidate

Methylphenidate, sold under various trade names, Ritalin being one of the most commonly known, is a central nervous system (CNS) stimulant of the phenethylamine and piperidine classes that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.

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Metronidazole

Metronidazole, marketed under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication.

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Middle East

The Middle Easttranslit-std; translit; Orta Şərq; Central Kurdish: ڕۆژھەڵاتی ناوین, Rojhelatî Nawîn; Moyen-Orient; translit; translit; translit; Rojhilata Navîn; translit; Bariga Dhexe; Orta Doğu; translit is a transcontinental region centered on Western Asia, Turkey (both Asian and European), and Egypt (which is mostly in North Africa).

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Mixture

In chemistry, a mixture is a material made up of two or more different substances which are mixed.

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Molar concentration

Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular of a solute in a solution, in terms of amount of substance per unit volume of solution.

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Molasses

Molasses, or black treacle (British, for human consumption; known as molasses otherwise), is a viscous product resulting from refining sugarcane or sugar beets into sugar.

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Molecular mass

Relative Molecular mass or molecular weight is the mass of a molecule.

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Mortality rate

Mortality rate, or death rate, is a measure of the number of deaths (in general, or due to a specific cause) in a particular population, scaled to the size of that population, per unit of time.

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Motor control

Motor control is the systematic regulation of movement in organisms that possess a nervous system.

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Murder

Murder is the unlawful killing of another human without justification or valid excuse, especially the unlawful killing of another human being with malice aforethought.

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N-Butanol

n-Butanol or n-butyl alcohol or normal butanol is a primary alcohol with a 4-carbon structure and the chemical formula C4H9OH.

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National Institute on Alcohol Abuse and Alcoholism

The National Institute on Alcohol Abuse and Alcoholism (NIAAA), as part of the U.S. National Institutes of Health, supports and conducts biomedical and behavioral research on the causes, consequences, treatment, and prevention of alcoholism and alcohol-related problems.

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Natural product

A natural product is a chemical compound or substance produced by a living organism—that is, found in nature.

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Nausea

Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.

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Necessity and sufficiency

In logic, necessity and sufficiency are terms used to describe an implicational relationship between statements.

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Neurotoxicity

Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the structure or function of the central and/or peripheral nervous system.

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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission.

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Nicotinamide adenine dinucleotide

Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in all living cells.

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Nicotinic acetylcholine receptor

Nicotinic acetylcholine receptors, or nAChRs, are receptor proteins that respond to the neurotransmitter acetylcholine.

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Nightclub

A nightclub, music club or club, is an entertainment venue and bar that usually operates late into the night.

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NMDA receptor

The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and ion channel protein found in nerve cells.

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Nonbenzodiazepine

Nonbenzodiazepines (sometimes referred to colloquially as "Z-drugs") are a class of psychoactive drugs that are very benzodiazepine-like in nature.

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Northern and southern China

Northern China and southern China are two approximate regions within China. The exact boundary between these two regions are not precisely defined. Nevertheless, the self-perception of Chinese people, especially regional stereotypes, has often been dominated by these two concepts, given that regional differences in culture and language have historically fostered strong regional identities of the Chinese people.

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Nucleus accumbens

The nucleus accumbens (NAc or NAcc), also known as the accumbens nucleus, or formerly as the nucleus accumbens septi (Latin for nucleus adjacent to the septum) is a region in the basal forebrain rostral to the preoptic area of the hypothalamus.

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Odor

An odor, odour or fragrance is always caused by one or more volatilized chemical compounds.

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Opioid

Opioids are substances that act on opioid receptors to produce morphine-like effects.

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Oral administration

| name.

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Organic brain syndrome

An organic brain syndrome (OBS), also known as an organic brain disease/disorder (OBD), an organic mental syndrome (OMS), or an organic mental disorder (OMD), is a syndrome or disorder of mental function whose cause is alleged to be known as organic (physiologic) rather than purely of the mind.

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Paraldehyde

Paraldehyde is the cyclic trimer of acetaldehyde molecules.

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Party

A party is a gathering of people who have been invited by a host for the purposes of socializing, conversation, recreation, or as part of a festival or other commemoration of a special occasion.

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Passive transport

Passive transport is a movement of ions and other atomic or molecular substances across cell membranes without need of energy input.

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Peptic ulcer disease

Peptic ulcer disease (PUD) is a break in the lining of the stomach, first part of the small intestine or occasionally the lower esophagus.

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Perspiration

Perspiration, also known as sweating, is the production of fluids secreted by the sweat glands in the skin of mammals.

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Petrochemical

Petrochemicals (also known as petroleum distillates) are chemical products derived from petroleum.

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Pharmacodynamics

Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).

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Phosphorylation

In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.

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Physical disability

A physical disability is a limitation on a person's physical functioning, mobility, dexterity or stamina.

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Plasma protein binding

Plasma protein binding refers to the degree to which medications attach to proteins within the blood.

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Pleasure

Pleasure is a broad class of mental states that humans and other animals experience as positive, enjoyable, or worth seeking.

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Pliny the Elder

Pliny the Elder (born Gaius Plinius Secundus, AD 23–79) was a Roman author, naturalist and natural philosopher, a naval and army commander of the early Roman Empire, and friend of emperor Vespasian.

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Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

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Primary alcohol

A primary alcohol is an alcohol which has the hydroxyl group connected to a primary carbon atom.

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Properties of water

Water is a polar inorganic compound that is at room temperature a tasteless and odorless liquid, which is nearly colorless apart from an inherent hint of blue. It is by far the most studied chemical compound and is described as the "universal solvent" and the "solvent of life". It is the most abundant substance on Earth and the only common substance to exist as a solid, liquid, and gas on Earth's surface. It is also the third most abundant molecule in the universe. Water molecules form hydrogen bonds with each other and are strongly polar. This polarity allows it to separate ions in salts and strongly bond to other polar substances such as alcohols and acids, thus dissolving them. Its hydrogen bonding causes its many unique properties, such as having a solid form less dense than its liquid form, a relatively high boiling point of 100 °C for its molar mass, and a high heat capacity. Water is amphoteric, meaning that it is both an acid and a base—it produces + and - ions by self-ionization.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein kinase A

In cell biology, protein kinase A (PKANot to be confused with pKa, the symbol for the acid dissociation constant.) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP).

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Protein subunit

In structural biology, a protein subunit is a single protein molecule that assembles (or "coassembles") with other protein molecules to form a protein complex.

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Psychoactive drug

A psychoactive drug, psychopharmaceutical, or psychotropic is a chemical substance that changes brain function and results in alterations in perception, mood, consciousness, cognition, or behavior.

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Psychomotor agitation

Psychomotor agitation is a set of signs and symptoms that stem from mental tension and anxiety.

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Pulmonary edema

Pulmonary edema is fluid accumulation in the tissue and air spaces of the lungs.

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Race (human categorization)

A race is a grouping of humans based on shared physical or social qualities into categories generally viewed as distinct by society.

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Rape

Rape is a type of sexual assault usually involving sexual intercourse or other forms of sexual penetration carried out against a person without that person's consent.

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Rate equation

The rate law or rate equation for a chemical reaction is an equation that links the reaction rate with the concentrations or pressures of the reactants and constant parameters (normally rate coefficients and partial reaction orders).

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Receptor (biochemistry)

In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.

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Recreational drug use

Recreational drug use is the use of a psychoactive drug to induce an altered state of consciousness for pleasure, by modifying the perceptions, feelings, and emotions of the user.

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Rectal administration

Rectal administration uses the rectum as a route of administration for medication and other fluids, which are absorbed by the rectum's blood vessels,The rectum has numerous blood vessels available to absorb drugs.

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Redox

Redox (short for reduction–oxidation reaction) (pronunciation: or) is a chemical reaction in which the oxidation states of atoms are changed.

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Reinforcement

In behavioral psychology, reinforcement is a consequence that will strengthen an organism's future behavior whenever that behavior is preceded by a specific antecedent stimulus.

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Respiratory failure

Respiratory failure results from inadequate gas exchange by the respiratory system, meaning that the arterial oxygen, carbon dioxide or both cannot be kept at normal levels.

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Rhinitis

Rhinitis, also known as coryza, is irritation and inflammation of the mucous membrane inside the nose.

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Ro15-4513

Ro15-4513 is a weak partial inverse agonist of the benzodiazepine class of drugs, developed by Hoffmann–La Roche in the 1980s.

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Rome

Rome (Roma; Roma) is the capital city of Italy and a special comune (named Comune di Roma Capitale).

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Saccharomyces cerevisiae

Saccharomyces cerevisiae is a species of yeast.

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Saudi Arabia

Saudi Arabia, officially the Kingdom of Saudi Arabia (KSA), is a sovereign Arab state in Western Asia constituting the bulk of the Arabian Peninsula.

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Sedation

Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.

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Sedative

A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement.

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Sense

A sense is a physiological capacity of organisms that provides data for perception.

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Sensory loss

Many types of sense loss occur due to a dysfunctional sensation process, whether it be ineffective receptors, nerve damage, or cerebral impairment.

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Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

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Sexual assault

Sexual assault is an act in which a person coerces or physically forces a person to engage in a sexual act against their will.

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Small intestine

The small intestine or small bowel is the part of the gastrointestinal tract between the stomach and the large intestine, and is where most of the end absorption of food takes place.

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Social behavior

Social behavior is behavior among two or more organisms, typically from the same species.

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Solvent

A solvent (from the Latin solvō, "loosen, untie, solve") is a substance that dissolves a solute (a chemically distinct liquid, solid or gas), resulting in a solution.

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Somalia

Somalia (Soomaaliya; aṣ-Ṣūmāl), officially the Federal Republic of SomaliaThe Federal Republic of Somalia is the country's name per Article 1 of the.

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Stimulant

Stimulants (also often referred to as psychostimulants or colloquially as uppers) is an overarching term that covers many drugs including those that increase activity of the central nervous system and the body, drugs that are pleasurable and invigorating, or drugs that have sympathomimetic effects.

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Stomach

The stomach (from ancient Greek στόμαχος, stomachos, stoma means mouth) is a muscular, hollow organ in the gastrointestinal tract of humans and many other animals, including several invertebrates.

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Structural analog

A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.

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Stupor

Stupor (from Latin stupere, "be stunned or amazed") is the lack of critical mental function and a level of consciousness wherein a sufferer is almost entirely unresponsive and only responds to base stimuli such as pain.

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Substance dependence

Substance dependence also known as drug dependence is an adaptive state that develops from repeated drug administration, and which results in withdrawal upon cessation of drug use.

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Sudan

The Sudan or Sudan (السودان as-Sūdān) also known as North Sudan since South Sudan's independence and officially the Republic of the Sudan (جمهورية السودان Jumhūriyyat as-Sūdān), is a country in Northeast Africa.

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Sugar

Sugar is the generic name for sweet-tasting, soluble carbohydrates, many of which are used in food.

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Sugarcane

Sugarcane, or sugar cane, are several species of tall perennial true grasses of the genus Saccharum, tribe Andropogoneae, native to the warm temperate to tropical regions of South and Southeast Asia, Polynesia and Melanesia, and used for sugar production.

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Sugarcane juice

Sugarcane juice is the syrup extracted from pressed sugarcane.

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Teratology

Teratology is the study of abnormalities of physiological development.

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Tert-Amyl alcohol

tert-Amyl alcohol (TAA), systematic name: 2-methylbutan-2-ol (2M2B), is a branched pentanol.

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Tetrahydrocannabinol

Tetrahydrocannabinol (THC) is one of at least 113 cannabinoids identified in cannabis.

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Toxicity

Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism.

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Traffic collision

A traffic collision, also called a motor vehicle collision (MVC) among other terms, occurs when a vehicle collides with another vehicle, pedestrian, animal, road debris, or other stationary obstruction, such as a tree, pole or building.

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Transcaucasia

Transcaucasia (Закавказье), or the South Caucasus, is a geographical region in the vicinity of the southern Caucasus Mountains on the border of Eastern Europe and Western Asia.

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Transparency and translucency

In the field of optics, transparency (also called pellucidity or diaphaneity) is the physical property of allowing light to pass through the material without being scattered.

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Tremor

A tremor is an involuntary, somewhat rhythmic, muscle contraction and relaxation involving oscillations or twitching movements of one or more body parts.

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Triglyceride

A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids (from tri- and glyceride).

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Unconsciousness

Unconsciousness is a state which occurs when the ability to maintain an awareness of self and environment is lost.

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United States

The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.

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Urine

Urine is a liquid by-product of metabolism in humans and in many animals.

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Vapor

In physics a vapor (American) or vapour (British and Canadian) is a substance in the gas phase at a temperature lower than its critical temperature,R.

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Ventral tegmental area

The ventral tegmental area (VTA) (tegmentum is Latin for covering), also known as the ventral tegmental area of Tsai, or simply ventral tegmentum, is a group of neurons located close to the midline on the floor of the midbrain.

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Vineyard

A vineyard is a plantation of grape-bearing vines, grown mainly for winemaking, but also raisins, table grapes and non-alcoholic grape juice.

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Violent crime

A violent crime or crime of violence is a crime in which an offender or perpetrator uses or threatens to use force upon a victim.

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Volatility (chemistry)

In chemistry and physics, volatility is quantified by the tendency of a substance to vaporize.

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Voltage-gated calcium channel

Voltage-gated calcium channels (VGCCs), also known as voltage-dependent calcium channels (VDCCs), are a group of voltage-gated ion channels found in the membrane of excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the calcium ion Ca2+.

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Voltage-gated ion channel

Voltage-gated ion channels are a class of transmembrane proteins that form ion channels that are activated by changes in the electrical membrane potential near the channel.

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Volume of distribution

In pharmacology, the volume of distribution (VD, also known as apparent volume of distribution) is the theoretical volume that would be necessary to contain the total amount of an administered drug at the same concentration that it is observed in the blood plasma.

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Vomiting

Vomiting, also known as emesis, puking, barfing, throwing up, among other terms, is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.

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Water

Water is a transparent, tasteless, odorless, and nearly colorless chemical substance that is the main constituent of Earth's streams, lakes, and oceans, and the fluids of most living organisms.

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Wernicke–Korsakoff syndrome

Wernicke–Korsakoff syndrome (WKS) is the combined presence of Wernicke encephalopathy (WE) and alcoholic Korsakoff syndrome.

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Wine

Wine is an alcoholic beverage made from grapes fermented without the addition of sugars, acids, enzymes, water, or other nutrients.

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Winemaking

Winemaking or vinification is the production of wine, starting with the selection of the fruit, its fermentation into alcohol, and the bottling of the finished liquid.

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Yeast

Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom.

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Yemen

Yemen (al-Yaman), officially known as the Republic of Yemen (al-Jumhūriyyah al-Yamaniyyah), is an Arab sovereign state in Western Asia at the southern end of the Arabian Peninsula.

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Z-drug

Z-drugs are a group of nonbenzodiazepine drugs with effects similar to benzodiazepines, which are used in the treatment of trouble sleeping, and most of whose names start with the letter "Z".

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Zolpidem

Zolpidem, sold under the brand name Ambien, among others, is a sedative primarily used for the treatment of trouble sleeping.

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Zopiclone

--> Zopiclone (brand names Imovane, Zimovane, Dopareel) is a nonbenzodiazepine hypnotic agent used in the treatment of insomnia.

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5-HT receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems.

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5-HT3 receptor

The 5-HT3 receptor belongs to the Cys-loop superfamily of ligand-gated ion channels (LGICs) and therefore differs structurally and functionally from all other 5-HT receptors (5-hydroxytryptamine, or serotonin) receptors which are G protein-coupled receptors.

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Alcohol (psychoactive drug), Alcohol (psychoactive substance), Alcohol (recreational drug), Alcohol (recreational substance), Alcohol (substance), Drinking alcohol, Ethanol (drug), Ethyl alcohol (drug).

References

[1] https://en.wikipedia.org/wiki/Alcohol_(drug)

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